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Chinese Journal of Aeronautics 2024年第10期37卷 435-444页

作者： Qi zhoNG Junxian WANG Enguang xu Cheng YU Yanbiao LI College of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310023China Key Laboratory of Special Purpose Equipment and Advanced Processing Technology Ministry of Education and Zhejiang ProvinceZhejiang University of TechnologyHangzhou 310023China

Hydraulic circuits with high speed on/off valve(HSV)for servo control have become commonplace in ***,the individual valve that is not volume-optimized results in a large total size of hydraulic control system,diminishing the *** address this issue,the high-precision equivalent reluctance model of the HSV is established by employing an equivalent magnetic circuit,on which the dynamic characteristic of the HSV,as well as the effects of structural parameters on switching behaviour,are *** on this model,multi-objective optimization is adopted to design an HSV with faster dynamic performance and smaller volume,NSGA-II genetic algorithm is applied to obtain the Pareto front of the desired *** assess the impact before and after optimization,an HSV based on the optimized structure is manufactured and *** experimental results show that the optimized HSV reduces 47.1%of its solenoid volume while improving opening and closing dynamic performance by 14.8%and 43.0%respectively,increasing maximum switching frequency by 6.2%,and expanding flow linear control area by 6.7%.These results validate the optimized structure and indicate that the optimization method provided in the paper is beneficial for developing superior HSV.

关键词： High speed on/off valve Dynamic response Volume Multiobjective optimization NSGA-II genetic algorithm

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“如果”句功能的类型学考察

汉语学习 2024年第2期 22-32页

作者：吴炳章姜彩璨许冰中国海洋大学外国语学院山东青岛266100

“如果”句的语义结构和用法复杂多样,但学界对该结构的功能类型分析过于笼统。文章通过语料库梳理书面语中“如果”句的结构特点和语篇关系,对其进行了功能分类。从功能视角看,“如果”句在知识域、语言域和人际域中分别发挥前提限定... 详细信息

“如果”句的语义结构和用法复杂多样,但学界对该结构的功能类型分析过于笼统。文章通过语料库梳理书面语中“如果”句的结构特点和语篇关系,对其进行了功能分类。从功能视角看,“如果”句在知识域、语言域和人际域中分别发挥前提限定、语篇建构和会话修辞等功能。根据从句和主句的意义关系,“如果”句可以分为蕴含条件句和非蕴含条件句。各类“如果”句的功能各有句法语义特征。从各类“如果”句的用法分布看,“如果”句的主要功能是表达推理关系,其次是语篇关系,再次是话语修辞。

关键词： “如果”句假设条件句间接条件句

New perspective on the treatment of rheumatic arthritis based on“strengthening body resistance(Fúzhèng)”in the theory of co-inhibitory receptor-regulated T-cell immunity

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Acupuncture and Herbal Medicine 2024年第3期4卷 290-294页

作者： Yifei xu Linda zhong Qianqian Liang Hao xu Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine Shanghai University of Traditional Chinese MedicineShanghaiChina Biomedical Sciences and Chinese Medicine School of Biological ScienceNanyang Technological UniversitySingaporeSingapore Spine Institute Shanghai University of Traditional Chinese MedicineShanghaiChina Key Laboratory of Theory and Therapy of Muscles and Bones Ministry of Education(Shanghai University of Traditional Chinese Medicine)ShanghaiChina

Co-inhibitory receptors serve as crucial regulators of T-cell function,playing a pivotal role in modulating the delicate balance between immune tolerance and *** identified in autoimmune disease models,co-inhibitory receptors,including CTLA-4,PD-1,TIM-3,and TIGIT,were found to be integral to immune *** blockade or absence in these models resulted in the induction or exacerbation of autoimmune ***,scholars have observed that co-inhibitory receptors on lymphocytes hold the potential to influence the prognosis in the context of chronic ***,the blocking of co-suppressor receptors has emerged as a novel therapeutic approach for inhibiting refractory inflammatory diseases,particularly rheumatoid *** the standpoint of traditional Chinese medicine(TCM),the treatment of rheumatoid arthritis based on the“strengthening body resistance(Fúzhèng)”theory can be construed as the regulation of co-suppressor receptors to modulate the body’s immune function in combating chronic *** article provides a succinct overview of the role of co-suppressor receptors in anti-inflammatory processes and explores the research prospects of co-suppressor receptor intervention in the treatment of rheumatoid *** exploration integrates the“strengthening body resistance(Fúzhèng)”theory with relevant Chinese medicine formulations.

关键词： Combination of Chinese and Western Medicine Co-inhibitory receptors Rheumatic arthritis T-cell exhaustion

Credit risk prediction for small and medium enterprises utilizing adjacent enterprise data and a relational graph attention network

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Journal of Management Science and Engineering 2024年第2期9卷 177-192页

作者： Jiaxing Wang Guoquan Liu Xiaobo xu Xinjie Xing International Business School Suzhou Xi'an Jiaotong-Liverpool UniversitySuzhou215028China Financial Technology Research Institute Fudan UniversityShanghai200433China Management School University of LiverpoolChatham StreetLiverpoolL697ZHUK

Credit risk prediction for small and medium enterprises(SMEs)has long posed a complex research *** approaches have primarily focused on enterprise-specific variables,but these models often prove inadequate when applied to SMEs with incomplete *** this innovative study,we push the theoretical boundaries by leveraging data from adjacent enterprises to address the issue of data *** strategy involves constructing an intricate network that interconnects enterprises based on shared managerial teams and business *** this network,we propose a novel relational graph attention network(RGAT)algorithm capable of capturing the inherent complexity in its topological *** doing so,our model enhances financial service providers'ability to predict credit risk even in the face of incomplete data from target *** experiments conducted using China's SMEs highlight the predictive proficiency and potential economic benefits of our proposed *** approach offers a comprehensive and nuanced perspective on credit risk while demonstrating the advantages of incorporating network-wide data in credit risk prediction.

关键词： Risk management SMEC redit risk Transactional data Graph neural network

Switching Frequency Improvement of a High Speed on/off Valve Based on Pre-excitation Control Algorithm

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Chinese Journal of Mechanical Engineering 2024年第4期37卷 94-106页

作者： Qi zhong Xiaotian Li Yongxin Mao Enguang xu Tiwei Jia Yanbiao Li Huayong Yang College of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310023China State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou 310027China Key Laboratory of Special Purpose Equipment and Advanced Processing Technology Ministry of Education and Zhejiang ProvinceZhejiang University of TechnologyHangzhou 310023China

The high-speed on/off valve(HSV)serves as the fundamental component responsible for generating discrete fluids within digital hydraulic *** the switching frequency of the HSV increases,the properties of the generated discrete fluid approach those of continuous ***,a higher frequency response characteristic of HSV is the key to ensure the control accuracy of digital hydraulic ***,the current research mainly focuses on its dynamic performance,but neglect its *** paper presents a theoretical analysis demonstrating that the FRC of the HSV can be enhanced by minimizing its switching *** maximum switching frequency(MSF)is mainly determined by opening dynamic performance when HSV operates with low switching duty ratio(SDR),whereas the closing dynamic performance limits the MSF when HSV operates with high *** upon these findings,the pre-excitation control algorithm(PECA)is proposed to reduce the switching time of the HSV,and consequently enhance its *** results demonstrate that PECA shortens the opening delay time of HSV by 1.12 ms,the closing delay time by 2.54 ms,and the closing moving time by 0.47 ms in comparison to the existing advanced control *** a result,a larger MSF of 417 Hz and a wider controllable SDR range from 20%to 70%were achieved at a switching frequency of 250 ***,the proposed PFCA in this paper has been verified as an effective and promising approach for enhancing the control performance of digital hydraulic systems.

关键词： High speed on/off valve Switching frequency Pre-excitation Dynamic performance Switching duty ratio

Serum deprivation enhances DNA synthesis of human hepatoma SMMC-7721 cells

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World Journal of Gastroenterology 1998年第2期4卷 29-32页

作者： Jiang, SM xu, zh Shandong Normal Univ Dept Biol Provincial Key Lab Anim Stress Jinan 250014 Shandong Provin Peoples R China

AIM To determine the relationship between serum deprivation or serum levels and cell proliferation of human hepatoma SMMC 7721 cells. METHoDS Human hepatoma SMMC 7721 cells were grown in RPMI 1640 supplemented with 10% fetal calf (FCS) in 5% Co 2 incubator at 37℃ for 24h , and culture media were replaced to serum free or different serum FCS levels (2 5%, 5%, 10%, 20% and 25%). Six h, 12h , 18h and 24h after the culture, the cells were incorporated TdR for 4h . At last TdR incorporation was detected with liquid scintillation counting. RESULTS DNA synthesis of SMMC 7721 cells could be sharply stimulated by short time (6h) serum deprivation (the cpm value of 3H TdR incorporation of cells in serum free was 39 32 fold higher than cells in 25% serum), and the incorporation of 3H TdR was negatively related to the serum levels. Longer time serum starvation ( 12h , 18h and 24h ) also greatly stimulated DNA synthesis, although the cpm value of 3H TdR incroporation was less than that in 6h serum deprivation. Morphology of cells cultured in different serum levels also showed significant difference. CoNCLUSIoNS Compared with other cell lines such as BEL7404 and Swiss 3T3, human hepatoma SMMC 7721 cells had different response to the serum deprivation. Short time serum deprivation could greatly stimulate DNA synthesis of human hepatoma SMMC 7721 cells. Precautions must be given to the changes of serum levels for the detection of growth factors and drugs using SMMC 7721 cells as a model.

关键词： liver neoplasms carcinoma, hepatocellular DNA, neoplasm/biosynthesis SMMC 7721 tumor cell, cultured cell proliferation growth factors

Nonlinear Analysis of Pile Foundation Jacket Platform

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China ocean Engineering 1997年第1期12卷 21-28页

作者： xu, B Shen, zh Institute of Mechanics Chinese Academy of Sciences Beijing 100080 China

In this paper, the nonlinear collapse of the BoHAI-8 pile foundation jacket platform has been analyzed. The ultimate load and collapse process of two computational models of the structure are given. one model is of fixed support whose length is eight times the pile leg diameter and the other considers the nonlinearity of the soil-pile interaction.

关键词： nonlinear analysis jacket platform ultimate load platform collapse

Inhibitory activity of polysaccharide extracts from three kinds of edible fungi on proliferation of human hepatoma SMMC-7721 cell and mouse implanted S180 tumor

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World Journal of Gastroenterology 1999年第5期5卷 404-407页

作者： Jiang SM Xiao ZM xu zh Shandong Normal Univ Dept Biol Provincial Key Lab Anim Stress Jinan 250014 Shandong Prov Peoples R China Univ Heidelberg D-6900 Heidelberg Germany

AIM To determine the activities ofpolysaccharide extracts from Flammulina velutipes (Curt. ex Fr. ) Sing (FV), Lentinusedodes (LE) and Agaricus bisporus Sing (AB)on the proliferation of human hepatoma SMMC-7721 cells in vitro and on mouse implanted S-180tumors in *** The polysaccharide extracts were isolated from the fruit bodies of FV, LE and AB by the methods of hot-water extraction, Sevag’sremoval of proteins, ethanol precipitation,trypsin digestion and ethanol fractionalprecipitation. Human hepatoma SMMC-7721 cells were treated with 50 mg/L Polysaccharide extracts, and the mitosis index, mitochondria activity and cell proliferation were detected at different times in both control and experimental groups. The mice with S-180 implanted tumors were injected with the polysaccharide extracts at 24 mg/ kg body weight for 9 d and the tumorweight was measured on the 15th *** The mitosis index of hepatoma cells in vitro could be significantly decreased by treatment with the polysaccharide extracts fromthe three kinds of edible fungi (P ochondria activity of SMMC7721 cells treated with polysaccharide extracts were lower than those in control groups (P on rates of polysaccharide extracts against implanted S-180 tumors in mice were 52.8%, 56.6% and 51 .9% respectivelycompared with that in c0ntrol ***0N The PoIysaccharide extractsfrom the three kinds of edible fungi could inhibitnot only the Cultured malignant cells in vitfo butalso impIanted Sl80 tum0r i0 vivo.

关键词： polysaccharide, edible fungi liver neoplasm carcinoma, hepatocellular SMMC7721, tumor cell, cultured implanted tumor, S-180 cell proliferation

Structure dependence of intramolecular photoinduced electron transfer in 9-aminoacridine benzoyl esters dyads linked by a polyether chain

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Chinese Science Bulletin 1997年第19期42卷 1619-1624页

作者： Li, SL Tian, HJ zhou, QF Li, zh xu, HJ CHINESE ACAD SCI INST PHOTOG CHEMBEIJING 100101PEOPLES R CHINA

ELECTRoN transfer plays a crucial role in energy transformation of natural biological systemssuch as the photosynthetic process by which plants convert solar energy into chemical *** is achieved in photosynthesis by a series of electron transfers which occur after light is ab-sorbed. Among the various factors which influence the efficiency of electron transfer struc-tural effect is one of the important features to be considered. In recent years, numerous syn-thetic model dyads in which electron donor and electron acceptor are covalently linked by dif-ferent spacers have been designed and synthesized in an effort to understand how the

关键词： polyether donor-acceptor dyads intramnlecular photoinduced electron transfer.

Involvement of apoptosis of alveolar epithelial cells in acute pancreatitis-associated lung injury

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World Journal of Gastroenterology 2000年第6期6卷 920-924页

作者： Yuan YZ Gong zh Lou KX Tu SP zhai ZK xu JY Shanghai Med Univ 2 Ruijin Hosp Dept Gastroenterol Shanghai 200025 Peoples R China

INTRoDUCTIoNAcute pancreatitis in a common and potentially fataldisease which is associated with considerablemorbidity and a mortality rate of approximately30%;its pathogenesis remains *** of death is often due to mul... 详细信息

关键词： pancreatitis lung/injuries apoptosis protein P53 immunohistochemistry platelet activating factor