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人工智能在脊髓神经损伤与修复领域研究热点的可视化分析

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中国组织工程研究 2025年第4期29卷 761-770页

作者：杨彬陶广义杨顺许俊杰黄俊卿河南省中医院/河南中医药大学第二附属医院疼痛科河南省郑州市450000 河南中医药大学骨伤学院河南省郑州市450000

背景:近年来人工智能逐渐兴起,在多方面应用于脊髓神经损伤与修复领域,对临床治疗也有诸多积极影响。目的:研究人工智能在脊髓神经损伤与修复领域的诊断、治疗和康复中的应用进展,明确该领域的研究热点和不足,为今后研究工作提供建议。... 详细信息

背景:近年来人工智能逐渐兴起,在多方面应用于脊髓神经损伤与修复领域,对临床治疗也有诸多积极影响。目的:研究人工智能在脊髓神经损伤与修复领域的诊断、治疗和康复中的应用进展,明确该领域的研究热点和不足,为今后研究工作提供建议。方法:在Web of Science核心集数据库检索建库至2023年收录的人工智能在脊髓神经损伤与修复领域相关文献,使用CiteSpace 6.1.R6和VOSviewer 1.6.19软件对文献数据进行一般文献学分析、文献共被引、期刊共被引、期刊双图叠加及关键词聚类等可视化分析。结果与结论:①共筛选出1713篇文章,此领域年发文量呈波动上升趋势,其中美国占据主导地位,Kadone Hideki是发文量最多的作者,《ARCH PHYS MED REHAB》是被引用次数最多的期刊。②关键词共现和聚类分析显示,去除与检索词相近的关键词后,主要关键词被分为3个主要集群:外骨骼与运动康复(为最大核心热点)、机器学习和神经可塑性、机器人和康复训练。③关键词爆发分析显示,深度学习和人工智能在过去5年中已成为突发术语。④文献共被引和高被引文献分析结果显示,人工智能在脊髓神经损伤与修复领域热点集中于动力外骨骼(powered exoskeleton)、步态(gait)、神经电刺激(electrical nerve stimulation)、皮质内脑机接口(intracortical brain-computer interface,IBCI)、机器人(robot)、高分子生物材料(polymer biomaterials)及神经干细胞(neural stem cell)等内容。⑤人工智能在脊髓神经损伤与修复领域的研究近年来呈现上升趋势,该领域的关注点从外骨骼、电刺激等单一的治疗手段,逐渐向智能化、精准化和个性化等方向转变。⑥该领域存在一些局限性,例如数据缺失或不平衡的后果、数据准确性和可重复性低以及伦理问题(如隐私、研究透明度和临床可靠性等),未来的研究应该解决数据收集的问题,需要大样本、高质量的临床数据集来建立有效的人工智能模型;同时该领域的基因组学等机制研究十分薄弱,未来可利用类脑芯片等多种机器学习技术,运用基因编辑治疗及单细胞空间转录组等方法,进行再生相关基因上调和轴突生长结构蛋白产生等基础机制研究。

关键词：人工智能神经再生脊髓损伤机器外骨骼脑机接口神经电刺激脑皮质重组深度学习机器学习神经网络

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经典名方百合地黄汤的历史衍变及研究进展

吉林中医药 2024年第4期44卷 475-480页

作者：许俊洁刘佳徐娇雅郑新春上海中医药大学附属光华医院关节内科上海200050

百合地黄汤是《古代经典名方目录(第一批)》中收录方剂。通过整理古代医籍、现代文献,系统考证百合地黄汤处方来源、组方、主治等历史沿革及研究现状,发现该方最早见于汉代名医张仲景所著《金匮要略》,组方“少而精”,主治百合病,后世... 详细信息

百合地黄汤是《古代经典名方目录(第一批)》中收录方剂。通过整理古代医籍、现代文献,系统考证百合地黄汤处方来源、组方、主治等历史沿革及研究现状,发现该方最早见于汉代名医张仲景所著《金匮要略》,组方“少而精”,主治百合病,后世医籍记载主治与原方基本一致。处方剂量、药味炮制及煎服法均沿袭原方,鲜有改动。现代药理研究发现其具有抗抑郁、失眠、抗肿瘤等作用,主要用该经典名方治疗神经精神系统疾病,如抑郁症、焦虑症、睡眠障碍、心理亚健康状态等。通过全面文献考证,可为经典名方百合地黄汤的现代开发提供理论依据与文献参考。

关键词：百合地黄汤经典名方历史沿革药理作用临床应用

密度对稻壳/聚氯乙烯发泡复合材料尺寸稳定性及力学性能的影响

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木材科学与技术 2024年第3期38卷 56-63,77页

作者：邢志栋徐俊杰欧荣贤黄剑飞易欣郝笑龙华南农业大学生物基材料与能源教育部重点实验室广东广州510642 华南农业大学生物质工程研究院农业农村部能源植物资源与利用重点实验室广东广州510642 佛山市顺德区锡山家居科技有限公司广东佛山528300

针对传统木塑复合材料(wood plastic composites,WPCs)密度大、尺寸稳定性差等问题,以稻壳和聚氯乙烯(polyvinyl chloride,PVC)为原料制备三种密度的稻壳/聚氯乙烯发泡复合材料(rice husk/polyvinyl chloride foamed composites,RHPC),分别标记为RHPC-Ⅰ、RHPCⅡ、RHPC-Ⅲ,探究密度变化对RHPC性能的影响。结果显示:随着发泡程度的增加及密度的减小,RHPC的泡孔均匀程度有所降低。RHPC的线性热膨胀系数(coefficient of linear thermal expansion,CLTE)及吸水膨胀率均逐渐升高,且长度、宽度和厚度三个方向上的尺寸变化率均表现出各向异性;不同湿度和温度作用下的尺寸变化率表明湿度对RHPC尺寸的影响大于温度。RHPC-Ⅰ、RHPCⅡ、RHPC-Ⅲ的弯曲强度、弯曲模量和抗蠕变性能呈下降趋势;RHPC-Ⅱ由于均匀的泡孔结构呈现出最高的冲击强度和比冲击强度,分别为14.3 kJ/m2和19.9(k J·m^(-2))/(g·cm^(-3))。本研究为轻质高强WPCs的开发和拓宽其应用领域提供指导。

关键词：稻壳/聚氯乙烯发泡复合材料发泡力学性能尺寸稳定性蠕变

Chemical synthesis and coercivity enhancement of Nd2Fe14B nanostructures mediated by non-magnetic layer

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Nano Research 2020年第4期13卷 1141-1148页

作者： Kai Zhu junjie xu Xiaobai Wang Wei Li Kesong Tian Yanglong Hou Beijing Key Laboratory for Magnetoelectric Materials and Devices(BKLMMD) Beijing Innovation Centre for Engineering Science and Advanced TechnologyDepartment of Materials Science and EngineeringCollege of EngineeringPeking UniversityBeijing 100871China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China

High-performance Nd2Fei4B magnets have been widely required in various fields recently due to the lightweight and miniaturization of *** this work,we synthesize Nd2Fei4B nanostructures with tunable magnetic properties through surfactant-assisted high energy ball milling(SAHEBM)process,achieving prominently enhanced coercivity by forming non-magnetic layers as grain boundary *** the reduction annealing process was carried out as pellet with Ca,the coercivity increased from 0.8 kOe to over 3 kOe as Nd2Fei4B powder,which is proved to be the contribution of the chemical diffusion of Nd elements and the formation of Nd-rich layer as magnetic insulating *** addition,two-dimensional graphene oxide(GO)was employed to build extra grain boundary,by which the coercivity of the core@dual-shell structure can achieve up to 8 kOe,tenfold of the original *** intrinsic mechanism indicated that the Nd-diffusion induced Nd-rich phase along with the reduced GO in the system could form non-magnetic layer as grain boundary and magnetically isolate the adjacent grains,significantly enhancing the exchange coupling *** work markedly opens up an effective approach for the chemical preparation of high-performance Nd2Fe14B nanostructured magnets,especially after post treatment,and gives an insight on the interactions at nanoscale.

关键词： Nd2Fei4B nanostructures chemical reduction diffusion process grain boundary graphene oxide coercivity enchantment

Mechanism and Geo-mechanics Models of Landslides Triggered by 5.12 Wenchuan Earthquake

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Journal of Mountain Science 2011年第2期8卷 200-210页

作者： HUANG Runqiu xu Qiang HUO junjie State Key Laboratory of Geohazards Prevention and Geoenvironment Protection Chengdu University of Technology Chengdu Sichuan China

Due to the extremely high magnitude, long duration, and the complicated geo-environment in the disaster area, the great 5.12 Wenchuan Earthquake not only produced a huge number of landslides and rockfalls, but also involved complicated dynamic processes. These processes are quite different from the characteristics of landslides and rockfalls under general gravitational force, and presently human knowledge is very poor in this field. In order to describe the special dynamic processes, some terms such as shattering-cracking, shattering-sliding, shattering-falls and ejection are defined in this paper. Combined with slope structures, a mechanism classification system of strong earthquake-triggered landslide and rockfall is suggested, which is divided into 5 categories and 14 types. This paper also analyzes the basic characteristics, dynamic processes and geo-mechanics conceptual models of some typologies, especial the type of shattering-sliding for most large-scales landsides. This paper initially reveals the formation mechanism, geo-mechanics models and dynamic features of landslides and rockfalls triggered by the great Wenchuan Earthquake.

关键词： 5.12 Wenchuan Earthquake Landslide Rockfall Geo-mechanics model

关节外加强在前交叉韧带损伤治疗中的研究进展

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中国研究型医院 2024年第1期11卷 23-28页

作者：叶梓鹏徐俊杰赵金忠上海交通大学附属第六人民医院运动医学科上海200233

膝关节前交叉韧带(ACL)损伤的患者常合并前外侧结构(ALS)损伤或功能障碍,单独行ACL重建不足以恢复膝关节静态和动态旋转稳定性。针对ALS的组成结构,学者们设计出以外侧关节外肌腱固定、前外侧韧带重建和ALS重建为代表的关节外加强术式。... 详细信息

膝关节前交叉韧带(ACL)损伤的患者常合并前外侧结构(ALS)损伤或功能障碍,单独行ACL重建不足以恢复膝关节静态和动态旋转稳定性。针对ALS的组成结构,学者们设计出以外侧关节外肌腱固定、前外侧韧带重建和ALS重建为代表的关节外加强术式。ACL重建高失效风险患者联合关节外加强,有助于改善膝关节旋转不稳,降低临床失效率。本文作者就近年来关节外加强的手术指征、常用术式、静力学效应、运动学效应、临床效果及潜在风险等研究进行综述。

关键词：膝关节损伤前交叉韧带前外侧结构关节外加强旋转稳定性

农业全要素生产率空间格局演化、驱动因素及提升策略——以扬州市为例

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现代农业研究 2024年第9期30卷 32-35页

作者：徐俊杰余淼韩宏华扬州大学商学院江苏扬州225009

农业全要素生产率效率是衡量农业经济增长、农业生态环境保护与资源节约统筹发展的重要指标。文章基于扬州2008—2017年扬州的面板数据;采用超效率SBM模型就其农业全要素生产率展开了实证分析并在此基础上对其影响因素进行了剖析。结果... 详细信息

农业全要素生产率效率是衡量农业经济增长、农业生态环境保护与资源节约统筹发展的重要指标。文章基于扬州2008—2017年扬州的面板数据;采用超效率SBM模型就其农业全要素生产率展开了实证分析并在此基础上对其影响因素进行了剖析。结果表明:研究期间扬州市各乡镇农业全要素生产率空间上凸显个体差异性特征;影响因素分析发现不同区域对各要素的响应程度存在很大的差异性。

关键词：农业全要素生产率时空格局影响因素超效率SBM模型

Hierarchical magnetic core-shell nanostructures for microwave absorption:Synthesis,microstructure and property studies

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Science China Chemistry 2014年第1期57卷 3-12页

作者： LIU JiWei xu junjie LIU ZhengWang LIU XiaLin CHE RenChao Department of Materials Science and Laboratory of Advanced Materials Fudan University National Institute for Materials Science (NIMS) Sengen 1-2-1Tsukuba Ibaraki 305-0047 Japan

Core-shell nanostructures have attracted considerable attention in the past decades because of their fundamental scientific significance and many technological ***,it has been reported that the core-shell nanostructures with advanced compositions and complicated morphologies show great potential as high-performance microwave absorbers due to their unique properties,such as large surface areas,multi-functionalities and synergistic effects between the interior core and outer *** review article focuses on the recent progress in synthesis and characterization of hierarchical magnetic core-shell nanostructures for microwave absorption applications based on our own *** addition,several future trends in this field for next-generation microwave absorbers are discussed.

关键词： magnetite,core-shell,hierarchical,hydrothermal synthesis,microstructure,microwave absorption

Constraints on the Ediacaran-Cambrian boundary in deep-water realm in South China: Evidence from zircon CA-ID-TIMS U-Pb ages from the topmost Liuchapo Formation

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Science China Earth Sciences 2020年第8期63卷 1176-1187页

作者： Wei WANG Mingzhong ZHOU Zhuyin CHU junjie xu Chaofeng LI Taiyi LUO Jinghui GUO State Key Laboratory of Lithospheric Evolution Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029China University of Chinese Academy of Sciences Beijing 100049China Innovation Academy for Earth Science Chinese Academy of SciencesBeijing 100029China School of Geographical and Environmental Sciences Guizhou Normal UniversityGuiyang 550001China:China University of GeosciencesBeijing 100083China:State Key Laboratory of Ore Deposit GeochemistryInstitute of GeochemistryChinese Academy of SciencesGuiyang 550002China

The placement of the Ediacaran-Cambrian boundary in deep-water realm in South China and the high-precision temporal framework for the Ediacaran-Cambrian transition in this region have not yet been completely solved. Recently, we have found two K-bentonite beds in the top of the Liuchapo Formation at the Pingyin section, Guizhou Province. It provides an opportunity for constructing the temporal framework of the transitional strata on the Yangtze Platform in South China and for determining the Ediacaran-Cambrian boundary in this area. In this study, we conducted high-precision CA-ID-TIMS U-Pb dating on zircons from the two K-bentonites. The ages of the two K-bentonites were precisely constrained at 536.40±0.47/1.1/1.2 Ma(2σ, n=7, MSWD=0.92) and 541.48±0.46/1.1/1.2 Ma(2σ, n=8, MSWD=1.3). Combining the geochronological results with organic carbon isotope data of chert in the topmost Liuchapo Formation from the section, we suggest that the EdiacaranCambrian boundary should be consistent with a significant negative organic carbon isotope excursion between the two Kbentonites. The scheme of the Ediacaran-Cambrian boundary in this study is of great significance for global correlation, and further for unravelling the information of the terminal Ediacaran-early Cambrian ocean.

关键词： Liuchapo Formation Yangtze Platform Ediacaran-Cambrian CA-ID-TIMS Organic carbon isotope