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Journal of Materials Science & Technology 2024年第3期170卷 200-211页

作者： Yanyan Zhao xu fan Hongxing Zheng Enzhou Liu Jun fan xuejun Wang College of Biology Pharmacy and Food Engineering Shangluo UniversityShangluo 726000China QinLing-Bashan Mountains Bioresources Comprehensive Development C.I.C. Shaanxi University of TechnologyHanzhong 723001China School of Chemical Engineering Northwest UniversityXi’an 710069China

Constructing of heterojunction was identified as a feasible way to improve photocatalytic activity of *** this work,a n-p type Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction was successfully prepared for organic pollutants *** Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction exhibited much higher pho-tocatalytic activity towards Rhodamine B(92.24%,expose to visible light for 60 min),norfloxacin(81.73%,expose to visible light for 90 min)and levofloxacin(87.46%,expose to visible light for 90 min)than pure Bi_(2)WO_(6)and pure AgInS_(2).Toxicity analysis indicated the low environmental toxicity of Rhodamine B degradation intermediates for Rye seeds and Sudangrass seeds germination and *** study displayed that AgInS_(2)and Bi_(2)WO_(6)work as the primary photocatalyst to form·O_(2)−and ·OH,*** improved photocatalytic activity of the Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction was due to the im-proved light response range and intensified carrier separation ***,a S-scheme charge transfer mechanism including multiple charge transfer channels was *** work could provide an effective strategy for organic pollutants degradation in wastewater.

关键词： Photocatalysis S-scheme heterojunction AgInS_(2) Bi_(2)WO_(6) Toxicity experiments

Polycomb and trithorax:Their yin-yang dynamics in plants

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Molecular Plant 2024年第6期17卷 845-847页

作者： fan xu Daolei Zhang Liang Le Li Pu Biotechnology Research Institute Chinese Academy of Agricultural SciencesBeijing 100081China School of Life Science Inner Mongolia UniversityHohhot 010021China

Polycomb(PcG)and trithorax(trxG)are two groups of conserved epigenetic complexes that maintain active and repressive states of target genes by altering their chromatin states to regulate plant development and stress *... 详细信息

关键词： maintain complexes states

Phase separation of GRP7 facilitated by FERONIAmediated phosphorylation inhibits mRNA translation to modulate plant temperature resilience

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Molecular Plant 2024年第3期17卷 460-477页

作者： fan xu Long Wang Yingbin Li Junfeng Shi Dorothee Staiger Feng Yu state Key Laboratory of Chemo/Biosensing and Chemometrics College of Biologyand Hunan Key Laboratory of Plant Functional Genomics and Developmental RegulationHunanUniversityChangsha 410082P.R.China State Key Laboratory of Hybrid Rice Hunan Agricultural Biotechnology Research InstituteHunan Academy of Agricultural SciencesChangsha 410125P.R.China RNA Biology and Molecular Physiology Faculty of BiologyBielefeld University33615 BielefeldGermany

Changes in ambient temperature profoundly affect plant growth and ***,the molecu-larbasis of plant acclimation to temperature fluctuation is of great *** this study,we discovered that GLYCINE-RICH RNA-BINDING PROTEIN 7(GRP7)contributes to cold and heat tolerance in Arabidopsis *** found that exposure to a warm temperature rapidly induces GRP7 condensates in planta,which can be reversed by transfer to a lower *** biology and biochemical assays revealed that GRP7 undergoes liquid-liquid phase separation(LLPS)in vivo and in *** of GRP7 in the cyto-plasm contributes to the formation of stress granules that recruit RNA,along with the translation machinery component eukaryotic initiation factor 4E1(elF4E1)and the mRNA chaperones COLD SHOCK PROTEIN 1(CSP1)and CSP3,to inhibit ***,natural variations in GRP7 affecting the residue phos-phorylated by the receptorkinase FERONIA alter its capacity to undergo LLPS and correlate with the adap-tation of some Arabidopsis accessions to a widertemperature *** together,ourfindings illustrate the role of translational control mediated by GRP7 LLPS to confer plants with temperature resilience.

关键词： fluctuating temperature glycine-rich RNA-binding protein phase separation cold shock proteins translation

Equilibrium Joining Strategies of Retrial Queueing Systems with Two-phase Service and Priority-purchasing

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Acta Mathematicae Applicatae Sinica 2024年

作者： fan xu Rui-ling TIAN Qi SHAO School of Science Yanshan University

This paper considers the customer’s equilibrium joining-balking behavior in a retrial queue with two-phase service and priority-purchasing. If the arriving customer finds the server busy, the customer can make three choices (joining the orbit, purchasing the priority or balking) based on different levels of the system information. We consider two cases:the partially observable case and the fully unobservable case. The customer’s equilibrium strategy for the partially observable case and the fully unobservable case are derived. Then, an algorithm is developed to solve the optimal fee that maximizes the service provider’s profit. Finally, the influence of system parameters on performance measures, equilibrium joining strategies and the service provider’s profits is illustrated by numerical examples.

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Numerical investigation on thermomechanical behavior of alumina–calcium hexaluminate refractories for purging plug

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Journal of Iron and Steel Research International 2024年第2期31卷 389-400页

作者： Li-ping Pan Ya-wei Li fang-guan Tan Yi-chen Chen Yang-fan xu Zhu He Bao-kuan Li The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan430081HubeiChina National-Provincial Joint Engineering Research Center of High Temperature Materials and Lining Technology Wuhan University of Science and TechnologyWuhan430081HubeiChina

Alumina–spinel refractories used in slit-type purging plugs are susceptible to cross-sectional damage,resulting in a serious mismatch between their service life and that of ***–calcium hexaluminate refractories have gradually become the new trend in purging plug materials with the development of refining *** thermomechanical damage of slit-type purging plugs with alumina–calcium hexaluminate refractory was investigated by the thermo-solid coupling *** with the polynomial fitting and design of experiments methods,the influence of thermophysical parameters on temperature and thermal stress of alumina–calcium hexaluminate refractories for purging plugs was systematically *** results show that the maximum thermal stress of the purging plugs appears during the stages of steel transporting and stirring,and the vulnerable parts are located above Y=0.323 *** thermal conductivity and the coefficient of thermal expansion of the material are the most sensitive parameters to the temperature and thermal stress inside the structure,*** addition of more calcium hexaluminate can relieve the stress concentration and large deformation around the ***,when the content of calcium hexaluminate is 47 wt.%and in the form of aggregate-binder,the temperature and thermal stress distribution inside the refractory are optimal,which can effectively improve the service life of the slit-type purging plug.

关键词： Purging plug Thermomechanical damage Refractory Design of experiments method Stress

A robust indium-organic framework with open tubular channels for efficient separation of acetylene

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Nano Research 2024年第4期17卷 3139-3146页

作者： Yong-Zhi Li Gang-Ding Wang fan xu Qing Yin Danyang Zhao Jiqiu Qi Yanwei Sui Lei Hou Yao-Yu Wang School of Materials and Physics China University of Mining and TechnologyXuzhou 221116China Key Laboratory of Synthetic and Natural Functional Molecule of the Ministry of Education Shaanxi Key Laboratory of Physico-Inorganic ChemistryCollege of Chemistry&Materials ScienceNorthwest UniversityXi’an 710069China

Considering the tremendous applications and purification requirement of acetylene(C_(2)H_(2)),seeking appropriate adsorbents with high capacity and selectivity is a vital task and remains an enduring ***,we designed and synthesized a robust three-dimensional(3D)indium-organic framework([(Me)_(2)NH_(2)][In(L6)_(0.5)(IPA)_(0.5)]·DMA·2H_(2)O(In-L6-IPA,DMA=dimethylammonium,IPA=isopropyl alcohol))featuring two types of one-dimensional(1D)tubular *** activated In-L6-IPA displayed high loading for C_(2)H_(2)(104.4 cm^(3)·g^(-1),the second highest value among all reported indium-based metal-organic frameworks(MOFs))and simultaneously selective adsorption for C_(2)H_(2) over CO_(2),C_(2)H_(6),and ethylene(C_(2)H_(4))at 298 K under 100 *** modelling revealed that the porous wall of In-L6-IPA provides more and stronger multiple interactions for C_(2)H_(2) than CO_(2),C_(2)H_(6),and C_(2)H_(4) containing C–H···π,C–H···O,and O···π*** experiments validated the actual separation ability for various ratios of binary C_(2)H_(2)/C_(2)H_(4) and C_(2)H_(2)/CO_(2) mixtures as well as equimolar ternary C_(2)H_(2)/C_(2)H_(4)/CO_(2) and C_(2)H_(2)/C_(2)H_(4)/C_(2)H_(6) mixtures with excellent reusability.

关键词： indium-organic framework crystal structure gas adsorption acetylene(C_(2)H_(2))separation

EjGASA6 promotes flowering and root elongation by enhancing gibberellin biosynthesis

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Journal of Integrative Agriculture 2024年第5期23卷 1568-1579页

作者： Qian Chen Shunyuan Yong fan xu Hao Fu Jiangbo Dang Qiao He Danlong Jing Di Wu Guolu Liang Qigao Guo Key Laboratory of Agricultural Biosafety and Green Production of Upper Yangtze River(Ministry of Education)/College of Horticulture and Landscape Architecture Southwest UniversityChongqing 400715China State Cultivation Base of Crop Stress Biology for Southern Mountainous Land of Southwest University/Academy of Agricultural Sciences of Southwest University Chongqing 400715China College of Agronomy and Biotechnology Southwest UniversityChongqing 400715China

The Gibberellic Acid-stimulated Arabidopsis(GASA)gene family is involved in the regulation of gene expression and plant growth,development,and stress *** investigate the function of loquat GASA genes in the growth and developmental regulation of plants,a loquat EjGASA6 gene homologous to Arabidopsis AtGASA6 was ***6 expression was induced by gibberellin,and ectopic transgenic plants containing this gene exhibited earlier bloom and longer primary roots since these phenotypic characteristics are related to higher gibberellin *** analysis and qRT-PCR results showed that the expression levels of GA3ox1 and GA20ox1,which encode key enzymes in gibberellin biosynthesis,were significantly ***,we confirmed that EjGASA6 could promote the expression of GA20ox1 via the luciferase reporter ***,our results suggest that EjGASA6 promotes blooming and main-root elongation by positively regulating gibberellin *** findings broaden our understanding of the role of GASAs in plant development and growth,and lay the groundwork for future research into the functions of EjGASA6 in regulating loquat growth and development.

关键词： loquat EjGASA6 gibberellin synthesis biological function

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VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling

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World Journal of Stem Cells 2024年第2期16卷 207-227页

作者： Yun Yuan xu-fan Zhang Yu-Chen Li Hong-Qing Chen Tian Wen Jia-Lian Zheng Zi-Yi Zhao Qiong-Ying Hu Department of Laboratory Medicine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Nuclear Medicine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina College of Medical Technology Chengdu University of Traditional Chinese MedicineChengdu 611137Sichuan ProvinceChina Department of Hepatology Affiliated Hospital of Liaoning University of Traditional Chinese MedicineShenyang 110032Liaoning ProvinceChina Hospital of Chengdu University of Traditional Chinese Medicine Chengdu 610072Sichuan ProvinceChina Traditional Chinese Medicine Regulating Metabolic Diseases Key Laboratory of Sichuan Province Chengdu 610072Sichuan ProvinceChina

BACKGROUND Colorectal cancer stem cells(CCSCs)are heterogeneous cells that can self-renew and undergo multidirectional differentiation in colorectal cancer(CRC)*** are generally accepted to be important sources of CRC and are responsible for the progression,metastasis,and therapeutic resistance of ***,targeting this specific subpopulation has been recognized as a promising strategy for overcoming *** To investigate the effect of VX-509 on CCSCs and elucidate the underlying *** CCSCs were enriched from CRC cell lines by in conditioned serum-free *** blot,Aldefluor,transwell and tumorigenesis assays were performed to verify the phenotypic characteristics of the *** anticancer efficacy of VX-509 was assessed in HCT116 CCSCs and HT29 CCSCs by performing cell viability analysis,colony formation,sphere formation,flow cytometry,and western blotting assessments in vitro and tumor growth,immunohistochemistry and immunofluorescence assessments in *** Compared with parental cells,sphere cells derived from HCT116 and HT29 cells presented increased expression of stem cell transcription factors and stem cell markers and were more potent at promoting migration and tumori-genesis,demonstrating that the CRC sphere cells displayed CSC ***-509 inhibited the tumor malignant biological behavior of CRC-stem-like cells,as indicated by their proliferation,migration and clonality in vitro,and suppressed the tumor of CCSC-derived xenograft tumors in ***,VX-509 suppressed the CSC character-istics of CRC-stem-like cells and inhibited the progression of epithelial-mesenchymal transition(EMT)signaling in *** was identified as the regulatory factor of VX-509 on CRC stem-like cells through analyses of differen-tially expressed genes and CSC-related database ***-509 markedly downregulated the expression of Nodal and its downstream phosphorylated Smad2/3 to inhibit EMT ***,VX-509 rev

关键词： Colorectal cancer stem cells Stemness VX-509 Epithelial-mesenchymal transition Nodal

天竺地理观念在中土的传播与接受--以“佛教圣山河源说”为例

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中国历史地理论丛 2024年第2期39卷 67-79页

作者：徐帆复旦大学历史地理研究中心上海200433

因地理视野不同,佛教“阿耨达池(山)河流发源体系”存在四河、五河与八河之分异。东汉末年,“四河说”开始与中国本土的“昆仑河流发源体系”相融合。十六国时期,道安将“四河”演绎为“六大水”。唐宋时期,僧俗两界分别从不同侧面对“... 详细信息

因地理视野不同,佛教“阿耨达池(山)河流发源体系”存在四河、五河与八河之分异。东汉末年,“四河说”开始与中国本土的“昆仑河流发源体系”相融合。十六国时期,道安将“四河”演绎为“六大水”。唐宋时期,僧俗两界分别从不同侧面对“佛教圣山河源说”进行了阐释,其中道宣因推崇“天竺中心观”而尤其倡导此说。此后,元代都实的探源之举动摇了“河出昆仑说”和“佛教圣山河源说”的地理基础,清康熙时期的地理实践进一步使河源与“佛教圣山”相分离,但乾隆以后,“佛教圣山河源说”在知识界仍有着不容小觑的影响力。这一历史认知现象表明,在现代地理学兴起以前,宗教地理学说是古人认识世界的一个重要参考。

关键词：黄河源阿耨达池(山) 昆仑佛教地理认知

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1例病情进展迅速的重症肺炎的诊治体会

复旦学报（医学版） 2024年第3期51卷 415-419页

作者：徐帆朱蕾北京大学人民医院重症医学科北京100044 复旦大学附属华东医院呼吸与危重医学科上海200040

新冠病毒感染常态化管理后,不同病原体感染所致重症肺炎的发病率较高,由于病情进展迅速或短期难以获得病原学依据,导致部分患者较难选择有效的针对性药物。临床常给予多种抗感染药物,联合糖皮质激素抗炎、丙种球蛋白等提高免疫功能的“... 详细信息

新冠病毒感染常态化管理后,不同病原体感染所致重症肺炎的发病率较高,由于病情进展迅速或短期难以获得病原学依据,导致部分患者较难选择有效的针对性药物。临床常给予多种抗感染药物,联合糖皮质激素抗炎、丙种球蛋白等提高免疫功能的“广覆盖治疗”及呼吸支持治疗,但死亡率较高。复旦大学附属华东医院近期收治1例基础情况好的青年非重症社区获得性肺炎(community-acquired pneumonia,CAP)患者,入院后患者病情迅速加重,十余小时后演变为重度急性呼吸窘迫综合征,且淋巴细胞下降,采用前述“广覆盖治疗”无效,经合理的生理学和生物学分析,迅速调整为以短期大剂量激素和分级无创呼吸支持为主的综合治疗,患者病情迅速好转,淋巴细胞短暂下降后迅速恢复,未出现其他明显不良反应,10日后痊愈出院。该例患者的诊治经验可为CAP的诊治提供参考。

关键词：社区获得性肺炎(CAP) 急性呼吸窘迫综合征(ARDS) 生理学分析炎症指标糖皮质激素

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