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Chinese Chemical Letters 1998年第7期9卷 671-674页

作者： Zhu, JH xu, qh Nanjing Univ Dept Chem Nanjing 210093 Peoples R China

Toluene pretreatment caused many activated toluene species existing on the surface of zeolite HZSM-5, by which the activity of sample was increased. Moreover, variation in the surface Si+/Al+ ratio of HZSM-5 was sensi... 详细信息

关键词： zeolite HZSM-5 surface state FABMS toluene ethylation

Synthesis and characterization of La-containing SiMCM-41

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Chinese Science Bulletin 1997年第7期42卷 560-563页

作者： He, NY Bao, SL xu, qh NANJING UNIV DEPT CHEMNANJING 210093PEOPLES R CHINA

FOR the reactions of larger molecules, the preparation of zeolites with large pore size has been a very important subject in zeolite chemistry. The mesoporous molecular sieves designated MCM-41 with pore size in the r... 详细信息

关键词： La-containing SiMCM-41 synthesis characterization hydrothermal stability.

Expression and significant roles of the long non-coding RNA CASC19/miR-491-5p/HMGA2 axis in the development of gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第8期16卷 3559-3584页

作者： Li-Xiang Zhang Pan-Quan Luo Zhi-Jian Wei A-Man xu Tao Guo Department of Gastroenterology The First Affiliated Hospital of Anhui Medical UniversityHefei 230031Anhui ProvinceChina Anhui Provincial Key Laboratory of Digestive Disease Hefei 230031Anhui ProvinceChina Department of General Surgery The First Affiliated Hospital of Anhui Medical UniversityHefei 230031Anhui ProvinceChina Anhui Public Health Clinical Center Hefei 230000Anhui ProvinceChina

BACKGROUND Gastric cancer(GC)is a common malignant tumor,long non-coding RNA and microRNA(miRNA)are important regulators that affect tumor proliferation,metastasis and chemotherapy resistance,and thus participate in tumor ***19 is a new bio-marker which can promote tumor invasion and ***,the mechanism by which CASC19 affects the progression of GC through miRNA is not *** To explore the role of the CASC19/miR-491-5p/HMGA2 regulatory axis in *** To explore the expression and prognosis of CASC19 in GC through clinical samples,and investigate the effects of inhibiting CASC19 on the proliferation,migration,invasion and other functions of GC cells through cell counting Kit-8(CCK-8),ethynyldeoxyuridine,Wound healing assay,Transwell,Western blot and flow cytometry *** effect of miR-491-5p and HMGA2 in GC were also *** regulatory relationship between CASC19 and miR-491-5p,miR-491-5p and HMGA2 were validated through Dual-luciferase reporter gene assay and reverse transcription *** CCK-8,Transwell,Wound healing assay,flow cytometry and animal experiments verify the role of CASC19/miR-491-5p/HMGA2 regulatory *** The expression level of CASC19 is related to the T stage,N stage,and tumor size of *** of the expression of CASC19 can inhibit the ability of proliferation,migration,invasion and EMT conversion of GC cells,and knocking down the expression of CASC19 can promote the apoptosis of GC *** the expression of miR-491-5p can inhibit the proliferation of GC cells,miR-491-5p mimics can inhibit EMT conversion,and promote the apoptosis of GC cells,while decreasing the expression of miR-491-5p can promote the proliferation and EMT conversion and inhibit the apoptosis of GC *** expression of HMGA2 in GC tissues is higher than that in adjacent *** the same time,the expression level of HMGA2 is related to the N and T stages of the *** the level of HMGA2 can pr

关键词： Gastric cancer Long non-coding RNA CASC19 miR-491-5p HMGA2 Prognosis

Importance of periphytic biofilms for carbon cycling in paddy fields:A review

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Pedosphere 2024年第1期34卷 36-43页

作者： Lei ZHOU Yonghong WU Junzhuo LIU Pengfei SUN Ying xu Jan DOLFING Robert GMSPENCER Erik JEPPESEN State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil ScienceChinese Academy of SciencesNanjing 210008China Zigui Three Gorges Reservoir Ecosystem Observation and Research Station of Ministry of Water Resources of the People's Republic of ChinaYichang 443605China College of Nanjing University of Chinese Academy of SciencesNanjing 211135China Faculty of Energy and Environment Northumbria UniversityNewcastle upon Tyne NE18QHUK Department of Earth Ocean and Atmospheric ScienceFlorida State UniversityTallahassee FL 32306USA Department of Ecoscience&Centre for Water Technology(WATEC) Aarhus UniversityAarhus DK-8000Denmark Sino-Danish Centre for Education and Research Beijing 100049China Limnology Laboratory Department of Biological Sciences and Centre for Ecosystem Research and Implementation(EKOSAM)Middle East Technical UniversityAnkara 06800Turkiye Institute of Marine Sciences Middle East Technical UniversityMersin 33731Turkiye

Paddy fields play an important role in global carbon(C) cycling and are an important source of methane(CH_(4)) emissions. Insights into the processes influencing the dynamics of soil organic C(SOC) in paddy fields are essential for maintaining global soil C stocks and mitigating climate change. Periphytic biofilms composed of microalgae, bacteria, and other microorganisms are ubiquitous in paddy fields, where they directly mediate the transfer of elements at the soil-water interface. However, their contributions to C turnover and exchange have been largely neglected. Periphytic biofilms affect and participate in soil C dynamics by altering both abiotic(e.g., pH and redox potential) and biotic conditions(e.g., microbial community composition and metabolism). This review summarizes the contributions of periphytic biofilms to soil C cycling processes, including carbon dioxide fixation, SOC mineralization, and CH_(4) emissions. Future research should be focused on: i) the mechanisms underlying periphytic biofilm-induced C fixation and turnover and ii) quantifying the contributions of periphytic biofilms to soil C uptake, stabilization, and sequestration in paddy fields.

关键词： carbon fixation carbon mineralization carbon sequestration methane emission microbial aggregates soil organic carbon

Clinicopathologic study of primary intestinal B cell malignantlymphoma

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World Journal of Gastroenterology 1999年第6期5卷 538-540页

作者： Zhou Q xu TR Fan qh Zhen ZX Nanjing Med Univ Affiliated Hosp 1 Dept Pathol Nanjing 210029 Jiangsu Prov Peoples R China

INTRODUCTIONPrimary intestinal B cell lymphoma is one of the most common extra-nodal lymphomas, which includes two types: intestinal mucosa-associated lymphoid tissue lymphoma (IMALToma) and lymphomatous polyposis (LP). Both have characteristic pathologic features, immunophen-otypes and biological behaviors. In this article, twenty-five cases were retrospectively analyzed with regard to criteria of diagnosis and clinicopathologic characteristics.

关键词： lymphoma/pathology intestinal neoplasms/pathology intestinal neoplasms/diagnosis

Tumor-associated telocytes

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Chinese Medical Journal 2024年第4期137卷 490-492页

作者： Jinqing Zhang Ying xu Department of General Surgery Shandong Provincial Third HospitalShandong UniversityJinanShandong 250117China

To the Editor:It has been eighteen years since telocytes(TCs)were first categorized by Popescu et al^([1])in *** were classified into interstitial cells of the Cajal(ICC)type based on their ultrastructure and immunohistochemical features,which are similar to mesenchymal cells.^([2])In the following ten years,TCs were found to have their own distinctive characteristics in terms of three-dimensional structure,immunological biomarkers,genomics,and multiple ***,TCs are definitely distinct from fibroblasts,mesenchymal stem cells,and endothelial cells in multiple organs of human beings and animals.^([3])

关键词： cytes organs definitely

Wave-Current Propagation over a Frictional Topography

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China Ocean Engineering 1998年第4期13卷 417-426页

作者： Zuo, qh Ding, BC Nanjing Hydraul Res Inst River & Harbour Dept Nanjing 210024 Peoples R China

In this paper the parabolic approximation model based on mild-slope equation is used to study wave propagation over a slowly varying and frictional topography under wave-current interaction. A governing equation considering the friction effects is derived by the authors for the first time. A simplified form for the rate of wave energy dissipation is presented on the basis of the wave-current action conservation equation and the bottom friction model given by Yoo and O'connor (1987). Examples reveal that the present computational method can be used for the calculation of wave elements for actual engineering projects with large water areas.

关键词： wave-current frictional topography refraction-diffraction

CALCULATION OF PENALTIES IN ALGORITHM OF MIXEDINTEGER PROGRAMMING SOLVING WITH REVISED DUALSIMPLEX METHOD FOR BOUNDED VARIABLES

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Journal of Computational Mathematics 1999年第5期17卷 545-552页

作者： Wei, YM Hu, qh Chinese Acad Sci Inst Policy & Management Beijing 100080 Peoples R China Wuhan Inst Chem Technol Wuhan 430073 Peoples R China

The branch-and-bound method with the revised dual simplex for bounded variables is very effective in solving relatively large-size integer linear programming problems. This paper, based on the general forms of the penalties by Beale and Small and the stronger penalties by Tomlin, describes the modifications of these penalties used for the method of bounded variables. The same examples from Petersen are taken and the satisfactory results are shown in comparison with those obtained by Tomlin.

关键词： penalties stronger penalties the revised dual simplex method for bounded variables

Crystal Structure of 5 ( l Menthyloxy) 3 Chloro 4 Pyrrolidinyl 2(5H) Furanone

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Chinese Journal of Structural Chemistry 1999年第2期18卷 35-38页

作者： Geng, Z Chen, qh Capital Normal Univ Dept Chem Beijing 100037 Peoples R China Beijing Normal Univ Dept Chem Beijing 100875 Peoples R China

The molecular structure of the title compound 5 ( l menthyloxy) 3 chloro 4 pyrrolidinyl 2(5H) furanone, C 18 H 28 ClNO 3(Ⅰ), has been determined by X ray diffraction at 296(1)K. The crystal is monoclinic with space group P2 1, a=9 457(3), b=10.413(3), c=9.525(2) , β=95.19(2)°, V=934(1)  3, Z=2, M r=341.88, D x =1.22 g/cm 3, μ =2.15 cm -1 , F(000)=368. The final R factor is 0 059, and R w is 0.065 for 1020 observed reflections with I≥3σ(I) . The absolute configuration at C(14) of the acetal carbon was proved to be S , taking into account the known configuration of 1R, 2S, 5R menthyl moiety. There are three rings in the molecule of this compound: the furanone ring, the pyrrolidine ring and the mentholoxy group ring. The franone ring is connected with the pyrrolidine ring and the mentholoxy ring by N atom and μ 2 O bridge atom respectively.

关键词： crystal structure absolute configuration Michael addition elimination reaction

Decoding m^(6)A mRNA methylation by reader proteins in liver diseases

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Genes & Diseases 2024年第2期11卷 711-726页

作者： Lijiao Sun Xin Chen Sai Zhu Jianan Wang Shaoxi Diao Jinyu Liu Jinjin xu Xiaofeng Li Yingyin Sun Cheng Huang Xiaoming Meng Xiongwen Lv Jun Li Inflammation and Immune Mediated Diseases Laboratory of Anhui Province Anhui Institute of Innovative DrugsSchool of PharmacyAnhui Medical UniversityHefeiAnhui 230032China The Key Laboratory of Anti-inflammatory and Immune Medicines Anhui Medical UniversityMinistry of EducationHefeiAnhui 230032China Institute for Liver Diseases of Anhui Medical University ILD-AMUAnhui Medical UniversityHefeiAnhui 230032China Department of Nephropathy The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230022China Department of Oncology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui 230032China

N6-methyladenosine(m^(6)A)is a dynamic and reversible epigenetic *** the most prevalent internal post-transcriptional modification in eukaryotic RNA,it participates in the regulation of gene expression through various mechanisms,such as mRNA splicing,nuclear export,localization,translation efficiency,mRNA stability,and structural *** involvement of m^(6)A in the regulation of gene expression depends on the specific recognition of m^(6)A-modified RNA by reader *** the pathogenesis and treatment of liver disease,studies have found that the expression levels of key genes that promote or inhibit the development of liver disease are regulated by m^(6)A modification,in which abnormal expression of reader proteins determines the fate of these gene *** this review,we introduce m^(6)A readers,summarize the recognition and regulatory mechanisms of m^(6)A readers on mRNA,and focus on the biological functions and mechanisms of m^(6)A readers in liver cancer,viral hepatitis,non-alcoholic fatty liver disease(NAFLD),hepatic fibrosis(HF),acute liver injury(ALI),and other liver *** information is expected to be of high value to researchers deciphering the links between m^(6)A readers and human liver diseases.

关键词： IGF2BPs Liver diseases m^(6)A modification m^(6)A reader mRNA metabolism YTH domain protein