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Risk factors of mortality and severe disability in the patients with cerebrovascular diseases treated with perioperative mechanical ventilation

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World Journal of Clinical Cases 2022年第16期10卷 5230-5240页

作者： Jin-Zhu Zhang Hao Chen Xin Wang kan xu Department of Neurosurgery The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND The prognosis of cerebrovascular diseases treated with mechanical ventilation during perioperative has not been clearly *** To analyze mortality and functional disability and to determine predictors of unfavorable outcome in the patients with cerebrovascular diseases treated with mechanical *** A retrospective follow-up study of 111 cerebrovascular disease patients who underwent mechanical ventilation during the perioperative period in the First Hospital of Jilin University from June 2016 to June 2019 was *** measurements were mortality and functional outcome in-hospital and after 3-month *** to the modified rankin scale(mRS),the functional outcome was divided into three groups:Good recovery(mRS≤3),severe disability(mRS=4 or 5)and death(mRS=6).Univariate analysis was used to compare the differences between three functional *** logistic regression analysis was used to for risk factors of mortality and severe *** The average age of 111 patients was 56.46±12.53 years,59(53.15%)were *** mortality of in-hospital and 3-month follow-up were 36.9% and 45.0%,*** 71 discharged patients,46.47% were seriously disabled and 12.67% died after three months *** analysis showed that preoperative glasgow coma scale,operation start time and ventilation reasons had statistically significant differences in different functional *** logistic regression analysis showed that the cause of ventilation was related to the death and poor prognosis of patients with cerebrovascular *** with brainstem compression,the risk of death or severe disability of pulmonary disease,status epilepticus,impaired respiratory center function,and shock were 0.096(95%CI:0.028-0.328),0.026(95%CI:0.004-0.163),0.095(95%CI:0.013-0.709),0.095(95%CI:0.020-0.444),*** The survival rate and prognostic outcomes of patients with cerebrovascular diseas

关键词： Cerebrovascular diseases Mechanical ventilation Perioperative Mortality Functional outcome

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Regenerative material for aneurysm embolizationA 3-dimensional culture system of fibroblasts and calcium alginate gel

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Neural Regeneration Research 2011年第10期6卷 762-766页

作者： Jingdong Zhang kan xu Jinlu Yu Jun Wang Qi Luo Department of Neurosurgery First Hospital of Jilin University Changchun 130021 Jilin Province China

Calcium alginate gel（CAG） has been shown to successfully model aneurysm embolization within a short period of ***,gradually degrading CAG potentially results in aneurysm *** the present study,a regenerative embolic material was designed by seeding rat fibroblasts in a *** study investigated the feasibility of constructing a 3-dimensional culture *** fibroblasts grew well and firmly attached to the *** was conducive for fibroblast growth,and resulted in a 3-dimensional culture *** show that CAG can be used theoretically as a vascular,regenerative,embolic material.

关键词： intracranial aneurysm embolic material detachable coil fibroblast alginate neural regeneration

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Probing the Non-equilibration Component of Tilting Spin Mode

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Chinese journal of nuclear physics 1994年第2期16卷 108-111页

作者： Liu, Zuhua Zhang, Huanqiao xu, Jincheng Qian, XIng Qiao, Yu Lin, Chengjian xu, kan China Inst of Atomic Energy Beijing China

-The probabilities PNCNE of non-equilibration component of tilting spinmode have been extracted from the experimental fragment anisotropies for thesystems of 16O+232Th,19F+232Th,and 16O+238*** is found that as a function ofBf（〈L〉）/Tsad,the values of PNCNF observed experimentally and expected on the ba-sis of fission before equilibration model have opposite trends.

关键词： Fission Tilting spin mode Non-equilibration

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A Weak Convergence Theorem for A Finite Family of Asymptotically Nonexpansive Mappings

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Communications in Mathematical Research 2014年第4期30卷 295-300页

作者： kan xu-zhou Guo Wei-ping School of Mathematics and Physics Suzhou University of Science and Technology

The purpose of this paper is to prove a new weak convergence theorem for a finite family of asymptotically nonexpansive mappings in uniformly convex Banach space.

关键词： asymptotically nonexpansive mapping weak convergence common fixed point uniformly convex Banach space

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Spinal cord decompression reduces rat neural cell apoptosis secondary to spinal cord injury

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2009年第3期10卷 180-187页

作者： kan xu Qi-xin CHEN Fang-cai LI Wei-shan CHEN Min LIN Qiong-hua WU Department of Orthopaedic Surgery Hangzhou 310009 China Department of Pathology the Second Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 China

Objective： To determine whether spinal cord decompression plays a role in neural cell apoptosis after spinal cord injury. Study design： We used an animal model of compressive spinal cord injury with incomplete paraparesis to evaluate neural cell apoptosis after decompression. Apoptosis and cellular damage were assessed by staining with terminal deoxynucleotidyl transferase （TdT）-mediated deoxyuridine triphosphate nick-end labelling （TUNEL） and immunostaining for caspase-3, Bcl-2 and Bax. Methods： Experiments were conducted in male Sprague-Dawley rats （n-78） weighing 300-400 g. The spinal cord was compressed posteriorly at T10 level using a custom-made screw for 6 h, 24 h or continuously, followed by decompression by removal of the screw. The rats were sacrificed on Day I or 3 or in Week 1 or 4 post-decompression. The spinal cord was removed en bloc and examined at lesion site, rostral site and caudal site （7.5 mm away from the lesion）. Results： The numbers of TUNEL-positive cells were significantly lower at the site of decompression on Day 1, and also at the rostral and caudal sites between Day 3 and Week 4 post-decompression, compared with the persistently compressed group. The numbers of cells between Day 1 and Week 4 were immunoreactive to caspase-3 and B-cell lymphoma-2 （Bcl-2）-associated X-protein （Bax）, but not to Bcl-2, correlated with those of TUNEL-positive cells. Conclusion： Our results suggest that decompression reduces neural cell apoptosis following spinal cord injury.

关键词： Spinal cord inj ury Decompression Apoptosis Terminal deoxynucleotidyl transferase (TdT)-mediated deoxyuridinetriphosphate nick-end labelling (TUNEL) Caspase-3 B-cell lymphoma-2 (Bcl-2) Bcl-2-associated X-protein (Bax)

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Low-pressure-induced large barocaloric effect in MnAs_(0.94)Sb_(0.06) alloy around room temperature

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Rare Metals 2023年第12期42卷 3977-3984页

作者： Peng-Tao Cheng Zhao Zhang xu-Cai kan Cheng-Liang Zhang Zheng-Ming Zhang Bing Li Dun-Hui Wang Division of Microelectronic Materials and Devices Hangzhou Dianzi UniversityHangzhou 310018China National Laboratory of Solid State Microstructures and Department of Physics Nanjing UniversityNanjing 210093China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China School of Materials Science and Engineering Anhui UniversityHefei 230601China Engineering Technology Research Center of Magnetic Materials School of Physics and Materials ScienceAnhui UniversityHefei 230601China

The barocaloric effect(BCE)is a promising alternative to traditional vapor compressing refrigeration because of its environmentally friendly impact and high energy ***,the driving hydrostatic pressure for most BCE materials is relatively high,which is not conducive to practical *** this paper,we report that the large barocaloric entropy change of MnAs_(0.94)Sb_(0.06)alloy can be induced by low hydrostatic *** phase transition temperature is strongly sensitive to the applied pressure,resulting in a large barocaloric coefficient of 134 K·GPa^(-1)on cooling and 126 K·GPa^(-1)on *** maximum barocaloric entropy change and adiabatic temperaturechange resulted from hydrostatic pressure of 40 MPa reach up to 26.3 J·kg^(-1)·K^(-1)and 14.4 K,respectively,showing an excellent barocaloric *** results demonstrate that the MnAs_(0.94)Sb_(0.06)alloy is a promising alternative for BCE refrigeration.

关键词： alloy hydrostatic

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Necroptosis contributes to deoxynivalenolinduced liver injury and inflammation in weaned piglets

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Journal of Animal Science and Biotechnology 2025年第1期16卷 182-192页

作者： Qilong xu Hanqiu Gong Mohan Zhou Junjie Guo Shaokui Chen kan Xiao Yulan Liu Hubei Key Laboratory of Animal Nutrition and Feed Science Wuhan Polytechnic UniversityWuhan 430023China

Background The aim of this study was to investigate the role of necroptosis in deoxynivalenol(DON)-induced liver injury and inflammation in weaned *** In Exp.1,12 weaned piglets were divided into 2 groups including pigs fed basal diet and pigs fed diet contaminated with 4 mg/kg DON for 21 *** Exp.2,12 weaned piglets were divided into 2 groups including con-trol piglets and piglets given a gavage of 2 mg/kg body weight(BW)*** Exp.3,24 weaned piglets were used in a 2×2 factorial design and the main factors including necrostatin-1(Nec-1)(DMSO or 0.5 mg/kg BW Nec-1)and DON challenge(saline or 2 mg/kg BW DON gavage).On 21 d in Exp.1,or at 6 h post DON gavage in Exp.2 and 3,pigs were killed for blood samples and liver *** histology,blood biochemical indicators,and liver inflamma-tion and necroptosis signals were *** Dietary or oral gavage with DON caused liver morphological damage in *** DON led to hepato-cyte damage indicated by increased aspartate transaminase(AST)activity and AST/alanine aminotransferase(ALT)ratio,and DON gavage also caused hepatocyte damage and cholestasis indicated by increased AST and alkaline phosphatase(AKP)*** DON caused liver necroptosis indicated by increased protein abundance of total receptor interacting protein kinase 3(t-RIP3)and total mixed lineage kinase domain-like protein(t-MLKL).Moreover,DON gavage increased mRNA expression of interleukin(IL)-6 and IL-1βin *** gavage also induced liver necroptosis demonstrated by increased protein abundance of t-RIP3,phosphorylated-RIP3(p-RIP3),t-MLKL and ***,pretreatment with Nec-1,a specific inhibitor of necroptosis,inhibited liver necroptosis indi-cated by decreased protein expression of t-RIP3,p-RIP3,t-MLKL and ***-1 pretreatment reduced liver morphological damage after DON *** with Nec-1 also attenuated liver damage induced by DON indicated by decreased activities of AST and ***,Nec-

关键词： Deoxynivalenol Liver damage Necroptosis Necrostatin-1 Pigs

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Spinal Cord Mapping of Respiratory Intercostal Motoneurons in Adult Mice

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Neuroscience Bulletin 2022年第12期38卷 1588-1592页

作者： Junhong Zhang Fenlan Luo Shuancheng Ren Yaling Wang Wu Li kan xu Ziyi Zheng Chao He Jianxia Xia Wei Xiong Zhi-An Hu Department of Geriatrics First Affiliated HospitalArmy Medical UniversityChongqing 400038China Department of Physiology College of Basic Medical SciencesArmy Medical UniversityChongqing 400038China

Dear Editor,Respiration is a vital and continuous physiological process depending on the output from spinal respiratory motoneurons to excite the inspiratory pump muscles[1-3].In mammals,phrenic motoneurons and intercostal motoneurons are the main spinal respiratory motoneurons,which innervate the diaphragm and intercostal muscles(IMs),respectively[4].

关键词： pump Mapping vital

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无绝缘轨道电路补偿电容多故障的快速诊断方法

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铁道学报 2018年第2期40卷 67-72页

作者：徐侃赵林海北京交通大学电子信息工程学院北京100044 北京交通大学轨道交通控制与安全国家重点实验室北京100044

针对一段轨道电路中存在多个补偿电容故障的情况,基于机车信号感应电压幅值包络的数学模型,以TCR接收信号的幅值趋势为特征,提出轨道电路补偿电容多故障的快速诊断方法。按补偿电容位置对TCR感应电压幅值包络曲线进行分段处理并计算每... 详细信息

针对一段轨道电路中存在多个补偿电容故障的情况,基于机车信号感应电压幅值包络的数学模型,以TCR接收信号的幅值趋势为特征,提出轨道电路补偿电容多故障的快速诊断方法。按补偿电容位置对TCR感应电压幅值包络曲线进行分段处理并计算每一段的特征,将每一段特征排列形成的特征序列从发送端向接收端查找其中的特定值,以实现故障的初步诊断和检测。针对特定的故障模式,采用一阶导数为约束条件进行二次判别,以实现准确的故障识别。试验表明,本文算法可以快速识别多个电容故障的情况,具有准确率高、实时性强等特点。目前已集成到TCR远程监测平台,可以实现对补偿电容的实时监测。

关键词：无绝缘轨道电路补偿电容故障诊断

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不同电压等级部分耦合线路的单回线故障分析

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电力系统自动化 2015年第12期39卷 81-87页

作者：许侃范春菊上海交通大学电子信息与电气工程学院上海市200240 国网上海市电力公司电力科学研究院上海市200437

由于建设时间的不同,因此输电系统中会出现不同电压等级部分耦合的输电线路。这种线路故障时,由于存在零序互感,给故障分析带来了难度。针对这一问题,将耦合部分的线路,先分别进行传统的序分量分解,得到完全解耦的正序分量、负序分量和... 详细信息

由于建设时间的不同,因此输电系统中会出现不同电压等级部分耦合的输电线路。这种线路故障时,由于存在零序互感,给故障分析带来了难度。针对这一问题,将耦合部分的线路,先分别进行传统的序分量分解,得到完全解耦的正序分量、负序分量和存在耦合的零序分量;然后再借鉴六序分量法的思路,把零序分为同向量和反向量,对零序互感进一步解耦;最后,利用零序电流电压之间的关系,对非耦合部分进行阻抗修正。根据故障时的边界条件,研究了不同电压等级部分耦合线路的序分量特征,给出了发生单回线故障时的复合序网图,解决了不同电压等级部分耦合线路故障计算的复杂问题。PSCAD仿真结果表明,该方法非常适用于不同电压等级部分耦合线路的故障分析,且短路分析计算具有精确性、实用性和有效性。

关键词：输电线路部分耦合零序互感解耦复合序网图故障分析

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