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Nano Research 2023年第2期16卷 2611-2621页

作者： Yuhan Wu Guodong Wang xixi yuan Gang Fang Peng Li Guangbin Ji College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016China Aerospace Research Institute of Material&Processing Technology Beijing 100076China

Heterogeneous interface engineering strategy is an effective method to optimize electromagnetic functional materials.However,the mechanism of heterogeneous interfaces on microwave absorption is still unclear.In this study,abundant heterointerfaces were customized in hierarchical structures via a collaborative strategy of lyophilization and hard templates.The impressive electromagnetic heterostructures and strong interfacial polarization were realized on the zero-dimensional(0D)hexagonal close-packed(hcp)-face-centered cubic(fcc)Co/two-dimensional(2D)Co(OH)_(2)nanosheets@three-dimensional(3D)porous carbon nanosheets(Co/Co(OH)_(2)@PCN).By controlling the carbonization temperature,the electromagnetic parameters were further adjusted to broaden the effective absorption bandwidth(EAB).Accordingly,the EAB of these absorbers were almost greater than 6 GHz(covering the entire Ku-band)in the thickness range of 2.0–2.2 mm except the sample S-1.0-800.As far as to the S-0.8-700 achieved an EAB up to 7.1 GHz at 2.2 mm and the minimum reflection loss(RLmin)value was−25.8 dB.Moreover,in the far-field condition,the radar cross section(RCS)of S-0.8-700 can be reduced to 19.6 dB·m^(2).We believe that this work will stimulate interest in interface engineering and provide a direction for achieving efficient absorbing materials.

关键词： microwave absorption wide bandwidth interface engineering hierarchical porous structure absorption mechanism

Low-voltage and high-gain WSe_(2)avalanche phototransistor with an out-of-plane WSe_(2)/WS_(2)heterojunction

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Nano Research 2023年第2期16卷 3422-3428页

作者： Lingyao Meng Ningning Zhang Maolong Yang xixi yuan Maliang Liu Huiyong Hu Liming Wang Department of Microelectronics Xidian UniversityXi’an 710000China

The properties of photodetectors based on two-dimensional materials can be significantly enhanced by avalanche effect.However,a high avalanche breakdown voltage is needed to reach impact ionization,which leads to high power consumption.Here,we report the unique features of a low-voltage avalanche phototransistor formed by an in-plane WSe_(2)field effect transistor(FET)with an out-of-plane WSe_(2)/WS_(2)P–N heterojunction(HJ FET).The avalanche breakdown voltage in the device can be decreased from−31 to−8.5 V when compared with that in WSe_(2)FET.The inherent mechanism is mainly related to the redistributed electric field in the WSe_(2)channel after the formation of the out-of-plane P–N heterojunction.When the bias voltage is−16.5 V,the photoresponsivity in the HJ FET is enhanced from 1.5 to 135 A/W,which is significantly higher than that in the WSe_(2)FET because of the obvious reduction of the avalanche breakdown voltage.Moreover,HJ FET shows a higher responsivity than WSe_(2)FET in the range of 400–1,100 nm under low bias voltage.This phenomenon is caused by accelerating electron–hole spatial separation in the heterojunction.These results indicate that the use of an WSe_(2)FET with an out-of-plane WSe_(2)/WS_(2)heterojunction is ideal for high-performance photodetectors with low power consumption.

关键词： avalanche breakdown voltage WSe_(2) WS_(2) heterojunction photodetector

基于技术驱动与服务创新的虚拟现实产业发展研究

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中国工程科学 2024年第1期26卷 35-44页

作者：袁茜茜吕星月冯大权王振中深圳大学数字创意研究中心深圳518060 中央广播电视总台技术局北京100020

虚拟现实(VR)技术以高度沉浸感为用户带来全新的多感官交互体验,推动产生新兴服务业态并以新服务模式促进传统行业转型升级,推动高附加值、高层次和多元化服务产业体系建设。本文梳理了VR产业链结构和关键技术发展现状,剖析了VR与服务... 详细信息

虚拟现实(VR)技术以高度沉浸感为用户带来全新的多感官交互体验,推动产生新兴服务业态并以新服务模式促进传统行业转型升级,推动高附加值、高层次和多元化服务产业体系建设。本文梳理了VR产业链结构和关键技术发展现状,剖析了VR与服务业融合应用的前景、方法与场景分类,分析了VR产业的发展趋势以及我国VR产业在产业链供给、应用落地、行业规范和专业人才培育等方面面临的主要问题。研究建议:加强基础研发投入,突破核心技术难点;培育领头试点项目,打造示范应用平台;构建配套服务体系,营造良好的产业发展环境;健全高技能人才队伍建设,提升我国在全球VR产业布局中的竞争优势,加速服务业的智能化、交互性、定制化发展。

关键词：虚拟现实技术新兴服务业产业链技术驱动融合发展

十八世纪淮扬社会士商关系新变初探——以袁枚与程梦星、程晋芳交往为例

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三门峡职业技术学院学报 2024年第1期23卷 86-91,114页

作者：刘习习安徽大学文学院安徽合肥230039

明中后期随着商业发展,商人阶层壮大,士阶层“弃儒就贾”蔚成风气,士商互动蔚为大观,并一直持续到十八世纪的清中叶,这种现象呈现出新面貌:士阶层出于对商人阶层财富的钦慕而越来越浸润着商人的心理,甚至直接涉足商界,从而兼具士人和商... 详细信息

明中后期随着商业发展,商人阶层壮大,士阶层“弃儒就贾”蔚成风气,士商互动蔚为大观,并一直持续到十八世纪的清中叶,这种现象呈现出新面貌:士阶层出于对商人阶层财富的钦慕而越来越浸润着商人的心理,甚至直接涉足商界,从而兼具士人和商人的双重角色特征;而商人阶层基于家族重儒的传统而潜心仕途,并最终成为士阶层的一员,表面上完成了从商人到士人的角色转换,但又不可能完全从商人的身份中剥离。欲探究这一时期士商关系的新变,可以袁枚和与其交游的程氏徽商程梦星、程晋芳为个案,考论淮扬社会一段文化与商业交游的史实。

关键词：清代淮扬社会士商互动新变袁枚程梦星程晋芳

天香丹改善心肌缺血再灌注损伤作用机制的网络药理学和分子对接技术研究

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中国中医急症 2024年第5期33卷 757-762,774页

作者：郭闫闫赵明芬袁茜茜新疆医科大学新疆乌鲁木齐830000 新疆医科大学附属中医医院新疆乌鲁木齐830000

目的通过网络药理学和分子对接技术研究天香丹改善心肌缺血再灌注损伤的药效物质基础和分子作用机制。方法借助中药系统药理学数据库和分析平台(TCMSP)并查阅文献获得天香丹中4味中药的主要活性成分,并将与活性成分相联系的靶基因借助Un... 详细信息

目的通过网络药理学和分子对接技术研究天香丹改善心肌缺血再灌注损伤的药效物质基础和分子作用机制。方法借助中药系统药理学数据库和分析平台(TCMSP)并查阅文献获得天香丹中4味中药的主要活性成分,并将与活性成分相联系的靶基因借助UniProt数据库翻译成相应基因。于PubChem数据库得到红景天、新塔花活性成分的详细信息,可以在TCMSP平台上找到该活性物质的靶基因,就使用TCMSP的结果,否则使用SwissTargetPrediction平台得到预测靶基因;利用GeneCards、OMIM、DISGENET和TTD数据库得到疾病相关靶点,对活性成分靶点与疾病靶点取交集后采用DAVID数据库进行基因本体(GO)功能以及京都基因与基因组百科全书(KEGG)富集分析;选择与本课题相关的通路cAMP、mTOR、核转录因子-κB(NF-κB)使用mapper工具构建KEGG通路图。最后通过AutoDock Vina软件对关键靶点和化合物进行分子对接。结果筛选出新塔花、红景天、丹参、降香针对心肌缺血再灌注损伤的128个活性成分和386个潜在作用靶点。蛋白质-蛋白质相互作用(PPI)网络拓扑分析发现白细胞介素-6(IL-6)、蛋白激酶B1(Akt1)、肿瘤坏死因子(TNF)的含量、白细胞介素-1β(IL-1β)等是天香丹治疗心肌缺血再灌注损伤的关键靶点。GO功能分析发现天香丹生物过程主要集中在RNA聚合酶Ⅱ启动子的转录正调控、基因表达的正向调控、凋亡过程的负调控、对外源刺激的反应等多个方面;KEGG信号富集分析结果显示主要涉及血脂与动脉粥样硬化、糖尿病并发症中的AGERAGE信号通路、TNF信号通路、细胞凋亡、IL-17信号通路、前列腺癌、HIF-1信号通路、cAMP信号通路、NF-κB信号通路、mTOR信号通路等。分子对接结果显示活性物质与靶点蛋白之间存在较强的结合力,其中槲皮素与TNF的结合力最强。结论天香丹治疗心肌缺血再灌注损伤具有多成分、多靶点、多通路相互协同的特点,为今后天香丹的临床应用提供了理论基础和参考。

关键词：心肌缺血再灌注损伤天香丹网络药理学分子对接

New perspective of skeletal stem cells

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Biomaterials Translational 2022年第4期3卷 280-294页

作者： Guixin yuan Zan Li xixi Lin Na Li Ren Xu The First Affiliated Hospital of Xiamen University-ICMRS Collaborating Centre for Skeletal Stem Cell State Key Laboratory of Cellular Stress BiologyFaculty of Medicine and Life SciencesXiamen UniversityXiamenFujian ProvinceChina Xiamen Key Laboratory of Regeneration Medicine Fujian Provincial Key Laboratory of Organ and Tissue RegenerationSchool of MedicineSchool of MedicineXiamen UniversityXiamenFujian ProvinceChina Department of Human Anatomy School of MedicineXiamen UniversityXiamenFujian ProvinceChina Department of Sports Medicine&Research Centre of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Tissue-resident stem cells are a group of stem cells distinguished by their capacity for self-renewal and multilineage differentiation capability with tissue specificity.Among these tissue-resident stem cells,skeletal stem cells(SSCs)were discovered in the growth plate region through a combination of cell surface markers and lineage tracing series.With the process of unravelling the anatomical variation of SSCs,researchers were also keen to investigate the developmental diversity outside the long bones,including in the sutures,craniofacial sites,and spinal regions.Recently,fluorescence-activated cell sorting,lineage tracing,and single-cell sequencing have been used to map lineage trajectories by studying SSCs with different spatiotemporal distributions.The SSC niche also plays a pivotal role in regulating SSC fate,such as cell-cell interactions mediated by multiple signalling pathways.This review focuses on discussing the spatial and temporal distribution of SSCs,and broadening our understanding of the diversity and plasticity of SSCs by summarizing the progress of research into SSCs in recent years.

关键词： bone repair endochondral ossification growth plate lineage tracing skeletal stem cells

Liver abscess and tracheal fistula induced by transcatheter arterial chemoembolization for hepatocellular carcinoma:A case report

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World Journal of Clinical Cases 2024年第16期12卷 2911-2916页

作者： Fu-Long Zhang Jing Xu Yu-Hong Jiang yuan-Dong Zhu Qian-Neng Wu Yan Shi Fang-yuan Zhu Jing-Wen Chen Liang-Xiao Wu Department of Gastroenterology Hangzhou Xixi HospitalHangzhou 310023Zhejiang ProvinceChina Department of Hepatopathy Hangzhou Xixi HospitalHangzhou 310023Zhejiang ProvinceChina

BACKGROUND Transarterial chemoembolization(TACE)is a standard treatment for intermediate-stage hepatocellular carcinoma(HCC).The complications of TACE include biliary tract infection,liver dysfunction,tumor lysis syndrome,biloma,partial intestinal obstruction,cerebral lipiodol embolism,etc.There are few reports about tracheal fistula induced by TACE.CASE SUMMARY A 42-year-old man came to our hospital with cough and expectoration for 1 month after TACE for HCC.Laboratory test results showed abnormalities of albumin,hemoglobin,prothrombin time,C-reactive protein,D-dimer,and prothrombin.Culture of both phlegm and liver pus revealed growth of Citrobacter flavescens.Computed tomography showed infection in the inferior lobe of the right lung and a low-density lesion with gas in the right liver.Liver ultrasound showed that there was a big hypoechoic liquid lesion without blood flow signal.Drainage for liver abscess by needle puncture under ultrasonic guidance was performed.After 1 month of drainage and anti-infection therapy,the abscess in the liver and the infection in the lung were reduced obviously,and the symptom of expectoration was relieved.CONCLUSION Clinicians should be alert to the possibility of complications of liver abscess and tracheal fistula after TACE for HCC.Drainage for liver abscess by needle puncture under ultrasonic guidance could relieve the liver abscess and tracheal fistula.

关键词： Tracheal fistula Liver abscess Transcatheter arterial chemoembolization Hepatocellular carcinoma Drainage Case report

Transparent cap adjusted the stent placed for stenosis after endoscopic injection of esophageal varices:A case report

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World Journal of Clinical Cases 2024年第15期12卷 2614-2620页

作者： Fu-Long Zhang Jing Xu yuan-Dong Zhu Qian-Neng Wu Yan Shi Lei Fang Dan Zhou Hai Wang Chao-JunHuang Chun-Hua Zhou Qun Zhu Department of Gastroenterology Hangzhou Xixi hospitalHangzhou 310023Zhejiang ProvinceChina Department of Hepatopathy Hangzhou Xixi hospitalHangzhou 310023Zhejiang ProvinceChina

BACKGROUND The stent embedded in the esophageal mucosa is one of the complications after stenting for esophageal stricture.We present a case of stent adjustment with the aid of a transparent cap after endoscopic injection of an esophageal varices stent.CASE SUMMARY A 61-year-old male patient came to the hospital with discomfort of the chest after the stent implanted for the stenosis because of endoscopic injection of esophageal varices.The gastroscopy was performed,and the stent embedded into the esophageal mucosa.At first,we pulled the recycling line for shrinking the stent,however,the mucosa could not be removed from the stent.Then a forceps was performed to remove the mucosa in the stent,nevertheless,the bleeding form the mucosa was obvious.And then,we used a transparent cap to scrape the mucosa along the stent,and the mucosa were removed successfully without bleeding.CONCLUSION A transparent cap helps gastroscopy to remove the mucosa embedded in the stent after endoscopic injection of the esophageal varices stent.

关键词： Stent Transparent cap Stenosis Endoscopic injection Esophageal varices Case report

Quantitative analysis of the morphing wing mechanism of raptors: Analysis methods, folding motions, and bionic design of Falco Peregrinus

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Fundamental Research 2024年第2期4卷 344-352页

作者： Di Tang Xipeng Huang Jinqi Che Weijie Jin Yahui Cui Yangjun Chen Yuxiao yuan Zhongyong Fan Weiwei Lu Siyu Wang Yin Yang Dawei Liu College of Mechanical Engineering Zhejiang University of TechnologyHangzhou 310014China Affiliated HangZhou xixi hospital Zhejiang University School of MedicineHangzhou 310023China Zhejiang Museum of Natural History Hangzhou 310014China High Speed Aerodynamic Institute China Aerodynamics Research and Development CenterMianyang 621000China

Raptors can change the shape and area of their wings to an exceptional degree in a fast and efficient manner,surpassing other birds,insects,or bats.Some researchers have focused on the functional properties of muscle skeletons,mechanics,and flapping robot design.However,the wing motion of the birds of prey has not been measured quantitatively,and synthetic bionic wings with morphing abilities similar to raptors are far from reality.Therefore,in the current study,a 3D suspension system for holding bird carcasses was designed and fabricated to fasten the wings of Falco Peregrinus with a series of morphing postures.Subsequently,the wing skeleton of the falcon was scanned during extending motions using the computed tomography(CT)approach to obtain three consecutive poses.Subsequently,the skeleton was reconstructed to identify the contribution of the forelimb bones to the extending/folding motions.Inspired by these findings,we propose a simple mechanical model with four bones to form a wing-morphing mechanism using the proposed pose optimisation method.Finally,a bionic wing mechanism was implemented to imitate the motion of the falcon wing—divided into inner and outer wings with folding and twisting motions.The results show that the proposed four-bar mechanism can track bone motion paths with high fidelity.

关键词： Falco Peregrinus Raptor Suspension system CT scan Bionic wings Four-bar mechanism

轻度认知障碍电子化认知评估工具的研究现状及展望

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护理管理杂志 2024年第4期24卷 299-303页

作者：张艾琳肖溪溪周纯祎张诗博袁越王思雪王云翠湖北中医药大学护理学院武汉市430065

轻度认知障碍是老年痴呆的前期阶段,对轻度认知障碍早期筛查评估可有效预防其向痴呆转变。电子化筛查评估工具快捷高效,是现阶段认知筛查的主流趋势。文章对国内外轻度认知障碍患者的电子化认知功能评估工具的内容、特点及应用情况进行... 详细信息

轻度认知障碍是老年痴呆的前期阶段,对轻度认知障碍早期筛查评估可有效预防其向痴呆转变。电子化筛查评估工具快捷高效,是现阶段认知筛查的主流趋势。文章对国内外轻度认知障碍患者的电子化认知功能评估工具的内容、特点及应用情况进行综述,指出目前电子化认知评估工具的优点及不足,并提出未来展望,旨在为今后引进和开发更适合我国轻度认知障碍患者特点的本土化认知评估工具提供参考。

关键词：认知障碍电子化评估工具研究进展