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The role of periodontal disease in atherosclerotic cardiovascular disease

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BIOCELL 2023年第7期47卷 1431-1438页

作者： xiwei zhao JINSONG WANG YIFAN XU JIAN ZHOU LEI HU Beijing Laboratory of Oral Health School of Basic MedicineSchool of StomatologyCapital Medical UniversityBeijing100069China Department of Biochemistry and Molecular Biology School of Basic MedicineCapital Medical UniversityBeijing100069China Immunology Research Center for Oral and Systemic Health Beijing Friendship HospitalCapital Medical UniversityBeijing100050China Research Unit of Tooth Development and Regeneration Chinese Academy of Medical SciencesBeijing100700China Department of VIP Dental Service School of StomatologyCapital Medical UniversityBeijing100050China

Atherosclerotic cardiovascular disease(ASCVD)includes a group of disorders of the heart and blood vessels and accounts for major morbidity and premature death *** is a chronic inflammatory disease with the gradual destruction of supporting tissues around the teeth,including gingiva,periodontal ligament,alveolar bone,and *** has been found to potentially increase the risk of ***,oral microorganisms and inflammation are the major factors for periodontitis to the incidence of ***,evidence has shown that the loss of masticatory function is another important factor of periodontitis to the incidence of *** this review,we illustrate the recent finding of the relationship between periodontitis and ASCVD,from a microscale perspective-oral microorganisms,inflammation,and tooth *** the high prevalence of periodontitis,it is important to add oral therapy as a regular ASCVD prevention *** dental visits could be a helpful strategy for ASCVD patients or general medical practitioners.

关键词： Oral microorganisms Chronic infection Tooth loss Periodontitis Atherosclerotic cardiovascular disease

基于区块链和聚合签名的可穿戴设备数据共享方案

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北京信息科技大学学报（自然科学版） 2024年第3期39卷 91-98页

作者：赵禧玮蔡英范艳芳李汶锦于晨北京信息科技大学计算机学院北京100192

可穿戴设备可以收集并共享数据来为健康监测、医学研究等提供帮助。区块链具有去中心化和不可篡改性,保证了共享数据在存储中的安全性,然而,在数据传输过程中仍面临潜在攻击者篡改伪造数据的问题。针对上述问题,提出了一种星际文件系统(... 详细信息

可穿戴设备可以收集并共享数据来为健康监测、医学研究等提供帮助。区块链具有去中心化和不可篡改性,保证了共享数据在存储中的安全性,然而,在数据传输过程中仍面临潜在攻击者篡改伪造数据的问题。针对上述问题,提出了一种星际文件系统(interplanetary file system, IPFS)结合区块链的架构以提升区块链效率,解决存储空间不足问题;设计了一种基于椭圆曲线的无证书无配对聚合签名方案,在数据上链前对其进行签名,实现了高效安全的数据传输。安全性分析证明所提签名方案可以防范大部分攻击;性能分析表明该方案相较于现有方案具有更低的计算开销和通信开销。

关键词：可穿戴设备数据共享区块链无证书无配对聚合签名

抗旱剂处理下泡椒生长生理指标的动态变化及生长模型

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南方农业 2024年第11期18卷 9-14页

作者：陈博庞发虎杜瑞卿赵玺炜陆孝楠南阳师范学院生命科学学院河南南阳473061

为提高泡椒的抗旱能力,观察并建立生长生理指标变化曲线模型,找到适合泡椒的抗旱剂及其最佳施用浓度,采用氯化钙和水杨酸2种抗旱剂的不同浓度浸泡泡椒种子,设置了土壤含水量正常组、干旱组及抗旱剂处理组(共8组),检测了泡椒5项生理生长... 详细信息

为提高泡椒的抗旱能力,观察并建立生长生理指标变化曲线模型,找到适合泡椒的抗旱剂及其最佳施用浓度,采用氯化钙和水杨酸2种抗旱剂的不同浓度浸泡泡椒种子,设置了土壤含水量正常组、干旱组及抗旱剂处理组(共8组),检测了泡椒5项生理生长指标,进行时间序列配对t检验和Logistic生长曲线函数模型分析。结果表明:与正常组相比,2种抗旱剂处理均提高了泡椒的抗旱能力,显著优于干旱组;测定的各项指标呈现出显著或极显著(p<0.05或p<0.01)的Logistic生长曲线特征;氯化钙抗旱剂浓度为600 mg·L^(-1)、水杨酸抗旱剂浓度为60 mg·L^(-1)时,抗旱效果较好,与正常组无显著差异,适宜选用。

关键词：泡椒抗旱剂 Logistic生长曲线函数时间序列配对t检验

Optimization of Crystal Structure Based on Experimentally Obtained XRD Patterns for Fluorescence of Sm³⁺-Doped TiO₂ Thin Films by Machine Learning

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Optics and Photonics Journal 2022年第6期12卷 147-155页

作者： Yuri Tamamoto Mariko Murayama xiwei zhao Department of Physics Tokyo University of Science Tokyo Japan Research Institute of Industrial Technology Toyo University Saitama Japan Department of Materials Science and Engineering Xihua University Chengdu China

The luminescence intensity of rare-earth ion-doped luminescent materials is closely related to the configuration of the anions around the rare-earth ions added to the host material and the lattice defects. And it is expected that this information will be reflected in the XRD pattern. In this study, the lumines-cence data and XRD patterns of Sm-doped TiO2 accumulated by our group are used to construct a model to predict the integrated luminescence intensity. The model was confirmed to be able to predict the integrated luminescence in-tensity with high accuracy. Furthermore, we found that the integrated lumi-nescence intensity of this system is closely related to the change in the position of the peak on the (200) plane of TiO2.

关键词： Machine Learning Phosphor TiO2

Construction of a Cu@hollow TS-1 nanoreactor based on a hierarchical full-spectrum solar light utilization strategy for photothermal synergistic artificial photosynthesis

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Carbon Energy 2024年第2期6卷 25-36页

作者： Sixian Zhu Qiao zhao Hongxia Guo Li Liu Xiao Wang xiwei Qi Xianguang Meng Wenquan Cui Hebei Key Laboratory for Environment Photocatalytic and Electrocatalytic Materials College of Chemical EngineeringNorth China University of Science and TechnologyTangshanChina School of Materials Science and Engineering National Institute for Advanced MaterialsTKL of Metal and Molecule-Based Material ChemistryNankai UniversityTianjinChina Hebei Iron and Steel Laboratory TangshanChina

The artificial photosynthesis technology has been recognized as a promising solution for CO_(2) *** catalysis has been proposed as a novel strategy to promote the efficiency of artificial photosynthesis by coupling both photochemistry and ***,strategies for maximizing the use of solar spectra with different frequencies in photothermal catalysis are urgently ***,a hierarchical full-spectrum solar light utilization strategy is *** on this strategy,a Cu@hollow titanium silicalite-1 zeolite(TS-1)nanoreactor with spatially separated photo/thermal catalytic sites is designed to realize high-efficiency photothermal catalytic artificial *** space-time yield of alcohol products over the optimal catalyst reached 64.4μmol g−1 h−1,with the selectivity of CH3CH2OH of 69.5%.This rationally designed hierarchical utilization strategy for solar light can be summarized as follows:(1)high-energy ultraviolet light is utilized to drive the initial and difficult CO_(2) activation step on the TS-1 shell;(2)visible light can induce the localized surface plasmon resonance effect on plasmonic Cu to generate hot electrons for H2O dissociation and subsequent reaction steps;and(3)low-energy near-infrared light is converted into heat by the simulated greenhouse effect by cavities to accelerate the carrier *** work provides some scientific and experimental bases for research on novel,highly efficient photothermal catalysts for artificial photosynthesis.

关键词： artificial photosynthesis full spectrum nanoreactors photothermal catalysis

Research on information technology of state monitoring and fault prediction for mechatronics system

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仪器仪表学报 2016年第S1期37卷 139-145页

作者： Xu Xiaoli Zuo Yunbo Meng Lingxia zhao xiwei Liu Xiuli Beijing Information Science & Technology University Beijing Institute of Technology

The safety and reliability of mechatronics systems,particularly the high-end,large and key mechatronics equipment in service,can strongly influence on production efficiency,personnel safety,resources and *** on the demands of development of modern industries and technologies such as international industry 4.0,Made-in-China 2025 and Internet + and so on,this paper started from revealing the regularity of evolution of running state of equipment and the methods of signal processing of low signal noise ratio,proposed the key information technology of state monitoring and earlyfault-warning for equipment,put forward the typical technical line and major technical content,introduced the application of the technology to realize modern predictive maintenance of equipment and introduced the development of relevant safety monitoring *** technology will play an important role in ensuring the safety of equipment in service,preventing accidents and realizing scientific maintenance.

关键词： mechatronics system information technology state monitoring fault prediction

“一带一路”倡议下国际投资仲裁机制的改革——边际裁量原则的引入

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福州大学学报（哲学社会科学版） 2023年第2期37卷 122-132页

作者：赵希伟中国人民大学法学院北京100872

以国际投资争端解决中心为代表的国际投资仲裁机制的“正当性危机”由来已久。由于国际投资争端解决中心的投资仲裁机制在构建过程中,对传统商事仲裁机制的借鉴、仲裁员制度的缺陷,以及案件受理数量短缺无法形成稳定的先例体系,使其在... 详细信息

以国际投资争端解决中心为代表的国际投资仲裁机制的“正当性危机”由来已久。由于国际投资争端解决中心的投资仲裁机制在构建过程中,对传统商事仲裁机制的借鉴、仲裁员制度的缺陷,以及案件受理数量短缺无法形成稳定的先例体系,使其在实践中造成投资者-东道国权益保护的失衡、裁决之间缺乏必要的一致性,从而诱发“正当性危机”。应对“正当性危机”,可以引入边际裁量原则,在充分承认东道国自由裁量权的基础上,通过比例原则予以限制,以克服国际投资争端解决中心投资仲裁机制固有偏重投资者保护的倾向,缓解仲裁裁决不一致的问题。中国在“一带一路”倡议下兼具投资者母国和东道国双重身份,应合理适用国际投资争端解决中心的投资仲裁机制,以推动国际投资仲裁机制改革,有效平衡并保护投资者与东道国权益,促进国际投资合作。

关键词： ICSID 投资仲裁正当性危机边际裁量原则

风力发电机高速齿轮磨损故障趋势预测方法研究

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太阳能学报 2023年第7期44卷 463-468页

作者：赵西伟张煜吴国新蒋章雷北京信息科技大学机电系统测控北京市重点实验室北京100192

以风力发电机高速齿轮磨损故障为研究对象,提出基于独立成分分析的高速齿轮磨损故障趋势预测方法。构建混合信息模型,应用独立成分分析方法将各独立成分信息的近似成分信息从混合信号中分离出来,并以纯净的近似故障源信号特征为依据找... 详细信息

以风力发电机高速齿轮磨损故障为研究对象,提出基于独立成分分析的高速齿轮磨损故障趋势预测方法。构建混合信息模型,应用独立成分分析方法将各独立成分信息的近似成分信息从混合信号中分离出来,并以纯净的近似故障源信号特征为依据找到有用成分;根据近似故障源信号与故障源信号互为相似形,利用正态总体均值区间估计方法估计相似形放大倍数值域;确定连续且单向变化的放大倍数值域与旋转部件故障程度的对应关系,建立故障程度判别标准,结合高速齿轮全生命周期故障源信号能量变化趋势图,对故障程度及趋势做出判断及预测。应用以上方法对工业现场采集到的高速齿轮磨损故障数据进行处理,结果表明,该方法对于处理以周期性突变为特征的磨损故障信号具有较理想的趋势预测效果。

关键词：风力发电机独立成分分析旋转机械信号处理特征提取

连接蛋白43磷酸化及其信号通路在脓毒症发生机制中的作用研究进展

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中华危重病急救医学 2022年第6期34卷 655-660页

作者：赵希伟刘凯侯林义张文凯山西医科大学第二附属医院心胸外科太原030001 山西医科大学第二附属医院重症医学科三病区太原030001

重症监护病房(ICU)患者死亡的主要原因是脓毒症,脓毒症及脓毒性休克严重影响患者的预后,增加了患者的病死率和再次发病率,早期、及时的干预可以降低脓毒症患者的病死率及复发率。脓毒症的发生可能与连接蛋白43(Cx43)的磷酸化有关,而Cx4... 详细信息

重症监护病房(ICU)患者死亡的主要原因是脓毒症,脓毒症及脓毒性休克严重影响患者的预后,增加了患者的病死率和再次发病率,早期、及时的干预可以降低脓毒症患者的病死率及复发率。脓毒症的发生可能与连接蛋白43(Cx43)的磷酸化有关,而Cx43的磷酸化需要通过各种信号通路实现。Cx43的相关位点通过不同信号通路发生磷酸化,实现了对脓毒症的精准调节,这些位点可能成为治疗脓毒症的相关靶点,为精准化治疗脓毒症提供方向。本文主要分析蛋白激酶A(PKA)、蛋白激酶C(PKC)、丝裂素活化蛋白激酶(MAPK)及磷脂酰肌醇3-激酶/蛋白激酶B(PI3K/Akt)等与Cx43相关的信号通路在脓毒症发生机制中的作用。

关键词：脓毒症连接蛋白43 信号通路发生机制