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MXene:An efficient hemoperfusion sorbent for the removal of uremic toxins

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Journal of Materiomics 2023年第6期9卷 1129-1140页

作者： Tianyi Wang Wei Gu Lu Yu Xin guo Jian Yang Xiaoyu Sun Jun Guan Lin Zhou Chengyin Wang Hang Yao xiuyun Zhang guoxiu Wang College of Chemistry and Chemical Engineering Yangzhou UniversityYangzhou225000Jiangsu ProvinceChina Centre for Clean Energy Technology School of Mathematics and PhysicsFaculty of ScienceUniversity of Technology SydneyBroadwaySydneyNSW2007Australia Clinical Medical College Su Bei People's HospitalYangzhou UniversityYangzhou225000Jiangsu ProvinceChina College of Physical Science and Technology Yangzhou UniversityYangzhou225000Jiangsu ProvinceChina

MXene,a family of two-dimensional(2D)transition metal carbides and nitrides have attracted extensive interests for many biochemical applications,including tumour elimination,biosensors,and magnetic resonance imaging(MRI).In this article,we firstly discovered that Ti3C2Tx MXene exhibited a highly efficient adsorption capability as hemoperfusion absorbent towards middle-molecular mass and protein bound uremic toxins in the end stage of renal disease(ESRD)*** scale investigations reveal that the high efficiency of MXene for the removal of uremic toxins could be attributed to synergistic effects of physical/chemical adsorption,electrostatic interaction surface of 2D MXene,and transformation of protein secondary structure.2D MXene materials could be used as a new hemoperfusion sorbent with ultrahigh efficiency for removing uremic toxins during the treatment of kidney disease.

关键词： 2D materials MXene Hemoperfusion Middle molecular weight toxin Protein bound toxin Adsorption

卧位康复操联合震荡呼气正压训练在中重度吸入性损伤患者肺康复中的应用研究

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中国呼吸与危重监护杂志 2024年第6期23卷 400-405页

作者：王蓉练慧斌陈虹孙四平孙秀云郭晓娟陆文婷曹柳兆杨爱春王庆苏北人民医院烧伤整形外科苏北人民医院护理部苏北人民医院重症医学科苏北人民医院呼吸与危重症医学科

目的探讨卧位康复操联合震荡呼气正压训练在中重度吸入性损伤患者肺康复中的应用效果。方法采用便利抽样法选取2021年1月—2023年3月苏北人民医院烧伤整形外科收治的57名中重度吸入性损伤患者为研究对象，随机分为A组、B组及C组。A... 详细信息

目的探讨卧位康复操联合震荡呼气正压训练在中重度吸入性损伤患者肺康复中的应用效果。方法采用便利抽样法选取2021年1月—2023年3月苏北人民医院烧伤整形外科收治的57名中重度吸入性损伤患者为研究对象，随机分为A组、B组及C组。A组予以常规治疗，B组在A组基础上实施卧位康复操，C组在B组基础上联合应用震荡呼气正压训练。比较三组干预前、干预后第1秒用力呼气容积（forced expiratory volume in the first second,FEV1）、用力肺活量（forced vital capacity,FVC）、痰液性状、咳痰难度、痰液黏稠度、日均排痰量、Borg气促评分、1分钟坐立试验情况。结果干预后三组FEV1、FVC、痰液黏稠度、日均排痰量、Borg气促评分、1分钟坐立试验改善值比较，差异有统计学意义（均P<0.05）。B组Borg气促评分、1分钟坐立试验改善值显著优于A组，差异有统计学意义（均P<0.05）。C组FEV1、FVC、痰液性状、咳痰难度、痰液黏稠度、日均排痰总量、Borg气促评分、1分钟坐立试验改善值显著优于A组，差异有统计学意义（均P<0.05）。C组FEV1、日均排痰量、Borg气促评分的改善值显著优于B组，差异有统计学意义（均P<0.05）。结论卧位康复操联合震荡呼气正压训练为中重度吸入性损伤患者提供肺康复，能有效提高患者运动能力及呼吸功能，改善患者生活质量。

关键词：吸入性损伤卧位康复操震荡呼气正压训练肺功能

Genomic mosaicism due to homoeologous exchange generates extensive phenotypic diversity in nascent allopolyploids

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National Science Review 2021年第5期8卷 23-37页

作者： Ying Wu Fan Lin Yao Zhou Jie Wang Shuai Sun Bin Wang Zhibin Zhang guo Li xiuyun Lin Xutong Wang Yue Sun Qianli Dong Chunming Xu Lei Gong Jonathan F.Wendel Zhiwu Zhang Bao Liu Key Laboratory of Molecular Epigenetics of the Ministry of Education Northeast Normal University Department of Crop & Soil Sciences Washington State University Brightseed Inc. Department of Ecology Evolution& Organismal BiologyIowa State University

Allopolyploidy is an important process in plant speciation, yet newly formed allopolyploid species typically suffer from extreme genetic bottlenecks. One escape from this impasse might be homoeologous meiotic pairing, during which homoeologous exchanges(HEs) generate phenotypically variable progeny. However,the immediate genome-wide patterns and resulting phenotypic diversity generated by HEs remain largely unknown. Here, we analyzed the genome composition of 202 phenotyped euploid segmental allopolyploid individuals from the fourth selfed generation following chromosomal doubling of reciprocal F1 hybrids of crosses between rice subspecies, using whole-genome sequencing. We describe rampant occurrence of HEs that, by overcoming incompatibility or conferring superiority of hetero-cytonuclear interactions, generate extensive and individualized genomic mosaicism across the analyzed tetraploids. We show that the resulting homoeolog copy number alteration in tetraploids affects known-function genes and their complex genetic interactions, in the process creating extraordinary phenotypic diversity at the population level following a single initial hybridization. Our results illuminate the immediate genomic landscapes possible in a tetraploid genomic environment, and underscore HE as an important mechanism that fuels rapid phenotypic diversification accompanying the initial stages of allopolyploid evolution.

关键词： nascent allopolyploidy homoeologous recombination phenotypic diversity plant evolution GWAS dosage effects epistasis

学思践悟培育科学素养,知行合一发挥“慧眼”专长——分析化学实验课程思政建设

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大学化学 2024年第2期39卷 196-202页

作者：宿艳王秀云郭慧敏张艳娟张馨文尚芸廷姜文凤大连理工大学化学学院辽宁大连116024

针对化学实验教学过程中所存在的思政要素与专业知识融入不够而导致的学生职业使命感和价值观薄弱问题,分析化学实验课程将思政元素有机融入到实验内容中,制定了知识、能力、素质有机融合的“三位一体”育人目标,建设了“六聚焦”的思... 详细信息

针对化学实验教学过程中所存在的思政要素与专业知识融入不够而导致的学生职业使命感和价值观薄弱问题,分析化学实验课程将思政元素有机融入到实验内容中,制定了知识、能力、素质有机融合的“三位一体”育人目标,建设了“六聚焦”的思政案例库,实施了“七融进”的课程思政教学举措,创新了“五联动”的思政育人设计,打造了有深度、有温度的挑战性课堂,与学生进行知识的对话、思维的对话和心灵的对话。

关键词：分析化学实验课程思政创新实践

THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN

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Chinese Journal of Reactive Polymers 2002年第1期11卷 85-90页

作者： ZHANG Yifeng guo Hong ZHANG Guangming YAN xiuyun YINShougen ZHANG Zhengpu Institute of Taitai Pharmaceutical Co.Ltd Shengzhen 518057China State Key Lab.of Functional Polymeric Materials for Adsorption and Separation Institute of Polymer Chemistry Nankai UniversityTianjin 300071China

Adsorption resin AAS was used for the separation and purification of milupeinan (M-13) from its mother liquor. The good adsorption property of AAS adsorption resin was found for milupeinan (M-13) compared with the Diaion CHP 20p. When acetone and water (2:1 in volume) were used as desorption reagents, it was found that 3 times of bed volume of the desorption reagents would make the AAS resin which was saturately adsorpted M-13 desorption completely. Also a macroporous anion exchange resin (Poly-4-vinylpyridine type) D-280 was used for the decolourization from M-13 solution. Good results was given when the sv=1~2.

关键词： AAS adsorption resin D-280 decoloulization resin Milupeinan (M-13)

On SS-quasinormal subgroups and the structure of finite groups

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Science China Mathematics 2011年第3期54卷 449-456页

作者： WEI XianBiao1,2 & guo xiuyun2, 1Department of Mathematics and Physics, Anhui Institute of Architecture and Industry, Hefei 230022, China 2Department of Mathematics, Shanghai University, Shanghai 200444, China Department of Mathematics and Physics Anhui Institute of Architecture and Industry Hefei China Department of Mathematics Shanghai University Shanghai China

A subgroup H of a finite group G is said to be an SS-quasinormal subgroup of G if there is a subgroup B of G such that G = HB and H permutes with every Sylow subgroup of B. In this paper, we investigate the structure of a group under the assumption that every subgroup with order pm of a Sylow p-subgroup P of G is SS-quasinormal in G for a fixed positive integer m. Some interesting results related to the p-nilpotency and supersolvability of a finite group are obtained. For example, we prove that G is p-nilpotent if there is a subgroup D of P with 1 < |D| < |P| such that every subgroup of P with order |D| or 2|D| whenever p = 2 and |D| = 2 is SS-quasinormal in G, where p is the smallest prime dividing the order of G and P is a Sylow p-subgroup of G.

关键词： S-quasinormal subgroups SS-quasinormal subgroups p-nilpotent groups supersolvable groups

Effects of the Chinese Herbal Medicine Based on Hachimi-jio-gan in Male Rats with the Adenine-Induced Osteopenia

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Journal of Traditional Chinese Medicine 2005年第3期25卷 226-232页

作者： Takeshi Ogirima Kaori Tano Masayuki Kanehara Ming Gao xiuyun Wang Yi guo Yanjun Zhang Liping guo Torao Ishida Graduate School of Health Science suzuka University of Medical Science 1001-1 Kishioka Suzuka Mie Pref. 510-0293 Japan Graduate School of Health Science Institute of Traditional Chinese Medicine Suzuka University ofMedical Science 1001-1 Kishioka Suzuka Mie Pref. 510-0293 Japan Graduate School of Health Science Suzuka University of Medical Science 1001-1 Kishioka Suzuka Mie Pref. 510-0293 Japan

In the adenine-induced renal failure rats, reversibility of renal failure and recovery of bone mineral density (BMD) by discontinuation of adenine-rich diet were reported: We think that the effect to bone metabolism with medication may be able to be evaluated as reinforcement of the BMD recovery. We have so far investigated the Chinese herbal medicine based on Hachimi-jio-gan (HJG) which are more effective than HJG alone. In this study, we investigated the effects of our Chinese herbal prescription on BMD in the adenine-treated rats compared to that of vitamin D3treatment. Young male rats were administrated 100 mg/ml adenine for 8 weeks, and they showed renal failure and bone loss. The adenine-treated rats were divided into the following 3 groups, that is, the group experienced no treatment (control), the group givenour Chinese herbal medicine (HAO), and the group given vitamin D3 (VD3) medication. It is likely that VD3 medication was less effective for increase of the femoral BMD than increase of the spinal BMD. In contrast, HAO was effective for increase of the femoral BMD. The VD3 group showed low deoxypyridinoline (Dpd: bone resorption maker) as compared to the control ***, the HAO group showed same or slightly high Dpd. It is suggested that VD3 may increase BMD by reduction of bone resorption, while HAO may show effect on BMD by activating bone metabolism. It is indicated that HAO may become a curative medicine for bone loss because of the different target site from vitamin D3.

关键词：中医药疗法腺嘌呤肾疾病骨密度

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黄河冲积平原甜樱桃引种对比试验技术报告

落叶果树 2024年第4期56卷 71-74页

作者：周长国刘峰李福玲訾本军高秀云山东省菏泽市成武县自然资源和规划局山东成武274200 山东省菏泽市成武县白浮图镇农业农村服务中心山东成武274200 山东省菏泽市成武县文亭街道办事处社区服务中心山东成武274200 山东省菏泽市成武县伯乐集镇农业农村服务中心山东成武274200

在黄河冲积平原,2018年引种试栽了美早、早大果、友谊、红灯、红宝石5个甜樱桃品种,对其性状表现包括生长结果习性、果实经济性状、抗逆性、物候期等进行观测对比,综合评价认为,早大果、美早表现较好,树姿开张、长势中庸、早期丰产,果... 详细信息

在黄河冲积平原,2018年引种试栽了美早、早大果、友谊、红灯、红宝石5个甜樱桃品种,对其性状表现包括生长结果习性、果实经济性状、抗逆性、物候期等进行观测对比,综合评价认为,早大果、美早表现较好,树姿开张、长势中庸、早期丰产,果个大、可溶性固形物含量高、硬度大、可食率高,品质优,抗逆性强,适宜在成武县发展。简介了栽培技术要点。

关键词：甜樱桃栽培管理技术 5个樱桃品种

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Band-gap tunable(Ga_(x)In_(1−x))_(2)O_(3)layer grown by magnetron sputtering

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Frontiers of Information Technology & Electronic Engineering 2021年第10期22卷 1370-1378页

作者： Fabi ZHANG Jinyu SUN Haiou LI Juan ZHOU Rong WANG Tangyou SUN Tao FU Gongli XIAO Qi LI Xingpeng LIU xiuyun ZHANG Daoyou guo Xianghu WANG Zujun QIN Guangxi Key Laboratory of Precision Navigation Technology and Application Guilin University of Electronic TechnologyGuilin 541004China Center for Optoelectronics Materials and Devices&Key Laboratory of Optical Field Manipulation of Zhejiang Province Zhejiang Sci-Tech UniversityHangzhou 310018China School of Mechanical Engineering Shanghai Dianji UniversityShanghai 200245China

Multicomponent oxide(Ga_(x)In_(1−x))_(2)O_(3)films are prepared on(0001)sapphire substrates to realize a tunable band-gap by magnetron sputtering technology followed by thermal *** optical properties and band structure evolution over the whole range of compositions in ternary compounds(Ga_(x)In_(1−x))_(2)O_(3)are investigated in *** X-ray diffraction spectra clearly indicate that(Ga_(x)In_(1−x))_(2)O_(3)films with Ga content varying from 0.11 to 0.55 have both cubic and monoclinic structures,and that for films with Ga content higher than 0.74,only the monoclinic structure *** transmittance of all films is greater than 86%in the visible range with sharp absorption edges and clear *** addition,a blue shift of ultraviolet absorption edges from 380 to 250 nm is noted with increasing Ga content,indicating increasing band-gap energy from 3.61 to 4.64 *** experimental results lay a foundation for the application of transparent conductive compound(Ga_(x)In_(1−x))_(2)O_(3)thin films in photoelectric and photovoltaic industry,especially in display,light-emitting diode,and solar cell applications.

关键词： (Ga_(x)In_(1−x))_(2)O_(3)films Band-gap tunable Magnetron sputtering