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Condensation of STM is critical for shoot meristem maintenance and salt tolerance in Arabidopsis

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Molecular Plant 2023年第9期16卷 1445-1459页

作者： xiuwei cao Qingwei Du Yahe Guo Ying Wang Yuling Jiao State Key Laboratory of Plant Genomics and National Center for Plant Gene Research(Beijing) Institute of Genetics and Developmental BiologyThe Innovative Academy of Seed DesignChinese Academy of SciencesBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBeijing 100049China Beijing Agro-Biotechnology Research Center Beijing Academy of Agriculture and Forestry SciencesBeijing 100097China State Key Laboratory of Protein and Plant Gene Research School of Life SciencesPeking UniversityBeijing 100871China Peking-Tsinghua Center for Life Sciences Center for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Peking University Institute of Advanced Agricultural Sciences Shandong Laboratory of Advanced Agricultural Sciences in WeifangWeifangShandong 261325China College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China

The shoot meristem generates the entire shoot system and is precisely maintained throughout the life cycle under various environmental *** this study,we identified a prion-like domain(PrD)in the key shoot meristem regulator SHOOT MERISTEMLESS(STM),which distinguishes STM from other related KNOX1 *** demonstrated that PrD stimulates STM to form nuclear condensates,which are required for maintaining the shoot *** nuclear condensate formation is stabilized by selected PrD-containing STM-interacting BELL proteins in vitro and in ***,condensation of STM promotes its interaction with the Mediator complex subunit MED8 and thereby enhances its transcriptional ***,condensate formation emerges as a novel regulatory mechanism of shoot meristem ***,we found that the formation of STM condensates is enhanced upon salt stress,which allows enhanced salt tolerance and increased shoot *** findings highlight that the transcription factor partitioning plays an important role in cell fate determination and might also act as a tunable environmental acclimation mechanism.

关键词： intrinsically disordered proteins KNOX1 shoot apical meristem biomolecular condensate salt stress axillary meristem

A self-activation loop maintains stem cell fate for branching

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A self-activation loop maintains stem cell fate for branchin...

神经网络定位中多点多映射概率样本增强方法研究

2018全国植物生物学大会

作者： xiuwei cao Yuling Jiao State Key Laboratory of Plant Genomics Institute of Genetics and Developmental BiologyChinese Academy of Sciences

Plants differ from most animals in their retained ability to initiate new cycles of growth and development,which relies on the establishment and activity of branch *** seed plants,branching is achieved by axillary meristems,which are established in the axil of each leaf base and develop into lateral *** meristems are initiated from a meristematic cell population originally detached from the shoot apical *** remains unclear how the meristematic cell fate is *** we show that the meristem marker gene SHOOT MERISTEMLESS(STM) can activates its own expression to enable cell fate ***,the self-activation loop requires an STM-interacting protein FEWER AXILLARY BRANCHING(FAB),whose mutants display compromised axillary bud *** and biochemical data suggest that the STM-FAB heterodimer binds and activates STM as well as additional axillary meristem regulatory *** together,our finding provides a striking example in which a self-activation loop maintains the meristematic cell fate to enable branching.

关键词： meristem stem cell cell lineage cell fate branching

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西安理工大学学报 2021年第2期37卷 209-214页

作者：杨静曹秀伟西安理工大学机械与精密仪器工程学院陕西西安710048 中建科技集团有限公司深圳分公司广东深圳518000

神经网络室内定位算法的定位精度取决于训练样本的数量和样本对数据特征的表征性,针对样本采集工作量大的问题,本文提出了一种多点多映射概率样本的增强方法。该方法首先根据无线信号的传播特性以及空间相关性,利用少量实测点数据,快速... 详细信息

神经网络室内定位算法的定位精度取决于训练样本的数量和样本对数据特征的表征性,针对样本采集工作量大的问题,本文提出了一种多点多映射概率样本的增强方法。该方法首先根据无线信号的传播特性以及空间相关性,利用少量实测点数据,快速构建多点反应环境影响的特征,然后利用概率法生成表征无线信号波动的多映射正态分布样本数据。实验结果表明,利用多点多映射概率样本增强方法生成的训练样本集,有效数据量大,信号表征性好,且人工采集工作量低,由此训练的神经网络定位算法定位精度高。

关键词：神经网络空间相关环境修正数据特征多映射概率样本

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土壤污染防治及修复的有效策略思考

皮革制作与环保科技 2021年第11期2卷 122-123页

作者：曹秀伟石家庄市正定环保服务中心河北石家庄050800

近年来,在科学技术的不断推动下,土壤污染防治技术不断完善和优化。然而,由于土壤污染因素的复杂性,在土壤处理和恢复过程中仍存在许多问题有待解决。在此基础上,本文对存在的问题进行了分析,并提出了有针对性的解决方案,为促进土壤整... 详细信息

近年来,在科学技术的不断推动下,土壤污染防治技术不断完善和优化。然而,由于土壤污染因素的复杂性,在土壤处理和恢复过程中仍存在许多问题有待解决。在此基础上,本文对存在的问题进行了分析,并提出了有针对性的解决方案,为促进土壤整治工程的顺利进行奠定了良好的基础。

关键词：土壤污染治理修复对策

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佛教医学说略

河南中医学院学报 2006年第1期21卷 18-20页

作者：曹秀伟山东大学宗教科学与社会问题研究所山东济南250100

佛教源于古印度,在传入中国的过程中,佛教对医学给予了一定程度的重视,借医弘佛,形成了有其特色的佛教医学。目前学术界对佛教医学的研究主要集中于对佛教经典中的医学资料和医学思想的探析。从各研究者对佛教医学的定义、基础理论、临... 详细信息

佛教源于古印度,在传入中国的过程中,佛教对医学给予了一定程度的重视,借医弘佛,形成了有其特色的佛教医学。目前学术界对佛教医学的研究主要集中于对佛教经典中的医学资料和医学思想的探析。从各研究者对佛教医学的定义、基础理论、临床治疗、医用咒语、养生保健等方面研究现状作了归纳和分析,以期对佛教医学研究的进一步发展有所裨益。

关键词：佛教医学借医弘佛《中国佛教医学丛书》

Tomographic inversion of OBS converted shear waves:case study of profile EW6 in the Dongsha area

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Acta Oceanologica Sinica 2024年第8期43卷 13-25页

作者： Genggeng Wen Kuiyuan Wan Shaohong Xia xiuwei Ye Huilong Xu Chaoyan Fan Jinghe cao Shunshan Xu CEA Key Laboratory of Earthquake Monitoring and Disaster Mitigation Technology Guangdong Earthquake AgencyGuangzhou 510070China Guangdong Science and Technology Collaborative Innovation Center for Earthquake Prevention and Disaster Mitigation Guangzhou 510070China MOE Key Laboratory of Disaster Forecast and Control in Engineering-Urban Earthquake Safety Laboratory Guangzhou 510070China CAS Key Laboratory of Ocean and Marginal Sea Geology South China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China 6 Centro de Geociencias Universidad Nacional Autónoma de MéxicoQuerétaroC.P.76230Mexico

Studies of converted S-wave data recorded on the ocean bottom seismometer(OBS)allow for the estimation of crustal S-wave velocity,from which is further derived the Vp/Vs ratio to constrain the crustal lithology and geophysical *** a precise S-wave velocity model is important for deep structural research,and inversion of converted S-waves provides a potential ***,the inversion of the converted S-wave remains a weakness because of the complexity of the seismic ray path and the inconsistent conversion *** this study,we introduced two travel time correction methods for the S-wave velocity inversion and imaged different S-wave velocity structures in accordance with the corresponding corrected S-wave phases using seismic data of profile EW6 in the northeastern South China Sea(SCS).The two inversion models show a similar trend in velocities,and the velocity difference is<0.15 km/s(mostly in the range of 0–0.1 km/s),indicating the accuracy of the two travel time correction methods and the reliability of the inversion *** to simulations of seismic ray tracing based on different models,the velocity of sediments is the primary influencing factor in ray tracing for S-wave *** the sedimentary layer has high velocities,the near offset crustal S-wave refractions cannot be *** contrast,the ray tracing of Moho S-wave reflections was not significantly impacted by the velocity of the *** two travel time correction methods have their own advantages,and the application of different approaches is based on additional *** works provide an important reference for future improvements in converted S-wave research.

关键词： converted S-wave S-wave velocity structure inversion ocean bottom seismometer northeastern South China Sea

Quantitative analysis of irrigation water productivity in the middle reaches of Heihe River Basin, Northwest China

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International Journal of Agricultural and Biological Engineering 2019年第5期12卷 119-125页

作者： Donghao Li Taisheng Du Yue cao Manoj Kumar Shukla Di Wu xiuwei Guo Shichao Chen Center for Agricultural Water Research in China China Agricultural UniversityBeijing 100083China Department of Plant and Environmental Sciences New Mexico State UniversityNM 88003USA

With the growing shortage of surface water resources,it is of great significance for improving the irrigation water productivity(IWP)to ensure the water and food *** contribution of the driving factors of the IWP and the rational regulation of the input factors of agricultural production is *** this paper,118 and 80 sampling points were selected in Pingchuan and Liaoquan irrigation districts(PLID,the spacing of sampling point is approximately 1 km)and the middle reaches of the Heihe River basin(MHRB,the spacing of sampling point is approximately 10 km),*** characteristics and management measures near the sampling points were *** showed that the average value of the IWP in MHRB was 1.67 kg/m3,with a moderate heterogeneity in the *** main driving factors of IWP were irrigation,fertilization and planting *** the PLID,the contribution rates of soil factors and management measures to IWP were 20.6%and 35.2%,respectively,and the contribution of soil factors to IWP increased to 43.8%in the MHRB,while the contribution rate of management measures decreased to 24.8%.It shows that in a small irrigation districts,from the perspective of farmers,the improvement of IWP should be mainly controlled by management measures,while in the large area of watershed scale,the spatial differences in soil factors also need to be considered by the government management departments,when they want to increase IWP through regulating management measures.

关键词： irrigation water productivity driving factors quantitative analysis partial least squares maize

Absent in melanoma 2 attenuates proliferation and migration and promotes apoptosis of human colorectal cancer cells by activating P38MAPK signaling pathway

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Oncology Research 2024年第2期32卷 353-360页

作者： ZHI ZHANG XIAOSONG LI YING ZHANG HAO ZHU ZHENGUO QIAO YANG LU xiuwei MI HUIHUA cao GENHAI SHEN SONGBING HE Department of General Surgery Suzhou Ninth People’s HospitalSuzhou Ninth Hospital Affiliated to Soochow UniversitySuzhouChina Medical College of Nantong University NantongChina Department of Gastroenterology Suzhou Ninth People’s HospitalSuzhou Ninth Hospital Affiliated to Soochow UniversitySuzhouChina Department of General Surgery The First Affiliated Hospital of Soochow UniversitySuzhouChina Department of Oncological Surgery Kunshan Traditional Hospital Affiliated to Nanjing University of Chinese MedicineKunshanChina

Colorectal cancer(CRC)stands among the top prevalent cancers worldwide and holds a prominent position as a major contributor to cancer-related mortality *** in melanoma 2(AIM2),a constituent of the interferoninducible hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats protein family,contributes to both cancer progression and inflammasome *** this understanding,the precise biological functions and molecular mechanisms governed by AIM2 in CRC remain ***,this study endeavors to assess AIM2’s expression levels,explore its potential antitumor effects,elucidate associated cancer-related processes,and decipher the underlying signaling pathways in *** findings showed a reduced AIM2 expression in most CRC cell *** of AIM2 levels suppressed CRC cell proliferation and migration,altered cell cycle by inhibiting G1/S transition,and induced cell *** research uncovered the participation of P38 mitogen-activated protein kinase(P38MAPK)in AIM2-mediated modulation of CRC cell apoptosis and ***,our achievements distinctly underscored AIM2’s antitumor role in ***2 overexpression inhibited proliferation and migration and induced apoptosis of CRC cells via activating P38MAPK signaling pathway,indicating AIM2 as a prospective and novel therapeutic target for CRC.

关键词： Absent in melanoma 2 Proliferation Migration Apoptosis P38MAPK Colorectal cancer

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溶液除湿能力强化

化工学报 2008年第10期59卷 2442-2447页

作者：李秀伟张小松王庚曹熔泉东南大学能源与环境学院江苏南京210096

利用溶液除湿的制冷空调系统有着非常积极的节能意义,但与固体吸附除湿相比,溶液吸收除湿暴露了它除湿能力较差的缺点,这使它的应用普及受到了一定程度上的抑制。为了提高溶液除湿能力,本文介绍了从除湿器和除湿溶液两个方面进行改进的... 详细信息

利用溶液除湿的制冷空调系统有着非常积极的节能意义,但与固体吸附除湿相比,溶液吸收除湿暴露了它除湿能力较差的缺点,这使它的应用普及受到了一定程度上的抑制。为了提高溶液除湿能力,本文介绍了从除湿器和除湿溶液两个方面进行改进的研究结果:利用固体吸附剂对溶液除湿器表面进行了处理;利用混合溶液作为溶液除湿剂。本文利用电解质溶液理论对LiCl和CaCl2为代表的混合溶液进行了相关热物性的研究,并提出了选择理想溶液除湿剂及其合适配比的解决方案;进行了相应的除湿实验:实验结果揭示了改进的除湿器不仅从增大除湿面积方面对溶液除湿能力强化有所贡献,还可能存在着吸附势叠加的功效;混合溶液的使用使得溶液除湿能力相对于使用单种溶液大大提高。

关键词：溶液除湿除湿能力固体吸附剂活度系数