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Trends of alkaline phosphatase to prealbumin ratio in patients with hepatitis B linked to hepatocellular carcinoma development

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World Journal of Gastroenterology 2025年第2期31卷 42-51页

作者： Wen-Chong Zhen Jing sun Xue-Ting Bai Qian zhang Zi-Han li Yi-Xin zhang rong-Xuan Xu Wei Wu Zhi-Han Yao Chun-Wen Pu Xiao-Feng li School of Public Health Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Graduate School Dalian Medical UniversityDalian 116044Liaoning ProvinceChina Dalian Public Health Clinical Center Dalian Municipal Research Institute for Public HealthDalian 116001Liaoning ProvinceChina Department of Epidemiology and Health Statistics Dalian Medical UniversityDalian 116044Liaoning ProvinceChina

BACKGROUND Chronic hepatitis B often progresses silently toward hepatocellular carcinoma(HCC),a leading cause of mortality *** detection of HCC is crucial,yet *** To investigate the role of dynamic changes in alkaline phosphatase to prealbumin ratio(APR)in hepatitis B progression to *** Data from 4843 patients with hepatitis B(January 2015 to January 2024)were *** incidence rates in males and females were compared using the log-rank *** were evaluated using Kaplan–Meier *** linear Mixed-Effects Model was applied to track the fluctuation of APR levels over ***,Joint Modeling of Longitudinal and Survival data was employed to investigate the temporal relationship between APR and HCC *** The incidence of HCC was higher in *** ensure the model’s normality assumption,this study applied a logarithmic transformation to APR,yielding *** levels were higher in females(t=5.26,Pline APR link,rising APR indicates a higher HCC risk.

关键词： Alkaline phosphatase to prealbumin ratio Chronic hepatitis B patients Hepatocellular carcinoma Retrospective cohort study linear Mixed-Effect Mode Joint Modelling of Longitudinal and Survival data

Synthesis and Characterization of Monodisperse Emulsion Copolymer

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Chemical Research in Chinese Universities 2016年第1期32卷 134-139页

作者： JIANG Yan sun Xu li bin REN Xiaojun zhang Hongwen zhang rong School of Material Science and Engineering Changzhou University Changzhou 213164 P. R. China Department of Chemistry College of Liberal Arts and Sciences University of Colorado Denver 80217-3364 USA Jiangsu Chenguang Paint Co. Ltd. Changzhou 213154 P. R. China

Monodisperse emulsion copolymer was synthesized by semi-continuous core-shell emulsion polymerization of styrene, butyl acrylate and γ-methacryloxypropyl trimethoxy silane（KH570）. The emulsion particles size and its polydispersion were measured by dynamic light scattering（DLS）. The properties of emulsion copolymer were characterized by differential scanning calorimetry（DSC）, thermogravimetric analysis（TGA） and measurement of contact angle. The particle morphology was observed under a transmission electron microscope（TEM） and atomic force microscopy（AFM）. The results indicate that emulsion nanoparticles containing silicon possess core-shell structures and narrow polydispersity（PDI≤0.08）. The thermal stability and hydrophobicity of emulsion copolymer were improved with KH570 introduced into the system.

关键词： γ-Methacryloxypropyl trimethoxy silane(KH570) Emulsion polymerization Monodisperse nanoparticle

New quantification of symmetry energy from neutron skin thicknesses of^(48)Ca and^(208)Pb

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Nuclear Science and Techniques 2024年第10期35卷 188-196页

作者： rong An Shuai sun li-Gang Cao Feng-Shou zhang School of Physics Ningxia UniversityYinchuan 750021China Key Laboratory of Beam Technology of the Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Key Laboratory of Beam Technology of the Ministry of Education Institute of Radiation TechnologyBeijing Academy of Science and TechnologyBeijing 100875China Center of Theoretical Nuclear Physics National Laboratory of the Heavy Ion Accelerator of LanzhouLanzhou 730000China

Precise knowledge of the nuclear symmetry energy can be tentatively calibrated using multimessenger *** neutron skin thickness of a heavy nucleus is one of the most sensitive indicators for probing the isovector components of effective interactions in asymmetric nuclear *** studies have suggested that the experimental data from the CREX and PREX2 collaborations are not mutually compatible with existing nuclear *** this study,we review the quantification of the slope parameter of the symmetry energy L from the neutron skin thicknesses of^(48)Ca and^(208)*** energy density functionals classified by various isoscalar incompressibility coefficients K were employed to evaluate the bulk properties of finite *** calculated results suggest that the slope parameter L deduced from^(208)Pb is sensitive to the compression modulus of symmetric nuclear matter,but not that from^(48)*** effective parameter sets classified by K=220 MeV can provide an almost overlapping range of L from^(48)Ca and^(208)Pb.

关键词： Nuclear symmetry energy Neutron skin thickness Energy density functional

Constraining nuclear symmetry energy with the charge radii of mirror-pair nuclei

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Nuclear Science and Techniques 2023年第8期34卷 154-163页

作者： rong An Shuai sun li-Gang Cao Feng-Shou zhang Key Laboratory of Beam Technology of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Key Laboratory of Beam Technology of Ministry of Education Institute of Radiation TechnologyBeijing Academy of Science and TechnologyBeijing 100875China CAS Key Laboratory of High Precision Nuclear Spectroscopy Institute of Modern PhysicsChinese Academy of SciencesLanzhou 730000China Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator of LanzhouLanzhou 730000China

The nuclear charge radius plays a vital role in determining the equation of state of isospin asymmetric nuclear *** on the correlation between the differences in charge radii of mirror-partner nuclei and the slope parameter(L)of symmetry energy at the nuclear saturation density,an analysis of the calibrated slope parameter L was performed in finite *** this study,relativistic and nonrelativistic energy density functionals were employed to constrain the nuclear symmetry energy through the available databases of the mirror-pair nuclei^(36)Ca–^(36)S,^(38)Ca–^(38)Ar,and ^(54)Ni–^(54)*** deduced nuclear symmetry energy was located in the range 29.89–31.85 MeV,and L of the symmetry energy essentially covered the range 22.50–51.55 MeV at the saturation ***,the extracted L_(s) at the sensitivity density p_(s)=0.10 fm^(-3) was located in the interval range 30.52–39.76 MeV.

关键词： Symmetry energy Charge radii Mirror nuclei

Sttudy on intelligent spatial decision support system of agriculture

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哈尔滨工程大学学报 2006年第B07期27卷 607-611页

作者： zhang rong-mei sun Jie-li Information Technology College Hebei University of Economics And Trades Shijiazhuang 050061 China

This paper studies how to apply GIS, ES, and Data mining and WEB technologies in agriculture Decision Support System, with the researching background of Hebei expert system for farming soil variable rate fertilization. A model of agriculture intelligent spatial decision support system is built and the key technologies to implement this system are described in details.

关键词：农业地理信息系统专家系统智能决策支持系统

Synthesis and Structure of O-Ethyl S-Hydrogen Isoquinolin-1-ylcarbonothioimidate

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Chinese Journal of Structural Chemistry 2006年第5期25卷 604-608页

作者： YU Yun liN li-rong YOU Jun HUANG rong-bin ZHENG Lan-sun Department of Chemistry Longyan College Longyan Fujian 364000 China Department of Chemistry Xiamen University Xiamen 361005 China State Key Laboratory for Physical Chemistry of Solid Surfaces Xiamen University Xiamen 361005 China

O-Ethyl S-hydrogen isoquinolin-l-ylcarbonothioimidate was synthesized and its structure was characterized by IR, MS, ^1H NMR, elemental analysis and single-crystal X-ray diffraction. The crystal belongs to monoclinic, space group P21/c with a = 10.9471（19）, b = 9.3968（17）, c = 10.6125（19） A, β = 100.761 （3）°, V = 1072.5（3） A^3, Z = 4, Dc = 1.439 g/cm^3, F（000） = 488 and μ = 0.279 mm^-1. A total of 7763 reflections were collected, of which 2090 were unique. The structure was refined to the final R = 0.0322 and wR = 0.0882 for 2016 observed reflections with Ⅰ 〉 2σ（Ⅰ）. The crystal structure shows that there are intramolecular N-H…S hydrogen bonds and π-π stacking interactions between adjacent molecules.

关键词： O-ethyl S-hydrogen isoquinolin-1-ylcarbonothioimidate synthesis crystal structure

Gradually activated lithium uptake in sodium citrate toward high-capacity organic anode for lithium-ion batteries

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Rare Metals 2021年第6期40卷 1366-1372页

作者： rong Long Gu-lian Wang Zhong-li Hu Peng-Fei sun li zhang College of Chemistry Chongqing Normal UniversityChongqing 401331China College of Energy Soochow Institute for Energy and Materials Innovations and Key Laboratory of Advanced Carbon Materials and Wearable Energy Technologies of Jiangsu ProvinceSoochow UniversitySuzhou 215006China

lithium-ion batteries(liBs)have been used to power various electric devices and store energy,but their toxic components by using inorganic materials generally cause serious environmental issues when ***,environmentally friendly and naturally abundant organic compounds have been adopted as promising electrode materials for next-generation ***,a new organic anode electrode based on sodium citrate is proposed,which shows gradually activated electrochemical behavior and delivers a high reversible capacity of 776.8 mAh·g^(-1)after 1770 cycles at a current density of 2 A·g^(-1).With the aid of the electrochemical characterization,Fourier-transform infrared(FTIR)and X-ray photoelectron spectroscopy(XPS)analysis,the lithium uptake mechanism of sodium citrate-based anodes is identified to be a combination of three-electron lithiation/delithiation and fast li+intercalation/deintercalation processes,in which Faradaic reactions could offer a theoretical contribution of312 mAh·g^(-1)and intercalation pseudocapacitance would provide extra *** work demonstrates the great potential for developing high-capacity organic electrodes for liBs in future.

关键词： Faradaic lithiation lithium-ion battery li+intercalation pseudocapacitance Multiple lithium-ion storage mechanism Sodium citrate-based anode

Research trends of cancer metabolism:analysis from a Chinese perspective

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Cancer Communications 2022年第5期42卷 367-373页

作者： Yang li Jun liu lichao sun bin zhang rong Shi Department of Genetics School of Life ScienceAnhui Medical UniversityHefeiAnhui 230031P.R.China Department of Health Sciences National Natural Science Foundation of ChinaBeijing 100085P.R.China Department of Thoracic Surgery Zhongnan Hospital of Wuhan UniversityWuhanHubei 430000P.R.China State Key Laboratory of Molecular Oncology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021P.R.China Department of Lung Cancer Tianjin Medical University Cancer Institute and HospitalNational Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjin’s Clinical Research Center for CancerTianjin 300060P.R.China

1 INTRODUCTION Association between aberrant metabolism and tumor progression has been discovered and studied for a long period of time,and reprogramming of metabolism has become one of the key characteristics of cancer cells[1,2].Numerous studies showed that metabolic disorders are closely related to cancer risk and cancer-related deaths[3].According to the reports by the International Agency for Research on Cancer(IARC)and World Cancer Research Fund(WCRF),besides smoking,obesity and alcohol have become the most important risk factors of cancer worldwide[4].

关键词： metabolism cancer Cancer

Multi-sensor control for precise assembly of optical components

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Chinese Journal of Aeronautics 2014年第3期27卷 613-621页

作者： Ma li rong Weibin sun lining School of Mechatronic Engineering and Automation Shanghai University State Key Laboratory of Robotics and System Harbin Institute of Technology

In order to perform an optical assembly accurately, a multi-sensor control strategy is developed which includes an attitude measurement system, a vision system, a loss measurement system and a force sensor. A 3-DOF attitude measuring method using linear variable differential transformers （LVDT） is designed to adjust the relation of position and attitude between the spher- ical mirror and the resonator. A micro vision feedback system is set up to extract the light beam and the diaphragm, which can achieve the coarse positioning of the spherical mirror in the optical assembly process. A rapid self-correlation method is presented to analyze the spectrum signal for the fine positioning. In order to prevent the damage of the optical components and realize sealing of the resonator, a hybrid force-position control is constructed to control the contact force of the optical components. The experimental results show that the proposed multi-sensor control strategy succeeds in accomplishing the precise assembly of the optical components, which consists of parallel adjustment, macro coarse adjustment, macro approach, micro fine adjustment, micro approach and optical contact. Therefore, the results validate the multi-sensor control strategy.

关键词： Assembly Attitude measurement Force control Multi-sensor Vision