检索结果-南通市图书馆

基于近红外光谱技术结合ARO-LSSVR的天麻中有效成分含量快速检测

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

食品科学 2024年第4期45卷 207-213页

作者：李珊珊张付杰李丽霞张浩段星桅史磊崔秀明李小青昆明理工大学现代农业工程学院云南昆明650500 江苏大学电气信息工程学院江苏镇江212000 中国人民解放军69223部队新疆阿克苏842300

为实现对天麻中天麻素和对羟基苯甲醇含量的快速、无损检测,以云南昭通乌天麻为实验对象,采集900~1 700 nm波长范围内的光谱数据。首先,采用卷积平滑和标准正态变量变换进行光谱数据预处理,其次通过竞争性自适应重加权采样法(competitiv... 详细信息

为实现对天麻中天麻素和对羟基苯甲醇含量的快速、无损检测,以云南昭通乌天麻为实验对象,采集900~1 700 nm波长范围内的光谱数据。首先,采用卷积平滑和标准正态变量变换进行光谱数据预处理,其次通过竞争性自适应重加权采样法(competitive adapative reweighted sampling,CARS)与迭代保留信息变量算法进行特征波长的提取,根据基于特征波长建立最小二乘支持向量回归(least squares support vector machine,LSSVR)模型的结果,选择最佳特征波长提取方法。为了提高模型的准确率,本研究引入人工兔智能算法对LSSVR中的正则化参数γ和核函数密度σ2进行优化,并与粒子群优化算法(particle swarm optimization,PSO)、灰狼优化算法(grey wolf optimizer,GWO)进行对比,评估人工兔优化算法(artificial rabbits optimization,ARO)的优越性。结果表明,ARO算法在寻优速度、寻优能力上优于PSO、GWO;天麻素、对羟基苯甲醇的最佳预测模型均为CARS-AROLSSVR,其Rp2分别为0.969 6和0.957 7,预测均方根误差分别为0.014和0.020。综上,近红外光谱可用于天麻中有效成分的定量检测,本研究可为天麻快速检测装置的研发提供理论依据。

关键词：近红外光谱天麻最小二乘支持向量回归人工兔优化算法

在线全文

学校读者我要写书评

暂无评论

农业生物防治技术的现状及改进策略

生物技术进展 2024年第5期14卷 697-711页

作者：吴焕振杨野崔秀明刘源昆明理工大学生命科学与技术学院昆明650500 云南省三七重点实验室昆明650500 国家中医药管理局三七资源可持续开发利用重点实验室昆明650500 昆明市名药可持续开发利用重点实验室昆明650500

在全球人口增长和耕地减少的双重压力下,农业的可持续发展迫在眉睫。生物防治通过利用天敌、微生物等有益生物抑制害虫和病原体,展现出巨大的潜力,是现代农业病虫害防治的有效途径。概述了生物防治在农业可持续发展中的重要性及其在保... 详细信息

在全球人口增长和耕地减少的双重压力下,农业的可持续发展迫在眉睫。生物防治通过利用天敌、微生物等有益生物抑制害虫和病原体,展现出巨大的潜力,是现代农业病虫害防治的有效途径。概述了生物防治在农业可持续发展中的重要性及其在保护生物多样性和环境中的积极作用,详述了害虫天敌的应用、有益微生物防治植物病害、拮抗菌筛选技术的发展,以及组学技术和纳米技术的应用。最后,提出若干改进策略,旨在为生物防治相关研究和实际应用提供有价值的参考和指导,从而提高对生物防治技术的认识和应用,促进农业可持续发展。

关键词：生物防治农业可持续发展防治方法动物微生物

维普期刊数据库博看期刊

基于网络药理学探究三七叶对糖尿病大鼠的治疗机制

在线全文

学校读者我要写书评

暂无评论

实用中医内科杂志 2024年第6期38卷 21-24,I0008-I0011页

作者：于颖王承潇杨野崔秀明昆明理工大学生命科学与技术学院云南昆明650500 云南省三七资源可持续利用重点实验室云南昆明

目的利用网络药理学和动物实验,研究三七叶抗糖尿病的主要活性成分和潜在作用机制。方法基于Pubchem、PharmMapper、OMIM等数据库筛选三七叶与糖尿病共同的潜在靶点之后,再利用STRING数据库和Cytoscape软件构建蛋白相互作用网络图,对... 详细信息

目的利用网络药理学和动物实验,研究三七叶抗糖尿病的主要活性成分和潜在作用机制。方法基于Pubchem、PharmMapper、OMIM等数据库筛选三七叶与糖尿病共同的潜在靶点之后,再利用STRING数据库和Cytoscape软件构建蛋白相互作用网络图,对其进行拓扑学分析和聚类分析获得核心靶点,并进行GO和KEGG富集分析筛选药物作用于疾病的可能机制。随后进行动物实验验证三七叶的抗糖尿病作用。结果预测结果共获得三七叶与糖尿病的共同靶点50个,核心靶点有3个:ANXA5、CFB、GSTP1,共涉及生物过程986种,细胞组成15种,分子功能74种,信号通路101条。动物实验表明三七叶可降低糖尿病大鼠的血糖,减少与糖尿病肾病相关的p38 MAPK和TGF-β1 mRNA的表达,同时也可以调节氧化应激和血脂水平,减少动脉粥样硬化。结论三七叶是通过多途径多靶点共同发挥抗糖尿病的作用,其作用机制可能与减少氧化应激、调节细胞因子、减少动脉粥样硬化和抗糖尿病肾病肾纤维化等有关。

关键词：网络药理学三七叶糖尿病信号通路

不同产区晒烟致香成分分析及在电子烟中的应用

在线全文

学校读者我要写书评

暂无评论

香料香精化妆品 2024年第4期 179-186页

作者：杨君谢琦崔秀明郭亚勤徐晓炯华宝香精股份有限公司上海201821

为明确不同产区晒烟致香成分对电子烟加香的影响,对云南和东北2个产区的6个晒烟样品进行了精油提取,并利用气相色谱质谱联用仪对精油中的致香成分进行分析,同时进行电子烟加香试验和评吸。结果显示,不同产区晒烟的致香成分有较大差异。... 详细信息

为明确不同产区晒烟致香成分对电子烟加香的影响,对云南和东北2个产区的6个晒烟样品进行了精油提取,并利用气相色谱质谱联用仪对精油中的致香成分进行分析,同时进行电子烟加香试验和评吸。结果显示,不同产区晒烟的致香成分有较大差异。云南晒烟致香成分中醇类和酮类成分明显高于东北晒烟,醛类和酸类成分含量云南晒烟明显低于东北晒烟。电子烟加香感官评吸显示,云南晒烟整体香气细腻甜润,具有典型晾晒烟香气特征的同时,亦具有一定的烤烟香特征和清甜香香韵;东北晒烟整体香气强度较大,爆发力较强,具有显著的晾晒烟香与青香特征,其烟气细腻程度和丰富性程度略低于云南晒烟。致香成分分析与电子烟的感官评吸结果一致,可为深入研究不同产区晒烟风格特征及在电子烟烟油的调配提供理论依据。

关键词：晒烟不同产区致香成分电子烟加香感官评价

Cross-linkedα-amylase aggregates on Fe3O4 magnetic nanoparticles modified with polydopamine/polyethyleneimine for efficient hydrolysis of starch

在线全文

学校读者我要写书评

暂无评论

Particuology 2024年第7期90卷 98-105页

作者： Jiandong cui xiuming Tang Qingqing Ma Yuyan Chang Qunli Zhang Shiru Jia State Key Laboratory of Food Nutrition and Safety Laboratory of Industrial Fermentation MicrobiologyMinistry of EducationTianjin University of Science and TechnologyTianjin 300457China Key Laboratory of Biomass Chemical Engineering of Ministry of Education Zhejiang UniversityHangzhou 310027China

In this workα-amylase was immobilized on magnetic Fe3O4 nanoparticles with polyethylenimine(PEI)/polydopamine(PDA)coating or 3-aminopropyl triethoxysilane(APTES)for the first time via adsorption–precipitation–*** with the freeα-amylase,the resultant magnetic cross-linkedα-amylase aggregates(PEI/PDA-M-CLEAs and N-M-CLEAs)exhibited excellent thermal and storage stability as well as pH *** storage at 25°C for 60 days,freeα-amylase only retained 60%of its initial activity,while PEI/PDA-M-CLEAs and N-M-CLEAs retained 80%and 78%of their initial activities,***,N-M-CLEAs and PEI/PDA-M-CLEAs showed good *** 6 repeated uses,PEI/PDA-M-CLEAs and N-M-CLEAs still maintained 65%and 62%of their initial activities,***,PEI/PDA-M-CLEAs and N-M-CLEAs exhibited higher starch hydrolysis efficiency than freeα-*** maximum dextrose equivalent(DE)values of starch hydrolysis by PEI/PDA-M-CLEAs and N-M-CLEAs reached 29.24%and 28.79%within 90 min,***,the maximum DE values of starch hydrolysis by the freeα-amylase was only 27.89%even in 150 *** magnetic cross-linkedα-amylase aggregates could be introduced as effective biocatalyst for industrial applications in production of maltose syrups.

关键词： α-amylase Magnetic nanoparticles Functional modification Magnetic cross-linked enzyme aggregates Hydrolysis of starch

The chromosome-level reference genome assembly for Panax notoginseng and insights into ginsenoside biosynthesis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plant Communications 2021年第1期2卷 54-68页

作者： Zhouqian Jiang Lichan Tu Weifei Yang Yifeng Zhang Tianyuan Hu Baowei Ma Yun Lu xiuming cui Jie Gao Xiaoyi Wu Yuru Tong Jiawei Zhou Yadi Song Yuan Liu Nan Liu Luqi Huang Wei Gao School of Traditional Chinese Medicine Capital Medical UniversityBeijingChina School of Pharmaceutical Sciences Capital Medical UniversityBeijingChina Annoroad Gene Technology BeijingChina Faculty of Life Science and Technology Kunming University of Science and TechnologyKunmingChina State Key Laboratory Breeding Base of Dao-di Herbs National Resource Center for Chinese Materia MedicaChina Academy of Chinese Medical SciencesBeijingChina Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijingChina

Panax notoginseng,a perennial herb of the genus Panax in the family Araliaceae,has played an important role in clinical treatment in China for thousands of years because of its extensive pharmacological ***,we report a high-quality reference genome of ***,with a genome size up to 2.66 Gb and a contig N50 of 1.12 Mb,produced with third-generation PacBio sequencing *** is the first chromosome-level genome assembly for the genus *** genome evolution analysis,we explored phylogenetic and whole-genome duplication events and examined their impact on saponin *** performed a detailed transcriptional analysis of *** and explored genelevel mechanisms that regulate the formation of characteristic ***,we studied the biosynthesis and regulation of saponins at temporal and spatial *** combined multi-omics data to identify genes that encode key enzymes in the *** terpenoid biosynthetic ***,we identified five glycosyltransferase genes whose products catalyzed the formation of different ginsenosides in *** genetic information obtained in this study provides a resource for further exploration of the growth characteristics,cultivation,breeding,and saponin biosynthesis of ***.

关键词： chromosome-level genome ginsenoside P.notoginseng regulation transcriptome

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

烟碱与苯甲酸的相互作用研究

中国烟草学报 2020年第6期26卷 1-5页

作者：邬帅帆崔秀明黄艳华宝香精股份有限公司上海市201821

【目的】探究烟碱与苯甲酸是否可结合形成稳定的复合物。【方法】通过Job’s Plot方法、核磁共振氢谱(1H NMR)、红外光谱、等温滴定量热法(ITC)以及理论计算确定了两者间的相互作用方式。【结果】(1)通过Job’s Plot方法测定了烟碱与苯... 详细信息

【目的】探究烟碱与苯甲酸是否可结合形成稳定的复合物。【方法】通过Job’s Plot方法、核磁共振氢谱(1H NMR)、红外光谱、等温滴定量热法(ITC)以及理论计算确定了两者间的相互作用方式。【结果】(1)通过Job’s Plot方法测定了烟碱与苯甲酸的结合比例为1:1。(2)通过核磁共振氢谱及红外光谱确定了烟碱与苯甲酸之间存在相互作用力,确定了两者的结合方式。(3)运用等温滴定量热法再次验证了烟碱与苯甲酸的结合比例,测定了两者结合过程中的热力学数据(ΔH=-26.8 KJ/mol;ΔG=-33.99 KJ/mol;ΔS=24.12 J/mol•K)及结合常数(Ka=9.021×10^5 M^-1)。(4)通过理论计算得出两者的结合能E=-18.64 Kcal/mol。【结论】烟碱与苯甲酸之间存在较强的结合力,可以结合形成1:1的复合物,结合过程是自发的放热过程,复合物拥有更高的热解温度。

关键词：烟碱苯甲酸结合比例结合常数结合能

DALP Analysis on Genetic Diversity of <i>Panax notoginseng</i>

在线全文

学校读者我要写书评

暂无评论

Chinese Medicine 2014年第2期5卷 123-129页

作者： xiuming cui Hui Xiao Jingjing Yang Tina Dong Karl Wah-Keung Tsim Yuqin Sun Yan Zhu College of Life Science and Technology Kunming University of Science and Technology Kunming China Department of Biology and Biotechnology Research Institute The Hong Kong University of Science and Technology Hong Kong China Wenshan Sanqi Research Institute Wenshan College Wenshan China

Panax notoginseng (Burk) F.H. Chen is one of the most famous Chinese traditional medicinal plants, which belongs to Panax genus under Araliaceae family. At the present, Panax notoginseng cultivated is a mix colony. Using DALP makers, this article studied on genetic diversity of cultivated populations of Panax notoginseng in Wenshan County of Yunnan province and Napo country of Guangxi province. And the results showed that there were 260 polymorphic loci detected from the total of 292 in 13 populations, and there was great part of genetic diversity found between populations and the genetic differentiations were lower within populations. So there is broad prospect in good species breeding. And it can provide basic information for resource protection and sustainable use of Panax notoginseng.

关键词： Panax notoginseng Genetic Diversity DALP

A review on numerical studies of airflow dynamics and particle deposition in human respiratory system Author links open overlay panel

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Particuology 2024年第8期91卷 351-377页

作者： Hao Jing Xinguang cui School of Aerospace Engineering Huazhong University of Science and TechnologyWuhan430074China

Accurate assessment and prediction of airflow dynamics and particle deposition in the human respiratory tract are essential for human health,involving inhaled drugs for treating various diseases and toxic particles that can cause *** intricate process involves complex multiphase flow with distinct respiratory *** fluid dynamics(CFD)acts as a bridge,overcoming the limitations of in vivo and in vitro experiments and providing a means to fully comprehend and reveal the fundamental mechanisms of respiratory flow and particle behavior on a microscopic *** paper provides a comprehensive overview and concise summary of recent advancements in the numerical simulation of airflow and particle deposition in the human respiratory ***,it summarizes the transition of respiratory tract models from segmented models to emerging physiological characteristic models and whole-lung airway models,and the latest developments on the effects of key factors such as geometric variations,respiratory patterns,and particle physical/chemical properties on respiratory flow and particle deposition.A notable focus of this review is on emerging physiological characteristics models and their associated complex airflow and particle dynamics inside *** paper concludes with recommendations for future research to further advance the development of this field.

关键词： Airflow dynamics Particle deposition Human respiratory system Numerical modeling