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Online differential pressure reset method with adaptive adjustment algorithm for variable chilled water flow control in central air-conditioning systems

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Building Simulation 2021年第5期14卷 1407-1422页

作者： Tianyi Zhao Ying Zhou Jili Zhang xiuming li Institute of Building Energy School of Civil EngineeringFaculty of Infrastructure EngineeringDalian University of TechnologyDalian 116024China School of Metallurgy Northeastern UniversityShenyang 110819China

Central air-conditioning systems predominantly operate under partial load *** optimization of a differential pressure setpoint in the chilled water system of a central air-conditioning system leads to a more energy-efficient *** the differential pressure adjustment value based on the terminal user's real-time demand is one of the critical issues to be addressed during the optimal control ***,the online application of the differential pressure setpoint optimization method needs to be considered,along with the stability of the *** paper proposes a variable differential pressure reset method with an adaptive adjustment algorithm based on the Mamdani fuzzy *** proposed method was compared with differential pressure reset methods with reference to the chilled water differential temperature,outdoor temperature,and linear model based on the adjustment *** energy-saving potential,temperature control effect,and avoidance of the most unfavorable thermodynamic loop effects of the four methods were investigated *** results indicated that,while satisfying the terminal user's energy supply demand and ensuring the avoidance of the most unfavorable thermodynamic loop,the proposed adaptive adjustment algorithm also decreased the differential pressure setpoint value by 25.1%—59.1%and achieved energy savings of 10.6%-45.0%.By monitoring the valve position and supply air temperature of each terminal user,the proposed method exhibited suitable online adaptability and could be flexibly applied to buildings with random load changes.

关键词： central air-conditioning system variable water flow control most unfavorable thermodynamic loop differential pressure reset adaptive control

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Global hydraulic stability analysis for dynamic regulation in multi-zone variable air volume air-conditioning system

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Energy and Built Environment 2024年第4期5卷 592-606页

作者： Tianyi Zhao Zhe li xiuming li Honglian Peng Institute of Building Energy School of Civil EngineeringFaculty of Infrastructure EngineeringDalian University of TechnologyDalian 116024China Anhui Province Key Laboratory of Intelligent Building&Building Energy Saving Anhui Jianzhu UniversityHefei 230022China School of Metallurgy Northeastern UniversityShenyang 110819China School of Architecture Harbin Institute of TechnologyHarbin150006China

Variable air volume air-conditioning system(VAV system)has multiple control loops that interfered with each other,which has serious impacts on its actual operation *** solve this problem,the index of global hydraulic stability,which takes the physical quantity of the pipe network pressure and the air flow rate as reference,is proposed based on Graph theory,and a pipe network model for the hydraulic calculation is ***,the simulation study based on the actual operation data is carried out in *** distribution of the pressure and the air flow in the pipe network is obtained,and the action interferences among adjacent terminal boxes are analyzed based on global hydraulic stability under damper position regulation strategy(DP strategy)and fan frequency regulation strategy(FF strategy).Results indicate that the FF strategy can decrease the total change distance of the damper position compared with the DP strategy,and then the fluctuation of the pressure and the air flow can be *** contribution of this study is to provide an evaluation index of global hydraulic stability,which can also be used in other air-conditioning systems with multiple terminals and multiple control loops.

关键词： VAV system Global hydraulic stability Adjustment strategy VAV box damper position

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新型超声快速处理活检标本保存不同年限对DNA质量的影响

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中国组织工程研究 2025年第13期29卷 2655-2660页

作者：石晨曦朱卫东李三恩李秀明师逢丁亚云苏州大学附属第一医院病理科江苏省苏州市215000 苏州市立医院本部皮肤科江苏省苏州市215000

背景:新型超声组织处理技术越来越多地被用来进行分子生物学分析,研究新型超声处理不同存储年限组织DNA的质量,对进一步分子检测的标本质控具有重要意义。目的:探讨新型超声处理活检标本存储不同年限对DNA质量的影响,以期为分子检测探... 详细信息

背景:新型超声组织处理技术越来越多地被用来进行分子生物学分析,研究新型超声处理不同存储年限组织DNA的质量,对进一步分子检测的标本质控具有重要意义。目的:探讨新型超声处理活检标本存储不同年限对DNA质量的影响,以期为分子检测探索最佳的标本存储时间。方法:收集40例乳腺穿刺小活检组织,采用超声技术制作石蜡标本,按照存储年限分为4组:3-5年组及>5年组,每组10例,对石蜡标本进行切片,每张切片厚3μm,切片10-15张,提取DNA后通过Nanophotometer N60超微量分光光度计和Qubit 4.0荧光计检测DNA的质量浓度,记录A_(260)/A_(280)比值判定DNA的纯度,利用全自动毛细管电泳核酸分析仪(Qsep 100)检测DNA片段完整性,以评估DNA片段的质量。结果与结论:4组样本A_(260)/A_(280)均值在1.8-2.0之间,达到纯度要求,无明显差异。4组样本的DNA质量浓度(Qubit浓度)均值分别为30.39,14.33,2.52,1.95 ng/μL;DNA的平均N/Q比值分别为6.48,14.18,24.56,29.86;DNA质量数均值分别为5.64,1.76,1.24,0.80;大片段占比均值分别为56.08%,17.72%,12.68%,7.90%。PCR检测内控基因Ct均值分别为15.32,17.09,18.39,21.24。与<1年组相比,其余3组DNA浓度显著降低,N/Q比值显著增加,DNA质量数和大片段占比均值显著降低,Ct值升高,差异有显著性意义(P<0.05)。实验结果表明,对于新型超声处理活检标本,应优先选择存储<1年的样本进行日常分子检测,储存3年内的样本可满足二代测序等检测要求,5年内样本仅可尝试进行PCR等检测,存储超过5年的样本不建议进行后续分子检测。

关键词：超声处理存储年限 DNA质量片段完整性降解程度二代测序

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Interpretable data-driven fault diagnosis method for data centers with composite air conditioning system

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Building Simulation 2024年第6期17卷 965-981页

作者： Yiqi Zhang Fumin Tao Baoqi Qiu xiuming li Yixing Chen Zongwei Han SEP Key Laboratory of Eco-Industry School of MetallurgyNortheastern UniversityShenyang110819China Energy Saving and Low-carbon Technology of Process Industry Engineering Research Center of liaoning Province Northeastern UniversityShenyang110819China College of Civil Engineering Hunan UniversityChangsha410082China

Fault detection and diagnosis are essential to the air conditioning system of the data center for elevating reliability and reducing energy *** study proposed a convolutional neural network(CNN)based data-driven fault detection and diagnosis model considering temporal dependency for composite air conditioning system that is capable of cooling the high heat flux in data *** input of fault detection and diagnosis model was an unsteady dataset generated by the experimentally validated transient mathematical *** dataset concerned three typical faults,including refrigerant leakage,evaporator fan breakdown,and condenser ***,the CNN model was trained to construct a map between the input and system operating ***,the performance of the CNN model was validated by comparing it with the support vector machine and the neural ***,the score-weighted class mapping activation method was utilized to interpret model diagnosis mechanisms and to identify key input features in various operating *** results demonstrated in the pump-driven heat pipe mode,the accuracy of the CNN model was 99.14%,increasing by around 8.5%compared with the other two *** the vapor compression mode,the accuracy of the CNN model achieved 99.9%and declined the miss rate of refrigerant leakage by at least 61%*** score-weighted class mapping activation results indicated the ambient temperature and the actuator-related parameters,such as compressor frequency in vapor compression mode and condenser fan frequency in pump-driven heat pipe mode,were essential features in system fault detection and diagnosis.

关键词： data center composite air conditioning system fault detection and diagnosis interpretable artificial intelligence

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Simulation analysis for controlling temperature stability of a radiant-board system served for thermodynamic temperature measurement laboratory

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Building Simulation 2024年第9期17卷 1515-1529页

作者： Haoxue liu Siqi liu xiuming li Zongwei Han Haiyang Zhang Bo Gao liaoning Engineering Research Center of Process Industry Energy Saving and Low-carbon Technologies School of MetallurgyNortheastern UniversityShenyang110819China State Key Laboratory of Cryogenic Science and Technology Beijing100190China TIPC-LNE Joint Laboratory on Cryogenic Metrology Science and Technology Technical Institute of Physics and Chemistry(TIPC)Chinese Academy of Sciences(CAS)Beijing100190China

Fundamental metrology is closely tied to scientific advancement and requires well-equipped facilities to achieve low measurement uncertainty in rigorous *** the±0.1 K high-stability temperature control issue of the precision laboratory radiant air conditioning system,this study investigated the influence of different radiant panel area ratios,laying methods,cold source water supply temperature fluctuations,and external environmental disturbances by *** results indicate that:(1)the larger the ratio of radiant panel area,the greater the fluctuation in equipment surface temperature;(2)the surface temperature of the measurement equipment can satisfy±0.1 K control temperature stability requirement when the fluctuations of the surface temperature of radiant panels and glass window are within±0.5 K and±1 K respectively without radiant panels on the ceiling;(3)the surface temperature of the measurement equipment can satisfy±0.1 K control temperature stability requirement when the fluctuations of the surface temperature of radiant panels and glass window are within±0.2 K and±2 K respectively with radiant panels on the *** study provides a reference for the design and operation control of air conditioning systems in fundamental metrology.

关键词： metrology laboratory accurate and stable radiation air conditioning system fluent simulation

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CRISPR/Cas9 technology and its application in horticultural crops

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Horticultural Plant Journal 2022年第4期8卷 395-407页

作者： Yang liu Chunling Zhang Xiaofei Wang xiuming li Chunxiang You State Key Laboratory of Crop Biology College of Horticulture Science and EngineeringShandong Agricultural UniversityTai’anShandong 271018China

Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR associated 9(CRISPR/Cas9)system has recently become one popular technology due to its efficiency,precision,and simplicity compared with other genome editing tools such as Zinc Finger Nucleases(ZFNs)and Transcription Activator like Effector Nucleases(TALENs).Horticultural crops provide energy and health-keeping nutrients to ***-editing technology has become widely adopted in horticultural breeding with the increasing demand for high yield and better-quality horticultural ***,we describe the CRISPR/Cas9 system construction,its optimization,including sgRNA promoter,sgRNA design,Cas9 protein promoter,SpCas9 variants and orthologs,and vector delivery *** also summarized the application of this technology in horticultural plants for stress responses enhancement,fruit quality improvement,and cultivation traits *** detailed review was compiled to help establish comprehensive understanding of the CRISPR/Cas9 systems and provide a reference for further developing this technology to manipulate horticultural plant traits effectively.

关键词： Gene editing CRISPR/Cas9 technology Horticultural plant

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Genome-wide identification and functional characterization of the MdCLE peptide family in apple(Malus×domestica)

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Horticultural Plant Journal 2022年第3期8卷 279-288页

作者： Tianen Zhang xiuming li Qiang Zhao Yan Shi Yujin Hao Chunxiang You State Key Laboratory of Crop Biology College of Horticulture Science and EngineeringShandong Agricultural UniversityTaianShandong 271000China College of Horticulture Qingdao Agricultural UniversityQingdaoShandong 266109China

The CLAVATA3/EMBRYO SURROUNDING REGION-related(CLE)peptides are critical for stem cell homeostasis in plant shoot and root apical *** CLE genes have been reported in numerous plants,there is limited information for ***,twenty-five MdCLE genes were identified fromapple genome(Apple Genome V1.0 predicted peptides).Analysis of chromosomal location showed that the 25 MdCLE genes were located on 12 of 17 apple *** structure analysis showed that 21 of 25 the MdCLE genes were *** patterns showed thatmost of the MdCLE genes showed higher expression levels in leaves and root compared with the other *** addition,expression analysis demonstrated that MdCLE genes had different gene expression patterns for abiotic stress treatment,suggesting their potential roles in acclimation of apple to adverse *** 25 MdCLE genes encoded 19 different CLE peptides,and they were divided into two groups depending on their effects on the inhibition of Arabidopsis root *** results suggest that MdCLE genesmay have an important but redundant function in regulating plant growth and development,and this work provides valuable references for further investigation of the biological functions of MdCLE genes.

关键词： CLV3/ESR-related(CLE) Apple Peptide hormone Expression analysis Root growth regulation

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Lactiplantibacillus plantarum AR113 alleviates microbiota dysbiosis of tongue coating and cerebral ischemia/reperfusion injury in rat

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Food Science and Human Wellness 2024年第4期13卷 2132-2140页

作者： Zhiqiang Xiong Gang liu ling Fang xiuming li Yongjun Xia Guangqiang Wang Xin Song lianzhong Ai Shanghai Engineering Research Center of Food Microbiology School of Health Science and EngineeringUniversity of Shanghai for Science and TechnologyShanghai 200093China Department of Rehabilitation Huashan HospitalFudan UniversityShanghai 200040China Department of Rehabilitation Medicine Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China

Stroke is one of the leading causes of death and disability ***,information on stroke-related tongue coating microbiome(TCM)is limited,and whether TCM modulation could benefit for stroke prevention and rehabilitation is ***,TCM from stroke patients(SP)was characterized using molecular *** occurrence of stroke resulted in TCM dysbiosis with significantly reduced species richness and *** abundance of Prevotella,Leptotrichia,Actinomyces,Alloprevotella,Haemophilus,and TM7_[G-1]were greatly reduced,but common infection Streptococcus and Pseudomonas were remarkably ***,an antioxidative probiotic Lactiplantibacillus plantarum AR113 was used for TCM intervention in stroke rats with cerebral ischemia/reperfusion(I/R).AR113 partly restored I/R induced change of TCM and gut microbiota with significantly improved neurological deficit,relieved histopathologic change,increased activities of antioxidant enzymes,and decreased contents of oxidative stress ***,the gene expression of antioxidant-related proteins and apoptosis-related factors heme oxygenase-1(HO-1),superoxide dismutase(SOD),glutathione peroxidase(GSH-Px),nuclear factor erythroid 2-related factor 2(Nrf2),NAD(P)H:quinone oxidoreductase-1(NQO-1),and Bcl-2 was significantly increased,but cytochrome C,cleaved caspase-3,and Bax were markedly decreased in the brain by AR113 *** results suggested that AR113 could ameliorate cerebral I/R injury through antioxidation and anti-apoptosis pathways,and AR113 intervention of TCM may have the application potential for stroke prevention and control.

关键词： Stroke Cerebral ischemia/reperfusion Tongue coating Lactiplantibacillus plantarum AR113 Probiotic intervention

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HPCE法同时检测果蔬及肉制品中硝酸盐和亚硝酸盐含量

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食品科学 2018年第12期39卷 301-307页

作者：李秀明马俪珍天津农学院食品科学与生物工程学院天津300384

为了能够同时、快速检测果蔬及肉制品中的硝酸盐和亚硝酸盐,利用高效毛细管电泳对其进行检测,重点研究检测条件的筛选和干扰离子的排除。使用内径50μm、总长40 cm、有效长度30 cm的毛细管柱,在214 nm条件下,采用毛细管区带电泳-直接紫... 详细信息

为了能够同时、快速检测果蔬及肉制品中的硝酸盐和亚硝酸盐,利用高效毛细管电泳对其进行检测,重点研究检测条件的筛选和干扰离子的排除。使用内径50μm、总长40 cm、有效长度30 cm的毛细管柱,在214 nm条件下,采用毛细管区带电泳-直接紫外法,研究分离缓冲液的pH值、浓度、电渗流改性剂十六烷基三甲基溴化铵的添加量、排除Cl^-干扰方式以及分离电压对分离效果的影响,同时进行方法学检验,以确定其回收率、线性、检出限和精密度。结果表明:对于含盐量500 mmol/L以下的样品在6 min内NO_3^-和NO_2^-能够达到很好分离,该方法的加标回收率在81.82%~100.91%之间,线性范围较宽,相关系数均在0.99以上,检出限分别为0.69μg/mL和0.50μg/mL,精密度均不高于3.2%,具有简便、快速、准确、环保等优点,也为生产中快速监控硝酸盐和亚硝酸盐残留量提供了科学依据。

关键词：毛细管电泳法果蔬及肉制品硝酸盐亚硝酸盐 Cl-干扰

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Post-Ugi反应的研究进展

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有机化学 2017年第9期37卷 2237-2249页

作者：李修明贾学顺殷亮上海大学化学系上海200444 中国科学院上海有机化学研究所中科院天然产物有机合成化学重点实验室上海200032

Ugi反应是一种高效的、原子经济性的多组分反应.Post-Ugi反应作为其拓展,是多取代杂环化合物的有效合成方法,受到人们的广泛关注.综述了post-Ugi反应的发展,重点总结了近些年来的相关报道.

关键词： post-Ugi反应杂环加成偶联

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