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Graphene reinforced nanoarchitectonics of 3D interconnected magnetic-dielectric frameworks for high-efficient and anti-corrosive microwave absorbers

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Journal of Materials Science & Technology 2024年第1期168卷 194-207页

作者： Chenchen Liu Xiaofang Feng Shuning Liu Guo Lin Zhongxiang Bai Lingling wang Ke Zhu xiulan Li Xiaobo Liu School of Materials and Energy University of Electronic Science and Technology of ChinaChengdu611731China Sichuan Province Engineering Technology Research Center of Novel CN Polymeric Materials Chengdu611731China School of Chemical Engineering Northwest UniversityXi’an710069China Guangdong Provincial Key Laboratory of Environmental Pollution Control and Remediation Technology School of Environmental Science and EngineeringSun Yat-sen UniversityGuangzhou510275China

The combination of high efficiency and environmental stability is vital to promote the commercial appli-cations of microwave absorption(MA)materials,yet remains challenging in the absence of facile routes.Here,we put forward a graphene-reinforced construct approach for one-pot synthesis of 3D intercon-nected magnetic-dielectric frameworks via pre-functionalization and subsequent assembly.Multiple in-teractions among discrete precursors are capable of manipulating the confined growth and interfacial self-assembly.Significant enhancements in MA properties are triggered in a straightforward manner us-ing ultralow feeding fractions of graphene oxide nanosheet.The minimum reflection loss is up to-60.1 dB(99.9999%wave absorption)and the effective absorption bandwidth reaches 5.9 GHz(almost covering the Ku band).Remarkably,based on the optimization by ultralow concentrations of graphene,the as-prepared nanoarchitecture simultaneously integrates strong absorption,broad bandwidth,and low matching thick-ness.The embedded graphene nanosheets serve as high-speed electron transmission channels and hollow resonance cavities,facilitating multimode attenuations and impedance-matching characteristics.Mean-while,the graphene-reinforced framework suppresses the corrosion of magnetic components,whose cor-rosion rate reduces by an order of magnitude.This study provides a simple procedure to boost magnetic-dielectric absorbers for comprehensive MA performances and enhanced corrosion resistance.

关键词： 3D Magnetic-dielectric framework Graphene nanosheet Microwave absorption Anti-corrosion

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Bifidobacterium breve alleviates gut–liver-axis injury caused by high-fat diet and aflatoxin B1 in mice

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Food Science and Human Wellness 2024年

作者： Yongli Ye Tingwei wang Jian Ji Jiasheng wang Yinzhi Zhang xiulan Sun International Joint Laboratory on Food Safety Synergetic Innovation Center of Food Safety and Quality Control School of Food Science and Technology Jiangnan University School of Biological and Chemical Engineering Zhejiang University of Science and Technology Yixing Institute of Food and Biotechnology Co. Ltd. Department of Environmental Health Science College of Public Health University of Georgia

Aflatoxin B1(AFB1) is a common contaminant in cereals of global concern， and long-term low-dose exposure can adversely affect human health. Here， we showed that populations with dietary patterns characterized by high-fat diet (HFD) might have an increased risk of exposure to high levels of AFB1. Our data indicated that chronic exposure of AFB1 induced “gut-liver axis” injury in mice under HFD and normal diet (ND) patterns. AFB1 further aggravated hepatic and intestinal injury， and intestinal microbiota disruption in HFD mice. Bifidobacterium breve BAA-2849 intervention analysis showed that liver injury and lipid disorders caused by AFB1 exposure were alleviated by regulating the proportions of different gut microbes. We demonstrated through a mice model that the populations with a dietary pattern of HFD might be more susceptible to AFB1 exposure and adverse effects on the gut-liver axis， and the toxicity of AFB1 exposure can be alleviated by regulating the gut microbiota.

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Sugemule-10:Source of prescription and modern clinical application

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Chinese Herbal Medicines 2022年第3期14卷 376-384页

作者： Xiangmei Chen Liangliang Hadanbaoligao Zhang Buriebao xiulan wang Wurihan Tai Affiliated Hospital of Inner Mongolia Minzu University Tongliao 028005China NMPA Key Laboratory for Quality Control of Traditional Chinese Medicine(Mongolian Medicine) Tongliao 028000China National and Local Joint Engineering Research Center for Mongolian Medicine Research and Development(Development and Reform Commission) Tongliao 028000China Key Laboratory of Mongolian Medicine R&D Engineering Ministry of EducationTongliao 028000China Mongolian Medicine Research and Health Science Center of Inner Mongolia Minzu University Tongliao 028000China

Sugemule-10,one of the traditional Mongolian medicine(TMM)formulae,is derived from Four Medical Classics(Vol.4)and composed of 10 Mongolian medicines.It is used to treat kidney cold,low back pain,urinary obstruction,kidney/bladder stones,and is the main prescription for kidney cold.The current research on Sugemule-10 is mostly focused on its clinical efficacy,and few papers are available upon its historical changes.Therefore,we systematically reviewed Sugemule-10 from the aspects of prescription source,prescription interpretation,efficacy evolution,and modern clinical applications.

关键词： clinical application prescription interpretation prescription source Sugemule-10

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Evaluation of the Efficacy of Alanyl-Glutamine for Nutritional Support in Septicemia

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Journal of Clinical and Nursing Research 2024年第5期8卷 244-248页

作者： xiulan Hu Hongfeng Yang Chun wang Lu Bai The First People’s Hospital of Zhenjiang City Zhenjiang 212000JiangsuChina

Objective:To evaluate the therapeutic efficacy of alanyl-glutamine(Ala-Gln)in the nutritional support of sepsis.Methods:120 cases of sepsis patients admitted to the hospital in the past three years were selected and grouped by randomization method,Group A was treated with Ala-Gln,and Group B was treated with conventional nutritional support therapy,and the therapeutic effects were compared.Results:Before treatment,there was no difference in nutritional indexes,immune function indexes,and inflammatory factors between the two groups(P>0.05).After treatment,the nutritional indexes of Group A were higher than those of Group B,the immune function indexes were higher than those of Group B,and the inflammatory factors were lower than those of Group B(P<0.05).Except for mortality,the regression of group A was better than that of group B(P<0.05).Conclusion:Ala-Gln can improve the nutritional indexes of septicemia patients during the treatment period,enhance their immune function,reduce the inflammatory response of the body,and promote the regression of the disease.

关键词： Alanyl-glutamine Sepsis Nutritional support Immune function index Regression

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The Stable Behavior of the Augmentation Quotients of the Groups of Order p^5, I

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Algebra Colloquium 2016年第2期23卷 189-204页

作者： xiulan wang Department of Mathematics Harbin Institute of Technology Harbin 150001 China

In this article we describe the stable behavior of the augmentation quotients Qn （G） for the groups G of order p^5 with even numbers of generators, where p is an odd prime.

关键词： integral group ring augmentation quotient group stable behavior

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Early Nursing Intervention in Children with Viral Meningitis

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Journal of Behavioral and Brain Science 2024年第1期14卷 1-11页

作者： Jingyan wang Qiuyan Peng Haomei Yang Jing Sun Xian Cai xiulan Wen Congqun Li Yan Lin Xuan Shi Pediatric Emergency Department Guangzhou Women and Children’s Medical Center Guangzhou Medical University Guangzhou China

Aim: To explore the effect of a WeChat peer education program in children with severe viral meningitis combined with respiratory failure. Design: Retrospective cohort study. Methods: Patients who had severe viral meningitis combined with respiratory failure, were admitted to the hospital from March 2017 to June 2018, and who received the WeChat-based nursing intervention were included. Patients who received routine nursing were used as controls. The family’s emotional state, self-care ability, and rehabilitation were analyzed. Results: There were 37 patients in the WeChat group (19 boys (51.3%) and 18 girls (48.7%);mean of 5.1 ± 2.4 years of age) and 37 controls (20 boys (54.1%) and 17 girls (45.9%);mean of 5.9 ± 2.4 years of age) (all P > 0.05). After nursing, improvements in the self-assessed anxiety score and self-assessed depression score were better in the WeChat group (anxiety: -29.2% vs. -20.3%, P = 0.015;depression: -25.2% vs. -15.4%, P = 0.009). After nursing, the improvements in the condition management ability scale and condition management difficulty scale scores were better in the WeChat group (ability: +80.5% vs. +44.4%. P = 0.001;difficulty: +58.4% vs. +37.8%, P = 0.003). After nursing, the improvement in the Fugl-Meyer score was better in the WeChat group (+138.0% vs. +53.0%, P Conclusion: Early nursing intervention combined with WeChat peer education can improve the emotional state of children with severe viral meningitis combined with respiratory failure and their caregivers. Impact: Viral meningitis is associated with a good prognosis, but central nervous system complications can be observed. Early intervention is the key to a good prognosis. Internet-based nursing and coaching can improve self-efficacy and care ability in patients with various conditions, as well as improve the emotional state of the children and their caregivers. The research might have an impact on any children’s hospital that deals with viral meningitis.

关键词： Societies Nursing Early Intervention Educational Meningitis Viral Child

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老年性聋发病机制研究进展

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听力学及言语疾病杂志 2024年第1期32卷 80-84页

作者：王松韩贺舟马秀岚中国医科大学附属盛京医院耳鼻咽喉头颈外科沈阳110004

老年性聋是以隐匿性、缓慢进行性双侧感音神经性听力下降为特征的疾病,其发生和发展是一个多因素作用的过程,每种因素的作用在个体间差异较大。针对老年性聋的发病机制,目前已有一定研究,主要可分为离子通道异常、耳蜗突触病变、活性氧... 详细信息

老年性聋是以隐匿性、缓慢进行性双侧感音神经性听力下降为特征的疾病,其发生和发展是一个多因素作用的过程,每种因素的作用在个体间差异较大。针对老年性聋的发病机制,目前已有一定研究,主要可分为离子通道异常、耳蜗突触病变、活性氧自由基、激素作用、线粒体异常、遗传因素等诸多方面,本文对近年来老年性聋发病机制进行总结。

关键词：老年性聋年龄相关性听力损失发病机制

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纳米抗体筛选技术研究进展

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生物工程学报 2024年第2期40卷 350-366页

作者：唐秀兰邓安琦陈文聪赵妍王茂鹏李昌温州大学病毒学研究所温州市病毒学与免疫学重点实验室浙江温州325035 温州市农产品检验测试中心浙江温州325299 中国农业科学院长春兽医研究所吉林长春130122

纳米抗体(nanobody,Nb)是在骆驼科血清中发现的一种新型抗体,具有体积小、特异性强、稳定性高、易于表达和能识别隐藏的抗原表位等优势,在各个领域具有广泛的应用价值。本文介绍了纳米抗体筛选与优化过程,包括纳米抗体文库构建、体外展... 详细信息

纳米抗体(nanobody,Nb)是在骆驼科血清中发现的一种新型抗体,具有体积小、特异性强、稳定性高、易于表达和能识别隐藏的抗原表位等优势,在各个领域具有广泛的应用价值。本文介绍了纳米抗体筛选与优化过程,包括纳米抗体文库构建、体外展示和亲和力成熟3个重要技术阶段的分类与特点。其中,简要描述了天然、免疫及半合成/合成文库的制备方法与重要参数,并系统介绍了应用噬菌体、酵母、细菌、核糖体/mRNA和真核细胞等表面展示系统,以及酵母双杂交、高通量测序和质谱鉴定方法,共8种不同体外展示技术进行快速筛选的方法及其优缺点,汇总用于提升纳米抗体功能可靠性的体外及计算机辅助亲和力成熟技术平台,为综合运用各种技术手段快速获得稳定、可靠、特异的纳米抗体类药物或诊断制剂提供了参考。

关键词：纳米抗体体外展示筛选亲和力成熟

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医院污水中噬菌体的分布研究

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中华预防医学杂志 2024年第2期58卷 241-247页

作者：鲁鉴英潘宏伟孙恩华李伟王洪星赵秀兰王洪春山东大学公共卫生学院济南250012 山东大学齐鲁医院检验科生物标志物与人工智能应用山东省工程研究中心济南250012

噬菌体疗法是治疗多重耐药菌感染的重要手段之一。这类噬菌体通常从医院污水中分离得到,然而迄今为止对医院污水中噬菌体的分布情况尚无系统研究。本研究旨在以临床分离的常见病原菌为宿主,分离其对应的噬菌体,以此评估医院污水中噬菌... 详细信息

噬菌体疗法是治疗多重耐药菌感染的重要手段之一。这类噬菌体通常从医院污水中分离得到,然而迄今为止对医院污水中噬菌体的分布情况尚无系统研究。本研究旨在以临床分离的常见病原菌为宿主,分离其对应的噬菌体,以此评估医院污水中噬菌体的生态分布情况,并为临床耐药菌噬菌体的分离和应用提供参考。本研究采用横断面研究设计,选择2023年5—6月山东大学齐鲁医院临床微生物实验室分离得到的125株病原菌(分属于16个不同的菌种)作为目标菌株,利用双层平板夹心法从医院污水中分离纯化这些菌株对应的噬菌体。同时,借助宏基因组二代测序技术(mNGS)分析同批次污水中病原菌的分布情况,初步探究污水中病原菌与噬菌体之间的丰度对应关系。结果显示,以125株临床病原菌为宿主,共分离获得56株噬菌体,分别对应鲍曼不动杆菌、肺炎克雷伯菌、大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌、嗜麦芽窄食单胞菌等6种病原菌。这6种病原菌均包含了不同耐药程度的菌株,其中鲍曼不动杆菌、大肠埃希菌和铜绿假单胞菌中多重耐药菌株占比较高。这6种病原菌的噬菌体获得率由高到低依次为:大肠埃希菌(80%)、嗜麦芽窄食单胞菌(75%)、铜绿假单胞菌(70%)、肺炎克雷伯菌(66.67%)、鲍曼不动杆菌(36.36%)和金黄色葡萄球菌(12.5%)。初步的mNGS测序结果显示,在该批次污水中,丰度较高的病原菌分别为屎肠球菌、肺炎克雷伯菌、大肠埃希菌、粪肠球菌、鲍曼不动杆菌、产气克雷伯菌、密歇根克雷伯菌和铜绿假单胞菌。综上,医院污水中可分离到大多数临床常见革兰阴性病原菌的噬菌体,且分离率较高;然而革兰阳性病原菌的噬菌体分离率较低,在本研究中仅分离到与金黄色葡萄球菌对应的噬菌体。对应的mNGS测序结果表明革兰阴性病原菌在污水中的分布与噬菌体的生态分布可能具有一定的正相关关系。

关键词：多重耐药菌医院污水噬菌体

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四川地区甜樱桃S基因型及SFB4'基因的分子鉴定

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福建农业学报 2024年第4期39卷 418-426页

作者：张号楠李沛华梁东王进吕秀兰四川农业大学园艺学院

【目的】甜樱桃（Cerasus avium L.）的S基因决定其自交的亲和性。为鉴定四川地区甜樱桃品种的S基因型和高自交亲和性品种，本研究对收集到的39份甜樱桃材料进行S基因型鉴定，并比较SFB4与其自交亲和突变体SFB4'基因的差异。【方法】利... 详细信息

【目的】甜樱桃（Cerasus avium L.）的S基因决定其自交的亲和性。为鉴定四川地区甜樱桃品种的S基因型和高自交亲和性品种，本研究对收集到的39份甜樱桃材料进行S基因型鉴定，并比较SFB4与其自交亲和突变体SFB4'基因的差异。【方法】利用S基因通用引物和特异引物对四川地区种植的39份甜樱桃叶片DNA进行PCR扩增，并对含有SFB4/SFB4'基因的扩增片段进行测序。【结果】39份甜樱桃材料共鉴定出S1、S2、S3、S4、S6、S9等6个基因型，其中27份材料含有S3基因，19份材料含有S9基因，12份材料含有S1基因，11份材料含有S4基因，7份材料含有S6基因，3份材料含有S2基因。根据鉴定得到的S基因型结果，扩增得到含有S4基因的11份材料中的SFB基因的ORF序列，比对结果显示，相比于SFB4,SFB4'在903 bp处存在4个碱基缺失；本研究设计了SFB4'特异引物，测序结果显示，有7份材料的SFB基因型为SFB4'。【结论】共鉴定得到S1、S2、S3、S4、S6、S9等6个基因型，对含有S4基因的11份材料的S4基因全长进行测序，确定7份材料为突变基因SFB4'。本研究为四川地区甜樱桃授粉树配置提供了数据支撑，并为甜樱桃新品种的选育奠定了理论基础。

关键词：甜樱桃自交亲和性 S-RNase SFB

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