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Science China(Technological Sciences) 2010年第11期53卷 2905-2913页

作者： XiMei Tian ZhiWu Han xiujuan li ZhaoGuo Pu LuQuan Ren Jilin Univ Minist Educ Key Lab Bion Engn Changchun 130022 Peoples R China

Molluscan shells are fascinating examples of highly ordered hierarchical structure and complex organic-inorganic biocomposite material. However, their anti-wear properties were rarely studied especially in the perspective of biological coupling. So in the current study three typical shells, Scapharca subcrenata, Rapana venosa and Acanthochiton rubrolineatus, were selected as coupling models to further study their anti-wear properties. Stereomicroscope and scanning electron microscopic observations showed that all these three shells had specific surface morphologies and complicated section microstructures. Importantly, a special structure, pore canal tubules, was discovered in the shells of Scapharca subcrenata and Acanthochiton rubrolineatus, which probably contributed most to their anti-wear properties. X-ray diffraction and micro-Vikers hardness tester were further adopted to analyze the phase compositions and micro-hardness of the shells. The measured results demonstrated that aragonite was the most extensive phase present in the shell, and possesed a relatively high micro-hardness. In this paper, the shells were described in details in morphology, structure and material with emphasis on the relationship with anti-wear property. The study revealed that the selected seashells possess distinct anti-wear properties by complicated mechanisms involving the integrated functions of multiple biological coupling elements, and this would provide inspiration to the design of new bionic wear resistance components.

关键词： molluscan shell wear resistance bionic biological coupling coupling element

Cold-induced retrotransposition of fish liNEs

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Journal of Genetics and Genomics 2017年第8期44卷 385-394页

作者： Shue Chen Mengchao Yu Xu Chu Wenhao li xiujuan Yin liangbiao Chen Qingdao National Laboratory for Marine Science and Technology Qingdao 266237 China

Classes of retrotransposons constitute a large portion of metazoan genome. There have been cases re- ported that genomic abundance of retrotransposons is correlated with the severity of low environmental temperatures. However, the molecular mechanisms underlying such correlation are unknown. We show here by cell transfection assays that retrotransposition （RTP） of a long interspersed nuclear element （liNE） from an Antarctic nototbenioid fish Dissostichus mawsoni （droLl） could be activated by low temperature exposure, causing increased dmLl copies in the host cell genome. The cold-induced droll propagation was demonstrated to be mediated by the mitogen-activated protein kinases （MAPK）]p38 signaling pathway, which is activated by accumulation of reactive oxygen species （ROS） in cold-stressed conditions. Surprisingly, droLl transfected cells showed an increase in the number of viable cells after prolonged cold exposures than non-transfected cells. Features of cold inducibility of dmLl were reca- pitulated in liNEs of zebrafish origin both in cultured cell lines and tissues, suggesting existence of a common cold-induced liNE amplification in fishes. The findings reveal an important function of liNEs in temperature adaptation and provid insights into the MAPK/p38 stress responsive pathway that shapes liNE composition in fishes facing cold stresses. Copyright 2017, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, and Genetics Society of China. Published by Elsevier limited and Science Press. All rights reserved.

关键词： RetrotransposonROSp38Cold adaptationliNE amplification

Preparation of hybridizing zeolitic imidazolate frameworks with carboxymethylcellulose for adsorption separation of n-hexane/3-methylpentane

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Chinese Journal of Chemical Engineering 2021年第1期34卷 103-109页

作者： xiujuan li Le Chen Dandan Zhu Song Yang Zhong Wu Mingyang He Zhihui Zhang Qun Chen Jiangsu Key Laboratory of Advanced CatalyticMaterials and Technology Advanced Catalysis and Green Manufacturing Collaborative Innovation CenterChangzhou UniversityChangzhou 213164China

A novel ZIF-8-CMC hybrid material was fabricated from the hybridization of ZIF-8 and carboxymethylcellulose(CMC) by impregnation method for n-hexane/3-methylpentane *** surface properties of ZIF-8 were tailored by introducing CMC into ZIF-8 *** this work,adsorption separation of n-hexane(nHEX) and 3-methylpentane(3 MP) on ZIF-8-CMC were investigated by batch vapor-phase adsorption and liquid-phase breakthrough *** adsorption selectivity of nHEX/3 MP reversed from preferable adsorption of nHEX to preferable adsorption of 3 MP upon the increasing of CMC containing in the hybrid *** the temperature increases,the adsorption amounts of nHEX and 3 MP *** the increasing of CMC contents,the nHEX uptake decreased,the uptake capacity of 3 MP increased *** liquid-phase breakthrough adsorption,the dynamic adsorption capacity of nHEX also decreased with the increasing of temperature.

关键词： Zeolitic imidazolate frameworks Carboxymethylcellulose(CMC) n-Hexane Adsorption separation

Effects of Bionic Units in Different Scales on the Wear Behavior of Bionic Impregnated Diamond Bits

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Journal of Bionic Engineering 2016年第4期13卷 659-668页

作者： Zhaozhi Wang Ke Gao Youhong Sun Zhihui Zhang Shiyu Zhang Yunhong liang xiujuan li Luquan Ren Key Laboratory of Bionic Engineering (Ministry of Education China) Jilin University Changchun 130022 China College of Biological and Agrieultural Engineering Jilin University Changehun 130022 China College of Construction Engineering Jilin University Changchun 130026 China

Based on anti-wear theory of soil animals, the samples of impregnated diamond bit with bionic self-regenerated non-smooth surface were designed and fabricated. Such a bionic surface was characterized by concave-shape units of different scales that continuously maintained their shape and function during the whole working process. Abrasion tests were carried out to investigate the performance of samples. Results showed that the bionic samples exhibit excellent wear resistance and drilling performance under the action of bionic self-regenerated units, especially those with units of 2 mm - 3 mm diameter. The par- ticle-trapping mechanism coming from the self-regenerated concaves and the lubricating mechanism coming from the con- tinuously self-supplying of solid lubricant are important reasons for reducing or even avoiding the severe abrasions. The im- proved drilling performance of bionic samples derives from, on the one hand, the back edge of bionic unit that contributes to exposing new diamond and supplying additional shear stresses to increase the cutting ability, on the other hand, the enhanced load per unit area due to the decreased contact area at the frictional interface. The relationship between the wear behavior and the scale of bionic unit was revealed. The unit of smaller scale on the bionic samples can enhance the shear stress level. Further reducing the scale to a contain extent will diminish the wear resistance of sample. While increasing the scale can lead to the poor lubricating effect.

关键词： bionic non-smooth surface scale of bionic units impregnated diamond bits wear behavior

Supramolecular-mediated ball-in-ball porous carbon nanospheres for ultrafast energy storage

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InfoMat 2022年第4期4卷 112-123页

作者： Lei Yao Junsheng lin Yuanyuan Chen xiujuan li Dongrui Wang Haitao Yang libo Deng Zijian Zheng College of Materials Science and Engineering Shenzhen UniversityShenzhenP.R.China Laboratory for Advanced Interfacial Materials and Devices Institute of Textiles and ClothingThe Hong Kong Polytechnic UniversityHong Kong SARChina College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhenP.R.China

Hierarchical porous carbons are the most viable electrode material for supercapacitors because of their balanced capacitive performance and chemical *** pore connectivity plays a pivotal role in electrolyte transport,which is quantified by a new parameter,defined in this work as the longest possible pore separation(LPPS).Herein,we report hierarchical porous carbon nanospheres(HPC-NS)with a unique ball-in-ball structure,which is achieved by the pyrolysis of a supramolecular complex ofγ-cyclodextrin(γ-CD)/PEO-PPO-PEO(F127).This approach differs from the conventional softtemplating method in that,apart from the assembly of the monomicelles that leads to the host nanospheres(approximately 300 nm),theγ-CD-containing monomicelles themselves are converted to small porous carbon nanospheres(livers a high specific capacitance(405 F g^(-1)at 1 A g^(-1)and 71%capacitance retention at 200 A g^(-1)),wide voltage window(up to 1.6 V),and simultaneously high energy and power densities(24.3 Wh kg^(-1)at a power density of 151 W kg^(-1)and 9 Wh kg^(-1)at 105 W kg^(-1))in aqueous *** new strategy boosts the development of porous carbon electrodes for aqueous supercapacitors with simultaneously high power and energy densities.

关键词： hierarchical porous carbon pore connectivity supramolecular ultrafast energy storage

Tprn is essential for the integrity of stereociliary rootlet in cochlear hair cells in mice

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Frontiers of Medicine 2019年第6期13卷 690-704页

作者： Yuqin Men xiujuan li Hailong Tu Aizhen Zhang Xiaolong Fu Zhishuo Wang Yecheng Jin Congzhe Hou Tingting Zhang Sen Zhang Yichen Zhou Boqin li Jianfeng li Xiaoyang Sun Haibo Wang Jiangang Gao School of life Science Shandong UniversityJinan 250100China Rizhao Polytechnic Rizhao 276826China The Second Hospital of Shandong University Jinan 250033China Electron Microscopy Laboratory Shandong Institute of OtolaryngologyJinan 250022China Laboratory of Electron Microscopy Jinan WEI-YA Biotech CompanyJinan 250100China Department of Otolaryngology-Head and Neck Surgery Provincial Hospital Affiliated to Shandong UniversityJinan 250021China

Tprn encodes the taperin protein,which is concentrated in the tapered region of hair cell stereocilia in the inner *** humans,TPRN mutations cause autosomal recessive nonsyndromic deafness(DFNB79)by an unknown *** determine the role of Tprn in hearing,we generated Tprn-null mice by clustered regularly interspaced short palindromic repeat/Cas9 genome-editing technology from a CBA/CaJ *** observed significant hearing loss and progressive degeneration of stereocilia in the outer hair cells of Tprn-null mice starting from postnatal day *** electron microscopy images of stereociliary bundles in the mutant mice showed some stereociliary rootlets with curved *** central cores of the stereociliary rootlets possessed hollow structures with surrounding loose peripheral dense ***,a protein expressed at stereocilia tapering,was abnormally dispersed along the stereocilia shafts in Tprn-null *** expression levels of radixin andβ-actin significantly *** propose that Tprn is critical to the retention of the integrity of the stereociliary *** of Tprn in Tprn-null mice caused the disruption of the stereociliary rootlet,which resulted in damage to stereociliary bundles and hearing *** generated Tprn-null mice are ideal models of human hereditary deafness DFNB79.

关键词： TPRN stereocilia stereociliary rootlet actin filament CRISPR/Cas9 hearing

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中药学专业第二课堂协同育人的设计与实施

卫生职业教育 2025年第1期43卷 20-23页

作者：陈少珍肖亚聪李秀娟陈静敏吕威潘美华广东岭南职业技术学院广东清远511510

探讨中药学专业第二课堂协同育人的设计与实施路径,将立德树人、工匠精神、创新创业教育等相关内容融入第二课堂建设中,以增强第二课堂协同育人效果,培养高素质技术技能型中医药人才。

关键词：中药学专业第二课堂协同育人

维普期刊数据库博看期刊

Study of the Protection System for LHCD on the HL-2A Tokamak

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Southwestern Institute of Physics Annual Report

Southwestern Institute of Physics Annual Report 2004年第1期 70-73页

作者： li xiujuan WANG Mingwei SONG Shaodong

LHCD experiment has been carried through in HL-1M tokamak since 1995, and the work is successful. This years the LHCD experiment would go ahead on the HL-2A tokamak that had been improved from HL-1M system.

关键词： Arc Body-current Over-current

THE QUADRATIC SYSTEM WITH NONHYPERBOliC HOMOCliNIC CYCLE

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Annals of Differential Equations 2005年第3期21卷 403-406页

作者： Song xiujuan Zheng Yanhong li Xuepeng Dept. of Math. Fujian Normal University Fuzhou 350007

In this paper, we will show some sufficient conditions to assert certain system existing nonhyperbolic homoclinic cycles.

关键词： quadratic systems nonbyperbolic homoclinic cycles lie group

Temporal and Spatial Evolution of Lakes in the Bashang Plateau for Nearly Recent 30 Years

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Journal of Water Resource and Protection 2022年第10期14卷 698-708页

作者： xiujuan li Sugai Gao Wenli li Guifu Qiu Zhiyuan Tian Department of Resources and Environmental Engineering Shandong Agriculture and Engineering University Jinan China Beijing Yanqing District No.1 Middle School Beijing China Zhangjiakou Saibei Forestry Centre Zhangjiakou China Kangbao County Natural Resources and Planning Bureau Zhangjiakou China

Lakes are important ecological water sources in the Bashang Plateau. Its expansion or shrinkage directly affects the ecological security of the plateau and its surrounding areas. In this study, Landsat images from 1984 to 2015 were selected to monitor the area of lakes in the Bashang Plateau and to analyze the spatiotemporal evolution and driving forces of lakes in the Bashang Plateau. The results showed that there were 47 lakes in the Bashang Plateau in 2015, with a total area of 37.63 km2, mainly distributed in the central and western regions of the region. From 1984 to 2015, the lakes in Bashang Plateau showed a shrinking trend. At the same time, there are obvious stage differences in lake changes. During 1984-1996, the number of lakes increased by 99 and the total area increased by 124.43 km2. From 1996 to 2015, the number of lakes decreased by 142, and the total area decreased by 183.96 km2. Before 1996, climate change was the dominant factor. However, the shrinkage of lakes after 1996 is the result of climate change and human activities. Among them, the large-scale planting of water consuming crops such as vegetables is the main human activity mode leading to lake shrinkage. This study will help to understand the expansion and contraction factors of the Bashang Plateau lakes in Hebei province and provide a reference for the future protection and management of the lakes.

关键词： Bashang Plateau Lake Area Spatial and Temporal Patterns Evolution Driving Force