检索结果-南通市图书馆

Neutralizing antibodies for the prevention and treatment of COVID-19

在线全文

学校读者我要写书评

暂无评论

Cellular & Molecular Immunology 2021年第10期18卷 2293-2306页

作者： Lanying Du Yang Yang xiujuan zhang Lindsley F.Kimball Research Institute New York Blood CenterNew YorkNYUSA Roy J.Carver Department of Biochemistry Biophysics and Molecular BiologyIowa State UniversityAmesIAUSA

Severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)initiates the infection process by binding to the viral cellular receptor angiotensin-converting enzyme 2 through the receptor-binding domain(RBD)in the S1 subunit of the viral spike(S)*** event is followed by virus–cell membrane fusion mediated by the S2 subunit,which allows virus entry into the host ***,the SARS-CoV-2 S protein is a key therapeutic target,and prevention and treatment of coronavirus disease 2019(COVID-19)have focused on the development of neutralizing monoclonal antibodies(nAbs)that target this *** this review,we summarize the nAbs targeting SARS-CoV-2 proteins that have been developed to date,with a focus on the N-terminal domain and RBD of the S *** also describe the roles that binding affinity,neutralizing activity,and protection provided by these nAbs play in the prevention and treatment of COVID-19 and discuss the potential to improve nAb efficiency against multiple SARSCoV-2 *** review provides important information for the development of effective nAbs with broad-spectrum activity against current and future SARS-CoV-2 strains.

关键词： SARS-CoV-2 Spike protein Neutralization Monoclonal antibodies COVID-19

High-mobility air-stable n-type field-effect transistors based on large-area solution-processed organic single- crystal arrays

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2018年第2期11卷 882-891页

作者： Liang Wang xiujuan zhang Gaole Dai Wei Deng Jiansheng Jie Xiaohong zhang Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices Soochow University Suzhou China

Solution-processed n-type organic semiconductor micro/nanocrystals （OSMCs） are fundamental elements for developing low-cost, large-area, and all organic logic/complementary circuits. However, the development of air-stable, highly aligned n-channel OSMC arrays for realizing high-performance devices lags far behind their p-channel counterparts. Herein, we present a simple one-step slope-coating method for the large-scale, solution-processed fabrication of highly aligned, air-stable, n-channel ribbon-shaped single-crystalline N,N＇-bis（2- phenylethyl）-perylene-3,4：9,10-tetracarboxylic diimide （BPE-PTCDI） arrays. The slope and pattemed photoresist （PR） stripes on the substrate are found to be crucial for the formation of large-area submicron ribbon arrays. The width and thickness of the BPE-PTCDI submicron ribbons can be finely tuned by controlling the solution concentration as well as the slope angle. The resulting BPE-PTCDI submicron ribbon arrays possess an optimum electron mobility up to 2.67 cm2.V-l.s-1 （with an average mobility of 1.13 cm2.V-l-s-1）, which is remarkably higher than that of thin film counterparts and better than the performance reported previously for single-crystalline BPE-PTCDI-based devices. Moreover, the devices exhibit robust air stability and remain stable after exposing in air over 50 days. Our study facilitates the development of air-stable, n-channel organic field-effect transistors （OFETs） and paves the way towards the fabrication of high-performance, organic single crystal-based integrated circuits.

关键词： n-type organic singlecrystals submicron ribbon arrays slope-coating method air-stable organic field-effecttransistors

Few-layer fbrmamidinium lead bromide nanoplatelets for ultrapuregreen and high-efficiency light-emitting diodes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2019年第1期12卷 171-176页

作者： Huan Fang Wei Deng xiujuan zhang Xiuzhen Xu Meng zhang Jiansheng Jie Xiaohong zhang Institute of Functional Nano&Soft Materials(FUNSOM) Collaborative Innovation Center of Suzhou Nano Science and Technology(NANO-CIC)Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123China

Formamidinium lead bromide perovskite(FAPbBr3)nanocrystals have attracted increasing attention due to their greener photoluminescence(PL)and higher thermal stability in comparison to more popular methylammonium lead bromide perovskite(MAPbBr3).Here we proposed a-facile and highly reproducible room-temperature method for the preparation of fewlayer(1-4)two-dimensional(2D)FAPbBr3 nanoplatelets(NPs)with ultrapure green PL at 532 nm and high photoluminescence quantum yield(PLQY)of 88%.High-efficiency ultrapure green light-emitting diodes(LEDs)based on the few-layer 2D FAPbBr3 NPs were further *** LEDs showed a maximum current efficiency(CE)of 15.31cd/A and an external quantum efficiency(EQE)of 3.53%,which are significantly better than the FAPbBr3 polycrystalline film-based LEDs reported so ***,the 2D FAPbBr3 NPs-based LEDs exhibited an ultrapure-green color emission that could cover 97%of the Recommendation 2020(Rec.2020)color standard and 114%of the national television system committee(NTSC)standard in the CIE 1931 color ***,the devices possessed a much better stability than the MAPbBr3 nanocrystals-based LEDs in air;the half lifetime T50 of our devices was about 5 times Ion ger than that of MAPbBr3 nan ocrystals-based *** work demonstrates the great potential of FAPbBr3 NPs in light-emitting devices for future ultrahigh-resolution displays.

关键词： formamidinium lead bromide perovskite few-layer nanoplatelets high-efficiency light-emitting diodes ultrapure-green electroluminescence

Short review on liquid membrane technology and their applications in biochemical engineering

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2022年第9期35卷 21-33页

作者： Wenjun zhang Wenshu Ge Min Li Shuangqing Li Minqiang Jiang xiujuan zhang Gaohong He State Key Laboratory of Fine Chemicals Dalian University of TechnologyDalian 116023China School of Chemical Engineering Dalian University of TechnologyPanjin 124221China

As a branch of membrane separation technology,liquid membrane has attracted great attention and expanded investigations in biological chemical engineering,with life and health concern in *** of membrane solvent and mobile carrier,liquid membrane was acquired of function,performing the facilitated mass transfer across the diffusive solvent,so as for the separation and delivery achievement with *** this review,two types of liquid membrane are mainly focused,respectively on supported liquid membrane(SLM)of membrane solvent supporter in necessity,and on emulsion liquid membrane(ELM)of the required interfacial stabilizers and ***,the transfer mechanism,compositions,structure and features of SLM and ELM are introduced ***,the current investigations of liquid membrane have been discussed,focusing on the improvements of efficacy and stability in separation&detection,encapsulation and delivery,so as to scale up the favorable and efficient application with bio-life ***,this review could provide comprehensive insight into the bio-applications of liquid membrane,and guidelines for the further investigations on the efficacy and long-term applicable stability,in order to realize the industrialization.

关键词： Liquid membrane Membrane separation Membrane encapsulation Delivery vehicle Bio-application

Perspective:Acoustic Metamaterials in Future Engineering

在线全文

学校读者我要写书评

暂无评论

Engineering 2022年第10期17卷 22-30页

作者： Qiangbing Lu Xin Li xiujuan zhang Minghui Lu Yanfeng Chen National Laboratory of Solid State Microstructures&Department of Materials Science and Engineering Nanjing UniversityNanjing 210093China Jiangsu Key Laboratory of Artificial Functional Materials Nanjing UniversityNanjing 210093China Collaborative Innovation Center of Advanced Microstructures Nanjing UniversityNanjing 210093China

Acoustic metamaterials(AMMs)are a type of artificial materials that make use of appropriate structural designs and exhibit exotic properties not found in natural materials,such as negative effective material parameters(e.g.,bulk modulus,mass density,and refractive index).These interesting properties offer novel means for sound manipulation and thus have drawn a great deal of *** the past two decades,tremendous progress has been made in the fundamental research of AMMs,which has not only promoted the development of modern acoustics but also shown the potential of AMMs for engineering ***,we review recent developments in AMMs with a focus on their future engineering,especially in the most promising fields of sound absorption/isolation,acoustic imaging,cloaking,and so on,furthermore,we outline the opportunities and challenges they are encountering.

关键词： Acoustic metamaterials Sound absorption/isolation Acoustic imaging Engineering application

Unusual hexa-nuclear cadmium cluster functionalized phosphomolybdate as effective photoelectrochemical sensor for trace Cr(Ⅵ)detection

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2022年第9期33卷 4400-4404页

作者： Wenting An xiujuan zhang Jiaqi Niu Yuanyuan Ma zhangang Han Hebei Key Laboratory of Organic Functional Molecules National Demonstration Center for Experimental Chemistry EducationCollege of Chemistry and Materials ScienceHebei Normal UniversityShijiazhuang 050024China

Photo-assisted electrochemical technique provides a promising approach towards carcinogen chromium(Ⅵ)detection,which requires reasonable catalyst ***,an unusual hexa-nuclear cadmium cluster functionalized reductive phosphomolybdate hybrid as photo-electrochemical sensor was designed and synthesized with formula of{[Cd(H_(2)O)_(2)]_(2)[Cd(btmbp)]_(2)}{Cd(P_(4)Mo_(6)O_(31)H_(7))_(2)}·20H_(2)O(1)(btmbp=4,4′-bis((^(1)H-1,2,4-triazol-1-yl)methyl)biphenyl),in which the photoactive hexa-nuclear{Cd_(6)}clusters cooperated with reductive phosphomolybdate[P_(4)Mo_(6)O_(31)]^(12)−endow the material with wide light absorption and remarkable redox activity,thus achieving efficient photo-assisted electrochemical Cr(Ⅵ)detection *** visible-light assistance,the detection limit(LOD)and sensitivity of Cr(Ⅵ)is 4.17 nmol/L(0.225 ppb)and 226.32μA L/μmol,which is apparently superior to the performance without photo-assistance(6.25 nmol/L and 106.95μA L/μmol)and far satisfies the demands of world health organization(WHO)for potable water(50 ppb).Moreover,compound 1 showed prominent Cr(Ⅵ)detection performance in practical water samples together with remarkable anti-interference capacity and good electrochemical *** work provides an important guidance for designing efficient polyoxometalate-based crystalline sensors for Cr(Ⅵ)detection.

关键词： Phosphomolybdate Cadmium cluster Photoelectrocatalysis Electrochemical detection Hexavalent chromium

Phase separation time/temperature dependence of thermoplastics-modified thermosetting systems

在线全文

学校读者我要写书评

暂无评论

Frontiers of Chemical Science and Engineering 2008年第3期2卷 276-285页

作者： xiujuan zhang Xiaosu YI Yuanze XU The Key Laboratory of Molecular Engineering of Polymers Ministry of EducationDepartment of Macromolecular ScienceFudan UniversityShanghai 200433China Institute Aeronautic Materials Beijing 100095China

The cure-induced phase separation processes of various thermoplastics(TP)-modified thermosetting systems which show upper critical solution temperature(UCST)or lower critical solution temperature(LCST)were studied with emphasis on the temperature dependency of the phase separation time and its potential application in the cure time-temperature processing *** found that the phase separation time/temperature relationship follows the simple Arrhenius *** cure-induced phase separation activation energy E_(a)(ps)generated from the linear fitting of the Arrhenius equation is irrelevant to the detection means of phase separation *** also found that E_(a)(ps)is insensitive to TP content,TP molecular weight and curing rate,but it changes with the cure reaction kinetics and the chemical environment of the *** the established phase separation time-temperature dependence relation,we can easily establish the whole cure time-temperature transformation(TTT)diagram with morphology information which is a useful map for the TP/TS composites processing industry.

关键词： polymerization induced phase separation thermosetting thermoplastic time and temperature dependence Arrhenius equation TTT diagram

Controlled 2D growth of organic semiconductor crystals by suppressing “coffee-ring” effect

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2020年第9期13卷 2478-2484页

作者： Wei Wang Bei Lu Wei Deng xiujuan zhang Zhengjun Lu Di Wu Jiansheng Jie Xiaohong zhang Institute of Functional Nano&Soft Materials(FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesSoochow UniversitySuzhou 215123China Key Laboratory of Materials Physics of Ministry of Education School of Physics and MicroelectronicsZhengzhou UniversityZhengzhou 450052China

Owing to enhanced charge transport efficiency arising from the ultrathin nature,two-dimensional(2D)organic semiconductor single crystals(OSSCs)are emerging as a fascinating platform for high-performance organic field-effect transistors(OFETs).However,ucoffee-ring"effect induced by an evaporation-induced convective flow near the contact line hinders the large-area growth of 2D OSSCs through a solution ***,we develop a new strategy of suppressing the"coffee-ring"effect by using an organic semiconductor:polymer blend *** the high-viscosity polymer in the organic solution,the evaporation-induced flow is remarkably weakened,ensuring the uniform molecule spreading for the 2D growth of the *** an example,wafer-scale growth of crystalline film consisting of few-layered 2,7-didecylbenzothienobenzothiophene(C10-BTBT)crystals was successfully accomplished via blade *** based on the crystalline film exhibited a maximum hole mobility up to 12.6 cm^2·V^-1·s^-1,along with an average hole mobility as high as 8.2 cm^2·V^-1·s^-*** work provides a promising strategy for the large-area growth of 2D OSSCs toward high-performance organic electronics.

关键词： two-dimensional(2D)organic semiconductor single crystals two-dimensional(2D)growth mode coffee-ring effect organic field-effect transistors

Combination of multi-focus Raman spectroscopy and compressive sensing for parallel monitoring of single-cell dynamics

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Innovative Optical Health Sciences 2021年第6期4卷 119-130页

作者： Zhenzhen Li xiujuan zhang Chengui Xiao Da Chen Shushi Huang Pengfei zhang Guiwen Wang School of Precision Instruments and Optoelectronics Engineering Tianjin University Tianjin 300072China Guangxi Key Laboratory of Marine Natural Products and Combinatorial Biosynthesis Chemistry Guangxi Academy of Sciences 98 Daling Road NanningGuangxi 530007China College of Physics Science and Technology Guangxi Normal University 15 Yucai Road GuilinGuangxi 541004China Food Inspection and Quarantine Technology Center of Shenzhen Customs Shenzhen Academy of Inspection and Quarantine Shenzhen Guangdong 518045China Center for Aircraft Fire and Emergency Civil Aviation University of China Tianjin 300300China

To overcome the low efficiency of conventional confocal Raman spectroscopy,many efforts have been devoted to parallelizing the Raman excitation and acquisition,in which the scattering from multiple foci is projected onto different locations on a spectrometer's CCD,along either its vertical,horizontal dimension,or even *** the latter projection scheme relieves the limitation on the row numbers of the CCD,the spectra of multiple foci are recorded in one spectral channel,resulting in spectral ***,we developed a method under a com-pressive sensing framework to demultiplex the superimposed spectra of multiple cells during their dynamic *** the previous methods which ignore the information connection be-tween the spectra of the cells recorded at different time,the proposed method utilizes a prior that a cell's spectra acquired at different time have the same sparsity structure in their principal *** than independently demultiplexing the mixed spectra at the individual time intervals,the method demultiplexes the whole spectral sequence acquired continuously during the dynamic *** penalizing the sparsity combined from all time intervals,the collaborative optimization of the inversion problem gave more accurate recovery *** performances of the method were substantiated by a 1D Raman tweezers array,which monitored the germination of multiple bacterial *** method can be extended to the monitoring of many living cells randomly scattering on a coverslip,and has a potential to improve the throughput by a few orders.

关键词： Confocal Raman spectroscopy compressive sensing single-cell dynamics