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Biodegradable Zn-Sr alloy for bone regeneration in rat femoral condyle defect model: In vitro and in vivo studies

Bioactive Materials 2021年第6期6卷 1588-1604页

作者： Bo jia Hongtao Yang Zechuan Zhang Xinhua Qu xiufeng jia Qiang Wu Yu Han Yufeng Zheng Kerong Dai Department of Orthopaedic Surgery Shanghai Key Laboratory of Orthopaedic ImplantsShanghai Ninth People’s HospitalShanghai Jiaotong UniversitySchool of MedicineShanghai200011China Department of Materials Science and Engineering College of EngineeringPeking UniversityBeijing100871China Department of Orthopedics Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Materials Science and Engineering The Ohio State UniversityColumbusOH43210United States Department of Bone and Joint Surgery Renji HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghai200127China Department of Orthopaedic Surgery Wudi People’s HospitalBinzhou251900China

Bone defects are commonly caused by severe trauma,malignant tumors,or congenital diseases and remain among the toughest clinical problems faced by orthopedic surgeons,especially when of critical *** zinc-based metals have recently gained popularity for their desirable biocompatibility,suitable degradation rate,and favorable osteogenesis-promoting *** biphasic activity of Sr promotes osteogenesis and inhibits osteoclastogenesis,which imparts Zn-Sr alloys with the ideal theoretical osteogenic ***,a biodegradable Zn-Sr binary alloy system was *** cytocompatibility and osteogenesis of the Zn-Sr alloys were significantly better than those of pure Zn in MC3T3-E1 ***-sequencing illustrated that the Zn-0.8Sr alloy promoted osteogenesis by activating the wnt/β-catenin,PI3K/Akt,and MAPK/Erk signaling ***,rat femoral condyle defects were repaired using Zn-0.8Sr alloy scaffolds,with pure Ti as a *** scaffold-bone integration and bone ingrowth confirmed the favorable in vivo repair properties of the Zn-Sr alloy,which was verified to offer satisfactory biosafety based on the hematoxylin-eosin(H&E)staining and ion concentration testing of important *** Zn-0.8Sr alloy was identified as an ideal bone repair material candidate,especially for application in critical-sized defects on load-bearing sites due to its favorable biocompatibility and osteogenic properties in vitro and in vivo.

关键词： Biodegradable metal Zn–Sr alloy Bone defects Bone repair material Osteogenesis

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低碱度烧结矿性能研究及应用实践

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烧结球团 2017年第5期42卷 12-17,28页

作者：贾秀凤宁波钢铁有限公司炼铁厂浙江宁波315807

在市场块矿溢价不断变化的情况下,尤其是在宁波钢铁有限公司烧结产能严重过剩、烧结矿的性价比优于块矿的前提下,提高烧结矿入炉比例可以大大提高企业成本竞争力。而绝大多数的钢铁企业烧结矿碱度都控制在1.78以上,低碱度烧结矿生产经... 详细信息

在市场块矿溢价不断变化的情况下,尤其是在宁波钢铁有限公司烧结产能严重过剩、烧结矿的性价比优于块矿的前提下,提高烧结矿入炉比例可以大大提高企业成本竞争力。而绝大多数的钢铁企业烧结矿碱度都控制在1.78以上,低碱度烧结矿生产经验和技术研究相对缺乏,因此,此项目研究为行业和企业提供了可贵经验,为低碱度烧结矿的技术发展打下了坚实的基础。

关键词：低碱度烧结矿试验研究应用

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Quantitative &Qualitative Regulation of Peripheral Leukocyte Subsets plus Emotional Hormones by Floor Heating

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Open Journal of Rheumatology and Autoimmune Diseases 2014年第2期4卷 97-105页

作者： Nobuo Yamaguchi Amat Nurmuhammad Jameas Zhao xiufeng jia jiao jian Rui Chen Tsugiya Murayama Deaprtment of Microbiology and Immunology Faculty of Pharmaceutical Sciences Hokuriku University Kanazawa Japan Ishikawa Natural Medicinal Products Research Center Kanazawa Japan Uighur Medicine Department of Xinjiang Medical University Urumqi City China Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China

A floor heating system is a traditionary famous in Asian countries, especially in North East of China and Korea. In this report, we intended to clarify the effect of floor hating system for accessing a peripheral leukocyte regulation in winter season by evidence-based manner more than VAS. We set up two different office rooms heat-controlled by floor heating and air-conditioned by ceiling electric heater. Both qualitative and quantitative approaches determine which are better therapeutic effective recipes for this trial. The elements were evaluated by the total number of peripheral leukocyte, granulocyte and lymphocyte ratio and lymphocyte subsets. For 5 days of working in each conditioned room, the volunteers were changed the room after one-week interval for cooling down. Floor heating system regulated total number of peripheral leukocyte. The mode of the action for the high number of the volunteer was down-regulated. On the contrary, in lower numbers it was up-regulated after the trial. The number of leukocyte subsets, granulocyte and lymphocyte were also regulated by dose dependent manner. Emotional hormone, adrenalin, cortisone and nor-adrenaline were down regulated by floor heating but dopamine was up-regulated by this heating system. The reversal results were obtained by the group who worked in the conditioned room by the system heating from ceiling.

关键词： Room Temp Control Floor Heating Leukocyte Subsets Ratio Emotional Hormone

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NaHCO_(3)+Na_(2)CO_(3)复合盐碱胁迫对苜蓿幼苗生理代谢的影响

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黑龙江畜牧兽医 2021年第23期 99-103页

作者：贾秀峰李波齐齐哈尔大学教师教育学院黑龙江齐齐哈尔161006 齐齐哈尔大学生命科学与农林学院抗性基因工程与寒地生物多样性保护黑龙江省重点实验室黑龙江齐齐哈尔161006

为了探讨NaHCO_(3)+Na_(2)CO_(3)复合盐碱胁迫对苜蓿(Medicago sativa L.)幼苗叶片生理的影响,试验对龙牧807苜蓿幼苗进行50,100,150,200,250 mmol/L NaHCO_(3)+Na_(2)CO_(3)(9∶1)复合盐碱胁迫,分析复合盐碱胁迫下对苜蓿叶片的渗透调节物质(可溶性糖、脯氨酸、可溶性蛋白)、膜质透性(相对电导率、丙二醛)、抗氧化酶活性(过氧化物酶、超氧化物歧化酶、过氧化氢酶)和代谢物质(硝态氮、还原型谷胱甘肽、乙醇酸氧化酶)的影响,对各指标进行相关性分析,并利用隶属函数法综合评价最佳NaHCO_(3)+Na_(2)CO_(3)复合盐碱胁迫浓度。结果表明:随着NaHCO_(3)+Na_(2)CO_(3)复合盐碱浓度增加,幼苗叶片中可溶性糖、可溶性蛋白、脯氨酸含量和过氧化物酶、超氧化物歧化酶活性在150 mmol/L NaHCO_(3)+Na_(2)CO_(3)复合盐碱浓度达最大值,过氧化氢酶活性和丙二醛含量、相对电导率、还原型谷胱甘肽含量呈上升趋势,乙醇酸氧化酶活性和硝态氮含量均呈下降趋势。在苜蓿抗复合盐碱的11项指标相关性分析中,丙二醛与相对电导率、过氧化氢酶,相对电导率、还原型谷胱甘肽与过氧化氢酶,硝态氮与乙醇酸氧化酶之间呈极显著正相关(P<0.01)。11项指标隶属函数分析显示龙牧807苜蓿苗期最适NaHCO_(3)+Na_(2)CO_(3)复合浓度为150 mmol/L。说明紫花苜蓿对NaHCO_(3)+Na_(2)CO_(3)复合盐碱有较强的抗性,可恢复盐碱草地退化。

关键词：苜蓿 NaHCO_(3)+Na_(2)CO_(3)复合盐碱胁迫生理代谢隶属函数分析相关性分析

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Quantitative regulation of peripheral leukocyte by light exercise and tailored scale for assessment

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Open Journal of Immunology 2013年第4期3卷 175-183页

作者： Nobuo Yamaguchi Rui Chen Kazuhiro Okamoto Takafumi Takei Misao Tsubokawa Daisuke Sakamoto xiufeng jia Wenhan Wan Tsugiya Murayama Deaprtment of Microbiology and Immunology Faculty of Pharmaceutical Sciences Hokuriku University Kanazawa Japan Department of Heart Surgery Kanazawa Medical University Himi Municipal Hospital Himi City Japan Department of Rehabilitation Kanazawa Medical University Uchinada-machi Japan Ishikawa Medicinal Products Research Center Kanazawa Japan Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China

Two primary defense systems develop in vertebrates, innate and adaptive. However, every individual exposes to the risk of immunodeficiency in daily life with both internal and external stimuli. In this report, we tried to report two different stimuli for regulating the immune system modulate and discussed how we can compare and select each menu by evidence-based manner more than VAS. In a series of investigation, we have assessed the various leukocyte regulating menus such as hot spring hydrotherapy, acupuncture & moxibution, light walking, independent of the western medicine. In this report, we try to compare the regulatory effect of light exercise under the influence of hypothalamus system. Their effects of elements were evaluated by the total number of peripheral leukocyte, its subsets, granulocyte and lymphocyte ratio. The regulative effects were confirmed also by other menu such as hydrotherapy, acupuncture, walking etc. However, by simply comparing the group before with the group after CAM, we cannot catch the real regulatory effect by each menu. So we tried to show the effect by trying to indicate the constitution/condition dependent manner. The effect was not uniform to each individual but it was dependent on each condition/constitution before the start of the exercise. This was one of the main purposes of this report for summarizing that it is important to regulate the number and levels of each factor as ideal value. In other words, the regulation of each factor affected under the hypothalamus system is regulated with each constitution, under the influence of daily circumstances. The mode of regulation was the same in each menu, indicating the higher level was down regular and lower level was up regular. Moreover, each vector of change was reversely correlated to the value of the day before. The other purpose of this study was designed to establish the regulatory effect of this light exercise which is not limited in the number of leukocyte in peripheral. Li

关键词： Light Exercise Walking Peripheral Leukocyte Leukocyte Subsets Ratio Metabolic Rate

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新型电力系统下多元资源发电容量充裕性评估与保障机制

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电力系统自动化 2024年第11期48卷 77-87页

作者：黄海涛贾秀锋程凯许佳丹上海电力大学电气工程学院上海市200090 国家电网公司华东分部上海市200120 国网浙江省电力有限公司温岭市供电公司浙江省温岭市317500

为了适应新型电力系统下容量资源多元化新趋势与投资激励新要求,针对中国发电容量充裕性保障机制建设问题,构建了考虑源储荷多元资源的容量补贴价格机制与容量评估方法。首先,基于边际发电成本理论,揭示了纯电能量市场“缺钱问题”与容... 详细信息

为了适应新型电力系统下容量资源多元化新趋势与投资激励新要求,针对中国发电容量充裕性保障机制建设问题,构建了考虑源储荷多元资源的容量补贴价格机制与容量评估方法。首先,基于边际发电成本理论,揭示了纯电能量市场“缺钱问题”与容量定价原理,提出容量补贴价格制定方法,引入容量调整系数有效激励投资。然后,紧密结合源储荷资源为系统峰荷容量提供支撑的不同特征,建立风光水可再生电源和新型储荷主体有功出力与调度模型,与两态法融合构建各类元件模型,采用序贯蒙特卡洛模拟建立了多元化资源充裕容量的可靠性评估方法。在此基础上,提出分类差别实用化评估方法,克服风光储荷传统评估方法的缺陷,较为科学地反映各类资源对容量支撑的实际贡献,兼顾计算简单透明。最后,算例验证表明,该机制能够实现公平补偿,提供科学的发电投资信号并确保回收,保障发电容量充裕与电价稳定,并且实用化评估方法较好平衡了评估精度与政策实施间的关系。

关键词：新型电力系统发电容量充裕性保障机制容量补贴电价评估源储荷

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宁钢烧结烟气循环系统的节能减排效果

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烧结球团 2015年第4期40卷 51-54页

作者：贾秀凤喻波宁波钢铁有限公司炼铁厂浙江宁波315807

宁钢烧结烟气循环系统是中国大陆第一套投入工业化应用的烟气循环利用系统,借鉴国外烟气循环系统的经验,结合宁钢自身的工艺布局特点,形成了具有自身特色的烟气循环工艺。为验证该系统满负荷生产下的节能减排效果,宁波钢铁邀请第三方检... 详细信息

宁钢烧结烟气循环系统是中国大陆第一套投入工业化应用的烟气循环利用系统,借鉴国外烟气循环系统的经验,结合宁钢自身的工艺布局特点,形成了具有自身特色的烟气循环工艺。为验证该系统满负荷生产下的节能减排效果,宁波钢铁邀请第三方检测评估单位,对该系统进行了试验。结果表明,满负荷生产时,该系统在降低能耗、减少污染物排放方面都有明显的效果。

关键词：烟气循环烧结固体燃耗污染排放总量

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Hot Spring Hydro Therapy Regulates Peripheral Leukocyte Together with Emotional Hormone and Receptor Positive Lymphocytes According to Each Constitution/Condition

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Open Journal of Rheumatology and Autoimmune Diseases 2013年第3期3卷 140-153页

作者： Yoshihiko Kitada Kazuhiro Okamoto Takafumi Takei xiufeng jia Rui Chen Nobuo Yamaguchi Misao Tsubokawa Wen Hsin Wu Tsugiya Murayama Kenji Kawakita Deaprtment of Microbiology and Immunology Faculty of Pharmaceutical Sciences Hokuriku University Kanazawa Japan Deaprtment of Physiology Meiji University of Integrative Medicine Kyoto Japan. Department of Rehabilitation Kanazawa Medical University Uchinada-machi Japan Ishikawa Medicinal Products Research Center Kanazawa Japan Medical School College of Medicine Taipei Medical University Taiwan Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan China

Two primary defense systems develop in vertebrates, innate and adaptive. Despite those defense systems, the overwhelming problems of possessing this dual system, the innate or adoptive do not seem to guard or even prevent the development of one internal threat to survival, moreover sometimes direct to autoimmunity accompanying hypersensitivity. Further, every individual exposes to the risk of immunodeficiency in daily life with both internal and external stimuli. In this report, we tried to report the suitable menu for regulating the immune system modulate and discuss how we can compare and select each menu by evidence-based manner more than VAS. In a series of investigation, we have assessed the various health promoting menus such as hot spring hydrotherapy, acupuncture & moxibustion, light walking, independent to the western medicine. In this report, we try to summarize the regulatory effect of hot spring hydrotherapy as our representative menu under the influence of hypothalamus system. Their effects of elements were evaluated by the total number of peripheral leukocyte, its subsets, granulocyte and lymphocyte ratio, emotional hormones, receptor positive lymphoid cells. The regulative effects were confirmed also by other menu than hydrotherapy, acupuncture, walking etc. However, just by the simple comparison between the group before and after the hydrotherapy, we cannot exhibit the real regulatory effect by each menu. So we tried to show the effect by trying to indicate the constitution/condition dependent manner. Because the effect was not uniformly to each individual but it was dependent on each condition/constitution before the start of the menu. This is the one of the main proposes of this report for summaries that it is important to regulate the number and levels of each factor as ideal value. In other words, the regulation of each factor affected under the hypothalamus system is regulated with each constitution, under the influence of daily circumstances. T

关键词： Hot Spring Hydrotherapy Peripheral Leukocyte Leukocyte Subsets Ratio Adrenaline Dopamine β2-Adrenergic Receptor Flow-Cytometry Constitution CAM Therapeutic Menu

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Development and commercial application of Baosteel sintering flue gas recirculating process

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Baosteel Technical Research 2014年第4期8卷 1-8页

作者： CUI jian LI Xianwei SHI Lei DU Hongjin jia xiufeng XI Saifeng YU Bo WANG Ruyi YU Yongmei JIN Chun YANG Yun Baosteel Group Corporation Research Institute Baoshan Iron & Steel Co.Ltd. Baosteel Stainless Steel Co. Ltd. Ningbo Iron & Steel Co. Ltd. Baosteel Engineering & Technology Group Co. Ltd.

Because of the low temperature, large waste gas volume, high pollutant content, and complicated compositions, waste heat recovery and emission gas treatment of sintering flue gas have always presented a challenge in the steel industry, and this issue has attracted widespread attention both locally and abroad. Recently, based on the first domestic pilot plant and demonstration project, Baosteel has performed a series of innovative research and development investigations on its sintering flue gas recirculating （SFGR） process,in which the system design and optimization, dioxin-related contaminant source suppression, ore matching structure optimization, wear- resistant design of cycling fans and pipelines, high-efficiency dust removal equipment, system control and stable operation strategy, flue gas mixing and switching control, circular hood sealing, oxygen content conditioning, recirculation sintering system process control, and model development have been studied, and a complete set of equipment and technology for the SFGR process has been initially developed. The investigation results suggest that the SFGR process can not only significantly reduce exhaust gas volume and pollutant emissions but also recover low-temperature waste heat and reduce the energy consumption of sintering; therefore, the overall technologies possess great value in energy savings ,pollution emission reduction, and sintering ore quality/yield improvement.

关键词： SFGR process sintering waste gas recirculation pilot plant demonstration project engineering application

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大学英语汉译英教学新探——基于大学英语四级考试汉译英题型调整后的思考

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广西科技师范学院学报 2018年第4期33卷 104-107页

作者：贾秀峰苏州科技大学外国语学院江苏苏州215009

大学英语四级考试汉译英测试题型由测试语言技能的句子翻译改为测试文化传播能力的段落翻译,这一调整势必对大学英语汉译英教学的内容和模式产生重要的影响。大学英语汉译英教学引入中华文化的段落翻译有助于培养大学英语学习者的英语... 详细信息

大学英语四级考试汉译英测试题型由测试语言技能的句子翻译改为测试文化传播能力的段落翻译,这一调整势必对大学英语汉译英教学的内容和模式产生重要的影响。大学英语汉译英教学引入中华文化的段落翻译有助于培养大学英语学习者的英语应用能力和在语境中传递中华文化信息的能力。

关键词：大学英语段落翻译文化传播

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