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Effect of somatostatin analogue octreotide injected into the third cerebral ventricle on pentagastrin-induced gastric acid secretion in rats

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World Journal of Gastroenterology 2006年第17期12卷 2767-2769页

作者： feng Gao xiu-fen Hu Department of Endocrinology Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China Tongji Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 Hubei Province China

AIM： To investigate the effect of long-lasting somatostatin analogue octreotide （Oct） injected into the third cerebral ventricle （TCV） on gastric acid secretion in rats. METHODS： TCVs were cannulated in male Wistar rats anesthetized with sodium pentobarbital. One week later acute gastric lumen perfusion was carried out and gastric acid was continuously washed with 37℃ saline by a perfusion pump. Gastric perfusion samples were collected every 10 min and titrated by 0.01 moL/L NaOH to neutral. On the basis of subcutaneous （sc） injection of pentagastrin （G-5, 160 μg/kg）, Oct （0.025 μg, 0.05 μg, 0.1 μg, n=12 in each group） or vehicle （pyrogen-free physiological saline, n = 10） was injected into the TCV, Before and after the TCV injection, 1 h total acid output （TAO） was determined and experimental data were expressed in change rate （%） of TAO. RESULTS： Oct （0.025, 0.05 and 0.1 μg） injected into the TCV resulted in change rate of 1.56% （P〉0.05）, 20.21% （P〈 0.01） and 37.82% of TAO （P〈 0.001）, respectively. Moreover, comparison in change rate of TAO among these 3 doses showed P〈 0.05 between 0.025μg and 0.05 μg, P〈 0.01 between 0.025 μg and ***, and P〈 0.05 between 0.05μg and 0.1 μg. However, sc injection of 0.05 μg Oct had no effect on G-5 stimulated gastric acid secretion. CONCLUSION： Octreotide injected into the third cerebral ventricle inhibits gastrin-induced gastric acid secretion in a dose-dependent manner.

关键词： Octreotide Somatostatin analogue Third cerebal ventricle Gastric acid Gastrin

Reversible posterior leukoencephalopathy syndrome induced by bevacizumab plus chemotherapy in colorectal cancer

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World Journal of Gastroenterology 2014年第21期20卷 6691-6697页

作者： Wei Wang li-Rong Zhao xiu-Qiang lin fen feng Department of Gastroenterology Foshan First People’s Hospital

Reversible posterior leukoencephalopathy syndrome(RPLS)is a rare brain-capillary leak syndrome,characterized by clinical symptoms of headache,visual loss,seizures and altered mental *** syndrome is usually reversible and is associated with hypertension,nephropathy,and use of immunosuppressive medication and cytotoxic *** describe two rare cases of RPLS occurring in colorectal cancer,both of which presented with coma,that we believe can be directly attributed to bevacizumab,a monoclonal antibody that inhibits the angiogenesis of tumours by specifically blocking vascular endothelial growth *** analysed the clinical features,risk factors and outcomes of RPLS in these two patients,and although no typical finding was identified on imaging examination,we found that inadequate blood pressure control was one of the risk factors leading to RPLS and that supportive treatment including intensive blood pressure control improved *** to the increasing use of bevacizumab in colorectal cancer,clinicians should be aware of this potential complication.

关键词： Bevacizumab Reversible posterior leukoencephalopathy syndrome Colorectal cancer Hypertension Coma

Effect of bifidobacterium on defensin-5 expression in intestinal injury of preweaning rats

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World Journal of Gastroenterology 2015年第9期21卷 2638-2644页

作者： Wei Wang Shu-fen Yang li-Hong Ren xiu-xiu Zhang Shui-lian Yu Department of Pediatrics the Second Affiliated Hospital of Harbin Medical University

AIM:To investigate the protective effect of bifidobacterium in endotoxin-induced intestinal injury in preweaning ***:Preweaning rats were randomly divided into three groups(n =40 for each):a control group(groupC),a model group(group E) and a treatment group(group T).Both groups E and T were intraperitoneally injected with lipopolysaccharide(LPS) at a dose of 5 mg/kg(5 mg/L in normal saline),and group T was intragastrically administrated with bifidobacterium suspension(2.0 × 109 CFU/m L,0.5 m L each time,twice a day,until the end of the experiment) 7 d before LPS *** C was intraperitoneally injected with normal *** intraperitoneal injection and intragastric administration,the rats were placed back to the initial cage to receive breast *** rats were killed at 2,6,12,24 or 72 h,respectively,after endotoxin or physiological saline injection to collect serum and ileal tissue ***(MPO) contents in serum and ileum were detected at different times,and expression of ileal defensin-5 m RNA was evaluated by reverse transcription-polymerase chain ***:Serum and ileal MPO contents in group E were significantly higher than those in group C(serum contents:107.50 ± 17.70 vs 157.14 ± 24.67,P fensin-5 m RNA in group E was significantly higher than that in group C(0.953 ± 0.238 vs 0.631 ± 0.146,P fensin-5 m RNA in group T was significantly lower than that in group E(0.487 ± 0.149 vs 0.758 ± 0.160,P fensin-5 m RNA at 2 h in group T was significantly higher than that in group C(0.824 ± 0.158 vs

关键词： Bifidobacterium lipopolysaccharide Ileum Myelopero

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对石家庄市青少年体质与健康状况的调查研究

石家庄师范专科学校学报 2003年第3期5卷 54-56,64页

作者：李秀芬李伟刘洪英石家庄师范专科学校体育系河北石家庄050801 石家庄市23中河北石家庄050011

对石家庄市大中小学生体质与健康状况的调查分析 ,得到学生体质与健康状况不够理想的结论。改进对策 :依法治教、更新教育观念、提高师资队伍整体水平 ;在完成教学计划情况下 ,把学生感兴趣 ,具有特长的项目恰当地安排于教学中。

关键词：石家庄市青少年体质健康状况调查研究依法治教教育观念师资队伍教学方法体育活动

Effects of nitrogen management on the ratoon crop yield and head rice yield in South USA

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Journal of Integrative Agriculture 2021年第6期20卷 1457-1464页

作者： WANG Yue-chao li xiu-fen Lee TARPLEY PENG Shao-bing DOU Fu-gen Texas A&M Agrilife Research Center 1509 Aggie DriveBeaumontTX 77713USA National Key Laboratory of Crop Genetic Improvement/Key Laboratory of Crop Ecophysiology and Farming System in the Middle Reaches of the Yangtze River Ministry of Agriculture and Rural Affairs/College of Plant Science and TechnologyHuazhong Agricultural UniversityWuhan 430070P.R.China

Ratoon rice cropping is an important component of the rice cropping system in Texas and south Louisiana,USA,and expanded to Asian countries in *** field studies were conducted with widely planted rice(Oryza sativa L.)cultivars at Eagle Lake,Texas,USA to determine the effects of nitrogen(N)management in main(first)crop(MC)and ratoon(second)crop(RC)on RC *** 2012 and 2013,one cultivar(Presidio)was adopted to determine the effects of RC N management on ratoon yield and head rice *** 2016 and 2017,CL153,CL163 and CL272 in addition to Presidio were adopted to examine the effect of MC N management on ratoon yield and head rice yield.N applied at preflood after MC harvest considerably improved RC *** of 99 kg N ha^(–1)at preflood after MC harvest was practically adequate for RC regrowth,development and approaching the yield potential for *** could produce quite high average grain yields of 5.90 to 6.53 t ha–1 in 2012 and 2013,*** crop N rate only significantly affected MC yield;however,given N applied of 99 kg ha^(–1)at preflood after MC harvest,ratoon yield was not significantly affected by MC N *** the main nor ratoon crop N management had a significant effect on RC head rice *** RC head rice yields(55–65%)were observed in all of the four cultivars and 4 years except for CL272 in *** results indicat that without very high N fertilizer application,rice ratoon crop could produce a considerable grain yield and an expectative head rice *** ratooning could be a practical way to increase rice yields with the minimal input in south Texas and regions with a similar climate.

关键词： rice nitrogen management main crop ratoon crop grain yield head rice yield

降纤药物治疗脑梗塞发生静脉穿刺部位皮下出血的原因及对策

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新乡医学院学报 2005年第2期22卷 160-161页

作者：顾建秀于本芬李文霞沈桂林新乡市第二人民医院河南新乡453002

目的　　探讨降纤药治疗脑梗塞(CI)患者引起静脉穿刺部位皮下出血原因及预防。方法　对34例因降纤药静脉注射致皮下出血的CI患者进行观察分析。结果　正确的拔针方法、避免拔针后换手按压及延长按压时间可预防穿刺部位皮下出血。结论　... 详细信息

目的　　探讨降纤药治疗脑梗塞(CI)患者引起静脉穿刺部位皮下出血原因及预防。方法　对34例因降纤药静脉注射致皮下出血的CI患者进行观察分析。结果　正确的拔针方法、避免拔针后换手按压及延长按压时间可预防穿刺部位皮下出血。结论　上述综合方法是减少降纤药静脉注射致皮下出血的有效措施。

关键词：脑梗塞降纤治疗皮下出血

血清VEGF-C、VEGFR-2、3表达水平在急性白血病疗效监测及预后判断中的应用

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昆明医科大学学报 2016年第11期37卷 60-63页

作者：沈秀芬薛丽番寿蕊何晓娟王雪娇余景星夏梅花尹列芬昆明医科大学第二附属医院检验科云南昆明650101 昆明医科大学第二附属医院血液科云南昆明650101

目的观察AL患者血清中VEGF-C及VEGFR-2、VEGFR-3表达水平,探讨其临床意义.方法采用酶联免疫吸附法对51例确诊为AL患者、接受治疗观察的43例及16例健康献血者血清中VEGF-C、VEGFR-2、3进行检测.结果 (1)AL患者VEGF-C、VEGFR-2及VEGFR-3水... 详细信息

目的观察AL患者血清中VEGF-C及VEGFR-2、VEGFR-3表达水平,探讨其临床意义.方法采用酶联免疫吸附法对51例确诊为AL患者、接受治疗观察的43例及16例健康献血者血清中VEGF-C、VEGFR-2、3进行检测.结果 (1)AL患者VEGF-C、VEGFR-2及VEGFR-3水平,较正常对照组高,差异有统计学意义(P0.05);(3)治疗后CR组和NR组VEGFR-3水平较治疗前无明显变化(P>0.05);(4)治疗前NR组VEGFR-2、VEGFR-3水平明显高于CR组,具有统计学意义(P<0.01).结论观察AL患者治疗前后VEGF-C及VEGFR-2、3表达水平,对预后判断、疗效评估和病情监测具有重要临床意义.

关键词：急性白血病血管内皮生长因子血管内皮生长因子受体酶联免疫吸附法

Climate Change Impact and Its Contribution Share to Paddy Rice Production in Jiangxi, China

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Journal of Integrative Agriculture 2014年第7期13卷 1565-1574页

作者： li Wen-juan TANG Hua-jun QIN Zhi-hao YOU Fei WANG xiu-fen CHEN Chang-li JI Jian-hua liU xiu-mei Institute of Agricultural Resources and Regional Planning Chinese Academy of Agricultural Sciences Key Laboratory of Agri-Informatics Ministry of Agriculture/Chinese Academy of Agricultural Sciences International Institute for Earth System Science Nanjing University Institute of Crop Sciences Chinese Academy of Agricultural Sciences Institute of Soil Fertilizer and Resource Environment Jiangxi Academy of Agricultural Sciences

In the study, an improved approach was proposed to identify the contribution shares of three group factors that are climate, technology and input, social economic factors by which the grain production is shaped. In order to calibrate the method, Jiangxi Province, one of the main paddy rice producers in China was taken as an example. Based on 50 years （1961-2010） meteorological and statistic data, using GIS and statistical analysis tools, the three group factors that in certain extent impact China＇s paddy rice production have been analyzed quantitatively. The individual and interactive contribution shares of each factor group have been identiifed via eta square （η2）. In the paper, two group ordinary leasr square （OLS） models, paddy models and climate models, have been constructed for further analysis. Each model group consists of seven models, one full model and six partial models. The results of paddy models show that climate factors individually and interactively contribute 11.42-15.25%explanatory power to the variation of paddy rice production in the studied province. Technology and input factors contribute 16.17%individually and another 8.46%interactively together with climate factors, totally contributing about 25%. Social economic factors contribute about 7%of which 4.65%is individual contribution and 2.49%is interactive contribution together with climate factors. The three factor groups individually contribute about 23%and interactively contribute additional 41%to paddy rice production. In addition every two of the three factor groups also function interactively and contribute about 22%. Among the three factor groups, technology and input are the most important factors to paddy rice production. The results of climate models support the results of paddy models, and display that solar radiation （indicated by sunshine hour variable） is the dominate climate factor for paddy rice production.

关键词： climate change food security paddy rice production contribution share China

liquid-Solid Phase Transition in Sodium Dodecyl Sulfate Aqueous Solutions by Acoustic Nonlinearity Parameter B/A

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Chinese Physics Letters 1996年第5期13卷 366-369页

作者： LU Zhi-qu GONG xiu-fen liU Jie-hui State Key Laboratory of Modern Acoustics Institute of AcousticsNanjing UniversityNanjing 210093

The paper reports the study of liquid-solid phase transition in sodium dodecyl sulfate(SDS)aqueous solution by using acoustic nonlinearity parameter B/*** was found that the point of inflexion occurred in the B/A-T curve just at the liquid-solid phase transition point of SDS aqueous *** result indicates that the nonlinearity parameter B/A can perfectly display the *** phase transition of SDS solution and may develop a new B/A method for determining the phase transition point of fluid.

关键词： solution. nonlinearity transition