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World Journal of Gastrointestinal Oncology 2024年第1期16卷 214-233页

作者： Mao-xiu Yuan Qi-Gui Cai Zhen-yang Zhang Jian-Zhong Zhou Cai-Yun Lan Jiang-bo Lin The Graduate School Fujian Medical UniversityFuzhou 350000Fujian ProvinceChina Department of Thoracic Surgery Affiliated Hospital of Jinggangshan UniversityJi’an 343000Jiangxi ProvinceChina Department of Thoracic Surgery Fujian Medical University Union HospitalFuzhou 350000Fujian ProvinceChina

BACKGROUND The effectiveness of neoadjuvant therapy in esophageal cancer(EC)treatment is still a subject of *** To compare the clinical efficacy and toxic side effects between neoadjuvant chemoradiotherapy(nCRT)and neoadjuvant chemotherapy(nCT)for locally advanced EC(LAEC).METHODS A comprehensive search was conducted using multiple databases,including PubMed,EMBASE,MEDLINE,Science Direct,The Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,Chinese Science and Technology Journal Database,and Chinese Biomedical Literature Database *** up to December 2022 comparing nCRT and nCT in patients with EC were *** The analysis revealed significant differences between nCRT and nCT in terms of disease-free *** results indicated that nCRT provided better outcomes in terms of the 3-year overall survival rate(OSR)[odds ratio(OR)=0.95],complete response rate(OR=3.15),and R0 clearance rate(CR)(OR=2.25).However,nCT demonstrated a better 5-year OSR(OR=1.02)than ***,when compared to nCRT,nCT showed reduced risks of cardiac complications(OR=1.15)and pulmonary complications(OR=1.30).CONCLUSION Overall,both nCRT and nCT were effective in terms of survival outcomes for ***,nCT exhibited better performance in terms of postoperative complications.

关键词： Esophageal cancer Neoadjuvant chemoradiotherapy Radical resection for esophageal cancer Neoadjuvant chemotherapy Meta-analysis

A Novel Ternary Composite of Polyurethane/Polyaniline/Nanosilica with Antistatic Property and Excellent Mechanical Strength:Preparation and Mechanism

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Chinese Journal of Polymer Science 2022年第7期40卷 789-798页

作者： xiu-Zhi Tian Rui yang Jia-Jia Ma Yong-Hao Ni Hai-bo Deng Lei Dai Jiao-Jun Tan Mei-Yun Zhang Xue Jiang College of Bioresource Chemical and Materials Engineering Shaanxi University of Science and TechnologyXi’an710021China College of Textile Science and Engineering Jiangnan UniversityWuxi214122China Limerick Pulp&Paper Centre&Department of Chemical Engineering University of New BrunswickFrederictonNew BrunswickE3B5A3Canada

Antistatic and strength properties are of vital importance for polyurethane rubber used in moving parts of many industrial ***,polyurethane was composited with polyaniline and nanosilica based on in situ synthesis of polymer and physical mixing of these fillers to reach desired antistatic and mechanical ***,morphological and thermal properties of the polyurethane/polyaniline/nanosilica composites were *** electrical resistivity of the composite decreased from 1.1×10^(6)MΩto 7.6×10^(4)MΩas a result of the addition of 4%*** tensile strength and elongation at break of the polyurethane composites improved by nearly 300%and100%,respectively,when compared with those of the neat *** electronic resistance of PU/PANI/NS ternary is low enough for its antistatic property and decreases with the increase of the added nanosilica,which is unexpectedly and rather *** results would shed light on the development of antistatic PU with excellent mechanical performance.

关键词： Polyurethane/polyaniline/nanosilica composites Antistatic property Mechanical property Molecular simulation

Status and path of intergenerational transmission of poverty in rural China:A human capital investment perspective

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Journal of Integrative Agriculture 2021年第4期20卷 1080-1091页

作者： BAI Yun-li ZHANG Lin-xiu SUN Ming-xing XU Xiang-bo Key Laboratory of Ecosystem Network Observation and Modeling Institute of Geographic Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101P.R.China UN Environment Programme-International Ecosystem Management Partnership Beijing 100101P.R.China

This paper focused on the intergenerational transmission of poverty in rural China by estimating the intergenerational transmission of earnings and stated its mechanism from the perspective of human capital investment before children participated in the labor *** data used in this study were longitude data collected in 2000 households of 100 villages among 25 counties across five provinces in 2005,2008,2012,2016,and *** and quantitative methods were *** found a significant intergenerational transmission of earnings in rural China,especially for the pairs of father–children and parents–*** intergenerational earnings'elasticities were much less than those in urban areas,which indicated better social mobility in rural areas than that in urban *** children with parents who could earn much were more likely to be invested before they participated in the labor market,gain a high education and have more *** cases further showed that the mechanism of human capital investment in children breaking the intergenerational transmission of poverty and promoting social mobility.

关键词： poverty intergenerational transmission human capital rural China

Tuberculosis-induced aplastic crisis and atypical lymphocyte expansion in advanced myelodysplastic syndrome:A case report and review of literature

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World Journal of Clinical Cases 2023年第19期11卷 4713-4722页

作者： Xiao-Yun Sun Xiao-Dong yang Jia Xu Nuan-Nuan xiu bo Ju Xi-Chen Zhao Department of Hematology The Central Hospital of Qingdao West Coast New AreaQingdao 266555Shandong ProvinceChina

BACKGROUND Myelodysplastic syndrome(MDS)is caused by malignant proliferation and ineffective *** somatic mutations and increased apoptosis,necroptosis and pyroptosis lead to the accumulation of earlier hematopoietic progenitors and impaired productivity of mature blood *** increased percentage of myeloblasts and the presence of unfavorable somatic mutations are signs of leukemic hematopoiesis and indicators of entrance into an advanced *** marrow cellularity and myeloblasts usually increase with disease ***,aplastic crisis occasionally occurs in advanced *** SUMMARY A 72-year-old male patient was definitively diagnosed with MDS with excess blasts-1(MDS-EB-1)based on an increase in the percentages of myeloblasts and cluster of differentiation(CD)34+hematopoietic progenitors and the identification of myeloid neoplasm-associated somatic mutations in bone marrow *** patient was treated with hypomethylation therapy and was able to maintain a steady disease state for 2 *** the treatment process,the advanced MDS patient experienced an episode of progressive pancytopenia and bone marrow *** the aplastic crisis,the bone marrow was infiltrated with sparsely distributed atypical ***,the leukemic cells *** analysis revealed that the atypical lymphocytes expressed a high frequency of CD3,CD5,CD8,CD16,CD56 and CD57,suggesting the activation of autoimmune cytotoxic T-lymphocytes and natural killer(NK)/NKT cells that suppressed both normal and leukemic *** serum levels of inflammatory cytokines,including interleukin(IL)-6,interferon-gamma(IFN-γ)and tumor necrosis factor-alpha(TNF-α),confirmed the deranged type I immune *** morphological and immunological signature led to the diagnosis of severe aplastic anemia secondary to large granule lymphocyte *** tuberculosis was suspected upon radiological examinations in the s

关键词： Myelodysplastic syndrome Aplastic crisis Atypical lymphocyte Leukemic cell regression CD56+lymphocyte expansion Disseminated tuberculosis Case report

Flared inflammatory episode transforms advanced myelodysplastic syndrome into aplastic pancytopenia:A case report and literature review

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World Journal of Clinical Cases 2023年第17期11卷 4105-4116页

作者： bo Ju Nuan-Nuan xiu Jia Xu Xiao-Dong yang Xiao-Yun Sun Xi-Chen Zhao Department of Hematology The Central Hospital of Qingdao West Coast New AreaQingdao 266555Shandong ProvinceChina

BACKGROUND Myelodysplastic syndrome(MDS)is a hematological neoplasm,and an increase in myeloblasts is representative of leukemic hematopoiesis in advanced *** MDS usually exhibits deranged autoimmunity resembling that of aplastic anemia(AA),whereas advanced MDS is characterized by a phenotype of immune *** can be normo/hyperplastic or ***,bone marrow cellularity and myeloblasts increase with disease *** from advanced MDS to AA-like syndrome with leukemic cell regression has not previously been *** SUMMARY A middle-aged Chinese woman had a 4-year history of *** months prior to admission,the patient developed gradually worsening fatigue and performance *** leukocytopenia further *** was diagnosed with MDS with excess blasts-2 based on increased bone marrow cellularity and an increased percentage of myeloblasts on marrow and blood smears,an increased percentage of cluster of differentiation(CD)34+CD33+progenitors in immunotyping analysis,a normal karyotype in cytogenetic analysis,and the identification of somatic mutations in CBL,KMT2D and NF1 in molecular ***,neutropenia was the predominant hematological abnormality,with mild anemia and thrombocytosis,and the degree of fatigue was far more severe than the degree of *** the following months,the patient experienced several febrile *** antibiotic treatments were able to control the febrile episodes,but the elevated inflammatory indices *** hematological parameters dramatically fluctuated with the waxing and waning of the inflammatory *** recurrent flares of the inflammatory condition,agranulocytosis and severe anemia developed,with mild *** the patient’s hospitalization,computed tomography(CT)scans revealed the presence of extensive inflammatory lesions involving the lungs,mediastinum,pleura,gastrointestinal tract,peritoneum and urinary tract,

关键词： Myelodysplastic syndrome Aplastic anemia Inflammatory stress Leukemic cell regression Antileukemic Case report

Influence of Annealing on Properties of ZnO Films Grown via Plasma-enhanced MOCVD

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Chemical Research in Chinese Universities 2003年第4期19卷 383-385页

作者： ZHAO Bai-jun DU Guo-tong yang Hong-jun WANG Jin-zhong ZHANG Yuan-tao yang Xiao-tian LIU bo-yang MA Yan yang Tian-peng LIU Da-li LI Wan-cheng FANG xiu-jun College of Electronics and Engineering Jilin UniversityChangchun 130023P.R.China

The structural and the optical properties of ZnO films with high quality grown via plasma-enhanced metal\|organic chemical vapour deposition(MOCVD) on C-plane sapphire substrate were studied. The crystallinity and the optical properties of the films are greatly improved having been annealed in oxygen plasma atmosphere. The structure, the band gap and the binding energy of O 1s electrons, and the molar ratio of O to Zn were determined by X-ray diffraction(XRD), photoluminescence(PL) and X-ray photoelectron scan methods. For both the annealed and the as-grown films, the exciton peak features were observed at room temperature. The band-edge photoluminescence of the annealed film is much stronger than that of the as-grown film, and the exciton peak relating to the deep level at 439 nm disappears. The molar ratio of O to Zn in the annealed film is 0 91, while it is 0 78 for the as-grown film.

关键词： Plasma-enhanced MOCVD Sapphire Substrate

Glucocorticoid-induced thrombotic microangiopathy in paroxysmal nocturnal hemoglobinuria:A case report and review of literature

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World Journal of Clinical Cases 2023年第8期11卷 1799-1807页

作者： Xiao-Dong yang bo Ju Jia Xu Nuan-Nuan xiu Xiao-Yun Sun Xi-Chen Zhao Department of Hematology The Central Hospital of Qingdao West Coast New AreaQingdao 266555Shandong ProvinceChina

BACKGROUND Thrombotic microangiopathy(TMA)is a group of disorders that converge on excessive platelet aggregation in the microvasculature,leading to consumptive thrombocytopenia,microangiopathic hemolysis and ischemic end-organ *** predisposed patients,TMA can be triggered by many environmental ***(GCs)can compromise the vascular ***,GC-associated TMA has rarely been reported,which may be due to the lack of awareness of *** the high frequency of thrombocytopenia during GC treatment,particular attention should be given to this potentially fatal *** SUMMARY An elderly Chinese man had a 12-year history of aplastic anemia(AA)and a 3-year history of paroxysmal nocturnal hemoglobinuria(PNH).Three months earlier,methylprednisolone treatment was initiated at 8 mg/d and increased to 20 mg/d to alleviate complement-mediated *** GC treatment,his platelet counts and hemoglobin levels rapidly *** admission to our hospital,the dose of methylprednisolone was increased to 60 mg/d in an attempt to enhance the suppressive ***,increasing the GC dose did not alleviate hemolysis,and his cytopenia *** evaluation of the marrow smears revealed increased cellularity with an increased percentage of erythroid progenitors without evident *** of differentiation(CD)55 and CD59 expression was significantly decreased on erythrocytes and *** the following days,platelet transfusion was required due to severe *** of platelet transfusion refractoriness indicated that the exacerbated cytopenia may have been caused by the development of TMA due to GC treatment because the transfused platelet concentrates had no defects in glycosylphosphatidylinositol-anchored *** examined blood smears and found a small number of schistocytes,dacryocytes,acanthocytes and target *** of GC treatment resulted in rapidl

关键词： Aplastic anemia Paroxysmal nocturnal hemoglobinuria Glucocorticoid Methylprednisolone Thrombotic microangiopathy Platelet transfusion refractoriness Case report

Influence of Catalyst Residues on Thermo-oxidative Aging and Thermal Stability of Poly(butene-1)

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Chinese Journal of Polymer Science 2014年第5期32卷 633-639页

作者： Bao-yu Sun Lei Cui xiu-bo Jiang Bai-yu Jiang 姚薇贺爱华 Key Laboratory of Rubber-Plastics Ministry of Education/Shandong Provincial Key Laboratory of Rubber-Plastics School of Polymer Science and Engineering Qingdao University of Science and Technology

Isotactic poly（butene-1）（iPB） with spherical morphology was synthesized successfully with bulk precipitation polymerization without post-treatment of the products. The bulk precipitation polymerization process made it possible for iPB to be used as general plastic due to the acceptable decreased cost compared with the solution polymerization process. The influence of catalyst residues on the aging and thermal stability of iPB synthesized by bulk precipitation polymerization method was investigated by gel permeation chromatography, mechanical performance testing, thermogravimetric analysis and infrared spectroscopic analysis. Commercial iPB and the lab-made iPB with varied catalyst residue contents were studied. The results demonstrated that the catalyst residues played an important role in the aging process of the iPB. A possible mechanism of aging promotion by catalyst residues was proposed.

关键词： Catalyst residues Poly(butene-1) Aging Thermal stability.

Leukemic transformation during anti-tuberculosis treatment in aplastic anemia-paroxysmal nocturnal hemoglobinuria syndrome:A case report and review of literature

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World Journal of Clinical Cases 2023年第28期11卷 6908-6919页

作者： Nuan-Nuan xiu Xiao-Dong yang Jia Xu bo Ju Xiao-Yun Sun Xi-Chen Zhao Department of Hematology The Central Hospital of Qingdao West Coast New AreaQingdao 266555Shandong ProvinceChina

BACKGROUND Accumulating evidence demonstrates that autoimmune hematopoietic failure and myeloid neoplasms have an intrinsic relationship with regard to clonal hematopoiesis and disease *** approximately 10%-15%of patients with severe aplastic anemia(SAA),the disease phenotype is transformed into myeloid neoplasms following antithymocyte globulin plus cyclosporine-based immunosuppressive *** some of these patients,myeloid neoplasms appear during or shortly after immunosuppressive *** transformation in SAA patients during anti-tuberculosis treatment has not been *** SUMMARY A middle-aged Chinese female had a 6-year history of non-SAA and a 2-year history of paroxysmal nocturnal hemoglobinuria(PNH).With aggravation of systemic inflammatory symptoms,severe pancytopenia developed,and her hemoglobinuria *** findings in cytological,immunological and cytogenetic analyses of bone marrow samples met the diagnostic criteria for“SAA.”Definitive diagnosis of disseminated tuberculosis was made in the search for infectious *** improvement in hematological parameters was achieved within 1 mo of anti-tuberculosis treatment,and complete hematological remission was achieved within 4 mo of ***,the hematological response lasted for only 3 mo,and pancytopenia *** this time,cytological findings(increased bone marrow cellularity and an increased percentage of myeloblasts that accounted for 16.0%of all nucleated hematopoietic cells),immunological findings(increased percentage of cluster of differentiation 34+cells that accounted for 12.28%of all nucleated hematopoietic cells)and molecular biological findings(identification of somatic mutations in nucleophosmin-1 and casitas B-lineage lymphoma genes)revealed that“SAA”had transformed into acute myeloid leukemia with mutated *** transformation process suggested that the leukemic clones were preexistent but were suppressed in the

关键词： Aplastic anemia Paroxysmal nocturnal hemoglobinuria Acute myeloid leukemia Tuberculosis Leukemic transformation Case report

Development of the fast arcing protection for ECRH system on the HL-2A tokamak

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核聚变与等离子体物理 2007年第1期27卷 44-47页

作者： LI xiu-juan RAO Jun WANG Ming-wei WANG Xue-yun LI bo Southwestern Institute of Physics Chengdu 610225

1 Introduction A series of engineering tests and physical experiments,including ECRH[1],was carried out on the HL-2A tokamak in 2005.A fast arcing protection system[2] was developed to ensure operating of ECRH facilit... 详细信息

关键词：弧阈值响应时间托卡马克装置