检索结果-南通市图书馆

国际中文教育资源建设背景下的对外中文词典编纂研究

在线全文

学校读者我要写书评

暂无评论

陕西师范大学学报（哲学社会科学版） 2024年第3期53卷 5-15页

作者：赵学清付露陕西师范大学文学院陕西西安710119

对外中文词典是中文二语学习者自主学习的必备工具,也是国际中文教育基础资源的重要组成部分。国际中文教育资源发展要求对外中文词典应立足现有成果,以词典用户为中心,凸显词典的外向型和学习型特征。针对词典使用率低、数字化滞后的... 详细信息

对外中文词典是中文二语学习者自主学习的必备工具,也是国际中文教育基础资源的重要组成部分。国际中文教育资源发展要求对外中文词典应立足现有成果,以词典用户为中心,凸显词典的外向型和学习型特征。针对词典使用率低、数字化滞后的现实困境,我们需要吸收语言学、词典学等学科的前沿理论,借鉴其他辞书、教学资源的数字化经验,不断完善对外中文词典的编纂实践和推广工作。同时,应利用科技赋能,加快对外中文词典数字化转型的步伐;抓住“中文+职业技能”教育趋势带来的机遇,丰富词典类型,为新形势下国际中文学习者多元的资源需求提供精准服务。

关键词：国际中文教育教学资源中文学习词典中文二语学习者

Percutaneous Penetration and Dermal Exposure Risk Assessment of UV Absorbents in Sunscreens and Isolation Cosmetics

在线全文

学校读者我要写书评

暂无评论

Environment & Health 2024年第8期2卷 541-552页

作者： lu Bai Juan Li Binbin Guo Ruitong Cai Chunyan Zhao Yanli Guo Yawei Wang Guibin Jiang State Key Laboratory of Environmental Chemistry and Ecotoxicology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China School of Environment Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310000China College of Resources and Environment University of Chinese Academy of SciencesBeijing 100049China School of Pharmacy Lanzhou UniversityLanzhou 730000China China Innovation Center Shimadzu(China)Co.Beijing 100020China

Ultraviolet absorbents(UVs)make up a group of industrial chemicals that is used in various consumer products and industrial *** to their extensive production and usage,UVs have been detected in multiple environmental ***,UVs have garnered significant attention because of their probable adverse impacts on human health and the *** study examines UVs levels in sunscreens and isolation cosmetics and further assesses human exposure to UVs through the application of *** total concentrations of nine UVs in 87 sunscreen and isolation cosmetic products ranged from 75.5 to 4.25×10^(4) ng/*** them,2-(2-hydroxy-5-methyl-phenyl)benzotriazole(UV-P)and 2-hydroxy-4-(octoxy)benzophenone(UV-531)had the highest *** of the EpiSkin model indicated rapid absorption and strong dermal penetration by UV-328 following 36 h of exposure with a cumulative absorption rate of 41.8%±2.82%.Other congeners are expected to be distributed in the dermal tissue and donor ***,this study explored potential mechanisms implicating skin biochemical barriers in the metabolism and transport of *** potential of UVs to act as substrates and inhibitors of P450 enzymes was assessed,and their metabolites were *** docking simulations demonstrated that UVs can significantly interact and bind with three transport proteins in skin:MDR1,OATP2B1,and *** UVs exposure through the skin was assessed,revealing that dermal absorption levels of UV-P in sunscreen sprays(4.66×10^(3) ng/(kg bw day))and sunscreens(6.01×10^(3) ng/(kg bw day))were close to or exceeded the reference dose(RfD)and therefore require more attention.

关键词： ultraviolet absorbents sunscreen dermal exposure dermal penetration risk assessment

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于司法裁判文本的法律要素抽取方法

中国电子科学研究院学报 2024年第6期19卷 552-558,569页

作者：董玉红卢鹏陈静郭新刚陈震中国司法大数据研究院有限公司北京100041

随着全国法院信息化建设的不断发展,积累了大规模的司法裁判文书数据,如何从法律文书数据中抽取出准确的法律要素是保障法院信息化建设的重要前提。本研究主要基于盗窃罪案件法律文书数据,采用深度学习方法构建了BERT+BiLSTM+CRF融合语... 详细信息

随着全国法院信息化建设的不断发展,积累了大规模的司法裁判文书数据,如何从法律文书数据中抽取出准确的法律要素是保障法院信息化建设的重要前提。本研究主要基于盗窃罪案件法律文书数据,采用深度学习方法构建了BERT+BiLSTM+CRF融合语言模型以解决法律文书的关键要素抽取问题。利用BERT语言模型解决文本特征表示中的一词多义问题,使用BiLSTM神经网络充分学习上下文信息的特点,采用CRF机器学习方法提取全局最优标注序列,并搭建可视化界面提供案件要素提取服务。结果表明,从整体来看,通过数据增强后所构建的BERT+BiLSTM+CRF融合语言模型面向盗窃罪案件的综合评价指标F1_score值达到了90.6%;从单个要素的抽取结果来看,该模型面向盗窃罪案件的十个法律要素的综合评价指标的F1_score值均在81.8%以上;从最佳预测性能所分布的法律要素占比来看,该模型达到最优预测性能的法律要素量达到了50%,明显优于其他模型。这说明本研究所构建的BERT+BiLSTM+CRF融合语言模型可以有效解决法律文书的关键要素抽取问题,可为全国法院信息化建设提供一定的理论依据和有效技术支撑。

关键词：法律要素抽取裁判文本 BERT BiLSTM CRF

Low-dose dopamine reduces inflammatory factors of acute pancreatitis in rats

在线全文

学校读者我要写书评

暂无评论

Hepatobiliary & Pancreatic Diseases International 2007年第6期6卷 646-649页

作者： Zhang, Shun Peng, Xin-gang Liu, Chang-Chang Liu, Hong lu, Yun Qingdao Univ Affiliated Hosp Coll Med Dept Hepatobiliary Surg Qingdao 266003 Peoples R China Qingdao Univ Affiliated Hosp Coll Med Dept Emergency Gen Med Qingdao 266003 Peoples R China

BACKGROUND: Acute pancreatitis, especially acute necrotizing pancreatitis (ANP), is a serious disease with a high morbidity because of multiorgan dysfunction. Recent studies have indicated that during the pathogenesis of ANP, changes of the microcirculation play an important role in the worsening of the disease. This study based on a. model of acute pancreatitis in Wistar rats was to determine the effect of treatment with low-dose dopamine on acute pancreatitis by the dynamic measurement of serum levels of inflammatory factors IL-6 and TNF-alpha. METHODS: Fifty Wistar rats were randomly divided into two groups, and a model of ANP was set up by injecting sodium taurocholate into the pancreatic duct. Rats in the dopamine group (treatment group) were given dopamine by vein and those in the acute pancreatitis group (control group) were given normal saline. To assess the effect of low-dose doparnine (5 mu g . kg(-1) . min(-1)) on induced acute pancreatitis, the antibody sandwich ELISA method was used to measure the serum levels of IL-6 and TNF-alpha at different times before and after the induction of ANP. RESULTS: The serum levels of IL-6 and TNF-alpha in the treatment and control groups before and after ANP induction were significantly different. There was a markedly significant difference in the comparison of the two groups after ANP induction (P0.05). Postoperative pancreatic histopathologic changes in the treatment group were more marked than those in the control group. CONCluSIONS: Low-dose dopamine is effective in treating ANP by alleviating inflammatory reactions. This effect may be related to the fact that low-dose doparnine not only can increase the blood flow of the pancreatic microcirculation but also reduce its permeability.

关键词： acute pancreatitis dopamine inflammatory factor

Ventricular system-unrelated cerebellar ependymoma:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第25期12卷 5814-5820页

作者： Chao-Ge Yang Rui-Feng Xue lu-Xia Yang Xiao-Lin Jieda Wei Xiang Jie Zhou Department of Neurosurgery The Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Neonatology Children's Medical CenterThe Affiliated Hospital of Southwest Medical UniversityLuzhou 646000Sichuan ProvinceChina

BACKGROUND An ependymoma is a glial tumor that usually occurs in or near the ventricle,close to the *** rarely occurs exclusively in the brain parenchyma without being associated with the *** SUMMARY Here,we report a rare case of a cerebellar ependymoma completely located in the brain parenchyma.A previously healthy 32-year-old female with a 1-month history of dizziness was admitted to our *** hospitalization,magnetic resonance imaging of the brain revealed a space-occupying lesion measuring 57 mm×41 mm×51 mm in the right cerebellar hemisphere and inferior cerebellar *** patient underwent surgical resection for the right cerebellar *** pathological examination revealed an *** 1 year follow-up,the patient was doing well and showed no *** We conducted a literature review and summarized three theories regarding ependymomas located exclusively in the brain parenchyma,which are key to the diagnosis of intraparenchymal cerebellar *** and postoperative radiotherapy are the primary treatment options for ependymomas.

关键词： Cerebellar ependymoma Brain parenchyma Mechanisms Surgery Case report

基于脾脏代谢组学研究肿节风总黄酮治疗免疫性血小板减少症的作用机制

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

北京中医药大学学报 2024年第2期47卷 213-222页

作者：卢震尚广彬卢晓南张钟康刘慧珍曾英坚江西中医药大学附属医院南昌330006 江西中医药大学中医基础理论分化发展中心江西中医药大学中医学院

目的运用代谢组学技术研究肿节风总黄酮干预免疫性血小板减少症(ITP)的作用机制。方法48只雄性SD大鼠使用Excel随机函数分为正常对照组,模型组,肿节风总黄酮低、中、高剂量组和醋酸泼尼松龙组,每组8只。除正常对照组外,其他各组大鼠第1... 详细信息

目的运用代谢组学技术研究肿节风总黄酮干预免疫性血小板减少症(ITP)的作用机制。方法48只雄性SD大鼠使用Excel随机函数分为正常对照组,模型组,肿节风总黄酮低、中、高剂量组和醋酸泼尼松龙组,每组8只。除正常对照组外,其他各组大鼠第1、3、4、6、7、8天腹腔注射兔抗大鼠血小板血清(5 mL/kg)复制ITP大鼠模型,正常对照组大鼠腹腔注射等体积生理盐水。造模日同时给药干预,每日1次。肿节风总黄酮低、中、高剂量组分别灌胃肿节风总黄酮(31.5、63.0、94.5 mg/kg),醋酸泼尼松龙组腹腔注射醋酸泼尼松龙(10.0 mg/kg)。第0、3、6、9天检测各组大鼠外周血小板数量,第10天称量脾脏质量,并计算脾脏指数。利用超高效液相色谱-四级杆-飞行时间质谱技术和多元统计分析对各组大鼠脾脏差异代谢物进行筛选和鉴定,并进行通路富集分析。结果与正常对照组比较,模型组大鼠第6、9天外周血小板减少,脾脏质量增加,脾脏系数升高(P<0.05)。与模型组比较,肿节风总黄酮低、中、高剂量组第6、9天外周血小板数量增加,肿节风总黄酮高剂量组脾脏质量减少,肿节风总黄酮中、高剂量组脾脏指数降低(P<0.05)。脾脏代谢组学分析筛选得到24种与ITP相关的生物标志物,肿节风总黄酮高剂量组可以回调其中的21种,主要涉及亚油酸代谢、半胱氨酸和蛋氨酸代谢、甘油磷脂代谢。结论肿节风总黄酮可能通过调节脾脏亚油酸代谢、半胱氨酸和蛋氨酸代谢、甘油磷脂代谢等代谢通路恢复免疫系统的正常调节能力,以抑制血小板过度破坏,发挥治疗ITP的作用。

关键词：肿节风总黄酮免疫性血小板减少症代谢组学脾脏免疫大鼠

基于高职家校社协同育人模式的家长学校建设探究

在线全文

学校读者我要写书评

暂无评论

吉林省教育学院学报 2024年第8期40卷 115-119页

作者：陆璐江苏工程职业技术学院

邀请家长参与高职协同教育,为三全育人提供有效抓手,对促进高职学生健康成长、提升高职院校育人水平具有重要意义。本文探讨了如何在家长学校理念的引领下有效构建高职院校的家校社协同育人模式。通过家庭教育的参与、创新的教育观念以... 详细信息

邀请家长参与高职协同教育,为三全育人提供有效抓手,对促进高职学生健康成长、提升高职院校育人水平具有重要意义。本文探讨了如何在家长学校理念的引领下有效构建高职院校的家校社协同育人模式。通过家庭教育的参与、创新的教育观念以及强化学校、家庭和社会的合作,实现学生全面成长的目标,旨在为相关人员提供参考。

关键词：家长学校高职协同育人

Osteoblast behaviors on titania nanotube and mesopore layers

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Regenerative Biomaterials 2017年第2期4卷 81-87页

作者： Yan Zhang Rong luo Jing Tan Jianxin Wang xiong lu Shuxin Qu Jie Weng Bo Feng Key Laboratory of Advanced Technologies of Materials Ministry of EducationSchool of Materials Science and EngineeringSouthwest Jiaotong UniversityChengdu 610031PR China

Titania nanotubes and mesopores with different diameter sizes were prepared by electrochemical oxidation of *** responses of osteoblastic cells isolated from Sprague–Dawley rats to the nanotube and mesopore layers were investigated in sequential events of cell adhesion,morphology,actin cytoskeleton,proliferation,differentiation,and ***-structural features,especially diameters of the nanotubes and mesopores,obviously influenced on cell behaviors in the sequential *** cells showed better proliferation and differentiation abilities on the specimens with the nanotubes and mesopores than on flat titanium *** levers of calcium mineralization were observed on the nanotube and mesopore *** cells adhered much faster onto the nanotubes with about 170nm diameter and the mesopores with about 400nm diameter than onto flat titanium disk and 50nm *** is an appropriate range of the tube/pore sizes,and in this present work,titania nantubes with 170nm diameter is the best for enhancing functions of osteoblasts.

关键词： nanotube mesopore osteoblast adhesion proliferation mineralization

简约合作治理:环保组织构建垃圾管理模式的实践策略研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

学习与探索 2024年第3期 70-79,176页

作者：刘萌卢春天河海大学社会学系西安交通大学人文与社会科学学院社会学系

新形势下城市生活垃圾存量高、增速快等治理困境,需要依靠社会力量构建行之有效的垃圾管理模式。环保组织是城市基层环境治理主体之一,其参与垃圾管理的实践是重构环境治理多元关系和深化专业领域合作的有益探索。通过对环保组织--成都G... 详细信息

新形势下城市生活垃圾存量高、增速快等治理困境,需要依靠社会力量构建行之有效的垃圾管理模式。环保组织是城市基层环境治理主体之一,其参与垃圾管理的实践是重构环境治理多元关系和深化专业领域合作的有益探索。通过对环保组织--成都GY的个案研究,笔者发现环保组织可以打造人居环境整治和本地化服务平台,并通过发展居民自组织构建起社区环保关系网络,采用代际联动模式夯实治理的信任基础,进而构建起独特的垃圾管理模式。在该模式之下,环保组织形塑了多元主体之间的合作关系,并通过场景教育纾解了合作治理长期开展过程中可能面临的不稳定性,进一步强化了社区内“传统共同体”环保作用的发挥,构筑起社会基础相对稳固的责任共同体。

关键词：环保组织垃圾管理简约合作治理责任共同体