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A comparison study on structure-function relationship of polysaccharides obtained from sea buckthorn berries using different methods:antioxidant and bile acid-binding capacity

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Food Science and Human Wellness 2024年第1期13卷 494-505页

作者： Qiaoyun Li Zuman Dou Qingfei Duan Chun Chen Ruihai Liu Yueming Jiang Bao Yang xiong fu SCUT-Zhuhai Institute of Modern Industrial Innovation School of Food Science and EngineeringSouth China University of Technology381 Wushan RoadGuangzhou 510640China Guangzhou Institute of Modern Industrial Technology Nansha 511458China Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety Guangzhou 510640China Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health(111 Center) Guangzhou 510640China Department of Food Science Stocking HallCornell UniversityIthaca 14853USA South China Botanical Garden Chinese Academy of SciencesGuangzhou 510650China

In this study,the structural characters,antioxidant activities and bile acid-binding ability of sea buckthorn polysaccharides(HRPs)obtained by the commonly used hot water(HRP-W),pressurized hot water(HRP-H),ultrasonic(HRP-U),acid(HRP-C)and alkali(HRP-A)assisted extraction methods were *** results demonstrated that extraction methods had significant effects on extraction yield,monosaccharide composition,molecular weight,particle size,triple-helical structure,and surface morphology of HRPs except for the major linkage *** analysis showed that HRP-U with filamentous reticular microstructure exhibited better thermal *** HRP-A with the lowest molecular weight and highest arabinose content possessed the best antioxidant ***,the rheological analysis indicated that HRPs with higher galacturonic acid content and molecular weight showed higher viscosity and stronger crosslinking network(HRP-C,HRP-W and HRP-U),which exhibited stronger bile acid binding *** present findings provide scientific evidence in the preparation technology of sea buckthorn polysaccharides with good antioxidant and bile acid binding capacity which are related to the structure affected by the extraction methods.

关键词： Sea buckthorn Extraction method Structure Rheological properties Antioxidant activity Bile acid binding capacity

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Effect of an Airbag-selective Portal Vein Blood Arrester on the Liver after Hepatectomy:A New Technique for Selective Clamping of the Portal Vein

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Current Medical Science 2024年第2期44卷 380-390页

作者： Ce-xiong fu Xiao-ri QIN Jin-song CHEN Jie ZHONG Yu-xu XIE Bi-dan LI Qing-qing fu Fang LI Jin-fang ZHENG Department of Hepatobiliary and Pancreatic Surgery Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311China University of South China Hengyang 421001China Department of Gastroenterology Gastroenterology Endoscopy CenterHainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 57031lChina Center of Clinical Laboratory Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311China Department of Radiology Hainan General HospitalHainan Affiliated Hospital of Hainan Medical UniversityHaikou 570311China

Objective:A novel technique was explored using an airbag-selective portal vein blood arrester that circumvents the need for an intraoperative assessment of anatomical variations in patients with complex intrahepatic space-occupying ***:Rabbits undergoing hepatectomy were randomly assigned to 4 groups:intermittent portal triad clamping(PTC),intermittent portal vein clamping(PVC),intermittent portal vein blocker with an airbag-selective portal vein blood arrester(APC),and without portal blood occlusion(control).Hepatic ischemia and reperfusion injury were assessed by measuring the 7-day survival rate,blood loss,liver function,hepatic pathology,hepatic inflammatory cytokine infiltration,hepatic malondialdehyde levels,and proliferating cell nuclear antigen ***:Liver damage was substantially reduced in the APC and PVC *** APC animals exhibited transaminase levels similar to or less oxidative stress damage and inflammatory hepatocellular injury compared to those exhibited by the PVC *** was significantly higher in the control group than in the other *** APC group had less bleeding than the PVC group because of the avoidance of portal vein skeletonization during ***,more operative time was saved in the APC group than in the PVC ***,the total 7-day survival rate in the APC group was higher than that in the PTC ***:Airbag-selective portal vein blood arresters may help protect against hepatic ischemia and reperfusion injury in rabbits undergoing partial *** technique may also help prevent liver damage in patients requiring hepatectomy.

关键词： hepatectomy portal vein hepatic damage selective clamping

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Dendrobium officinale polysaccharide attenuates type 2 diabetes in mice model by modulating gut microbiota and alleviating intestinal mucosal barrier damage

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Food Science and Human Wellness 2024年

作者： Xiaoxia Chen Chun Chen Changyang Ma Wenyi Kang Junlin Wu xiong fu Guangzhou Wondfo Health Science and Technology Co.， Ltd. National R&D Center for Edible fungus Processing Technology， Henan University Guangdong Province Key Laboratory for Green Processing of Natural Products and Product Safety Guangzhou Institute of Modern Industrial Technology 4. Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center) SCUT-Zhuhai Institute of Modern Industrial Innovation， School of Food Science and Engineering， South China University of Technology

The purpose of this study was to investigate the hypoglycemic effect and mechanism of Dendrobium officinale polysaccharide (DOP) on type 2 diabetes mellitus (T2DM) mice established by high-fat diet and streptozotocin. The results showed that DOP improved glycolipid metabolism and serum inflammation levels， and inhibited intestinal-derived lipopolysaccharide (LPS) translocation， suggesting that inhibiting LPS-mediated intestinal barrier damage may be a key target for DOP to alleviate T2DM. Interestingly， the study found that DOP reduced intestinal inflammation and oxidative stress levels， significantly up-regulated the mRNA expression of tight junction proteins Claudin-1， Occludin and Zonula occluden-1 (ZO-1)， and ameliorated intestinal epithelial damage. In addition， DOP strongly inhibited the intestinal pathogenic bacteria and LPS-producing bacteria Helicobacter， Enterococcus and Desulfovibrio with a reduction rate of 95%， 73% and 9%， respectively， and promoted the proliferation of anti-inflammatory bacteria Bifidobacterium and Lactobacillus by 139% and 8%， respectively. Taken together， the hypoglycemic effect of DOP was related to the protection of intestinal mucosal barrier， and its underlying mechanism lied in its excellent anti-inflammatory and gut microbiota-modulatory effects， providing a theoretical basis for developing DOP as a novel prebiotic in functional food for diabetes.

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基于自适应步长策略的A*算法路径规划优化

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南京信息工程大学学报 2024年第2期16卷 164-172页

作者：付雄李涛南京信息工程大学自动化学院南京210044 南京信息工程大学大气环境与装备技术协同创新中心南京210044

针对A*算法求解路径轨迹耗时长、内存占用大等问题,本文提出一种基于自适应步长策略改进A*算法.首先,根据当前点与终点的位置关系,设定寻路方向的优先级顺序,减少不合理方向上的冗余规划计算量;其次,修改到达终点的判断条件,可在轨迹规... 详细信息

针对A*算法求解路径轨迹耗时长、内存占用大等问题,本文提出一种基于自适应步长策略改进A*算法.首先,根据当前点与终点的位置关系,设定寻路方向的优先级顺序,减少不合理方向上的冗余规划计算量;其次,修改到达终点的判断条件,可在轨迹规划时实现路径的跳跃;再次,针对A*算法轨迹规划效率低的问题,提出自适应步长策略;最后,针对内存占用大,以及面对大地图时可能出现的内存溢出问题,提出了八方向搜索法.实验结果表明,相较于原始的A*算法,改进的A*算法在轨迹规划效率上获得了极大的提升,同时内存占用大的问题也得到了很好的解决.

关键词：路径规划 A*算法自适应步长

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粒径和含结合酚不溶性膳食纤维对白芸豆皮体外发酵特性的影响

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食品工业科技 2024年第1期45卷 118-127页

作者：金姝张斌高彤扶雄黄强华南理工大学食品科学与工程学院广东广州510640 广州酒家集团利口福食品有限公司广东广州511445

为揭示不同粒径的白芸豆皮和含结合酚不溶性膳食纤维的体外发酵规律,本研究以白芸豆皮(WS)为原料,经过连续酶法提取得到含结合酚不溶性膳食纤维(IB),采用普通粉碎和超微粉碎方法对其进行改性,获得不同粒径分布的两组样品,利用扫描电子... 详细信息

为揭示不同粒径的白芸豆皮和含结合酚不溶性膳食纤维的体外发酵规律,本研究以白芸豆皮(WS)为原料,经过连续酶法提取得到含结合酚不溶性膳食纤维(IB),采用普通粉碎和超微粉碎方法对其进行改性,获得不同粒径分布的两组样品,利用扫描电子显微镜和激光共聚焦扫描显微镜对其微观形貌进行观察,并通过体外发酵实验和16S rRNA测序探究两组样品的酵解特性及其对肠道菌群组成丰度的影响。实验结果发现样品粒径越小,结合酚越均匀地分散于颗粒表面。WS和IB都具有慢发酵性,且其发酵速率和产酸量均随着粒径的减小而提高,菌群组成分析发现粒径越小的底物对Bacteroides丰度的促进效果也越显著,但是Lachnospira显示出了对较大粒度底物的偏好。结果表明IB可以促进Bacteroides、Bifidobacterium和Ruminococcaceae ruminococcus等有益菌的相对丰度,改善肠道微生物群的组成结构,其益生效应较相同粒径的WS更为显著。本研究可以为膳食纤维益生元效应的研究提供基础和方向,并可以指导膳食纤维的超微粉碎改性和白芸豆皮的综合利用。

关键词：白芸豆皮不溶性膳食纤维结合酚体外发酵超微粉碎粒径

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Virtual machine selection and placement for dynamic consolidation in Cloud computing environment

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Frontiers of Computer Science 2015年第2期9卷 322-330页

作者： xiong fu Chen ZHOU School of Computer Science and Technology Nanjing University of Posts & Telecommunications Nanjing 210003 China

Dynamic consolidation of virtual machines （VMs） in a data center is an effective way to reduce the en- ergy consumption and improve physical resource utilization. Determining which VMs should be migrated from an over- loaded host directly influences the VM migration time and increases energy consumption for the whole data center, and can cause the service level of agreement （SLA）, delivered by providers and users, to be violated. So when designing a VM selection policy, we not only consider CPU utilization, but also define a variable that represents the degree of resource satisfaction to select the VMs. In addition, we propose a novel VM placement policy that prefers placing a migratable VM on a host that has the minimum correlation coefficient. The bigger correlation coefficient a host has, the greater the in- fluence will be on VMs located on that host after the migra- tion. Using CloudSim, we run simulations whose results let draw us to conclude that the policies we propose in this pa- per perform better than existing policies in terms of energy consumption, VM migration time, and SLA violation per- centage.

关键词： cloud computing dynamic consolidation VMmigration energy consumption

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Task scheduling and virtual machine allocation policy in cloud computing environment

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Journal of Systems Engineering and Electronics 2015年第4期26卷 847-856页

作者： xiong fu Yeliang Cang School of Computer Science and Technology Nanjing University of Posts and Telecommunications

Cloud computing represents a novel computing model in the contemporary technology world. In a cloud system, the com- puting power of virtual machines （VMs） and network status can greatly affect the completion time of data intensive tasks. How- ever, most of the current resource allocation policies focus only on network conditions and physical hosts. And the computing power of VMs is largely ignored. This paper proposes a comprehensive resource allocation policy which consists of a data intensive task scheduling algorithm that takes account of computing power of VMs and a VM allocation policy that considers bandwidth between storage nodes and hosts. The VM allocation policy includes VM placement and VM migration algorithms. Related simulations show that the proposed algorithms can greatly reduce the task comple- tion time and keep good load balance of physical hosts at the same time.

关键词： cloud computing resource allocation task scheduling,virtual machine (VM) allocation.

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鸡粪生物炭的制备及其对硒镉伴生酸性土壤的改良效果研究

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中国土壤与肥料 2024年第4期 214-221页

作者：刘瑶胡百顺杜兴媛熊福平邓端富冉福林鄢中妮陈永波恩施土家族苗族自治州农业科学院湖北恩施445000 湖北省地质局第二地质大队湖北恩施445000

为探究鸡粪生物炭(JF-BC)的高效制备及其对恩施地区硒镉伴生酸性土壤改良的效果,通过优化限氧热解技术中温度、时长参数制备高吸附性能鸡粪生物炭,通过为期52 d的室内恒温恒湿土壤培养试验探究不同添加量JF-BC(未添加记作CK,2%添加量记... 详细信息

为探究鸡粪生物炭(JF-BC)的高效制备及其对恩施地区硒镉伴生酸性土壤改良的效果,通过优化限氧热解技术中温度、时长参数制备高吸附性能鸡粪生物炭,通过为期52 d的室内恒温恒湿土壤培养试验探究不同添加量JF-BC(未添加记作CK,2%添加量记作2%BC,4%添加量记作4%BC)对土壤理化性质的影响及动态进程。试验结果表明,热解温度700℃、热解1.5 h,制备的JF-BC产品p H最高,镉吸附性能最优。产品对于4≤pH≤8的Cd^(2+)溶液具有稳定吸附效果,吸附量为244.81~248.22 mg·g^(-1)。2%BC及4%BC处理均使得培养的土壤由酸性提升至中性或弱碱性。培养第3 d,2%BC和4%BC处理有机质、有效磷、速效钾含量较CK显著提升29.19%和56.90%、425.4%和449.09%、884.11%和1475.82%,培养过程中效果稳定持续;培养过程中2%BC处理碱解氮较CK显著提升,4%BC与CK无显著性差异。培养第52 d,4%BC土壤阳离子交换量较CK显著提升45.34%。培养过程中,2%BC及4%BC处理土壤有效镉逐渐降低,较CK最高降低32.32%,4%BC处理有效硒有所增加,较CK最高增加26.47%。JF-BC能有效改善恩施地区土壤的p H、有机质、阳离子交换量等化学性质,提升土壤磷、钾肥力,降低镉的有效性,提高硒的活化率,4%添加量改良效果更佳。但当JF-BC大量施用时,要注意氮素的补充及磷、钾素减量。此研究对改良恩施地区土壤酸化、提高硒利用率并抑制镉迁移转化提供有益探索。

关键词：鸡粪生物炭酸性土壤硒镉伴生土壤化学性质

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Convergence of the Cesaro Mean for Rational Orthonormal Bases

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Acta Mathematica Sinica,English Series 2009年第4期25卷 581-592页

作者： Ying xiong fu Luo Qing LI Key Laboratory of Applied Mathematics Hubei ProvinceFaculty of Mathematics and Computer Science Hubei UniversityWuhan 430062 P. R. China

This paper deals with the convergence of the Cesaro mean for the rational orthonormal bases. Provided the set of zeroes of rational orthonormal bases is formed by a periodic repetition of the same finite sequence, the explicit expression of so-called block-Fejer kernel is available, and some properties of the block-Fejer kernel are discussed. Based on the convergence of the block-Cesaro mean, the convergence of Cesaro mean is also provided.

关键词： Cesaro mean trigonometric series rational orthonormal basis

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慢性肾脏病患者血液透析期间肺部感染病原菌及危险因素

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中华医院感染学杂志 2024年第15期34卷 2278-2281页

作者：顾萍洪花熊付静戴星星张聿江南大学附属医院内分泌肾内科江苏无锡214000

目的探讨慢性肾脏病(CKD)患者血液透析期间肺部感染(PI)的病原菌分布特点与相关危险因素.方法研究对象选自于2018年5月—2022年11月在江南大学附属医院接受治疗的CKD患者,共纳入106例,并对其临床资料进行回顾性分析,根据所选患者血液透... 详细信息

目的探讨慢性肾脏病(CKD)患者血液透析期间肺部感染(PI)的病原菌分布特点与相关危险因素.方法研究对象选自于2018年5月—2022年11月在江南大学附属医院接受治疗的CKD患者,共纳入106例,并对其临床资料进行回顾性分析,根据所选患者血液透析期间是否发生PI将其分为感染组(27例)和未感染组(79例);统计感染组患者病原菌分布特点,比较两组临床资料,CKD患者血液透析期间PI的危险因素予以多因素Logistic回归分析法进行分析.结果感染组27例患者共检出病原菌13株,检出率为48.15%,革兰阳性菌2株,革兰阴性菌7株,真菌4株;感染组心功能分级为Ⅳ级、合并糖尿病、心衰的患者占比分别为44.44%、48.15%、51.85%,均高于未感染组的22.78%、26.58%、30.38%(P<0.05);感染组外周血血红蛋白水平<110 g/L的患者占比为62.96%,均高于未感染组的40.51%;外周血白细胞水平及红细胞分布宽度高于未感染组,血清磷水平低于未感染组(P<0.05);采用多因素Logistic回归分析法分析结果显示,CKD患者血液透析期间PI的危险因素包括合并糖尿病、合并心衰(OR=3.658、2.680,P<0.05).结论CKD患者血液透析期间PI的危险因素包括合并糖尿病、合并心衰,且感染病原菌中革兰阴性菌占比较高,主要为肺炎克雷伯菌,临床可据此给予针对性的预防措施及抗菌治疗.

关键词：慢性肾脏病血液透析肺部感染病原菌危险因素

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