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Spatial perception in the rat auditory cortex

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Spatial perception in the rat auditory cortex

Trehalose and trehalose-hydrolyzing enzyme in the haemolymph of Locusta rnigratoria infected with Metarhizium anisopliae strain CQMa102

中国神经科学学会第十二届全国学术会议

作者： xiong-jie yu Interdisciplinary Institute of Neuroscience and Technology Qiushi Academy for Advanced Studies Zhejiang University

How activity of sensory neurons leads to perceptual decisions remains a challenge to understand. Correlations between choices and single neuron firing rates have been found in visual, vestibular and somatosensory systems. In the auditory system, however, how neuronal activities correlate with auditory perception, for instance, the spatial perception, remains unclear. To investigate choice-related activity, we have recorded from auditory cortex（AC） and auditory thalamus（MGB） while animals performed a fine sound location discrimination task. We find that AC has similar discrimination thresholds as thalamic cells, and the most sensitive neurons have thresholds that are only twofold or threefold greater than perceptual thresholds. The fact that minimum thresholds measured in MGB are of the same order of magnitude as behavioral thresholds suggests that the MGB might determine the limit on our ability to discriminate small differences in sound location, with little noise added during downstream processing. We also tested the hypothesis that spatial tuning sharpens when an animal engages in an auditory task by comparing the neuronal threshold between behavior condition and non-behavior condition. Preliminary data indicated neuronal firing in both AC and MGB neuron were modulated by the task, reflecting a top-down control of dynamic spatial tuning.

关键词： auditory cortex auditory thalamus choice probability attention

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Insect Science 2007年第4期14卷 277-282页

作者： HUA ZHAO ZHONG-KANG WANG YOU-PING YIN YAN-LING LI ZHEN-LUN LI GUO-xiong PENG yu-XIAN XIA GeneticEngineeringResearchCenter CollegeofBioengineeringChongqingUniversityChongqingChina

Topical application of the Metarhizium anisopliae var. acridum specialist strain CQMa 102 to the locust Locusta migratoria manilensis results in changes of the concentrations of trehalose and glucose in the haemolymph. Micrographs of the locust haemolymph shows Metarhizium anisopliae can effectivly penetrate the external skeleton of locust and after 2 days infection, the hyphae body will appear in the haemolymph of infected insects. The time in decrease of trehalose concentration coincided with that in increase of trehalose-hydrolysing enzyme activity in the haemolymph of the fungus-infected insects. Overlay gel analysis indicated there was considerably more trehalose-hydrolysing activity in the haemolymph of locusts infected by fungus than in controls. A comparable isoform was identified in in vitro culture of the fungus, suggesting a fungal origin for the in vivo enzyme. Haemolymph trehalose decreased significantly during mycosis of locusts by M. anisopliae. All these results suggested that this fungus may take advantage of competing nutrient utilization against the insect by its trehalose-hydrolyzing enzyme secretion. It may provide fundamental knowledge for fungal pathogenesis.

关键词： Metarhizium anisopliae Locusta migratoria manilensis trehalose-hydrolysingenzymes trehalose glucose mycosis

Adaptive Polarization Control of Fiber Amplifier Based on SPGD Algorithm

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Chinese Physics Letters 2012年第12期29卷 116-118页

作者： xiong yu-Peng SU Rong-Tao LI Xiao HOU Pu WANG Xiao-Lin XU Xiao-Jun College of Optoelectric Science and Engineering National University of Defense TechnologyChangsha 410073

We demonstrate an adaptive polarization control system of a 10.2 W non-polarization-maintaining fiber amplifier based on stochastic parallel gradient decent(SPGD)*** experimental investigation shows that the system can used to compensate for the polarization fluctuation of the fiber amplifier effectively and perform well over a long-time *** the adaptive polarization control system is in closed loop,the extinction ratio increases from 2.28 dB to 11.54 dB,and more than 93.4%of the total power in desired polarization direction is achieved.

关键词： polarization amplifier fiber

Influence of Cr element on impact fracture process of ductile Ni-resistant alloyed iron at low temperature

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China Foundry 2016年第1期13卷 42-46页

作者： Ke Jiang Ying-dong Qu Jun-hua You Rong-de Li Qing-chun Xiang yu-xiong Zhou School of Materials Science and Engineering Shenyang University of Technology

In this study, in order to investigate the influence of Cr element on the impact fracture process of ductile Ni-resistant alloyed iron at low temperature, different contents of Cr element were added to ductile Ni-resistant(DNR) austenitic alloyed iron. The experimental results show that Cr addition can increase the hardness of the DNR alloyed iron, but it has an destructive effect on low-temperature impact properties. Through the analysis of the dynamic load and absorbed energy of samples with different Cr contents in the impact fracture process, and the comparison of the impact fracture process at room and low temperatures, it reveals that Cr addition into the DNR alloyed iron can facilitate the formation of the carbide mixture in Mn23C6 and Cr23C6 with homogeneous and discontinuous distribution. Meanwhile, Cr addition also can improve the the maximum dynamic load and crack initiation energy at low temperature, but has no obvious effect on the yield behavior of the DNR alloyed iron in the impact fracture process. Compared with the impact crack propagation process at room temperature, the metastable propagation energy at low temperature declines significantly with an increase in Cr content. This is because the micro-cracks that caused by the carbides weaken the matrix, resulting in the decline of impact crack propagation resistance. The fracture analysis results also show that the impact fracture mechanism gradually transforms from ductile to brittle with an increase in Cr content at low temperature. It explains that too much Cr addition can lead to brittle fracture even though the austenitic matrix has a good toughness at low temperature.

关键词： Ni-resistant alloyed iron carbide impact fracture low temperature Cr addition

Postoperative Disc Wedging in Adolescent Idiopathic Thoracolumbar/Lumbar Scoliosis:a Comparison of Anterior and Posterior Approaches

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Chinese Medical Sciences Journal 2010年第3期25卷 156-161页

作者： Bin yu Yi-peng Wang Gui-xing Qiu Jian-guo Zhang Jian-xiong Shen yu Zhao Shu-gang Li Qi-yi Li Department of Orthopedics Peking Union Medical College HospitalChinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730 China

Objective To evaluate the different influences of anterior and posterior correction and fusion approaches upon disc wedging in adolescent idiopathic thoracolumbar/lumbar *** The retrospective study was conducted with the medical records and radiographs of adolescent idiopathic thoracolumbar/lumbar scoliosis patients that underwent anterior(group A) or posterior(group B) correction and fusion surgery from December 1998 to May *** correction of the main curve and changes of the disc wedging were *** Fifty-three patients were included,26 in group A and 27 in group *** mean coronal Cobb angles of the main curve in group A and group B were significantly corrected after surgery(P0.05).The difference between disc wedging at final follow-up and that after surgery was significant in group A(P0.05).Between the two groups,group A had larger disc angles after operation and at final follow-up(P<0.05),and a greater loss of disc angle(P<0.05).Conclusion For adolescent idiopathic thoracolumbar/lumbar scoliosis,posterior approach using all pedicle screws might produce a better result in terms of disc wedging compared with anterior

关键词： adolescent idiopathic scoliosis thoracolumbar/lumbar curve anterior fusion posterior fusion disc wedging

Cardioprotective Potential of Cymbopogon citratus Essential Oil against Isoproterenol-induced Cardiomyocyte Hypertrophy:Possible Involvement of NLRP3 Inflammasome and Oxidative Phosphorylation Complex Subunits

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Current Medical Science 2024年第2期44卷 450-461页

作者： Xiao-yun DING Hao ZHANG yu-mei QIU Meng-die XIE Hu WANG Zheng-yu xiong Ting-ting LI Chun-ni HE Wei DONG Xi-lan TANG School of Pharmacy Jiangxi Science&Technology Normal UniversityNanchang 330013China Key Laboratory of Modern Preparation of Chinese Medicine Ministry of EducationJiangxi University of Chinese MedicineNanchang 330004China Jiangxi Provincial Key Laboratory of Drug Design and Evaluation Nanchang 330013China

Objective:Cymbopogon citratus(DC.)Stapf is a medicinal and edible herb that is widely used for the treatment of gastric,nervous and hypertensive *** this study,we investigated the cardioprotective effects and mechanisms of the essential oil,the main active ingredient of Cymbopogon citratus,on isoproterenol(ISO)-induced cardiomyocyte ***:The compositions of Cymbopogon citratus essential oil(CCEO)were determined by gas chromatography-mass *** were pretreated with 16.9µg/L CCEO for 1 h followed by 10µmol/L ISO for 24 *** hypertrophy-related indicators and NLRP3 inflammasome expression were ***,transcriptome sequencing(RNA-seq)and target verification were used to further explore the underlying ***:Our results showed that the CCEO mainly included citronellal(45.66%),geraniol(23.32%),and citronellol(10.37%).CCEO inhibited ISO-induced increases in cell surface area and protein content,as well as the upregulation of fetal gene ***,CCEO inhibited ISO-induced NLRP3 inflammasome expression,as evidenced by decreased lactate dehydrogenase content and downregulated mRNA levels of NLRP3,ASC,CASP1,GSDMD,and IL-1β,as well as reduced protein levels of NLRP3,ASC,pro-caspase-1,caspase-1(p20),GSDMD-FL,GSDMD-N,and pro-IL-1β.The RNA-seq results showed that CCEO inhibited the increase in the mRNA levels of 26 oxidative phosphorylation complex subunits in ISO-treated *** further experiments confirmed that CCEO suppressed ISO-induced upregulation of mt-Nd1,Sdhd,mt-Cytb,Uqcrq,and mt-Atp6 but had no obvious effects on mt-Col ***:CCEO inhibits ISO-induced cardiomyocyte hypertrophy through the suppression of NLRP3 inflammasome expression and the regulation of several oxidative phosphorylation complex subunits.

关键词： Cymbopogon citratus essential oil cardiac hypertrophy NLRP3 inflammasome oxidative phosphorylation complex subunits

Always My Beloved Wife

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英语学习 1995年第8期 29-31页

作者： xiong Deni yu Zhigang

When alone reflecting on my life,I would sometimes be as-sailed by a thought:My wife should look more *** wife is not *** fact,she has a very pleasant smile,but that’s *** is well in her thirties,so naturally she no

关键词： In Always My Beloved Wife

Alagille syndrome associated with total anomalous pulmonary venous connection and severe xanthomas:A case report

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World Journal of Clinical Cases 2022年第25期10卷 8932-8938页

作者： Han-Shi Zeng Zhan-Hui Zhang Yan Hu Gui-Lang Zheng Jing Wang Jing-Wen Zhang yu-xiong Guo Department of Pediatrics Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510030Guangdong ProvinceChina Department of Pediatrics Clinical Medicine Research InstituteThe First Affiliated HospitalJinan UniversityGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Alagille syndrome(ALGS)is an autosomal dominant genetic disorder caused by mutations in the JAG1 or NOTCH2 *** is characterized by decreased intrahepatic bile ducts associated with a variety of abnormalities in many other organ systems,such as the cardiovascular,skeletal,and urinary *** SUMMARY We report a rare case of ALGS.A 1-month-old male infant presented with sustained jaundice and had a rare congenital heart disease:Total anomalous pulmonary venous connection(TAPVC).Sustained jaundice,particularly with cardiac murmur,caught our *** tests revealed elevated levels of alanine aminotransferase,aspartate aminotransferase,gamma-glutamyl transpeptidase,total bilirubin,and total bile acids,indicating serious intrahepatic *** confirmed the presence of butterfly vertebra at the seventh thoracic *** suggested ALGS,which was confirmed by genetic testing with a c.3197dupC mutation in the JAG1 *** was administered immediately after confirmation of the diagnosis,and cardiac surgery was performed when the patient was 1.5 month *** recovered well after treatment and was discharged at the age of 3 *** the age of two years,the patient returned to our clinic because multiple cutaneous nodules with xanthomas appeared,and their size and number increased over *** We report a unique case of ALGS associated with TAPVC and severe *** study has enriched the clinical manifestations of ALGS and emphasized the association between JAG1 gene and TAPVC.

关键词： Alagille syndrome JAG1 gene Notch signaling pathway Total anomalous pulmonary venous connection Severe xanthomas Case report

Implement of Low Carbon Logistics Park Based on Minimizing Carbon Emissions

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Meteorological and Environmental Research 2012年第1期3卷 63-65页

作者： LI yu-min xiong yu-wei Institute of Management Engineering of Zhengzhou University Zhengzhou 450001China

Based on the development of modem logistics park in China, and with the thought of minimizing carbon emission, the development of Logistics Park was analyzed and the necessity of developing low carbon Logistics Park was proposed. Low carbon emission in Logistics Park was planned. In the end, operation and implementation strategies of low carbon parks were put forward so as to create favorable environment for the re- alization of low carbon emission in Logistics Park.

关键词： Carbon emissions Low carbon Logistics Park Development planning Operation and implementation strategy China