检索结果-南通市图书馆

China CDC weekly 2023年第11期5卷 235-240页

作者： Tingting Qin Xingming Li Mingyu Gu Yao Wang Yutong Yang xinyuan bai Kun Qiao School of Public Health Capital Medical UniversityBeijingChina

Summary What is already known about this topic?The psychological impact of the large-scale infection of the population resulting from the end of lockdown measures in China during the coronavirus disease 2019(COVID-19)pandemic is unknown.What is added by this report?Among all participants,55.7%had depression symptoms,with a significant difference between the infected and non-infected groups,and 30.1%had anxiety.Those who were young,unvaccinated,had lower incomes,and experienced chronic diseases were more likely to experience negative emotions.What are the implications for public health practice?Government officials should take into account the effect of policies on public sentiment during similar public health events and implement tailored community interventions to address any negative sentiment.

关键词： Infect likely Population

Magnetic properties and microstructures of terbium coated and grain boundary diffusion treated sintered Nd-Fe-B magnets by magnetron sputtering

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Rare Earths 2021年第2期39卷 167-173页

作者： Wei Zhu Yang Luo Zilong Wang xinyuan bai Haijun Peng Dunbo Yu National Engineering Research Center for Rare Earth Materials GRINM Group Co.Ltd.Beijing 100088China GRIREM Advanced Materials Co. Ltd.Beijing 100088China General Research Institute for Nonferrous Metals Beijing 100088China

Tb coating on the surface of commercial sintered Nd-Fe-B magnet was prepared by DC magnetron sputtering.The secondary heat treatment was used to regulate the microstructure for the enhancement of coercivity,namely diffusion treatment and annealing treatment.The coercivity increases significantly from 18.3 to 28.0 kOe,the remanence decreases slightly from 14.1 to 14.0 kGs,and the comprehensive magnetic properties are higher than 75(Hcj+(BH)_(max)=76.7).SEM results indicate that,on the one hand,950℃is the optimal diffusion temperature.Lower diffusion temperature results in insufficient diffusion of Tb element.Higher diffusion temperature can lead to the main phase grain growth,the decrease of Nd-rich phase,and forming holes in the magnet.On the other hand,500℃is the optimal annealing temperature.Lower annealing temperature can result in the reduction of Nd-rich phase.Higher annealing temperature can generate the non-defined Nd-rich thin layer between grains.

关键词： Sintered Nd-Fe-B magnets Magnetron sputtering Tb coating Magnetic properties Rare earths

Effects of grain boundary diffusion of PrCu alloy on microstructure and coercivity of hot deformed(Nd,Ce)-Fe-B magnets

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2021年第8期39卷 986-992页

作者： Haijun Peng Dunbo Yu xinyuan bai Xiao Lin Yongjun Mao Zilong Wang Yang Luo National Engineering Research Center for Rare Earth Materials CRINM Group Co.Ltd.Beijing 100088China GRIREM Advanced Materials Co. Ltd.Beijing 100088China General Research Institute for Non/errous Metals Beijing 100088China

The technology of using high abundance rare earth element Ce in permanent magnets has attracted many concerns.In this work,the magnetic properties and microstructures of hot deformed(Nd_(1-x)Ce_(x))_(13.8)Fe_(76.1)Co_(4)Ga_(0.5)B_(5.6) magnets and a selective magnet treated with PrCu grain boundary diffusion process(GBDP) were investigated systematically.It is found that Ce is beneficial to improving the plastic deformation ability of NdFeB magnets.The strongest c-axis orientation is achieved in the HD magnets with Ce concentration of x=0.3,resulting in good comprehensive magnetic properties of B_(r)=13.00 kGs,H_(cj)=10.12 kOe,(BH)_(max)=38.42 MGOe.Based on that,the GBDP was implemented on the magnets with the best orientation using Pr_(68)Cu_(32) ribbons and the magnetic properties of B_(r)=12.87 kGs,H_(cj)=15.65 kOe,(BH)_(max)=37.48 MGOe were obtained.The results of composition distribution and Curie temperature test of the GBDPed magnets illustrate that Pr diffuses into the(Nd,Ce)_(2)(Fe,Co)_(14)B grains to substitute Ce,which not only improves the Curie temperature of the grains,but also enhances the magnetic performance of the magnets.Through GBDP,the thermal stability of magnets has also been improved.

关键词： Nd-Ce-Fe-B GBDP Hot deformation Magnetic properties Microstructure Rare earths

Magnetic properties enhancement of hot-deformed NdFeB magnets by two different methods of CeNdCu diffusion

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2020年第12期38卷 1312-1316页

作者： Guibing Shi Zilong Wang xinyuan bai Wenlong Yan Yang Luo Dunbo Yu National Engineering Research Center for Rare Earth Materials GRINM Group Co.Ltd.Beijing 100088China GRIREM Advanced Materials Co. Ltd.Beijing 100088China General Research Institute for Nonferrous Metals Beijing 100088China

Two different ways were used to control the distribution of cerium for the enhancement of coercivity.One was by coating CeNdCu in the prepared magnet and annealing to make CeNdCu diffuse into the grain boundary to increase the coercivity,the other was by mixing CeNdCu with initial magnetic powders and then preparing the hot-deformed magnet.The SEM-EDS result indicates that cerium diffuses more easily into the main phase by the mixing way,while cerium is mainly distributed in the grain boundary via the coating way.The heat-treatment process may be one of the dominant influencing factors for the distribution of Ce,Multi-steps heat treatment in the mixing way,consisting of hot-pressing,hot-deforming and post heat process,easily introduces Ce into the main phase Nd2 Fe14B,which forms the Ce2 Fe14B shell resulting in the decrease of HA.But the coating way can ensure uniform dispersion of Ce in the grain boundary,which leads to the high coercivity.

关键词： Hot-deformed magnet Coating Mixing CeNdCu Rare earths

Effects of cerium substitution on phase components, microstructures and magnetic properties of Nd-Fe-Ti-B alloy

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2019年第8期37卷 861-864,I0003页

作者： Haijun Peng Yang Luo Yakun Dou xinyuan bai Wenlong Yan Dunbo Yu Yuanfei Yang Shulin Diao National Engineering Research Center for Rare Earth Materials General Research Institute for Nonferrous MetalsGrirem Advanced Materials Co.Ltd.Beijing 100088China Tianhe(Baotou)Advanced Tech Magnet Co. Ltd.Baotou 014010China

(Nd(1-x)Cex)(12)Fe(77)Ti5B6(x=0,0.2,0.3,0.4,0.6,0.8)alloys were prepared by melt-spinning and annealing techniques.The phase constitutions,microstructures and magnetic properties were investigated by powder X-ray diffraction(XRD),a differential scanning calorimeter(DSC),a vibrating sample magnetometer(VSM)and a transmission electron microscope(TEM).It is found that with the increase of Ce content,the coercivity of the(Nd(1-x)Cex)(12)Fe(77)Ti5B6 alloys reaches maximum first and then decreases.The maximum coercivity reaches 18.5 kOe obtained in the sample of 20%Ce substituted which is 34%higher than the Ce-free sample.TEM results reveal that the micro structure refinement effect is responsible for the coercivity improvement.This phenomenon implies that in some cases,Ce and Ti co-doping is more beneficial to improving of the coercivity than Ti single doping in Nd-Fe-B alloys.With further Ce addition,magnetic properties deteriorate due to the formation of CeFe2 and TbCu7-type phases.

关键词： Melt spun Nd-Ce-Fe-Ti-B Coercivity Microstructure refinement Magnetic Rare earths

马乳酒样乳杆菌马乳酒样亚种real-time PCR检测方法的建立与应用

在线全文

学校读者我要写书评

暂无评论

食品科学 2024年第9期45卷 102-108页

作者：吕厚姣李欣媛白小佳贾龙刚耿伟涛王艳萍天津科技大学食品科学与工程学院天津300457

本研究建立了一种特异性实时聚合酶链式反应(real-time polymerase chain reaction,real-time PCR)检测方法,根据模式菌株马乳酒样乳杆菌马乳酒样亚种ZW3的16S rDNA序列和全基因组序列设计筛选特异性引物,采用SYBR Green I荧光染料建立r... 详细信息

本研究建立了一种特异性实时聚合酶链式反应(real-time polymerase chain reaction,real-time PCR)检测方法,根据模式菌株马乳酒样乳杆菌马乳酒样亚种ZW3的16S rDNA序列和全基因组序列设计筛选特异性引物,采用SYBR Green I荧光染料建立real-time PCR方法,并对方法的特异性、灵敏度、重复性和混合体系等进行检测。结果表明,本研究所建立的方法特异性强、灵敏度高、重复性好,建立real-time PCR的标准曲线,其决定系数R2为0.965,具有良好的线性关系,且在马乳酒样乳杆菌马乳酒样亚种及混合体系中可以特异性检出。综上,本研究建立的real-time PCR法可以快速、准确地检测马乳酒样乳杆菌马乳酒样亚种,为马乳酒样乳杆菌的特异性定性定量检测提供了一种新的方法。

关键词：马乳酒样乳杆菌马乳酒样亚种实时聚合酶链式反应特异性引物

空调温控负荷集群参与光伏消纳的潜力评估与互动框架

在线全文

学校读者我要写书评

暂无评论

现代电力 2024年第3期41卷 479-489页

作者：陈璨杜维柱白恺孙贝贝孙靓付新园吴俊勇国网冀北电力有限公司电力科学研究院北京市西城区100045 国网冀北电力有限公司北京市西城区100052 北京交通大学电气工程学院北京市海淀区100044

空调温控负荷集群作为当下最具调节潜力的需求侧响应资源之一,在削峰、填谷、分布式光伏消纳和电网调控中将发挥重要作用。因此,提出一种电力市场环境下,基于数据驱动和深度置信网络的空调温控负荷集群参与分布式光伏消纳的可调节潜力... 详细信息

空调温控负荷集群作为当下最具调节潜力的需求侧响应资源之一,在削峰、填谷、分布式光伏消纳和电网调控中将发挥重要作用。因此,提出一种电力市场环境下,基于数据驱动和深度置信网络的空调温控负荷集群参与分布式光伏消纳的可调节潜力评估与互动框架。首先,利用数据驱动构建了基于深度置信网络的可调节潜力评估模型,实时输出温控负荷集群的可调节潜力;其次,考虑功率调整量在一定范围内变化的前提下,构建基于深度置信网络的需求互动模型,对温控负荷集群进行实时温度调控。最后,以冀北地区某10kV馈线作为实际算例进行分析,结果表明:所提框架能够充分利用空调温控负荷集群的可调节潜力,参与分布式光伏的消纳。

关键词：空调温控负荷集群数据驱动深度置信网络潜力评估需求互动

基于半结构化访谈法的卫生体系视角下我国基层高血压管理模式的实施现状、问题分析及政策建议

在线全文

学校读者我要写书评

暂无评论

中国全科医学 2024年第13期27卷 1544-1549页

作者：王尧秦廷廷谷明宇白欣苑乔昆杨宇彤李星明首都医科大学公共卫生学院北京市100069

背景高血压是影响我国居民健康的常见慢性非传染性疾病,基层作为高血压管理与控制的重要关口,其管理能力直接影响着管理效果。现阶段我国基层高血压管理模式运作现状和共性规律仍有待进一步探究。目的了解我国基层高血压管理现状,梳理... 详细信息

背景高血压是影响我国居民健康的常见慢性非传染性疾病,基层作为高血压管理与控制的重要关口,其管理能力直接影响着管理效果。现阶段我国基层高血压管理模式运作现状和共性规律仍有待进一步探究。目的了解我国基层高血压管理现状,梳理典型经验,为我国高血压管理优化提供建议。方法2021年11—12月,对我国五省市29名高血压管理利益相关者进行半结构化访谈,以世界卫生组织卫生体系理论为指导,从领导治理、服务提供、卫生人力、卫生筹资、药物和设备可及性以及卫生信息系统6个维度进行分析。结果在领导治理层面:基层高血压管理工作的开展主要依托于家庭医生签约服务,并需要医疗机构与公共卫生等多部门协同管理;在服务提供层面:基层医疗卫生机构需提供全专融合服务以满足患者个性化医疗需求;在卫生人力层面:社区全科医生是基层高血压管理工作开展的主力,应通过绩效考核按劳分配提升其工作积极性;在卫生筹资方面:高血压患者在基层就诊可获得医保报销倾斜性政策支持;在药物和设备可及性方面:基本医疗设备及高血压基本用药在基层均有配备;在卫生信息系统方面:区域医疗卫生信息平台可实现签约患者健康信息共享与服务协同。结论基层医疗卫生机构承担着对高血压患者长期随访管理的工作,可通过进一步提升基层卫生综合治理能力与基层卫生服务供给能力,加强基层卫生人员能力建设,完善医保报销与支付方式制度,改善基层高血压治疗的药物和设备条件,并通过信息化建设有效赋能基层高血压管理,进一步提升基层高血压管理水平。

关键词：高血压卫生体系基层医疗卫生机构全科医生基层高血压管理慢性病管理半结构化访谈

在线全文

学校读者我要写书评

暂无评论

中国医学装备 2024年第2期21卷 98-103页

作者：张馨元付永峰白立立杨森董立新秦皇岛市第一医院肿瘤科秦皇岛066000 秦皇岛市第一医院烧伤整形美容外科秦皇岛066000

目的:探讨细胞有丝分裂前期检查点(CHFR)和结肠癌转移相关蛋白1(MACC1)表达与直肠癌新辅助同步放化疗(nCRT)敏感性关系。方法:收集2017年3月至2022年2月秦皇岛市第一医院住院治疗的166例直肠癌患者病案资料,所有患者术前仅接受nCRT,其... 详细信息

目的:探讨细胞有丝分裂前期检查点(CHFR)和结肠癌转移相关蛋白1(MACC1)表达与直肠癌新辅助同步放化疗(nCRT)敏感性关系。方法:收集2017年3月至2022年2月秦皇岛市第一医院住院治疗的166例直肠癌患者病案资料,所有患者术前仅接受nCRT,其中放疗采用三维适形调强放疗,化疗采用Capeox方案,nCRT治疗4~6周后均顺利完成腹腔镜下全直肠系膜切除术。免疫组织化学SP染色法检测直肠癌及其癌旁组织CHFR和MACC1蛋白表达。根据美国癌症分期联合委员会肿瘤退化分级(TRG)标准,将nCRT后肿瘤退化分级(TRG)0~2级的75例患者纳入nCRT不敏感组,TRG为3~4级的91例患者纳入nCRT敏感组,比较两组患者治疗前后癌组织CHFR和MACC1蛋白表达水平,分析患者临床病理特征与nCRT敏感性关系,以及nCRT敏感性的影响因素。采用受试者工作特征(ROC)曲线下面积(AUC)分析CHFR和MACC1对直肠癌nCRT敏感性的预测价值。结果:直肠癌组织CHFR阳性表达率显著低于癌旁组织,MACC1阳性表达率显著高于癌旁组织(x^(2)=81.373、87.150,P<0.05)。166例患者nCRT治疗结束后,TRG为0级6例,1级8例,2级61例,3级59例,4级32例,nCRT敏感率为54.82%(91/166)。nCRT敏感组CHFR阳性表达率显著高于nCRT不敏感组,MACC1阳性表达率显著低于nCRT不敏感组(x^(2)=4.613、37.509,P<0.05)。nCRT敏感组T4分期占比高于nCRT不敏感组,N+分期占比高于nCRT不敏感组,差异有统计学意义(x^(2)=54.432、28.912,P<0.05)。CHFR和MACC1表达是影响直肠癌患者对nCRT敏感性的独立危险因素[OR=2.456(95%CI:1.294~4.563),OR=3.281(95%CI:1.472~6.479),P<0.05]。CHFR和MACC1联合检测预测直肠癌nCRT敏感性的灵敏度、特异度分别为65.89%和69.46%,联合检测预测、CHFR和MACC1单项检测的AUC分别为0.713,0.564和0.589,P<0.05。结论:CHFR和MACC1与直肠癌nCRT敏感性有关,即CHFR高表达和MACC1低表达患者对nCRT敏感性更高,故两者有可能成为预测直肠癌nCRT敏感性的指标。

关键词：直肠癌新辅助同步放化疗细胞有丝分裂前期检查点结肠癌转移相关蛋白1 敏感性

Supramolecular nanoscale drug-delivery system with ordered structure

在线全文

学校读者我要写书评

暂无评论

National Science Review 2019年第6期6卷 1128-1137页

作者： Xin Jin Lijuan Zhu bai Xue xinyuan Zhu Deyue Yan School of Chemistry and Chemical Engineering State Key Laboratory of Metal Matrix Composites Shanghai Jiao Tong University

Supramolecular chemistry provides a means to integrate multi-type molecules leading to a dynamic organization. The study of functional nanoscale drug-delivery systems based on supramolecular interactions is a recent trend. Much work has focused on the design of supramolecular building blocks and the engineering of supramolecular integration, with the goal of optimized delivery behavior and enhanced therapeutic effect. This review introduces recent advances in supramolecular designs of nanoscale drug delivery. Supramolecular affinity can act as a main driving force either in the self-assembly of carriers or in the loading of drugs. It is also possible to employ strong recognitions to achieve self-delivery of drugs. Due to dynamic controllable drug-release properties, the supramolecular nanoscale drug-delivery system provides a promising platform for precision medicine.

关键词： supramolecular chemistry drug-delivery system host–guest recognition self-delivery system precision medicine