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Principal component analysis and belief-rule-base aided health monitoring method for running gears of high-speed train

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Science China(Information Sciences) 2020年第9期63卷 281-283页

作者： Chao CHENG xinyu qiao Wanxiu TENG Mingliang GAO Bangcheng ZHANG Xiaojing YIN Hao LUO School of Computer Science and Engineering Changchun University of Technology National Engineering Laboratory CRRC Changchun Railway Vehicles Co. Ltd. Department of Automation Tsinghua University School of Mechatronic Engineering Changchun University of Technology Academy of Astronautics Harbin Institute of Technology

Dear editor,We propose a data-driven health monitoring method for running gears of a high-speed train. In the proposed approach, the principal component analysis (PCA) method is used to perform feature extraction while the belief-rule-base (BRB)method is used to perform health monitoring tasks. To improve the monitoring performance,

关键词： running gears health estimation principle component analysis belief rule base constraint covariance matrix adaptive evolution strategy

In vitro and in silico analysis of dual-function peptides derived from casein hydrolysate

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Food Science and Human Wellness 2021年第1期10卷 32-37页

作者： Maolin Tu xinyu qiao Cong Wang Hanxiong Liu Shuzhen Cheng Zhe Xu Ming Du School of Food Science and Technology National Engineering Research Center of SeafoodCollaborative Innovation Center of Seafood Deep ProcessingDalian Polytechnic UniversityDalian 116034China

There is no study on food-derived peptide with both anticoagulant and angiotensin I-converting enzyme inhibitory (ACEI) activities yet. In this work, the anticoagulant and ACEI activities of the casein hydrolysates released by pepsin digestion were evaluated for the first time to the best of our knowledge. Results indicated that the casein hydrolysate exhibited potent anticoagulant activity by prolonging the thrombin time (TT) and the activated partial thromboplastin time (APTT). Compared with control samples, at 10 mg/mL, the TT and APTT of casein hydrolysate were 186.0 % ± 6.6 % and 163.5 % ± 7.4 %, respectively. The casein hydrolysate also showed a strong ACEI activity with an IC50 value of 1.775 mg/mL. The components of the bioactive casein hydrolysate were analyzed by nanoscale liquid chromatography quadrupole time-of-flight tandem mass spectrometry (NanoLC-Q-TOF-MS/MS). Total of 115 peptides were identified, among which 34, 9, 55 and 17 peptides were derived from α_(s1-), α_(s2-), β-, and κ-casein, respectively. The results of PeptideRanker and PepSite 2 analysis showed that 6 peptides (FRQFYQL, NENLLRF, NPWDQVKR, PVVVPPFLQ, PVRGPFPIIV, and ARHPHPHLSF) have both ACEI and anticoagulant activities by binding to the active sites of ACE and thrombin. This study indicated that casein is a potential functional food supplement that can be used for medical purposes.

关键词： Casein Anticoagulant ACE inhibitory Dual-function NanoLC-Q-TOF-MS/MS

Targeted mutagenesis in Arabidopsis thaliana using CRISPR-Casi2b/C2ci^°°

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Journal of Integrative Plant Biology 2020年第11期62卷 1653-1658页

作者： Fan Wu xinyu qiao Yafei Zhao Ziyi Zhang Yifan Gao Lingfeng Shi Haokun Du Lulu Wang Ya-Jie Zhang Yu Zhang Langyu Liu Quan Wang Dejing Kong School of Biological Science and Engineering Hebei University of Science and TechnologyShijiazhuang 050018China College of Life Sciences Capital Normal UniversityBeijing 100048China Lingnan Laboratory of Modern Agriculture Genome Analysis Laboratory of the Ministry of AgricultureAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518120China State Key Laboratory Breeding Base-Hebei Province Key Laboratory of Molecular Chemistry for Drug Shijiazhuang 050018China

Casi2b/C2ci is a newly identified class 2 CRISPR endonuclease that was recently engineered for targeted genome editing in mammals and *** explore the potential applications of the CRISPR-Casi2b system in the dicot Arabidopsis thaliana,we selected BvCasi2b and BhCasi2b v4 for *** successfully used both endonucleases to induce mutations,perform multiplex genome editing,and create large deletions at multiple *** significant mutations were detected at potential off-target *** of the insertion/deletion frequencies and patterns of mutants generated via targeted gene mutagenesis highlighted the potential utility of CRISPRCasi2b systems for genome editing in Arabidopsis.

关键词： rice. CRISPR Arabidopsis

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基于扫掠法的六面体网格生成算法及实现

南京航空航天大学学报 2007年第1期39卷 71-74页

作者：翟建军乔新宇丁秋林南京航空航天大学机电学院南京210016

提出了一种基于扫掠法的六面体网格生成算法,该算法通过源和目标曲面参数域间的近似最小二乘仿射映射将源曲面的网格投影到目标曲面,并利用背景网格插值的方法计算内结点,从而将2.5维实体生成六面体网格。该算法避免了空间网格投影过程... 详细信息

提出了一种基于扫掠法的六面体网格生成算法,该算法通过源和目标曲面参数域间的近似最小二乘仿射映射将源曲面的网格投影到目标曲面,并利用背景网格插值的方法计算内结点,从而将2.5维实体生成六面体网格。该算法避免了空间网格投影过程中耗时的“寻根”过程,并且不需要导致效率降低的网格优化,能够处理各种2.5维实体,生成的网格质量较好。

关键词：扫掠法六面体网格网格生成 2.5维实体

1937年民国出版业的微观考察:基于商务印书馆开封分馆往来信件

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出版发行研究 2023年第4期 100-105,99页

作者：张国伟乔新玉河南大学新闻与传播学院复旦大学新闻学院河南大学影视艺术研究所

民国出版业借助图书产品和行业理念等参与和推动了中国近现代的知识生产传播。商务印书馆作为彼时出版业的领导者,它的经营活动具有重要意义。本文即以一批新发现的商务印书馆分馆的信函档案为基础,对书信承载的图书购买、书刊宣介、账... 详细信息

民国出版业借助图书产品和行业理念等参与和推动了中国近现代的知识生产传播。商务印书馆作为彼时出版业的领导者,它的经营活动具有重要意义。本文即以一批新发现的商务印书馆分馆的信函档案为基础,对书信承载的图书购买、书刊宣介、账务收支、同行交际以及管理制度等信息进行解读,分析开封分馆的经营活动,以管窥商务印书馆的出版经营管理之体系,并丰富民国出版业之历史概貌。

关键词：商务印书馆开封分馆图书销售业务管理

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基于改进微梁理论的空间柔性机械臂建模方法

华中科技大学学报（自然科学版） 2023年第12期51卷 110-116页

作者：乔鑫宇周文雅刘久钦高旭光大连理工大学航空航天学院辽宁大连116024

针对传统Cosserat梁模型中运动学方程组变量冗余、并非独立及模型中材料模量设定方法不明确的问题,提出一种基于方向余弦阵的Cosserat梁运动学方程简化形式和一种基于多项式拟合的模量设定方法.改进后的建模方法不仅具有更高的模型求解... 详细信息

针对传统Cosserat梁模型中运动学方程组变量冗余、并非独立及模型中材料模量设定方法不明确的问题,提出一种基于方向余弦阵的Cosserat梁运动学方程简化形式和一种基于多项式拟合的模量设定方法.改进后的建模方法不仅具有更高的模型求解效率,而且求解结果可以更加准确地反映超弹性材料属性.数学仿真及有限元分析验证结果表明:所提出的模量设定方法能够很好地反映柔性臂稳态弯曲形状,同时算法的求解时间得到了较为明显的减少.

关键词： Cosserat梁模型稳态分析方向余弦阵模量多项式拟合空间柔性机械臂

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对测量不确定度定义的探讨

焦作大学学报 2020年第2期34卷 97-99页

作者：乔新愚工业和信息化部电子第五研究所计量检测中心广州510610

文章针对当前测量不确定度定义不完善之处(仅仅表示测量值分散性,没有指出被测量真值与测量不确定度之间的关系,从而影响不确定度的理论发展和实际应用),通过深入分析、严谨论证,提出准确完善的测量不确定度定义(表征被测量值分散性的... 详细信息

文章针对当前测量不确定度定义不完善之处(仅仅表示测量值分散性,没有指出被测量真值与测量不确定度之间的关系,从而影响不确定度的理论发展和实际应用),通过深入分析、严谨论证,提出准确完善的测量不确定度定义(表征被测量值分散性的非负参数,被测量真值大概率分布在测得值与该参数确定的区间之内),对正确认识测量不确定度、更好应用测量不确定度具有重要指导意义。

关键词：计量学测量不确定度定义真值分布区间