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Gas expansion caused by formation uplifting and its effects on tight gas accumulation:A case study of Sulige gas field in Ordos Basin,NW China

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Petroleum Exploration and Development 2022年第6期49卷 1266-1281页

作者： LI Jun ZHAO Jingzhou WEI xinshan SHANG Xiaoqing WU Weitao WU Heyuan CHEN Mengna School of Earth Sciences and Engineering Xi’an Shiyou UniversityXi’an 710065China Shanxi Key Lab of Petroleum Accumulation Geology Xi’an Shiyou UniversityXi’an 710065China Research Institute of Exploration and Development Changqing Oilfield CompanyPetroChinaXi’an 710065China

Gas expansion caused by significant exhumation in the Sulige gas field in the Ordos Basin since Late Cretaceous and its effects on hydrocarbon accumulation have been investigated systematically based on comprehensive analysis of geochemical,fluid inclusion and production *** results indicate that gas volume expansion since the Late Cretaceous was the driving force for adjustment and secondary charging of tight sandstone gas reservoirs in the Sulige gas field of the Ordos *** gas retained in the source rocks expanded in volume,resulting in gas re-expulsion,migration and secondary charging into reservoirs,while the gas volume expansion in the tight reservoirs caused the increase of gas saturation,gas-bearing area and gas column height,which worked together to increase the gas content of the reservoir and bring about large-scale gas accumulation *** Sulige gas field had experienced a two-stage accumulation process,burial before the end of Early Cretaceous and uplifting since the Late *** the burial stage,natural gas was driven by hydrocarbon generation overpressure to migrate and accumulate,while in the uplifting stage,the gas volume expansion drove internal adjustment inside gas reservoirs and secondary charging to form new *** the whole,the gas reservoir adjustment and secondary charging during uplifting stage is more significant in the eastern gas field than that in the west,which is favorable for forming gas-rich area.

关键词： uplifting erosion and unloading abnormal pressure gas volume expansion adjustment of gas reservoir secondary charging two-stage accumulation Sulige gas field Ordos Basin

Distribution and depositional model of microbial carbonates in the Ordovician middle assemblage,Ordos Basin,NW China

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Petroleum Exploration and Development 2021年第6期48卷 1341-1353页

作者： WEI Liubin ZHAO Junxing SU Zhongtang WEI xinshan REN Junfeng HUANG Zhengliang WU Chunying State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Chengdu 610059China Institute of Sedimentary Geology Chengdu University of TechnologyChengdu 610059China Exploration and Development Research Institute of PetroChina Changqing Oilfield Company Xi’an 710018China National Engineering Laboratory for Exploration and Development of Low-Permeability Oil&Gas Fields Xi’an 710018China

Based on outcrop profiles,drilling cores,cast thin sections etc.,the types,microfacies combinations and distribution pattern of microbial carbonates in the Ordovician middle assemblage of the mid-eastern Ordos Basin have been systematically *** middle assemblage of Ordovician in the mid-eastern Ordos Basin has microbial carbonates formed by the calci-fication of cyanobacteria,including microbial biostromes and microbial mounds made of stromatolites,thrombolites,and *** distribution of the carbonates shows obvious“stratum-control”and“regional”*** microbial bio-stromes 2–3 m thick each are controlled by sequence cycles and sedimentary facies changes,and were mainly formed in the tidal flat environment during the depositional stages of the Ma56 and Ma55 *** microbial biostrome in the Ma55 sub-member occurring near the carbonate-evaporite transition interface in the early stage of the transgression is distributed mainly in the Mizhi subsag in the eastern part of the basin;the microbial biostrome in the Ma56 sub-member turns up near the carbonate-evoporite transition zone in ring shape in the east of the central *** ancient landform had noticeable control on the distribution of microbial *** microbial mounds or mound-shoal complexes developing mainly during the de-positional stages of Ma57_Ma510 sub-members are about 15–25 m thick in single layer and distributed largely in the Wushenqi-Jingbian *** development model of the microbial carbonate rocks shows that the carbonate-evaporite lithologic transition zone and the Wushenqi-Jingbian paleouplift are favorable exploration zones of microbial carbonates in the Ordovician middle assemblages.

关键词： Ordos Basin Ordovician Majiagou Formation microbial carbonates stromatolite thrombolite oncolite deposi-tional model

Nitrate removal to its fate in wetland mesocosm filled with sponge iron:Impact of influent COD/N ratio

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Frontiers of Environmental Science & Engineering 2020年第1期14卷 77-85页

作者： Zhihao Si xinshan Song Xin Cao Yuhui Wang Yifei Wang Yufeng Zhao Xiaoyan Ge Awet Arefe Tesfahunegn College of Environmental Science and Engineering State Environmental Protection Engineering Center for Pollution Treatment and Control in Textile IndustryDonghua UniversityShanghai 201620China

Sponge iron(s-Fe°)is a porous metal with the potential to be an electron donor for *** study aims to evaluate the feasibility of using s-Fe as the substrate of wetland ***,wetland mesocosms with the addition of s-Fe"particles(CW-Fc)and a blank control group(CW-CK)were *** NOj-N reduction property and water quality parameters(*** ORP)were examined at three COD/N ratios(*** 10).Results showed that the NO3--N removal efficiencies were significantly increased by 6.6 to 58.9%in the presence of s-Fe NH4+-N was mainly produced by chemical denitrification,and approximately 50% of the NO3--N was reduced to N4+-N,at the COD ratio of *** increase of the influent COD/N ratio resulted in lower chemical denitrification and higher *** chemical denitrification mediated by s-Fe led to an accumulation of NH4+-N at COD/N ratios of 0 and *** TIN removal efficiencies increased by 4.5#12.4#.Moreover,the effluent pll,*** ORP values showed a significant negative correlation with total Fe and Fe(II)(P<0.01).High-throughput sequencing analysis indicated that Trichococctis(77.2%)was the most abundant microorganism in the CW-Fc mcsocosm,while Thauera,*** Herbaspirillum were the primary denitrifying *** denitrifiers,Simplicispira,IXxhloronwnas,and *** the dominant bacteria for *** study provides a valuable method and an improved understanding of NOj-N reduction characteristics of s-Fc in a wetland mcsocosm.

关键词： Sponge iron Wetland mesocosm Electronic donor Denitrification COD/N ratio

Sudden death due to arrhythmogenic right ventricular cardiomyopathy: Two case reports

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Frontiers of Medicine 2007年第3期1卷 338-342页

作者： CHEN xinshan ZHANG Yigu RAO Guangxun HUANG Guangzhao Department of Forensic Pathology Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Arrhythmogenic right ventricular cardiomyopathy(ARVC)is a kind of primary myocardial disease characterized by the regional or global replacement of right ventricular myocardium by fatty and fibrolipomatous *** ARVC,usually presenting with different clinical manifestations and pathological changes,were mainly seen in young men and is one of the main causes of sudden death in the *** two autopsied cases of Chinese men aged 30 and 23 years old who appeared healthy but died suddenly while at work are reported *** of the victims had extensive and severe pathological changes in his heart involving the left ventricular wall as well as the ventricular septum and the right *** only was there a global fatty and fibrolipomatous tissue replacement of the right ventricular myocardia,but also mild sarcoplasmic coagulation in the myocardium and focal lymphocytic infiltration in the myocardial interstitium of the right ventricular *** addition,slight atherosclerosis of the coronary artery and intimal thickening of the sino-atrial node were *** is believed that there are no marked differences in the pathological changes of ARVC between Chinese patients and patients from western *** etiology and pathogenesis of ARVC could not be explained by a single cause or factor and they are probably related to various congenital and acquired causes or factors.

关键词： cardiomyopathies death,sudden,cardiac fibrolipomatous tissue

Paleogeomorphy evolution of the Ordovician weathering crust and its implication for reservoir development,eastern Ordos Basin

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Petroleum Research 2018年第1期3卷 77-89页

作者： xinshan Wei Junfeng Ren Junxing Zhao Daofeng Zhang Shunshe Luo Liubin Wei Juanping Chen National Engineering Laboratory for Exploration and Development of Low-Permeability Oil&Gas Fields Shaanxi 710018China Research Institute of Exploration and Development PetroChina Changqing Oilfield CompanyShaanxi 710018China Institute of Sedimentary Geology Chengdu University of TechnologySichuan 610059China Yangtze University Hubei 434100China

Gas reservoir development of the Ordovician weathering crust in the Ordos Basin is closely controlled by the pre-Carboniferous *** studies show that the paleogeomorphy is high in the west and low in the east,and the karst highland,karst slope and karst basin are developed from west to *** further exploration in recent years,many karst breccia that represent strong karstification,are found in the east area which previously is considered to be the Ordovician karst ***,it is necessary to revaluate controlling factors of karst paleogeomorphy development from a viewpoint of the dynamic paleogeomorphy evolution,to investigate the paleogeomorphy evolution of the Ordovician weathering crust in geological history and guide further research and prediction of development law of reservoir *** order to reconstruct the paleogeomorphy of the weathering crust in the top of Ordovician in the east Ordos Basin,paleogeography,thickness of residual strata and paleokarst characteristics are well *** result shows that a wide range of paleokarst highland occurred in the central to east part of Ordos Basin in the early period,and the karst reservoir spaces were formed;but in the late period,the east part of the basin gradually evolved into the paleokarst basin,the current pre-Carboniferous paleogeomorphy was thus formed,and the dissolution reservoir spaces formed in the early period were mostly filled,accordingly the reservoirs were *** fracture networks formed by cave collapse connect intercrystalline pores of dolomite,therefore,the reservoirs can still be well preserved locally and are worthy targets for hydrocarbon exploration.

关键词： The Ordovician weathering crust Paleogeomorphy Karst highland Karst slope Karst basin Karst reservoir Majiagou Formation The eastern Ordos Basin

Design, Synthesis and Biological Activities of N-（Furan-2-ylmethyl）-lH-indole-3-carboxamide Derivatives as Epidemal Growth Factor Receptor Inhibitors and Anticancer Agents

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Chemical Research in Chinese Universities 2017年第3期33卷 365-372页

作者： ZHANG Lan DENG xinshan WU Jiaofeng MENG Guangpeng LIU Congchong CHEN Guzhou ZHAO Qingchun HU Chun Key Laboratory of Structure-based Drug Design & Discovery Ministry of Education Shenyang Pharmaceutical University Shenyang 110016 P. R. China Department of Pharmacy General Hospital of Shenyang Military Area Command Shenyang 110016 P. R. China

A series ofN-（furan-2-ylmethyl）-lH-indole-3-carboxamide derivatives（6a--6p） was designed and synthe- sized for developing novel indole scaffolds as anticancer agents targeting the epidemal growth factor receptor （EGFR）, and the cytotoxic activities of the target compounds were evaluated against three EGFR high-expressed cancer cell lines[human lung adenocarcinoma cell line（A549）, Henrietta Lacks strain of cancer cell line（HeLa） and human colorectal cancer cell line（SW480）], one EGFR low-expressed cell line（human liver cancer cell line, HepG2） and one human liver normal cell line（HL7702） using 3-（4,5-dimethylthiazol-2-yl）-2,5-diphenyl tetrazolium bromide （MTT） assay, Some target compounds exhibited potent anficancer activities against A549, HeLa, SW480 and weak activities on HepG2, which signifies that the target compounds are likely to be EGFR inhibitors as expected. And they showed weak cytotoxic effects on HL7702, which implies the target compounds are probably to be of low toxicity against normal cells. Among them, the target compound 1-ethyl-N-（fttran-2-ylmethyl）-5-{2-{ [2-（2-methoxy- phenoxy）ethyl]amino}-2-oxoethoxy}-2-methyl-1H-indole-3-carboxamide（6p） with 2-{[2-（2-methoxyphenoxy）ethyl]- amino}-2-oxoethoxy group at the C5 position of the N-（furan-2-ylmethyl）-lH-indole-3-carboxamide scaffold exhibited the most potent anticancer activity. Also the binding interaction of the target compound 6p with EGFR was explored by molecular docking. Conclusively, the novel indole scaffold may be beneficial to investigate new anticancer agents for targeting the EGFR.

关键词： Anticancer activity Epidemal growth factor receptor(EGFR) inhibitor N-(Furan-2-ylmethyl)-lH-indole-3-carboxamide derivative

Improved Social Emotion Optimization Algorithm for Short-Term Traffic Flow Forecasting Based on Back-Propagation Neural Network

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Journal of Shanghai Jiaotong university(Science) 2019年第2期24卷 209-219页

作者： ZHANG Jun ZHAO Shenwei WANG Yuanqiang ZHU xinshan School of Electrical Engineering and Automaton Tianjin University

The back-propagation neural network(BPNN) is a well-known multi-layer feed-forward neural network which is trained by the error reverse propagation algorithm. It is very suitable for the complex of short-term traffic flow forecasting; however, BPNN is easy to fall into local optimum and slow convergence. In order to overcome these deficiencies, a new approach called social emotion optimization algorithm(SEOA) is proposed in this paper to optimize the linked weights and thresholds of BPNN. Each individual in SEOA represents a BPNN. The availability of the proposed forecasting models is proved with the actual traffic flow data of the 2 nd Ring Road of Beijing. Experiment of results show that the forecasting accuracy of SEOA is improved obviously as compared with the accuracy of particle swarm optimization back-propagation(PSOBP) and simulated annealing particle swarm optimization back-propagation(SAPSOBP) models. Furthermore, since SEOA does not respond to the negative feedback information, Metropolis rule is proposed to give consideration to both positive and negative feedback information and diversify the adjustment methods. The modified BPNN model, in comparison with social emotion optimization back-propagation(SEOBP) model, is more advantageous to search the global optimal solution. The accuracy of Metropolis rule social emotion optimization back-propagation(MRSEOBP) model is improved about 19.54% as compared with that of SEOBP model in predicting the dramatically changing data.

关键词： urban traffic short-term traffic flow forecasting social emotion optimization algorithm(SEOA) back-propagation neural network(BPNN) Metropolis rule

Substation rotational object detection based on multi-scale feature fusion and refinement

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Energy and AI 2023年第4期14卷 490-499页

作者： Bin Li Yalin Li xinshan Zhu Luyao Qu Shuai Wang Yangyang Tian Dan Xu The Key Laboratory of Smart Grid of Ministry of Education Tianjin UniversityTianjin 300072China State Grid Henan Electric Power Research Institute Zhengzhou 450000China XJ Group Corporation Xuchang 461000China

In modern energy systems,substations are the core of electricity transmission and ***,similar appearance and small size pose significant challenges for automatic identification of electrical *** address these issues,we collect and annotate the substation rotated device dataset(SRDD).Further,feature fusion and feature refinement network(F3RNet)are constructed based on the classic structure pattern of *** the similar appearance of electrical devices,the deconvolution fusion module(DFM)is designed to enhance the expression of feature *** balanced feature pyramid(BFP)is embedded to aggregate the global *** feature refinement is constructed to adjust the original feature maps by considering the feature alignment between the anchors and *** can generate more accurate feature *** address the problem of sample imbalance between electrical devices,the gradient harmonized mechanism(GHM)loss is utilized to adjust the weight of each *** ablation experiments are conducted on the SRDD dataset.F3RNet achieves the best detection performance compared with classical object detection ***,it is verified that the features from global feature maps can effectively recognize the similar and small devices.

关键词： Substation Rotated device Object detection Feature fusion Feature refinement

基于CT灌注成像的低灌注和缺血半暗带指数用于急性取栓患者的病因诊断

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中华老年心脑血管病杂志 2024年第2期26卷 179-183页

作者：吴新山鲁潇慧于金萍贾向军艾克拜尔·加马力孟根才次克巴音郭楞蒙古自治州人民医院神经内科 841000 巴音郭楞蒙古自治州人民医院影像科 841000 巴音郭楞蒙古自治州人民医院疼痛科 841000

目的基于CT灌注成像的相关参数灌注显像不匹配(Mismatch)比率及低灌注指数(HIR)用于预测颅内动脉粥样硬化性狭窄(ICAS)相关的急性颅内大血管闭塞。方法选择2019年2月至2020年12月巴音郭楞蒙古自治州人民医院神经内科收治的急性颅内大血... 详细信息

目的基于CT灌注成像的相关参数灌注显像不匹配(Mismatch)比率及低灌注指数(HIR)用于预测颅内动脉粥样硬化性狭窄(ICAS)相关的急性颅内大血管闭塞。方法选择2019年2月至2020年12月巴音郭楞蒙古自治州人民医院神经内科收治的急性颅内大血管闭塞行急诊取栓患者82例,根据发病机制分为ICAS相关大血管闭塞(ICAS-LVO)组65例和心源性栓塞组17例。使用ROC曲线分析CT灌注成像参数的预测价值。结果与心源性栓塞组比较,ICAS-LVO组男性、体质量指数、三酰甘油、病程进展性加重、发病至手术时间、缺血半暗带、Mismatch比率明显升高,心房颤动、B型钠尿肽、高密度脂蛋白、梗死体积、HIR明显降低,差异有统计学意义(P<0.05,P<0.01)。ROC曲线分析显示,HIR和Mismatch比率对ICAS-LVO病因具有良好的预测价值,其中HIR的最佳截断值为0.26,曲线下面积为0.74,特异性为0.88,敏感性为0.54;Mismatch比率的最佳截断值为3.84,曲线下面积为0.84,特异性为0.75,敏感性为0.90。广义线性模型显示,HIR与脑血容量指数对预后能力无显著差异(P=0.175)。结论HIR及Mismatch比率有助于及早明确发病机制,更准确地制定手术策略,从而更大程度地减少医源性损伤,提高有效开通率,降低致残率和病死率,并改善临床功能预后。

关键词：颅内动脉硬化脑血管障碍球囊取栓术 CT灌注成像低灌注指数