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The combined effect of bromadiolone and ivermectin (iBr) in controlling both rodents and their fleas

Integrative Zoology 2024年第1期19卷 156-164页

作者： Ming LIU xinrong wan Wei LIU Xingan MA Zhibin ZHANG State Key Laboratory of Integrated Pest Management Institute of ZoologyChinese Academy of SciencesBeijingChina CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijingChina Inner Mongolia Minzu University TongliaoInner MongoliaChina International Society of Zoological Sciences BeijingChina

Rodent pests not only cause severe agricultural loss but also spread zoonotic pathogens to human ***-agulant rodenticides are widely used to decrease the population densities of rodents but often lead to the spillover of ectoparasites becausefleas and ticks may gather on surviving ***,it is necessary to killfleas and ticks before culling rodents to minimize the risk of pathogen *** this study,we used a mixture of ivermectin(an antiparasitic drug)and bromadiolone(an anticoagulant rodenticide)to control both rodent andflea/tick *** found that in a laboratory test,0.01%ivermectin bait was not lethal for greater long-tailed hamsters after 7 days of treatment,while 0.1%ivermectin bait was lethal for approximately 33%of treated *** afield test,bait containing 0.001%,0.005%,0.01%,and 0.05%ivermectin decreased the number offleas per vole of Brandt’s voles to 0.42,0.22,0.12,and 0.2,respectively,compared with 0.77 in the control group,indicating that 0.01%ivermectin bait performed best in *** another laboratory test,bait containing a 0.01%ivermectin and 0.005%bromadiolone mixture caused the death of all voles within 6–14 days after the intake of the *** thefield test,the bait containing 0.01%ivermectin and 0.005%bromadiolone reduced the average number offleas per vole to 0.35,which was significantly lower than the 0.77 of the control *** results indicate that a 0.01%ivermectin and 0.005%bromadiolone mixture could be used to control both rodents andfleas to minimize the spillover risk of disease transmission when using traditional rodenticides.

关键词： bromadiolone flea iBr ivermectin rodent synergistic control

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用主流价值导向驾驭算法的内在动因、本质透视与实践路径

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马克思主义研究 2024年第5期 135-144页

作者：万欣荣中山大学马克思主义学院广东省习近平新时代中国特色社会主义思想研究中心广东广州510275

“用主流价值导向驾驭算法”是社会主义核心价值观引导算法健康有序发展的权力治理模式。依循“标注化采集-倍速化生产-个性化分发-差异化接收-支配化反馈”的信息传播轨迹,算法对主流舆论产生负向冲击,并呈现多维风险样态。究其本质,... 详细信息

“用主流价值导向驾驭算法”是社会主义核心价值观引导算法健康有序发展的权力治理模式。依循“标注化采集-倍速化生产-个性化分发-差异化接收-支配化反馈”的信息传播轨迹,算法对主流舆论产生负向冲击,并呈现多维风险样态。究其本质,“用主流价值导向驾驭算法”呈现出以领导权、管理权、话语权为核心的三重权力意图。其实践路径为:增进理性自觉的算法认知,规避主流舆论安全风险;培植精神自醒的算法情感,筑牢主流舆论认同根基;强化行业自律的算法伦理,完善主流奥论规制体系;形塑文明自信的算法价值观,提升主流奥论引领能力。

关键词：主流价值导向社会主义核心价值观驾驭算法网络意识形态

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“算法中立”的命题证伪——基于历史唯物主义的视角

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思想理论教育 2024年第6期 87-93页

作者：万欣荣中山大学马克思主义学院广东广州510275

作为第四次科技革命孕育的经典命题,“算法中立”通常成为资本主义国家科技巨头利用技术手段实施不当竞争和市场垄断却免于法律担责的抗辩事由。基于历史唯物主义的视角,在追溯算法的机器本体及其“中立”争议的基础上,通过剖析算法的... 详细信息

作为第四次科技革命孕育的经典命题,“算法中立”通常成为资本主义国家科技巨头利用技术手段实施不当竞争和市场垄断却免于法律担责的抗辩事由。基于历史唯物主义的视角,在追溯算法的机器本体及其“中立”争议的基础上,通过剖析算法的资本主义应用及其所引起的价值冲击,以实现对“算法中立”的命题证伪。究其根源,以获取剩余价值为根本目的的资本主义制度为算法打上了深刻的资本烙印,使其难以在应用过程中摆脱代码精英的利益偏好,成为纯粹客观中立的理性存在。只有从“以人为本”的价值立场出发,规避资本裹挟下“算法异化”的风险,才能真正实现数字文明时代的“算法向善”。

关键词：算法算法中立历史唯物主义

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驯服算法:算法语境下的网络主流意识形态建设风险与应对策略

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昆明理工大学学报（社会科学版） 2024年第3期24卷 37-45页

作者：万欣荣刘良健田淼中山大学马克思主义学院广东广州510275 南开大学马克思主义学院天津300350

算法作为新质生产力的代表技术,潜藏着技术开发者、使用者的价值取向和利益诉求,具有鲜明的意识形态属性。算法与网络主流意识形态建设存在双向互动关系:算法为网络主流意识形态建设形塑发展场域、精准内容生产和提供评价反馈;网络主流... 详细信息

算法作为新质生产力的代表技术,潜藏着技术开发者、使用者的价值取向和利益诉求,具有鲜明的意识形态属性。算法与网络主流意识形态建设存在双向互动关系:算法为网络主流意识形态建设形塑发展场域、精准内容生产和提供评价反馈;网络主流意识形态建设又反过来规正技术发展、约束内容表达和监督实时评价。算法的资本主义应用造成了干扰主流意识形态呈现、弱化主流意识形态认同、离散主流意识形态权威等风险样态。坚持主体驾驭算法、规范算法内容、优化算法技术三维举措同向发力、协同推进,可以使网络主流意识形态建设增添人文关怀、打牢现实根基和释放最大增量。

关键词：网络主流意识形态意识形态话语权网络安全算法推荐工具理性

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镇肝清心熄风汤治疗特应性皮炎临床观察

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河北中医 2024年第4期46卷 570-573页

作者：李孜怡林欢儿万欣荣杜亚娜北京中医药大学深圳医院皮肤科广东深圳518116

目的观察镇肝清心熄风汤治疗特应性皮炎临床疗效。方法选取2019年8月至2021年8月收治的64例特应性皮炎患者为研究对象,按照随机数字表法分为2组,对照组32例予西医常规治疗,治疗组32例在对照组基础上联合镇肝清心熄风汤治疗。2组均治疗2... 详细信息

目的观察镇肝清心熄风汤治疗特应性皮炎临床疗效。方法选取2019年8月至2021年8月收治的64例特应性皮炎患者为研究对象,按照随机数字表法分为2组,对照组32例予西医常规治疗,治疗组32例在对照组基础上联合镇肝清心熄风汤治疗。2组均治疗2个月后统计疗效,比较2组治疗前后病情严重程度[采用特应性皮炎评分(SCORAD)、皮肤病生活质量指数(DLQI)和湿疹面积及严重程度指数(EASI)进行评价]、免疫功能指标[包括辅助性T淋巴细胞1(Th1)、Th2、Th17及调节性T淋巴细胞(Treg)]及炎症相关指标[包括白细胞介素10(IL-10)、转化生长因子β(TGF-β)、IL-17、IL-22及IL-23]水平变化情况。结果治疗组总有效率93.8%(30/32),对照组总有效率75.0%(24/32),治疗组总有效率高于对照组(P<0.05)。与本组治疗前比较,2组治疗后SCORAD评分、EASI评分及DLQI评分均降低(P<0.05),且治疗组治疗后SCORAD评分、EASI评分及DLQI评分均低于对照组(P<0.05)。与本组治疗前比较,2组治疗后免疫功能指标Th1及Treg水平均升高(P<0.05),Th2及Th17水平均降低(P<0.05),且治疗组治疗后Th1及Treg水平均高于对照组(P<0.05),Th2及Th17水平均低于对照组(P<0.05)。与本组治疗前比较,2组治疗后炎症相关指标IL-10、TGF-β、IL-22及IL-23水平均降低(P<0.05),且治疗组治疗后IL-10、TGF-β、IL-22及IL-23水平均低于对照组(P<0.05)。结论镇肝清心熄风汤治疗特应性皮炎效果良好,可有效促进皮损修复,缩小皮损面积,减轻皮损程度,提高生活质量,其作用机制可能与改善机体免疫环境,恢复免疫平衡,控制炎症因子的异常分泌,抑制炎症反应有关。

关键词：皮炎,特应性平肝熄风清心泻火中药疗法

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Sheep grazing causes shift in sex ratio and cohort structure of Brandt’s vole:Implication of their adaptation to food shortage

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Integrative Zoology 2016年第1期11卷 76-84页

作者： Guoliang LI Xianglei HOU xinrong wan Zhibin ZHANG State Key Laboratory of Integrated Pest Management Institute of ZoologyChinese Academy of SciencesBeijingChina College of Life Science University of Chinese Academy of SciencesBeijingChina

Livestock grazing has been demonstrated to affect the population abundance of small rodents in grasslands,but the causative mechanism of grazing on demographic parameters,particularly the age structure and sex ratio,is rarely *** this study,we examined the effects of sheep grazing on the cohort structure and sex ratio of Brandt’s vole(Lasiopodomys brandtii)in Inner Mongolia of China by using large manipulative experimental enclosures during *** results indicated that sheep grazing significantly decreased the proportion of the spring-born cohort,but increased the proportion of the summer-born *** increased the proportion of males in both spring and summer *** addition,we found a negative relation between population density and the proportion of the overwinter *** results suggest that a shift in the cohort structure and the sex ratio may be an important strategy for small rodents to adapt to changes in food resources resulting from livestock grazing.

关键词： age structure food resources population demography population regulation sex ratio

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Restricted dispersal determines fine-scale spatial genetic structure of Mongolian gerbils

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Current Zoology 2017年第6期63卷 687-691页

作者： Guiming wanG Wei LIU Yanni wanG xinrong wan Wenqin ZHONG Department of Wildlife Fisheries and Aquaculture Mississippi State University Mail Stop 9690 Mississippi State MS 39762 USA Institute of Zoology Chinese Academy of Sciences State Key Laboratory of Integrated Management of Pest Insects and Rodents 1 Beichen West Road Chaoyang District Beijing 100101 China University of Chinese Academy of Sciences Beijing 100190 China College of Chemistry and Life Sciences Zhejiang Normal University 688 Yingbin Road Jinhua Zhejiang 321004 China

Restricted gene flow may cause positive spatial genetic autocorrelation of animal populations at fine spatial scales. The Mongolian gerbil is a territorial, social rodent. Territoriality may create social fences to restrict dispersal or gene flow of Mongolian gerbils to a short distance. Restricted dispersal may differentiate fine-scale spatial genetic structure of populations with increasing distances (i.e., isolation by distance [IBD]). Competition for mates and inbreeding avoidance may result in equal dispersal propensity and subsequently similar spatial genetic autocorrelation between males and females of monogamous gerbils. We genotyped 327 gerbils, live captured from 26 burrow systems on a 9-ha plot in northcentral Inner Mongolia, China, using seven microsatellite loci. Spatial genetic autocorrelation was positive within 80 m and became negative from 80 m to 200 m, suggesting restricted gene flow. Inter-group genetic and geographic distances were related positively, supporting the IBD model. Live trapping data demonstrated equal dispersal propensities of male and female gerbils. Restricted dispersal and social organization may determine fine-scale spatial population genetic structure of social rodents.

关键词： Meriones unguiculatus dispersal isolation by distance microsatellite analysis social rodents spatial genetic autocorrelation

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Large manipulative experiments reveal complex effects of food supplementation on population dynamics of Brandt's voles

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Science China(Life Sciences) 2017年第8期60卷 911-920页

作者： Baofa Yin Guoliang Li xinrong wan Guozhen Shang wanhong Wei Zhibin Zhang State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of Sciences College of Bioscience and Biotechnology Yangzhou University

Although food supplementation is well known to increase population density,there is still debate on the causative effects of food supplementation on reproduction,survival,and *** manipulative experiments,which exclude any confounding effects of dispersal and predation,are essential for clarifying the *** this study,we investigated the effects of food supplementation on Brandt's vole population dynamics and plant community in eight large enclosures(0.48 ha each) from2010 to *** supplementation showed significant positive effects on population density due to increases in recruitment;however,it showed a complex effect on survival of voles:positive in non-breeding seasons,but negative in breeding *** addition,food supplementation increased the quality of plants(as reflected by increased crude protein content),but decreased the quantity of less preferred plants in experimental ***,food seems to have direct positive effects on small rodents through improvement of food supply and indirect negative effects through food-induced density-dependent effects,and may have long-term effects on rodents through altering plant community composition and abundance.

关键词：食物供应种群动态田鼠实验操纵非繁殖季节植物群落密度依赖效应

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网络舆情泛道德化:伴生危害、形成逻辑与治理策略

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山东师范大学学报（社会科学版） 2023年第1期68卷 21-29页

作者：陈珂万欣荣中山大学马克思主义学院广东广州510275

在互联网加持的快信息时代,重大突发事件容易引发网络舆情的泛道德化,给国家治理带来危害,包括加剧公共治理难度、弱化公众理性思考力、导致舆论监督失焦等。泛道德化是思维、环境、机制等多方面要素在网络舆论场中互相影响的产物,其表... 详细信息

在互联网加持的快信息时代,重大突发事件容易引发网络舆情的泛道德化,给国家治理带来危害,包括加剧公共治理难度、弱化公众理性思考力、导致舆论监督失焦等。泛道德化是思维、环境、机制等多方面要素在网络舆论场中互相影响的产物,其表征为当事人身份标签化、叙述表达偏见化、评价标尺非理性化、情绪抒发负面化等。公众心态受失德事件引发、媒介推波助澜而走向群体“极化”,技术机制的缺陷造成网络舆论的弱把关,最终形成网络舆情的泛道德化现象。应建立由政府主导、纳入公众参与、增强多元协同的治理机制,包括:增强治理主体多元化,寻求泛道德化舆情治理的价值共识;搭建多元主体德育交流平台,建立泛道德化舆情协同治理机制;构建智能化道德引领平台,合理开拓泛道德化舆情治理中的技术赋能。

关键词：网络舆情泛道德化舆情治理治理机制

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Density-induced social stress alters oxytocin and vasopressin activities in the brain of a small rodent species

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Integrative Zoology 2021年第2期16卷 149-159页

作者： Shuli HUANG Guoliang LI Yongliang PAN Mingjing SONG Jidong ZHAO xinrong wan Charles JKREBS Zuoxin wanG Wenxuan HAN Zhibin ZHANG State Key Laboratory of Integrated Pest Management Institute of ZoologyChinese Academy of SciencesBeijingChina CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijingChina School of Medicine Huzhou UniversityHuzhouChina Key Laboratory of Human Disease Comparative Medicine National Health Commission of China(NHC)Beijing Engineering Research Center for Experimental Animal Models of Human DiseasesInstitute of Laboratory Animal SciencePeking Union Medicine CollegeChinese Academy of Medical ScienceBeijingChina Department of Zoology University of British ColumbiaVancouverBritish ColumbiaCanada Department of Psychology and Program in Neuroscience Florida State UniversityTallahasseeFloridaUSA College of Resources and Environmental Sciences China Agricultural UniversityBeijingChina

It is known that social stress could alter oxytocin(OT)and arginine-vasopressin(AVP)expression in specific regions of brains which regulate the aggressive behavior of small rodents,but the effects of density-induced social stress are still ***’s voles(Lasiopodomys brandtii)are small herbivores in the grassland of China,but the underlying neurological mechanism of population regulation is still *** tested the effects of housing density of Brandt’s voles on OT/AVP system with physical contact(allowing aggression)and without physical contact(not allowing aggression)under laboratory ***,we tested the effects of paired-aggression(no density effect)of Brandt’s voles on OT/AVP system under laboratory *** hypothesized that high density would increase aggression among animals which would then increase AVP but reduce OT in brains of *** results showed that high housing density induced more aggressive *** found high-densityinduced social stress(with or without physical contact)and direct aggression significantly increased expression of mRNA and protein of AVP and its receptor,but decreased expression of mRNA and protein of OT and its receptor in specific brain regions of *** results suggest that density-dependent change of OT/AVP systems may play a significant role in the population regulation of small rodents by altering density-dependent aggressive behavior.

关键词： aggression behavior density-dependent stress oxytocin(OT) social stress vasopressin(AVP)

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