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Cortical Deficits are Correlated with Impaired Stereopsis in Patients with Strabismus

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Neuroscience Bulletin 2023年第7期39卷 1039-1049页

作者： Sida Xi Yulian Zhou Jing Yao xinpei Ye Peng Zhang Wen Wen Chen Zhao Department of Ophthalmology and Visual Science Eye and ENT HospitalShanghai Medical CollegeFudan UniversityShanghai 200031China State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institutes of Brain ScienceFudan UniversityShanghai 200031China Key Laboratory of Myopia Fudan UniversityMinistry of HealthShanghai 200031China Shanghai Key Laboratory of Visual Impairment and Restoration Fudan UniversityShanghai 200031China Department of Radiology Eye and ENT HospitalShanghai Medical CollegeFudan UniversityShanghai 200031China State Key Laboratory of Brain and Cognitive Science Institute of BiophysicsChinese Academy of SciencesBeijing 100101China

In this study,we explored the neural mechanism underlying impaired stereopsis and possible functional plasticity after strabismus *** enrolled 18 stereo-deficient patients with intermittent exotropia before and after surgery,along with 18 healthy *** magnetic resonance imaging data were collected when participants viewed three-dimensional *** with controls,preoperative patients showed hypoactivation in higher-level dorsal(visual and parietal)areas and ventral visual ***-and postoperative activation did not significantly differ in patients overall;patients with improved stereopsis showed stronger postoperative activation than preoperative activation in the right V3A and left intraparietal *** stereopsis and fusional control were correlated with preoperative hypoactivation,suggesting that cortical deficits along the two streams might reflect impaired stereopsis in intermittent *** correlation between improved stereopsis and activation in the right V3A after surgery indicates that functional plasticity may underlie the improvement of ***,additional postoperative strategies are needed to promote functional plasticity and enhance the recovery of stereopsis.

关键词： Stereopsis Binocular disparity Functional magnetic resonance imaging Strabismus Intermittent exotropia

Arsenic removal from acidic industrial wastewater by ultrasonic activated phosphorus pentasulfide

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Chinese Journal of Chemical Engineering 2023年第8期60卷 46-52页

作者： Bo Yu Guang Fu xinpei Li Libo Zhang Jing Li Hongtao Qu Dongbin Wang Qingfeng Dong Mengmeng Zhang Faculty of Metallurgical and Energy Engineering Kunming University of Science and TechnologyKunming 650093China Kunming Key Laboratory of Special Metallurgy Kunming University of Science and TechnologyKunming 650093China Key Laboratory of Unconventional Metallurgy Ministry of EducationKunming 650093China Yunnan Chihong Zn&Ge Co. LtdQujing 655011China

Arsenic is one of the main harmful elements in industrial *** to remove arsenic has always been one of the research hotspots in academic *** the process of arsenic removal by traditional sulfuration,the use of traditional sulfurizing agent will introduce new metal cations,which will affect the recycling of *** this study,phosphorus pentasulfide (P_(2)S_(5)) was used as sulfurizing agent,which hydrolyzed to produce H_(3)PO_(4) and H_(2)S without introducing new metal *** effect of ultrasound on arsenic removal by P_(2)S_(5) was *** the action of ultrasound,the utilization of P_(2)S_(5) was improved and the reaction time was *** effects of S/As molar ratio and reaction time on arsenic removal rate were investigated under ultrasonic *** enhanced heat and mass transfer so that the arsenic removal rate of 94.5%could be achieved under the conditions of S/As molar ratio of 2.1:1 and reaction time of 20 *** the first 60 min,under the same S/As molar ratio and reaction time,the ultrasonic hydrolysis efficiency of P_(2)S_(5) was *** is because P_(2)S_(5) forms ([(P_(2)S_(4))])^(2+)under the ultrasonic action,and the structure is damaged,which is easier to be *** addition,the precipitation after arsenic removal was characterized and analyzed by X-ray diffraction,scanning electron microscope-energy dispersive spectrometer,X-ray fluorescence spectrometer and X-ray photoelectron *** research avoids the introduction of metal cations in the arsenic removal process,and shortens the reaction time.

关键词： Arsenic removal Mass transfer Precipitation Waste water Ultrasound

Near-Infrared Light-Activatable Melanized Paclitaxel Nano-Self-Assemblies for Synergistic Anti-tumor Therapy

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Journal of Analysis and Testing 2023年第3期7卷 204-214页

作者： Qiming Zhu Peizhe Li Qiwen Huang xinpei Ding Nan Wang Weijun Yao Maozhong Miao Zhijun Zhang Key Laboratory of Surface&Interface Science of Polymer Materials of Zhejiang Province School of Chemistry and Chemical EngineeringZhejiang Sci-Tech UniversityHangzhou 310018China Shaoxing Keqiao Research Institute of Zhejiang Sci-Tech University Shaoxing 312000China Shengzhou Innovation Research Institute of Zhejiang Sci-Tech University Shengzhou 312400China

Building self-assembly nanostructures is an important way to overcome the limitations of paclitaxel in tumor ***,this strategy is also faced with challenges,such as difficulties in efficient release and the potential for drug ***,we developed a near-infrared light-activatable melanized paclitaxel self-assembly nanoparticles for synergistic anti-tumor *** this strategy,paclitaxel dimer prodrugs were synthesized and paclitaxel nanoparticles were obtained through ***,the paclitaxel dimer nanoparticles were capped with polydopamine(PDA,melanoidin)and human serum albumin(HSA).The disulfide bonds in paclitaxel dimeric prodrug specifically respond to high concentrations of glutathione(GSH)and reactive oxygen species(ROS)in tumor *** enhances the biocompatibility of the drug molecules and imparts near-infrared photothermal conversion capability to the *** the in vitro and in vivo experiments demonstrated that this paclitaxel nanoprodrug exhibited enhanced tumor therapeutic efficacy under near-infrared light irradiation.

关键词： Paclitaxel nano-self-assemblies Synergistic anti-tumor therapy Photothermal eff ect Melanoidins Nearinfrared light-activatable

Chlorination of water containing bromide and formation of the bromine－substituted trihalomethanes

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Journal of Environmental Sciences 1995年第4期7卷 443-448页

作者： Li Junwen , Yu Zuobin , Chao Fuhuan , Cai xinpei(Institute of Hygiene and Environmental Medicine, Tianjin 300050 , China) Inst of Hygiene & Envmtl Medicine Tianjin 300050 China

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Ｃｈｌｏｒｉｎａｔｉｏｎｏｆｗａｔｅｒｃｏｎｔａｉｎｉｎｇｂｒｏｍｉｄｅａｎｄｆｏｒｍａｔｉｏｎｏｆｔｈｅｂｒｏｍｉｎｅ－ｓｕｂｓｔｉｔｕｔｅｄｔｒｉｈａｌｏｍｅｔｈａｎｅｓＬｉＪｕｎｗｅｎ，ＹｕＺｕｏｂｉｎ，ＣｈａｏＦｕｈｕａｎ，ＣａｉＸｉｎｐｅｉ...

关键词： chlorination bromination bromine - substituted THMs.

NIR Light-Promoted Whole-Cell Catalysis Based on a Light-Harvesting Blackbody Bioreactor

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Journal of Analysis and Testing 2023年第3期7卷 237-244页

作者： Jinhui Gu Qisi Li Mengting Cao Xiaojia Zhang xinpei Ding Haiyan Chen Nan Wang Zhijun Zhang Key Laboratory of Surface and Interface Science of Polymer Materials of Zhejiang Province School of Chemistry and Chemical EngineeringZhejiang Sci-Tech UniversityHangzhou 310018China Shaoxing Keqiao Research Institute of Zhejiang Sci-Tech University Shaoxing 312000China Shengzhou Innovation Research Institute of Zhejiang Sci-Tech University Shengzhou 312400China

Whole-cell catalysis,which utilizes enzymes expressed in whole organism(*** and fungi)as the catalyst,is a specific mode of *** with pure enzyme catalysis,the catalysis with whole-cell catalysts is more ***,in the process of whole-cell catalysis,heat treatment is often necessary due to the high optimum temperature of the *** enable efficient industrial application of whole-cell catalysis,an environmental friendly heating approach is highly *** by the light harvest by blackbody materials,in this paper,we introduced a photothermal approach for harnessing the photon energy for enhanced whole-cell catalysis.A blackbody porous sponge(BPS)with excellent photothermal conversion efficiency was prepared as a *** coli expressed with a thermophilic enzyme(β-glucosidase)was utilized as a model whole-cell ***,the photothermal properties of the BPS and lightassisted whole-cell catalysis were systematically investigated,demonstrating promising application prospects.

关键词： Whole-cell catalysis Biocatalysis Photothermal eff ect Near-infrared light response Blackbody materials Porous sponge

On the chronological understanding of the homogeneous dielectric barrier discharge

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High Voltage 2023年第6期8卷 1132-1150页

作者： xinpei Lu Zhi Fang Dong Dai Tao Shao Feng Liu Cheng Zhang Dawei Liu Lanlan Nie Chunqi Jiang State Key Laboratory of Advanced Electromagnetic Engineering and Technology School of Electrical and Electronic EngineeringHuazhong University of Science and TechnologyWuhanChina College of Electrical Engineering and Control Science Nanjing Tech TechnologyNanjingChina School of Electric Power South China University of TechnologyGuangzhouChina Institute of Electrical Engineering Chinese Academy of SciencesBeijingChina Frank Reidy Research Center for Bioelectrics Old Dominion UniversityNorfolkVirginiaUSA Department of Electrical and Computer Engineering Old Dominion UniversityNorfolkVirginiaUSA

Dielectric barrier discharges(DBD)are widely utilised non‐equilibrium atmospheric pressure plasmas with a diverse range of applications,such as material processing,surface treatment,light sources,pollution control,and *** the course of several decades,extensive research has been dedicated to the generation of homogeneous DBD(H‐DBD),focussing on understanding the transition from H‐DBD to filamentary DBD and exploring strategies to create and sustain H‐*** paper first discusses the in-fluence of various parameters on DBD,including gas flow,dielectric material,surface conductivity,and mesh ***,a chronological literature review is presented,highlighting the development of H‐DBD and the associated understanding of its un-derlying *** encompasses the generation of H‐DBD in helium,nitrogen,and ***,the paper provides a brief overview of multiple‐current‐pulse(MCP)behaviours in H‐*** objective of this article is to provide a chronological un-derstanding of homogeneous dielectric barrier discharge(DBD).This understanding will aid in the design of new experiments aimed at better comprehending the mechanisms behind H‐DBD generation and ultimately assist in achieving large‐volume H‐DBD in an air environment.

关键词： dielectric barrier pollution

Trihalomethanes adsorption on activated carbon fiber

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Journal of Environmental Sciences 1996年第2期8卷 167-172页

作者： Li Junwen Yu Zuobin Gao Ming Cai xinpei Chao Fuhuan (Institute of Hygiene and Environmental Medicine, TianJin 300050, China) Inst. of Hyg./Environmental Medicine Tianjin 300050 China

The mechanism of activated carbon fiber (ACF) adsorption trihalomethanes (THMs) was studied. It was found that ACF adsorption THMs was exothermic, the physico-adsorption principally, but not a complete monolayer adsorption. The adsorptive capacities of ACF increased as the four species of THMs became more hydrophobic, and as the chlorine atoms in CHCls were substituted by more bromine atoms. The result of fixed-bed reactor adsorption was fitted to that of isotherm experiments.

关键词： trihalomethanes adsorption ACF.

A novel flexible plasma array for large-area uniform treatment of an irregular surface

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Plasma Science and Technology 2022年第3期24卷 130-137页

作者： Baowang LIU Fei QI Dejiang ZHOU Lanlan NIE Yubin XIAN xinpei LU State Key Laboratory of Advanced Electromagnetic Engineering and Technology Huazhong University of Science and TechnologyWuhan 430074People's Republic

In this work,we demonstrate a flexible multi-pin plasma generator with movable electrodes,which can change the shape of the electrode array freely,and then provide a large-area uniform plasma for the treatment of surfaces of different *** characteristics including U-I waveforms and discharge images and sterilization performance under three different electrode configurations(flat-flat,flat-curve,curve-curve)are *** similar results are acquired between the flat-flat configuration and the curve-curve configuration,which is much better than that under flat-curve *** flexible multi-pin plasma generator offers a simple method to treat different irregularly shaped surfaces uniformly with a single ***,this device provides a foundation for developing a self-adaption large-scale uniform plasma generator by further introducing automatic adjustment of the position of every electrode driven by motors with discharge current feedback in the following *** it will promote the applications of atmospheric-pressure cold plasmas significantly.

关键词： flexible multi-pin electrode large-area uniform plasma sterilization

Quantifying competitive advantages of mutant strains in a population involving importation and mass vaccination rollout

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Infectious Disease Modelling 2021年第1期6卷 988-996页

作者： Fan Xia xinpei Yang Robert A.Cheke Yanni Xiao School of Mathematics and Statistics Xi'an Jiaotong UniversityXi'an710049China School of Mathematics and Statistics Shaanxi Normal UniversityXi'an710119China Natural Resources Institute University of Greenwich at MedwayCentral AvenueChatham MaritimeKentME44BUK

The SARS-CoV-2 Delta variant,known as B.1.617.2 and first identified in India,is becoming a dominant strain in many countries due to its extreme *** and quantifying the transmissibility and competitive advantage of the Delta variant is of major significance for countries around the world so that appropriate measures to mitigate and even eliminate the epidemic can be *** at such problems,we proposed a method to model the invasion process of a novel strain and estimate the competitive advantage of the invading strain over the local *** applied this method to study the invasion and spread of the Delta variant into *** have estimated the basic reproduction number of the Delta variant as being 49%higher than that of the Alpha variant(CI:45-52%),assuming a mean generation interval of 5 days with a standard deviation of 3 *** the period 11 April to 17 May 2021,the effective reproduction number of the Delta variant was 65%higher than that of the Alpha variant in England(CI:61-70%).Our results show that the Delta variant has a significantly higher transmission capacity than other strains,which explains the rebound of the epidemic in many countries,even in those with relatively high vaccination coverages.

关键词： COVID-19 SARS-CoV-2 Delta variant Competitive advantage Reproduction number