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Long-term and combined effects of N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide and fumaric acid on methane production,rumen fermentation, and lactation performance in dairy goats

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Journal of Animal Science and Biotechnology 2022年第3期13卷 852-863页

作者： Zongjun Li xinjian lei Xiaoxu Chen Qingyan Yin Jing Shen Junhu Yao College of Animal Science and Technology Northwest A&F UniversityYangling 712100ShaanxiChina

Background:In recent years,nitrooxy compounds have been identified as promising inhibitors of methanogenesis in ***,when animals receive a nitrooxy compound,a high portion of the spared hydrogen is eructated as gas,which partly offsets the energy savings of *** objective of the present study was to evaluate the long-term and combined effects of supplementation with N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide(NPD),a methanogenesis inhibitor,and fumaric acid(FUM),a hydrogen sink,on enteric CH4production,rumen fermentation,bacterial populations,apparent nutrient digestibility,and lactation performance of dairy ***:Twenty-four primiparous dairy goats were used in a randomized complete block design with a 2×2factorial arrangement of treatments:supplementation without or with FUM(32 g/d)or NPD(0.5 g/d).All samples were collected every 3 weeks during a 12-week feeding *** FUM and NPD supplementation persistently inhibited CH4yield(L/kg DMI,by 18.8%and 18.1%,respectively)without negative influence on DMI or apparent nutrient *** supplemented in combination,no additive CH4suppression was *** showed greater responses in increasing the molar proportion of propionate when supplemented with NPD than supplemented alone(by 10.2%vs.4.4%).The rumen microbiota structure in the animals receiving FUM was different from that of the other animals,particularly changed the structure of phylum *** milk production and serum total antioxidant capacity were improved by NPD,but the contents of milk fat and protein were decreased,probably due to the bioactivity of absorbed NPD on body ***:Supplementing NPD and FUM in combination is a promising way to persistently inhibit CH4emissions with a higher rumen propionate ***,the side effects of this nitrooxy compound on animals and its residues in animal products need further evaluation before it can be used as an animal feed additiv

关键词： Bacterial populations Dairy goat Fumaric acid Lactation performance Methane emissions N-[2-(nitrooxy)ethyl]-3-pyridinecarboxamide Rumen fermentation

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Active dry yeast supplementation benefits ruminal fermentation,bacterial community,blood immunoglobulins,and growth performance in young dairy goats,but not for intermittent supplementation

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Animal Nutrition 2023年第2期13卷 289-301页

作者： Jun Zhang Yuntian Yang xinjian lei Yannan Wang Yanhua Li Zhiqiang Yang Junhu Yao College of Animal Science and Technology Northwest A&F UniversityYangling 712100ShaanxiChina Fuping County Animal Husbandry Development Center Fuping 711700ShaanxiChina Shandong Institute of Feed Quality Inspection Jinan 250010ShandongChina

This study evaluated the effects of active dry yeast(ADY)supplementation and supplementation stra-tegies on ruminal fermentation,bacterial community,blood metabolites,and growth performance in young dairy *** young female Guanzhong dairy goats of similar age(4.00±0.50 months)and BW(19.65±0.41 kg)were randomly divided into 3 groups(n=20):(1)basal diet group(CON);(2)basal diet continuously supplemented with 3.0 g/goat per day commercial ADY(a proprietary strain of Saccharomyces cerevisiae with 5.0×10^(9)cfu/g)group(CSY);(3)basal diet with intermittently supple-mented ADY group(ISY;5 d supplementation with ADY at 4.5 g/goat per day following 5 d of no sup-plementation).The experiment lasted 67 d with the first 7 d as an adaptive *** fluid and blood samples were collected *** were analyzed using the MIXED procedure combined with the SLICE option in *** orthogonal contrasts of ADY *** and CSY *** were also *** the experimental period,ADY supplementation resulted in greater DMI(P=0.03),ruminal ac-etate proportion(P<0.01)and acetylesterase activity(P=0.01),and blood contents of glucose(P=0.01)and IgM(P=0.02)and tended to have greater ADG(P=0.05)and paunch girth(P=0.06)than the CON,despite the propionate proportion(P=0.03)and contents of total protein(P=0.04)and IgA(P=0.03)being *** lower ruminal NH_(3)-N(P<0.01)and blood urea nitrogen(P=0.07)contents indicated greater nitrogen utilization with ADY *** supplementation showed persistent effects after it was stopped because the BW at 12 months of age(P=0.03)and birth weight of lambs(P=0.02)were greater than the ***,the ISY did not show those benefits and had significantly lower relative abundances of fiber-degrading related bacteria than the *** conclusion,ADY supplementa-tion,especially continuously supplemented,may enhance ADG and ADG:DMI ratio by improving DMI,ruminal cellulolytic bacteria abundance and enzyme activity,nitrogen utilizat

关键词： Active dry yeast Bacterial community Dairy goat Growth performance Rumen microbiota Saccharomyces cerevisiae

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Dietary saccharin sodium supplementation improves the production performance of dairy goats without residue in milk in summer

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Animal Nutrition 2024年第3期18卷 166-176页

作者： Xiongfei Zhang Jirong Lv Jingtao Hui Ao Wu Lichao Zhao Linyu Feng Lu Deng Miao Yu Feng Liu Junhu Yao xinjian lei College of Animal Science and Technology Northwest A&F UniversityYanglingShaanxi 712100China Key Laboratory of Livestock Biology Northwest A&F UniversityYanglingShaanxi 712100China Sichuan Provincial Animal Feeding Regulation Center DadHank Biotechnology CorporationChengduSichuan 611130China

The purpose of this study was to investigate the effects of dietary saccharin sodium supplementation on production performance,serum biochemical indicators,and rumen fermentation of dairy goats in *** Guanzhong dairy goats with similar body weight,days in milk,and milk yield were randomly divided into two dietary treatments:(1)CON:basal diet;(2)SS:basal diet+150 mg/kg saccharin sodium on the basis of dry *** experiment lasted 35 d,including 7 d for adaptation and 28 d for dietary treatments,sampling and data *** dairy goat was housed individually in a clean separate pen with ad libitum access to diet and *** goats fed SS diet had increased dry matter intake(DMI;P=0.037),4%fat corrected milk yield(P=0.049),energy corrected milk yield(P=0.037),milk protein yield(P=0.031),and total solids yield(P=0.036).Serum activity of aspartate aminotransferase(P=0.047)and concentrations of 70-kDa heat shock protein(P=0.090),malondialdehyde(P=0.092),and total protein(P=0.057)were lower in goats fed SS diet than those fed CON *** of saccharin sodium tended to increase activity of glutathione peroxidase in serum(P=0.079).The concentrations of rumen total volatile fatty acid(P=0.042)and butyrate(P=0.038)were increased by saccharin sodium *** supplementation of saccharin sodium increased the relative abundance of Lachnobacterium(P=0.022),Pseudoramibacter(P=0.022),Shuttleworthia(P=0.025),and Syntrophococcus(P=0.037),but reduced the relative abundance of Prevotella_1(P=0.037)and Lachnospiraceae_UCG_008(P=0.037)in *** sodium was observed in feces and urine of goats fed diet supplemented with saccharin sodium,but saccharin sodium was undetectable in the milk of goats receiving SS *** conclusion,administration of saccharin sodium was effective in increasing fat and energy corrected milk yield by increasing DMI and improving rumen fermentation and antioxidant capacity of dairy goats in *** addition,s

关键词： Dairy goat Heat stress Production performance Rumen fermentation Rumen microorganisms Saccharin sodium

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Preliminary PET/CT Study of ^(18)F-FDG Uptake in Cervical and Supraclavicular Brown Adipose Tissue

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Chinese Journal of Clinical Oncology 2008年第5期5卷 349-353页

作者： Na Fang Yanli Wang xinjian Cui lei Zeng Lili Ma Xiumei Zhao Wei Zhao Qing Wang Shan Gao Wei Ding Department of PET/CT Municipal Central Hospital of Qingdao Qingdao 266042 Shandong Province China.

OBJECTIVE The clinical use of PET/CT in oncology has led to the realization that 18F-FDG uptake in brown adipose tissue(BAT) can be a common cause of potentially misleading false-positive PET *** goal of this study was to study 18F-FDG uptake in cervical and supraclavicular regions and its characteristics with PET/*** the PET/CT scans obtained at our institutionfrom July 2007 to January 2008 were retrospectively reviewed forincreased 18F-FDG uptake in *** cases in which increased18F-FDG in cervical and supraclavicular regions was not localizedto a so -tissue mass or lymph node or muscle on the CT images,were included in this *** following features were recorded:body weight,body mass index(BMI) and maximal standardizeduptake value(SUVmax).In these selected patients,the BAT uptake in other area of the body was also *** PET/CT scans were obtained in 457 patients(259 males and 198 females).In all of the scans,cervical and supraclavicular BAT uptake was observed in 12 patients(2 males and 10 females) and was typically bilateral,symmetric and *** range of the SUVmax was 3.6～12.82(mean 6.9 ± 2.6).BAT uptake was more common in females than in males,showing a significant difference(P = 0.004).Although 18F-FDG uptake in BAT occurred more o en in underweight patients with low BMI,there was no difference in the body weight(P = 0.607) or BMI(P = 0.491) of these patients with hypermetabolic BAT compared with *** Hypermetabolic BAT uptake can be localized in cervical and supraclavicular regions with it occurring more commonly in females compared to *** of this potential pitfall with PET/CT is important in improving diagnostic interpretation and accurate staging.

关键词： brown adipose tissue, ^18F-EDG PET/CT.

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螺纹的数控铣削加工

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工具技术 2000年第8期34卷 27-29页

作者：雷新建天津中德现代工业技术培训中心 300191

1 引言传统的螺纹加工方法主要为采用螺纹车刀车削螺纹或采用丝锥、板牙手工攻丝及套扣.随着数控加工技术的发展,尤其是三轴联动数控加工系统的出现,使更先进的螺纹加工方式--螺纹的数控铣削得以实现.

关键词：螺纹加工数控铣削螺纹铣刀

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SYNTHESIS AND STRUCTURE OF [Et4N]2[MoCu3S4(S2CNC5H10)3].DMF——A NEW CLUSTER OF Mo-Cu-S SYSTEM

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结构化学 1988年第2期 99-102页

作者： lei xinjian Liu Qiutian Liu HanqinFuzhou Laboratory of Structure Chemistry and Fujian Institute of Researchon the Structure of Matter, Academia Sinica

INTRODUCTION. In recent years, the di-, tri- and tetranuclear mixed metal Mo-Cu-S clusters have been extensively studied with [MoS4]2- core skeleton unchanged So far in the literatures, the ligands involved in the Mo-... 详细信息

关键词： CNC A NEW CLUSTER OF Mo-Cu-S SYSTEM Et4N]2[MoCu3S4 S2CNC5H10)3 SYNTHESIS AND STRUCTURE OF Mo Cu DMF 甲酰胺

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淀粉在反刍动物消化道的消化特性及整体供能方式优化

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动物营养学报 2022年第7期34卷 4099-4107页

作者：任豪雷新建陈鲁豫姚军虎西北农林科技大学动物科技学院杨凌712100

淀粉是高产反刍动物的主要能量来源,生产中常通过提高饲粮淀粉含量来增加饲粮能量浓度,以期提升动物的生产水平。此做法易导致瘤胃酸中毒和大肠酸中毒等代谢性疾病,严重危害动物健康,限制生产潜力的发挥。本文总结了淀粉在瘤胃、小肠和... 详细信息

淀粉是高产反刍动物的主要能量来源,生产中常通过提高饲粮淀粉含量来增加饲粮能量浓度,以期提升动物的生产水平。此做法易导致瘤胃酸中毒和大肠酸中毒等代谢性疾病,严重危害动物健康,限制生产潜力的发挥。本文总结了淀粉在瘤胃、小肠和大肠降解利用的特点,比较淀粉在各消化位点为机体供能的差异,旨在为淀粉能量最大化供应进而充分发挥反刍动物遗传潜力提供理论依据。

关键词：反刍动物淀粉消化位点能量效率

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过瘤胃葡萄糖对围产期奶畜营养调控的研究进展

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畜牧兽医学报 2023年第8期54卷 3173-3182页

作者：吴志立姚军虎雷新建西北农林科技大学动物科技学院杨凌712100

围产期奶畜的干物质采食量明显下降,同时还需要满足妊娠后期胎儿快速生长发育以及泌乳前期乳汁合成分泌的营养需求,导致奶畜能量代谢紊乱。能量代谢紊乱可引发多种代谢性疾病和炎性疾病,对奶畜生产性能和繁殖机能造成重大负面影响。过... 详细信息

围产期奶畜的干物质采食量明显下降,同时还需要满足妊娠后期胎儿快速生长发育以及泌乳前期乳汁合成分泌的营养需求,导致奶畜能量代谢紊乱。能量代谢紊乱可引发多种代谢性疾病和炎性疾病,对奶畜生产性能和繁殖机能造成重大负面影响。过瘤胃葡萄糖(rumen-protected glucose,RPG)在消化过程中受瘤胃影响小,可在小肠部位高效吸收进入血液并提供安全高效的能量来源,以此缓解奶畜在围产期出现的不良反应。本文总结了围产期的生理代谢特点,综述了RPG对围产期能量代谢、产奶量、乳成分、氧化应激、免疫和炎症的影响及其机制,并对RPG生物利用率进行了简要评价,以期为RPG在围产期奶畜营养调控中的研究与应用提供参考。

关键词：过瘤胃葡萄糖围产期奶畜生理代谢营养调控

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不同测定方法及复合酶制剂对玉米有效能值的影响

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中国粮油学报 2015年第3期30卷 122-127,133页

作者：雷新建刘国华汝应俊汪永香唐德富年芳甘肃农业大学动物科学技术学院兰州730070 中国农业科学院饲料研究所北京100081

本试验选用4个不同来源玉米样品为试验材料,采用全收粪法、指示剂法、回肠末端食糜法等3种生物学方法测定玉米表观代谢能、氮校正代谢能和回肠消化能,并评估添加复合酶制剂对玉米有效能值的影响。选取720只21日龄爱拔益加肉仔鸡供试,随... 详细信息

本试验选用4个不同来源玉米样品为试验材料,采用全收粪法、指示剂法、回肠末端食糜法等3种生物学方法测定玉米表观代谢能、氮校正代谢能和回肠消化能,并评估添加复合酶制剂对玉米有效能值的影响。选取720只21日龄爱拔益加肉仔鸡供试,随机分配到15个处理组,每组设8个重复,每个重复6只鸡。分别接受基础饲粮和由50%基础饲粮分别添加50%待测4个玉米样品组成的试验饲粮,以及在上述5个处理组饲粮中分别添加500 mg/kg复合酶制剂A或100 mg/kg复合酶制剂B共组成15个处理饲粮组。结果表明:不同来源玉米样品的理化成分存在较大变异;全收粪法测得玉米代谢能值高于指示剂法,但无显著差异(P>0.05);添加复合酶制剂B提高了玉米4的回肠消化能(P<0.05)。

关键词：玉米肉仔鸡有效能复合酶制剂

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SYNTHESIS AND STRUCTURE OF THE FIRST TUNGSTEN-IRON-SULFUR CUBANE-LIKE CLUSTER [WFe_3S_4(S_2CNC_4H_8)s]·2DMF CONTAINING DITHIOCARBAMATO LIGANDS

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Chinese Journal of Structural Chemistry 1989年第2期8卷 152-155页

作者：雷新建黄致盈等

The title compound (Mr =1236.54) crystallizes in monoclinic space group C2/c with a =12.553(4),b=20.121(6),c=19.659(2)A,β=102.96(2)°,V=4839.1A3, Z = 4 and DC -1.697g/cm3. The structure was solved by direct methods.A full matrix least-squares refinement for 2197 reflections with I>3σ(I) gave final R and Rw of 0.064 and 0.076,respectively. The [WFe3S4] core of the cluster can be considered to be a [WFe3] tetrahedron capped by a sulfur atom on each face to fora a distorted cubane. The 57Fe Mossbauer spectrum indicates that there are two types of Fe atoms of ratio 2:1 in the cluster.

关键词： monoclinic distorted refinement S2CNC4H8)s WFe3S4 FIRST sulfur reactant refined nitro

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