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面向多标签文本分类的深度主题特征提取

模式识别与人工智能 2019年第9期32卷 785-792页

作者：陈文实刘心惠鲁明羽大连海事大学信息科学技术学院

针对单标签特征提取方法不能有效解决多标签文本分类的问题,文中提出融合主题模型(LDA)与长短时记忆网络(LSTM)的双通道深度主题特征提取模型(DTFEM).LDA与LSTM分别作为两个通道,通过LDA为文本的全局特征建模,利用LSTM为文本的局部特征... 详细信息

针对单标签特征提取方法不能有效解决多标签文本分类的问题,文中提出融合主题模型(LDA)与长短时记忆网络(LSTM)的双通道深度主题特征提取模型(DTFEM).LDA与LSTM分别作为两个通道,通过LDA为文本的全局特征建模,利用LSTM为文本的局部特征建模,使模型能同时表达文本的全局特征和局部特征,实现有监督学习与无监督学习的有效结合,得到文本不同层次的特征提取.实验表明,相比文本特征提取模型,文中模型在多标签分类结果上的多项指标均有明显提升.

关键词：多标签文本分类深度主题特征提取主题模型长短时记忆网络

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20世纪50年代以来壮族花婆神话研究综述

文山学院学报 2022年第1期35卷 29-33页

作者：韦新慧陆明鹏中央民族大学中国少数民族语言文学学院北京100081 贵州民族大学东盟人文学院贵州贵阳550025

关于花婆神话是否是姆洛甲神话学界未统一,但从目前的学术研究成果来看,认为花婆神话就是姆洛甲神话是大部分学者所持的观点。相对于壮族的布洛陀神话研究,花婆神话研究较为薄弱。壮族花婆神话研究与我国民间文学的搜集整理几乎是同步进... 详细信息

关于花婆神话是否是姆洛甲神话学界未统一,但从目前的学术研究成果来看,认为花婆神话就是姆洛甲神话是大部分学者所持的观点。相对于壮族的布洛陀神话研究,花婆神话研究较为薄弱。壮族花婆神话研究与我国民间文学的搜集整理几乎是同步进行,从国家层面对壮族民间文学的搜集、抢救、整理从20世纪50年代开始,进展较为缓慢;到20世纪80年代以后,研究进入了迅猛发展的状态,花婆神话同时也被更多的学者关注,其研究成果层出不穷,研究较为深入、角度更为宽广。文章重点从国内对花婆神话研究现状出发,以文献检索为依据,按照研究角度的差异,将学界对壮族花婆神话研究的历史脉络进行梳理。

关键词：壮族花婆神话研究综述

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土壤剖面重金属污染对微生物群落结构的影响

环境科学与技术 2022年第4期45卷 184-191页

作者：张瀚丹刘新会王宇静段林帅董璐北京师范大学环境学院北京100875

为探明重金属污染土壤剖面对微生物群落结构和微生物多样性的影响,该文以重金属污染严重区(焦化园区)作为研究区域,选择了焦化园区上下风向及园区内部共3个土壤剖面,对重金属含量、土壤理化性质以及微生物群落结构进行分析测定。结果表... 详细信息

为探明重金属污染土壤剖面对微生物群落结构和微生物多样性的影响,该文以重金属污染严重区(焦化园区)作为研究区域,选择了焦化园区上下风向及园区内部共3个土壤剖面,对重金属含量、土壤理化性质以及微生物群落结构进行分析测定。结果表明,研究区域中土壤剖面重金属Cr和Zn污染最严重,Cd和Hg污染最小。由于焦化园区重金属含量明显高于周边区域,证明焦化生产对土壤剖面重金属含量产生较大影响。高通量测序结果表明,土壤剖面微生物群落的优势菌种为酸杆菌门,平均含量为27.20%。多样性指数分析结果表明,焦化园区周边微生物多样性随着土壤深度加深而减少。为探究其影响原因,对重金属浓度及土壤理化性质与微生物多样性相关数据进行相关性分析,分析结果可知,重金属和土壤有机质均与微生物多样性有显著相关性,其中重金属Pb是微生物多样性最重要的影响因素。此外,通过冗余分析发现,微生物中酸杆菌门及放线菌门对重金属污染具有较强耐受力。

关键词：重金属微生物群落土壤剖面

A new anti-hypoxia functional agent ——Schizophyllum commune fermented broth and its biochemical mechanisms

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Engineering Sciences 2013年第2期11卷 82-87页

作者： Hao Limin lu Jike Wu Tianyi Ba Jianming Guo Changjiang Qian Ping Yu Jianyong Xing xinhui The Quartermaster Equipment Institute of GLD of CPLA Department of Bioengineering Zhengzhou University High Altitude Medical Research Institute Department of Endocrinology Chinese PLA General Hospital Institute of Hygiene and Environmental Medicine Academy of Military Medical Sciences Department of Chemical Engineering and Technology Tsinghua University

In order to overcome hypoxia induced sickness,a stable source of anti-hypoxia functional agents, Schizophyllum commune fermented broth has been developed in this study. Animal experiments were conducted to examine its anti-hypoxia activities and possible mechanisms involved. The acute hypoxic experiment showed that Schizophyllum commune fermented broth could significantly prolong the survival time of mice. The underlying mechanisms were associated with improved energy metabolism based on a study carried out in rats exposed to a low pressure chamber simulating the low pressure environment of 8 000 m altitude. It was concluded that the Schizophyllum commune fermented broth was an effective anti-hypoxia functional agent and could be greatly bene- ficial to those living and working at high altitudes,such as people who reside in the reconstruction regions of Yushu.

关键词：生化机制抗缺氧发酵液功能剂裂褶菌动物实验高海拔地区可能机制

lumican Inhibits Angiogenesis by Effecting the Invasion of Endothelial Cells

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Lumican Inhibits Angiogenesis by Effecting the Invasion of E...

羟基磷灰石改性烟草秸秆生物炭钝化修复土壤镉、铜污染

中国生理学会基质生物学专业委员会成立大会暨第一次全国基...

作者： xinhui Fang Ling Ma Haiying Ma Xiaomei lu Yunan Jin Lili Du Yanqiu Yu Department of Cardiology The First Affiliated Hospital of China Medical UniversityPeople's Republic of China Department of Pathophysiology China Medical UniversityPeople's Republic of China Department of Pathophysiology China Medical University

Background:lumican,a class Ⅱ small leucine-rich proteoglycans,have been designated key roles in extracellular matrix *** number of evidence shows that lumican,as an important modulator of biological functions,suppresses *** tested its effects on angiogenesis in vitro and vasculogenesis in vivo and roles on the control of biological behavior of human umbilical vein endothelial cells(HUVEC).Materials and methods:Effect of lumican on vascular development in vivo was evaluated by measuring large vessel structure and liver small vessel density both lumican over-expression mice and wild-type *** angiogenesis in vitro by aortic ring assays in *** in proliferation,adhesion,migration by lumican were analyzed in ***:we found lumican suppressed capillary tube formation in aortic ring assays,but there were not dramatical difference in vivo vascular development between lumican overexpressed mice and wildtype *** lumcan inhibited HVUEC invasion and adhesion on 3.5 h time point but not proliferation and ***:Altogether,our results suggest that lumcan inhibits angiogenesis in vitro by effecting endothelial cells *** vivo,a complicated environment inwhere abundant promoters and inhibitors of angiogenesis coexist,effects of lumican can not be observed.

关键词： lumican Vasculogenesis Angiogenesis human umbilical vein endothelial cells

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华北水利水电大学学报（自然科学版） 2023年第3期44卷 94-101页

作者：李海华丁贺王志琛程新惠禹露华北水利水电大学环境与市政工程学院河南郑州450046

以烟草秸秆为材料,在高温限氧条件下制备成生物炭(BC),同时将纳米羟基磷灰石(nHAP)负载到烟草秸秆生物质表面,制成纳米羟基磷灰石改性生物炭(HBC),通过多种表征手段探究了生物炭改性前后官能团的变化,并研究了BC和HBC对土壤中重金属镉... 详细信息

以烟草秸秆为材料,在高温限氧条件下制备成生物炭(BC),同时将纳米羟基磷灰石(nHAP)负载到烟草秸秆生物质表面,制成纳米羟基磷灰石改性生物炭(HBC),通过多种表征手段探究了生物炭改性前后官能团的变化,并研究了BC和HBC对土壤中重金属镉、铜的钝化效果。结果表明,经纳米羟基磷灰石改性的烟草秸秆生物炭,能显著增加其表面磷基、羧基等含氧官能团的数量。将这2种生物炭分别以1%、2%和3%的比例投加到污染土壤中对土壤进行钝化修复,修复后土壤中Cd和Cu有效态含量降低幅度均分别达30%、40%以上,且Cd和Cu有效态含量降低幅度均随生物炭投加量的增加而增加。纳米羟基磷灰石改性烟草秸秆生物炭可以有效钝化土壤中的Cd和Cu,其中对HBC-3%土样的钝化效果最好。本研究结果可为烟草秸秆的高效利用提供新方法,为磷酸盐修复土壤材料的开发提供参考。

关键词：土壤修复羟基磷灰石烟草秸秆镉、铜污染钝化修复

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基于壳聚糖的基因输送系统研究现状

中华糖尿病杂志 2022年第2期14卷 200-204页

作者：吴欣蕙王海娇刘璐薛涛侯文潭程国鹏卢琰郝瑞英刘璇常菁李秋山东大学齐鲁医学院附属省立医院内分泌科济南250021 山东大学附属省立第三医院内分泌科济南250000 中国海洋大学海洋生命学院青岛266100

基因治疗逐渐成为治疗遗传病、自身免疫性疾病和肿瘤等疾病的重要手段。近年来,人们一直致力于开发高效的基因传递载体以克服各种生理和系统性障碍。壳聚糖具有天然抑菌、止血和促进伤口愈合的能力,以及良好的生物相容性和生物降解性,... 详细信息

基因治疗逐渐成为治疗遗传病、自身免疫性疾病和肿瘤等疾病的重要手段。近年来,人们一直致力于开发高效的基因传递载体以克服各种生理和系统性障碍。壳聚糖具有天然抑菌、止血和促进伤口愈合的能力,以及良好的生物相容性和生物降解性,已被用于药物递送系统以及制造与伤口愈合相关的基因传递系统的候选材料,其亦已被用作各类基因载体为各类难治性疾病的治疗提出新方向,比如作为小干扰RNA载体用于癌症的联合治疗,作为微RNA载体促进糖尿病大鼠皮肤创面愈合等。笔者对壳聚糖载体基因治疗在临床应用上的研究进展进行综述。

关键词：壳聚糖基因输送载体研究进展

Recent Progress in Atmospheric Chemistry Research in China: Establishing a Theoretical Framework for the “Air Pollution Complex”

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Advances in Atmospheric Sciences 2023年第8期40卷 1339-1361页

作者： Tong ZHU Mingjin TANG Meng GAO xinhui BI Junji CAO Huizheng CHE Jianmin CHEN Aijun DING Pingqing FU Jian GAO Yang GAO Maofa GE Xinlei GE Zhiwei HAN Hong HE Ru-Jin HUANG Xin HUANG Hong LIAO Cheng LIU Huan LIU Jianguo LIU Shaw Chen LIU Keding lu Qingxin MA Wei NIE Min SHAO Yu SONG Yele SUN Xiao TANG Tao WANG Tijian WANG Weigang WANG Xuemei WANG Zifa WANG Yan YIN Qiang ZHANG Weijun ZHANG Yanlin ZHANG Yunhong ZHANG Yu ZHAO Mei ZHENG Bin ZHU Jiang ZHU Peking University Beijing 100871China Guangzhou Institute of Geochemistry Chinese Academy of SciencesGuangzhou 510640China Hong Kong Baptist University Hong Kong SARChina Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100029China Chinese Academy of Meteorological Sciences Beijing 100081China Fudan University Shanghai 200438China Nanjing University Nanjing 210023China Tianjin University Tianjin 300072China Chinese Research Academy of Environmental Sciences Beijing 100012China Ocean University of China Qingdao 266100China Institute of Chemistry Chinese Academy of SciencesBeijing 100190China Nanjing University of Information Science and Technology Nanjing 210044China Research Center for Eco-Environmental Sciences Chinese Academy of SciencesBeijing 100085China Institute of Earth Environment Chinese Academy of SciencesXi’an 710061China University of Science and Technology of China Hefei 230026China Tsinghua University Beijing 100084China Anhui Institute of Optics and Fine Mechanics Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China Jinan University Guangzhou 510632China Hong Kong Polytechnic University Hong Kong SARChina Beijing Institute of Technology Beijing 100081China

Atmospheric chemistry research has been growing rapidly in China in the last 25 years since the concept of the“air pollution complex”was first proposed by Professor Xiaoyan TANG in *** papers published in 2021 on air pollution(only papers included in the Web of Science Core Collection database were considered),more than 24000 papers were authored or co-authored by scientists working in *** this paper,we review a limited number of representative and significant studies on atmospheric chemistry in China in the last few years,including studies on(1)sources and emission inventories,(2)atmospheric chemical processes,(3)interactions of air pollution with meteorology,weather and climate,(4)interactions between the biosphere and atmosphere,and(5)data *** intention was not to provide a complete review of all progress made in the last few years,but rather to serve as a starting point for learning more about atmospheric chemistry research in *** advances reviewed in this paper have enabled a theoretical framework for the air pollution complex to be established,provided robust scientific support to highly successful air pollution control policies in China,and created great opportunities in education,training,and career development for many graduate students and young *** paper further highlights that developing and low-income countries that are heavily affected by air pollution can benefit from these research advances,whilst at the same time acknowledging that many challenges and opportunities still remain in atmospheric chemistry research in China,to hopefully be addressed over the next few decades.

关键词： atmospheric chemistry air pollution complex theoretical framework recent progress

Purification and characterization of schizophyllan from Schizophyllum commune

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Engineering Sciences 2013年第2期11卷 88-92页

作者： Hao Limin Zhang Jianchun Wu Tianyi Zhang Jian lu Jike Wang Qizhi Zhang Xiaojuan Xing xinhui The Quartermaster Equipment Institute of GLD of CPLA High Altitude Medical Research Institute Jiangsu Province Academy of Traditional Chinese Medicine Department of Bioengineering Zhengzhou University Department of Chemical Engineering and Technology Tsinghua University

The schizophyllan from Schizophyllum commune was purified and characterized. The crude schizo-phyllan was obtained from Schizophyllum commune fermentation broth by decoloration with activated carbon,followed by deproteinization with Sevag method and ethanol precipitation. The pure schizophyllan was obtained by gel filtration chromatography with Sephacryl S-500,and its molecular characteristics were examined. The result showed that the molecular weight was 3.8×104 ,and the schizophyllan consisted of glucose with β-(1→6)-glucosidic linkages.

关键词：纯化凝胶过滤色谱法表征 Sevag法乙醇沉淀分子特性裂褶多糖活性炭