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Rice GLUTATHIONE PEROXIDASE1-mediated oxidation of bZIP68 positively regulates ABA-independent osmotic stress signaling

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Molecular Plant 2022年第4期15卷 651-670页

作者： Heng Zhou Feng Zhang Fengchao Zhai Ye Su Ying Zhou Zhenglin Ge Priyadarshini Tilak Jürgen Eirich Iris Finkemeier Ling Fu Zongmin Li Jing Yang Wenbiao shen xingxing Yuan Yanjie Xie Laboratory Center of Life Sciences College of Life SciencesNanjing Agricultural UniversityNanjing 210095PR China Institute for Biology and Biotechnology of Plants University of Muenster48149 MuensterGermany State Key Laboratory of Proteomics Beijing Proteome Research CenterNational Center 17 for Protein SciencesBeijingBeijing Institute of LifeomicsBeijing 102206China Institute of Industrial Crops Jiangsu Academy of Agricultural SciencesNanjing 210014China

Osmotic stress caused by drought and high salinity is a significant environmental threat that limits plant growth and agricultural yield. Redox regulation plays an important role in plant stress responses, but the mechanisms by which plants perceive and transduce redox signals are still underexplored. Here, we report a critical function for the thiol peroxidase GPX1 in osmotic stress response in rice, where it serves as a redox sensor and transducer. GPX1 is quickly oxidized upon exposure to osmotic stress and forms an intramolecular disulfide bond, which is required for the activation of bZIP68, a VRE-like basic leucine zipper (bZIP) transcription factor involved in the ABA-independent osmotic stress response pathway. The disulfide exchange between GPX1 and bZIP68 induces homo-tetramerization of bZIP68 and thus positively regulates osmotic stress response by regulating osmotic-responsive gene expression. Furthermore, we discovered that the nuclear translocation of GPX1 is regulated by its acetylation under osmotic stress. Taken together, our findings not only uncover the redox regulation of the GPX1-bZIP68 module during osmotic stress but also highlight the coordination of protein acetylation and redox signaling in plant osmotic stress responses.

关键词： GPX1 SOH oxidative stress acetylation ZIP68 transactivation

GaN-based substrates and optoelectronic materials and devices

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Chinese Science Bulletin 2014年第12期59卷 1201-1218页

作者： Guoyi Zhang Bo shen Zhizhong Chen Xiaodong Hu Zhixin Qin Xinqiang Wang Jiejun Wu Tongjun Yu Xiangning Kang xingxing Fu Wei Yang Zhijian Yang Zhizhao Gan State Key Laboratory for Artificial Microstructures and Mesoscopic Physics School of PhysicsPeking University Research Center for Wide Bandgap Semiconductors Peking University

In order to solve the problems of GaN heteroepitaxy on sapphire substrate,some techniques were *** GaN substrates have been made by hydride vapor phase epitaxy(HVPE),laser lift-off(LLO),and chemical mechanical polishing *** bending and cracking in the HVPE growth were partly settled by pulsed flow modulation ***-crystal quality was established for 1.2 mm thick GaN substrate by X-ray diffraction measurement,in which the full width of half maximum values were 72,110 arcsec for(102),(002)peaks.A novel micro-size patterned sapphire substrate(PSS)and a nano PSS were also ***-power vertical structure light emitting diodes(VSLEDs)have been developed by Au–Sn eutectic wafer bonding,homemade micro-area LLO,and light extraction structure *** high-injection-level active region with low temperature GaN sandwiched layers was used for lowefficiency *** light output power of VSLED was achieved as 400 mW driven at 350 mA,and the dominant wavelength is about 460 *** structures and properties of strain modulated superlattices(SLs)and quantum wells as well as advanced simulation of carriers transport across the electron blocking layer were investigated in laser *** hole concentration was achieved as high as1.6 9 1018cm-3in AlGaN/GaN SLs:Mg by inserting an AlN ***-quality AlGaN epilayers and structures were grown by *** device structures of UV LEDs and detectors were *** emission wavelength of 262 nm UV LED has been successfully *** last,high-quality InN and InGaN materials for solar cell were grown by boundary-temperature-controlled epitaxy and growth-temperature-controlled ***-effect measurement showed a recorded electron mobility of 3,280 cm2/(V s)and a residual electron concentration of 1.47 9 1017cm-3at 300 K.

关键词： AlGaN 蓝宝石衬底光电子材料 MOCVD生长氢化物气相外延激光二极管垂直结构器件

Enhanced photoelectrochemical water splitting using a cobalt-sulfide-decorated BiVO_(4) photoanode

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Chinese Journal of Catalysis 2022年第2期43卷 433-441页

作者： Zhiming Zhou Jinjin Chen Qinlong Wang xingxing Jiang Yan shen Wuhan National Laboratory for Optoelectronics Huazhong University of Science and TechnologyWuhan 430074HubeiChina China‐EU Institute for Clean and Renewable Energy Huazhong University of Science and TechnologyWuhan 430074HubeiChina

Solar-driven water splitting is considered as a promising method to mitigate the energy crisis and various environmental *** vanadate(BiVO_(4))is photoanode material with tremendous potential for photoelectrochemical(PEC)water ***,its PEC performance is severely hindered owing to poor surface charge transfer,surface recombination at the photoanode/electrolyte junction,and sluggish oxygen evolution reaction(OER)*** this regard,a novel solution was developed in this study to address these issues by decorating the surface of BiVO_(4)with cobalt sulfide,whose attractive features such as low cost,high conductivity,and rapid charge-transfer ability assisted in improving the PEC activity of the BiVO_(4)*** fabricated photoanode exhibited a significantly enhanced photocurrent density of 3.2 m A cm^(-2)under illumination at 1.23 V vs.a reversible hydrogen electrode,which is more than 2.5 times greater than that of pristine BiVO_(4).Moreover,the Co S/BiVO_(4)photoanode also exhibited considerable improvements in the charge injection yield(75.8%vs.36.7%for the bare BiVO_(4)film)and charge separation efficiency(79.8%vs.66.8%for the pristine BiVO_(4)film).These dramatic enhancements were primarily ascribed to rapid charge-transport kinetics and efficient reduction of the anodic overpotential for oxygen evolution enabled by the surface modification of BiVO_(4)by Co *** study provides valuable suggestions for designing efficient photocatalysts via surface modification to improve the PEC performance.

关键词： Photoelectrochemical water splitting Bismuth vanadate Cobalt sulfide Charge separation and transfer Photoanode

Iterative HOEO fusion strategy:a promising tool for enhancing bearing fault feature

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Frontiers of Mechanical Engineering 2023年第1期18卷 253-273页

作者： xingxing JIANG Demin PENG Jianfeng GUO Jie LIU Changqing shen Zhongkui ZHU School of Rail Transportation Soochow UniversitySuzhou 215131China China Academy of Railway Sciences Co.Ltd. Beijing 100094China School of Civil and Hydraulic Engineering Huazhong University of Science and TechnologyWuhan 430074China

As parameter independent yet simple techniques,the energy operator(EO)and its variants have received considerable attention in the field of bearing fault feature ***,the performances of these improved EO techniques are subjected to the limited number of EOs,and they cannot reflect the non-linearity of the machinery dynamic systems and affect the noise *** a result,the fault-related transients strengthened by these improved EO techniques are still subject to contamination of strong *** address these issues,this paper presents a novel EO fusion strategy for enhancing the bearing fault feature nonlinearly and ***,the proposed strategy is conducted through the following three ***,a multi-dimensional information matrix(MDIM)is constructed by performing the higher order energy operator(HOEO)on the analysis signal *** is regarded as the fusion source of the proposed strategy with the properties of improving the signal-to-interference ratio and suppressing the noise in the low-frequency ***,an enhanced manifold learning algorithm is performed on the normalized MDIM to extract the intrinsic manifolds correlated with the fault-related ***,the intrinsic manifolds are weighted to recover the fault-related *** studies and experimental verifications confirm that the proposed strategy is more effective for enhancing the bearing fault feature than the existing methods,including HOEOs,the weighting HOEO fusion,the fast Kurtogram,and the empirical mode decomposition.

关键词： higher order energy operator fault diagnosis manifold learning rolling element bearing information fusion

面向社区生活圈构建的郊区居民社区依赖性研究——以上海市为例

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地理科学进展 2019年第6期38卷 818-828页

作者：傅行行申悦南京大学建筑与城市规划学院南京210093 华东师范大学城市与区域科学学院上海200062 华东师范大学中国现代城市研究中心上海200062

在郊区化和社区生活圈构建的背景下,提高郊区居民日常生活对社区空间的依赖性对于缓解城市发展压力、提高居民生活质量和满意度有重要意义。论文将功能性依赖和情感性依赖2个维度相结合,构建研究框架,将居民的社区依赖性划分为社区依赖... 详细信息

在郊区化和社区生活圈构建的背景下,提高郊区居民日常生活对社区空间的依赖性对于缓解城市发展压力、提高居民生活质量和满意度有重要意义。论文将功能性依赖和情感性依赖2个维度相结合,构建研究框架,将居民的社区依赖性划分为社区依赖、社区依靠、社区认同和社区排斥4种类型。以上海市为案例地区开展实证研究,基于2017年郊区居民行为调查的一手数据,分析居民功能性依赖和情感性依赖的基本特征及其群体间差异,并利用多项Logistics回归模型,研究社区空间特征对社区依赖性的影响。对不同群体和不同社区特征下社区依赖性的模式进行总结,以期为郊区社区生活圈规划提供研究依据。研究结果表明:不同群体的社区依赖性特征存在显著差异,小汽车拥有情况对于功能性依赖和情感性依赖的作用方向相反;社区设施密度主要影响居民对社区的功能性依赖;社区绿地率对功能性依赖和情感性依赖都有显著的积极影响;居民对社区的主观评价主要影响情感性依赖。社区生活圈的规划应改善社区环境质量,合理配置绿地、开敞空间和休闲设施,提高社区商业设施等级和质量,同时也要注重加强社会环境的建设。

关键词：社区依赖性社区生活圈社区归属感上海郊区

Research Progress of Traditional Chinese Medicine in Treating Dysphagia After Stroke

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Journal of Clinical and Nursing Research 2021年第6期5卷 142-146页

作者： xingxing Shu Sina Feng Liduo shen Ruochen Jiang Hui Zhang Shaanxi University of Traditional Chinese Medicine Xianyang 712046Shaanxi ProvinceChina Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine Xianyang 712046Shaanxi ProvinceChina

Dysphagia is a common complication after stroke,which does not only affect the quality of life of patients,but also increase the risk of *** Chinese medicine(TCM)treatment has always played an important role in the clinical treatment of dysphagia after stroke,but its mechanism has not been fully *** on the use of TCM for the disease in the recent 5 years have been reviewed,and the problems existing in the development and treatment of the disease are discussed in this article,in an attempt to provide new ideas for the treatment of the *** paper presents a summary of traditional Chinese medicine treatment for the disease in the past five years,including traditional Chinese medicine compound and acupuncture.

关键词： Stroke Dysphagia Traditional Chinese medicine treatment Review

社区主客观特征对社区满意度的影响机理——以上海市郊区为例

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地理科学进展 2019年第5期38卷 686-697页

作者：申悦傅行行华东师范大学中国现代城市研究中心上海200062 华东师范大学城市与区域科学学院上海200062 南京大学建筑与城市规划学院南京210093

在以人为本发展理念的指导下,城市研究与规划越来越关注城市生活空间的构建与居民生活质量的提升,社区满意度研究的重要性不断增加。在郊区快速发展和社区生活圈构建的背景下,论文基于对上海市郊区居民活动日志调查的一手数据,在Campbel... 详细信息

在以人为本发展理念的指导下,城市研究与规划越来越关注城市生活空间的构建与居民生活质量的提升,社区满意度研究的重要性不断增加。在郊区快速发展和社区生活圈构建的背景下,论文基于对上海市郊区居民活动日志调查的一手数据,在Campbell模型的基础上建立理论模型,从客观和主观相结合的视角出发,聚焦社区客观建成环境、社区主观感知特征和社区满意度三者之间的影响机理,并利用结构方程模型开展实证研究。研究结果表明:居民的社区感知情况对社区满意度有直接性和决定性的影响,居民对社区的健康、便利、安全和美观情况的感知对社区满意度都存在显著的正影响;社区的密度、可达性、设施等客观建成环境通过影响社区感知特征而间接地影响社区满意度;居民的社会经济属性对社区感知特征和社区满意度的影响甚微,影响郊区居民社区满意度的主要因素是社区特征。

关键词：建成环境社区感知特征社区生活圈结构方程模型郊区上海

枳壳甘草汤调控炎性小体改善腰椎间盘突出症痛敏的实验研究

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中国中医骨伤科杂志 2024年第1期32卷 13-19页

作者：张擎天黄泽灵陈华段星星陆斌杰沈晓峰李宇卫徐波南京中医药大学附属苏州中医医院江苏苏州215100

目的:探讨髓核组织Nod样受体蛋白3(NLRP3)炎性小体活化对酸敏感离子通道3(ASIC3)所介导痛敏环节的激活作用,研究枳壳甘草汤改善腰椎间盘突出症(Lumbar Disc Herniation,LDH)疼痛的干预机制。方法:将60只SD大鼠随机分为空白组、模型组、C... 详细信息

目的:探讨髓核组织Nod样受体蛋白3(NLRP3)炎性小体活化对酸敏感离子通道3(ASIC3)所介导痛敏环节的激活作用,研究枳壳甘草汤改善腰椎间盘突出症(Lumbar Disc Herniation,LDH)疼痛的干预机制。方法:将60只SD大鼠随机分为空白组、模型组、Caspase-1抑制剂组、中药低剂量组(生药3 g/kg)、中药中剂量组(生药6 g/kg)、中药高剂量组(生药12 g/kg)每组10只。除空白组外,各组大鼠进行腰椎间盘突出症造模5 d后,进行相应干预及灌胃给药,持续20 d。于造模前及造模后5,12,19 d测定各组大鼠机械与冷刺激缩足阈值。取材后用苏木精-伊红(HE)染色检测椎间盘退变程度,免疫组化检测髓核组织Caspase-1p10的表达,ELISA法检测血清中IL-6、TNF-α、IL-1β的含量,蛋白免疫印迹法(Western Blot)检测椎间盘组织NLRP3、Caspase-1p10与背根神经节(Dorsal Root Ganglion,DRG)中ASIC3的表达,实时聚合酶链式反应(RT-PCR)检测背根神经节中ASIC3的mRNA表达。结果:机械与冷刺激缩足阈值结果:腰椎间盘突出症模型组大鼠表现出典型的冷痛敏和机械痛敏状态,抑制剂组、枳壳甘草汤治疗各组中大鼠痛敏状态均获缓解,冷刺激与机械刺激缩足阈值均较模型组有明显改善,差异有统计学意义(P<0.05)。HE染色结果:腰椎间盘突出症模型组大鼠纤维环排列紊乱,部分肿胀断裂;抑制剂组及枳壳甘草汤治疗各组与模型组相比,纤维环排列均较为有序,且纤维环无明显断裂。免疫组化结果:与模型组相比,枳壳甘草汤治疗组免疫组化Caspase-1p10平均光密度更弱,差异有统计学意义(P<0.05)。ELISA检测结果:治疗各组较模型组炎症因子IL-6、IL-1β、TNF-α表达均显著下降,差异有统计学意义(P<0.05)。PCR结果:抑制剂组及枳壳甘草汤治疗各组与模型组相比,ASIC3的mRNA表达均显著下降,差异有统计学意义(P<0.05)。Western Blot结果:抑制剂组及枳壳甘草汤治疗各组与模型组相比,NLRP3、Caspase-1p10、ASIC3蛋白表达水平均出现显著下降,差异有统计学意义(P<0.05)。结论:NLRP3炎性小体的活化能够调控ASIC3的转录及功能,进而构建并维持腰椎间盘突出症的痛敏状态。枳壳甘草汤改善腰椎间盘突出症痛敏的机制与其对NLRP3炎性小体/ASIC3信号通路的调控有关。

关键词：枳壳甘草汤腰椎间盘突出症炎性小体酸敏感离子通道

天然模板法多孔TiO2遗态材料的制备及其光催化性能

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河北科技师范学院学报 2020年第1期34卷 46-55页

作者：韩丽娜李泽民孙明功冯博涵赵初蕾王薇妍魏巍宋鹏飞王利江宋士涛张志伟沈星星河北科技师范学院化学工程学院河北秦皇岛066600

为确定酸碱预处理及浸渍时间的长短对遗态材料光催化性能的影响,以稻壳为模板,采用一种简便的天然模板法合成了具有生物形态的TiO2遗态材料,使用XRD,SEM,TEM,BET对材料的组成及形貌进行了表征,并对其进行了光催化性能测试。结果表明:用... 详细信息

为确定酸碱预处理及浸渍时间的长短对遗态材料光催化性能的影响,以稻壳为模板,采用一种简便的天然模板法合成了具有生物形态的TiO2遗态材料,使用XRD,SEM,TEM,BET对材料的组成及形貌进行了表征,并对其进行了光催化性能测试。结果表明:用质量分数0.01的盐酸进行预处理,浸渍时间为1h,煅烧温度为500℃,所制备的遗态TiO 2比表面积达到345.7m2·g-1,光催化性能最佳,对亚甲基的光催化降解率可高达93%以上。

关键词： TiO2遗态材料天然模板法稻壳光催化性能