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Effect of cold stratification on the temperature range for germination of Pinus koraiensis

Journal of Forestry Research 2023年第1期34卷 221-231页

作者： Yuan Song Xinghuan Li Mingyi Zhang Guowei Xia Chao Xiong College of Eco-Environmental Engineering Guizhou Minzu UniversityGuiyangPeople’s Republic of China Qingyuan Forest CERN Chinese Academy of SciencesShenyang 110016People’s Republic of China Karst Environmental Geological Hazard Prevention Laboratory of Guizhou Minzu University GuiyangPeople’s Republic of China Guiyang Institute of Information Science and Technology GuiyangPeople’s Republic of China

Germination at low spring temperatures may offer a competitive advantage for the growth and survival of plant species inhabiting temperate forest ecosystems.Pinus koraiensis is a dominant species in temperate forests of northeastern China.Its seeds exhibit primary morphophysiological dormancy following dispersal in autumn,limiting natural or artificial regeneration:direct seeding and planting seedlings in spring.The aim of this study was to determine the optimum cold stratification temperature that induces germination to increase towards lower temperatures.Seeds from two populations(Changbaishan and liangshui)were cold stratified at 0,5 and 10℃.Germination to incubation temperatures(10/5,20/10,25/15 and 30/20℃;14/10 h day/night)were determined after 2 and 4 weeks,and 5.5 and6.5 months of cold stratification.After 5.5 months,approximately 68-91%of seeds from both populations germinated at incubation temperatures of 25/15℃and 30/20℃,regardless of cold stratification temperatures.When the cold stratification temperature was reduced to 0℃and the period increased to 6.5 months,germination at 10/5℃significantly improved,reaching 37%and 64%for the Changbaishan and liangshui populations,respectively.After 6.5 months of cold stratification,there was a significant linear regression between cold stratification temperatures and germination at10/5℃.The range in temperatures allowing for germination gradually expanded to include lower temperatures with decreasing cold stratification temperatures from 10 to 5℃and further to 0℃.

关键词： Cold Stratification temperatures Pinus koraiensis Seed germination Germination temperature range

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Advanced materials for the delivery of vaccines for infectious diseases

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Biosafety and Health 2022年第2期4卷 95-104页

作者： Wei li Junli Meng xinghuan Ma Jiaqi lin Xueguang Lu Beijing National Laboratory for Molecular Sciences Key Laboratory of ColloidInterface and Chemical ThermodynamicsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China School of Chemical Sciences University of Chinese Academy of SciencesBeijing 100049China Key State Laboratory of Fine Chemicals School of BioengineeringDalian University of TechnologyDalian 116024China

Infectious diseases are an increasing threat to global biosafety.Vaccination is the most effective and costefficient method for preventing and controlling infectious diseases.The development of new vaccines is inextricably linked to the advancement of materials that serve as essential components of vaccines,such as antigens,adjuvants,and their carriers.The physicochemical and biological properties of vaccines-such as the kinetics of antigen retention and presentation-are determined by the material compositions of vaccines and carriers,affecting the overall efficacy.The sustained release of antigens prolongs their retention time in germinal centers and improves humoral immune responses.Pulsatile release that imitates clinical dosing regimens can improve patient adherence to vaccination,affording increased vaccine coverage.Herein,we review progress of materials innovation on altering vaccine release kinetics,which affects the overall vaccine efficacy,safety,and compliance.

关键词： Infectious disease Vaccine Biosafety material Vaccine delivery Release kinetics

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3D-printed tissue repair patch combining mechanical support and magnetism for controlled skeletal muscle regeneration

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Bio-Design and Manufacturing 2022年第2期5卷 249-264页

作者： Xiaocheng Wang Ruibo Zhao Jian Wang Xinghuan Li lijuan Jin Wenyu liu lifang Yang Yonghua Zhu Zhikai Tan College of Biology Hunan UniversityChangsha 410082China Department of Orthopaedics Xiangya HospitalCentral South UniversityChangsha 410008China Key Laboratory of Carcinogenesis and Cancer Invasions of Ministry of Education School of Basic Medicine ScienceCancer Research InstituteCentral South UniversityChangsha 410008China

Physical forces,such as magnetic and mechanical stimulation,are known to play a significant role in the regulation of cell response.In the present study,a biomimetic regeneration patch was fabricated using E-jet 3 D printing,which integrates mechanical and magnetic stimulation in a biocompatible"one-pot reaction"strategy when combined with a static magnetic field(SMF).The magneto-based therapeutic regeneration patch induced myoblasts to form aligned and multinucleated myotubes,regulated the expression of myogenic-related genes,and activated the p38αmitogen-activated protein kinase pathway via the initiation of myogenic differentiation.To validate the efficiency of the proposed strategy,the regeneration patch was implanted into mice and exposed to a suitable SMF,which resulted in significantly enhanced in vivo skeletal muscle regeneration.The findings demonstrated that appropriate external physical stimulation provides a suitable biophysical microenvironment that is conducive to tissue regeneration.The method used in the present study represents a promising technique to induce the regeneration of damaged skeletal muscle tis sue.

关键词： Functional biomaterials Magnetic actuation Myogenic differentiation Skeletal muscle regeneration 3D printing

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Experimental Study of Mode-I and Mode-II Interlaminar Fracture Characteristics of Poplar LVL

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Journal of Renewable Materials 2023年第1期11卷 245-255页

作者： Zhongping Xiao Chen li Biqing Shu Shukai Tang xinghuan Yang Yan liu College of Civil Engineering Yangzhou Polytechnic InstituteYangzhou225127China College of Civil Science and Engineering Yangzhou UniversityYangzhou225127China

Fracture is a common failure form of poplar laminated veneer lumber(LVL).In the present work,we performed an experimental study on the mode-I along-grain interlaminar fracture,mode-I cross-grain interlaminar fracture,and mode-II interlaminar fracture of poplar LVL.We investigated stress mechanisms,failure modes,and fracture toughness values of the different fracture types.The experimental results revealed that the crack in the mode-I along-grain interlaminar fracture specimen propagated along the prefabricated crack direction,and the crack tip broke.The mode-I cross-grain interlaminar fracture specimen had cracks in the vertical direction near the prefabricated crack.In the mode-II interlaminar fracture specimen,cracks appeared along the initial prefabricated crack direction.The load–displacement curves of these three specimens were linear in the early stage of loading.With the increase in the load,a nonlinear segment appeared before crack propagation and a descending segment appeared after crack propagation.The nonlinear segments of the mode-I along-grain interlaminar fracture and mode-II interlaminar fracture were very short,and cracks expanded quickly after their initiation,resulting in brit-tle fracture.The nonlinear segment of the mode-I cross-grain interlaminar fracture was long,resulting in plastic failure.The average toughness values of the mode-I along-grain interlaminar fracture,mode-I cross-grain inter-laminar fracture,and mode-II interlaminar fracture were 15.43,270.15,and 39.72 MPa·mm^(1/2),respectively.

关键词： Poplar LVL crack propagation fracture toughness

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Accurate and efficient pulmonary CT imaging workflow for COVID-19 patients by the combination of intelligent guided robot and automatic positioning technology

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Intelligent Medicine 2021年第1期1卷 3-9页

作者： Yadong Gang Xiongfeng Chen Hanlun Wang Jianying li Ying Guo Bin Wen Jinxiang Hu Haibo Xu xinghuan Wang Department of Radiology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Department of Radiology Puren Hospital affiliated to Wuhan University of Science and TechnologyWuhan 430080China GE Healthcare Computed Tomography Research CenterBeijing 100176China TAMI Intelligence Technology(Beijing)Co.Ltd Beijing 100176China Department of Urology Zhongnan Hospital of Wuhan UniversityWuhan 430071China Center for Evidence-based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan 430071China

Background:The ongoing coronavirus disease 2019(COVID-19)pandemic has put radiologists at a higher risk of infection during the computer tomography(CT)examination for the patients.To help settling these problems,we adopted a remote-enabled and automated contactless imaging workflow for CT examination by the combination of intelligent guided robot and automatic positioning technology to reduce the potential exposure of radiologists to 2019 novel coronavirus(2019-nCoV)infection and to increase the examination efficiency,patient scanning accuracy and better image quality in chest CT imaging.Methods:From February 10 to April 12,2020,adult COVID-19 patients underwent chest CT examinations on a CT scanner using the same scan protocol except with the conventional imaging workflow(CW group)or an automatic contactless imaging workflow(AW group)in Wuhan Leishenshan Hospital(China)were retrospectively and prospectively enrolled in this study.The total examination time in two groups was recorded and compared.The patient compliance of breath holding,positioning accuracy,image noise and signal-to-noise ratio(SNR)were assessed by three experienced radiologists and compared between the two groups.Results:Compared with the CW group,the total positioning time of the AW group was reduced((118.0±20.0)s vs.(129.0±29.0)s,P=0.001),the proportion of scanning accuracy was higher(98%vs.93%),and the lung length had a significant difference((0.90±1.24)cm vs.(1.16±1.49)cm,P=0.009).For the lesions located in the pulmonary centrilobular and subpleural regions,the image noise in the AW group was significantly lower than that in the CW group(centrilobular region:(140.4±78.6)HU vs.(153.8±72.7)HU,P=0.028;subpleural region:(140.6±80.8)HU vs.(159.4±82.7)HU,P=0.010).For the lesions located in the peripheral,centrilobular and subpleural regions,SNR was significantly higher in the AW group than in the CW group(centrilobular region:6.6±4.3 vs.4.9±3.7,P=0.006;subpleural region:6.4±4.4 vs.4.8±4.0,P<0.001).Conclusions:The automatic contactless imaging work

关键词： Coronavirus disease 2019 Artificial intelligence Robotics Computer tomography

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“互联网+”背景下高等职业教育模式的创新

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科技创新导报 2021年第32期18卷 168-171页

作者：李兴环临汾职业技术学院山西临汾041000

当前我国互联网技术迅猛发展,在“互联网+”背景下,传统的教学模式已经无法满足教育发展需求,创新高等职业教育模式显得尤为重要。为了更好地提升高职学生的综合能力,学校应改革传统的教育方式。基于此,本文从当前高等职业教育存在的问... 详细信息

当前我国互联网技术迅猛发展,在“互联网+”背景下,传统的教学模式已经无法满足教育发展需求,创新高等职业教育模式显得尤为重要。为了更好地提升高职学生的综合能力,学校应改革传统的教育方式。基于此,本文从当前高等职业教育存在的问题出发,对高等职业教育模式的构建进行分析,并就“互联网+”背景下高等职业教育模式的创新策略进行详细论述。

关键词：互联网+ 高等职业教育模式创新模式

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盐酸羟考酮缓释片对晚期恶性肿瘤中重度疼痛的效果分析

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北方药学 2019年第5期16卷 11-12页

作者：李杏欢广东省博罗县人民医院肿瘤科惠州516100

目的:分析盐酸羟考酮缓释片治疗晚期恶性肿瘤中重度疼痛的临床效果。方法:选定本院收治的晚期恶性肿瘤中重度疼痛患者56例,研究时段2015年1月~2018年6月,在随机数表法的分组原则下,分为试验组(28例,盐酸羟考酮缓释片治疗)、对照组(28例... 详细信息

目的:分析盐酸羟考酮缓释片治疗晚期恶性肿瘤中重度疼痛的临床效果。方法:选定本院收治的晚期恶性肿瘤中重度疼痛患者56例,研究时段2015年1月~2018年6月,在随机数表法的分组原则下,分为试验组(28例,盐酸羟考酮缓释片治疗)、对照组(28例,硫酸吗啡缓释片治疗),比较临床疗效、KPS评分、不良反应。结果:试验组临床总有效率高于对照组,差异无统计学意义(P>0.05);试验组KPS评分显著高于对照组,差异具有统计学意义(P>0.05);试验组不良反应发生率低于对照组,差异具有统计学意义(P<0.05)。结论:盐酸羟考酮缓释片可有效减轻晚期恶性肿瘤患者疼痛程度,且不良反应较少,值得借鉴。

关键词：盐酸羟考酮缓释片晚期恶性肿瘤中重度疼痛临床效果

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基于EMD方法的X波段双偏振雷达衰减订正

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雷达科学与技术 2022年第2期20卷 119-127页

作者：李海冯兴寰孟凡旺中国民航大学天津市智能信号与图像处理重点实验室天津300300 中国航空工业集团公司雷华电子技术研究所江苏无锡210403

针对X波段双偏振雷达信号在降雨路径中的衰减现象,本文提出经验模式分解(Empirical Mode Decomposition,EMD)方法进行X波段双偏振雷达衰减订正,首先对总差分传播相移进行EMD分解得到有限个基本模式分量(Intrinsic Mode Function,IMF),... 详细信息

针对X波段双偏振雷达信号在降雨路径中的衰减现象,本文提出经验模式分解(Empirical Mode Decomposition,EMD)方法进行X波段双偏振雷达衰减订正,首先对总差分传播相移进行EMD分解得到有限个基本模式分量(Intrinsic Mode Function,IMF),并基于皮尔逊相关系数准则将IMF分为噪声IMF和信号IMF两类,然后对信号IMF进行有效重构得到差分传播相移,再将差分传播相移通过最小二乘法拟合得到差分传播相移率,最后对求得的差分传播相移与差分传播相移率采用自适应约束方法进行反射率衰减订正。利用EMD方法和其他方法进行对比分析,其结果表明,EMD方法能够有效地消除X波段双偏振雷达回波数据中后向散射的影响,在保留真实的气象信息的同时,有效地抑制差分传播相移的显著波动,进而衰减订正效果更好。

关键词：双偏振雷达差分传播相移经验模式分解衰减订正

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内脏异位综合征患儿围手术期灾难性血流动力学变化1例

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中国分子心脏病学杂志 2022年第2期22卷 4629-4632页

作者：李星寰贾爰云南省阜外心血管病医院麻醉科昆明市650102 国家心血管病中心中国医学科学院阜外医院麻醉中心北京市100037

1病例资料患儿,男,39天,3.7 kg,ASAⅣ级,因“孕18周发现胎儿心脏结构异常”入院。足月顺产,出生体重2.8 kg,无窒息抢救史;入院时精神一般,母乳喂养,二便正常;吸空气血氧饱和度(oxygen saturation,SpO_(2))85%~89%,吸氧后SpO_(2)92%~95%... 详细信息

1病例资料患儿,男,39天,3.7 kg,ASAⅣ级,因“孕18周发现胎儿心脏结构异常”入院。足月顺产,出生体重2.8 kg,无窒息抢救史;入院时精神一般,母乳喂养,二便正常;吸空气血氧饱和度(oxygen saturation,SpO_(2))85%~89%,吸氧后SpO_(2)92%~95%,四肢血压及氧饱和度无差异,皮肤轻度黄染,胸骨左缘第2~4肋间闻及收缩期吹风样杂音,余查体无特殊。入院后持续泵注前列地尔2 ng/(kg·min)维持PDA开放;持续心电监测提示阵发性室上性心动过速,术前间断发作4次,发作时心室率200~250次/分,无创血压下降不明显.

关键词：内脏异位综合征体肺分流术

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量子意识视域下的《夏伯阳与虚空》的后现代空间叙事

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俄罗斯文艺 2017年第1期 29-36页

作者：傅星寰李俊学辽宁师范大学文学院

在维克多·佩列文的后现代主义经典之作《夏伯阳与虚空》中,其多时空交错的结构和碎片化叙述,是这部后现代主义小说引起学界普遍关注的重要特征之一。若从量子力学的角度考量,这些繁复的时空交错和碎片化叙述,其实只显现出两种空间维度... 详细信息

在维克多·佩列文的后现代主义经典之作《夏伯阳与虚空》中,其多时空交错的结构和碎片化叙述,是这部后现代主义小说引起学界普遍关注的重要特征之一。若从量子力学的角度考量,这些繁复的时空交错和碎片化叙述,其实只显现出两种空间维度的本质,即现实空间和非现实空间,它们具有不确定性和相对性。"现实空间"指的是当下的空间载体,是意识主体临时寄居的客观的空间场所,具有短暂的真实性。"非现实空间"是相对于"现实空间"的"意识空间",指的是在当下的现实空间中,意识主体的精神场域,也可以说是意识主体临时的记忆空间,具有短暂的虚幻性,它们始终处于"迭加"与"坍缩"的动态隐含和凸显之中。本文尝试运用后现代主义空间理论、量子力学原理及量子心理学对这一现象进行探究,考察游移在两个空间维度中的书中人在空间迷失下的身份、信仰和精神的迷失状态,以及作者对当代俄罗斯的命运和俄罗斯的精神归属问题的深度思考。

关键词：夏伯阳与虚空后现代空间理论量子意识

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