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Loss of the accessory chromosome converts a pathogenic tree-root fungus into a mutualistic endophyte

Plant Communications 2024年第1期5卷 164-180页

作者： Huanshen Wei Zhenhui Zhong Zhongfeng Li Yuwei Zhang Eva H.Stukenbrock Boping Tang Ningning Yang Riccardo Baroncelli Long Peng Zhuo Liu xinghua he Yuzhan Yang Zhilin Yuan State Key Laboratory of Tree Genetics and Breeding Chinese Academy of ForestryBeijing 100091China Research Institute of Subtropical Forestry Chinese Academy of ForestryHangzhou 311400China State Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops Fujian Agriculture and Forestry UniversityFuzhou 350002China Environmental Genomics Christian-Albrechts University24118 KielGermany Max Planck Fellow Group Environmental Genomics Max Planck Institute for Evolutionary Biology24306 PlonGermany Jiangsu Key Laboratory for Bioresources of Saline Soils School of WetlandsYancheng Teachers UniversityYancheng 224002China Department of Agricultural and Food Sciences(DISTAL) University of Bologna40127 BolognaItaly

Some fungal accessory chromosomes(ACs)may contribute to virulence in ***,the mecha-nisms by which ACs determine specific traits associated with lifestyle transitions along a symbiotic contin-uum are not *** we delineated the genetic divergence in two sympatric but considerably variable isolates(16B and 16W)of the poplar-associated fungus Stagonosporopsis *** identified a-0.6-Mb horizontally acquired AC in 16W that resulted in a mildly parasitic lifestyle in *** deletion of the AC(D16W)significantly altered the fungal ***,D16W was morphologically more similar to 16B,showed enhanced melanization,and established beneficial interactions with poplar plants,thereby acting as a dark septate *** sequencing(RNA-seq)analysis showed that AC loss induced the upregulation of genes related to root colonization and biosynthesis of indole acetic acid and *** observed that the AC maintained a more open status of chromatin across the genome,indicating an impressive remodeling of cis-regulatory elements upon AC loss,which potentially enhanced symbiotic *** demonstrated that the symbiotic capacities were non-host-specific through comparable experiments on Triticum–and Arabidopsis–fungus ***,the three isolates generated symbiotic interactions with a nonvascular *** summary,our study suggests that the AC is a suppressor of symbiosis and provides insights into the underlying mechanisms of mutualism with vascular plants in the absence of traits encoded by the *** speculate that AC-situ-ated effectors and other potential secreted molecules may have evolved to specifically target vascular plants and promote mild virulence.

关键词： dark septate endophytes effectors lifestyle transition root–fungus symbioses

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Distributed Least Squares Algorithm of Continuous-Time Stochastic Regression Model Based on Sampled Data

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Journal of Systems Science & Complexity 2024年第2期37卷 609-628页

作者： ZHU xinghua GAN Die LIU Zhixin The Key Laboratory of Systems and Control Academy of Mathematics and Systems ScienceChinese Academy of Sciencesand School of Mathematical SciencesUniversity of Chinese Academy of SciencesBeijing 100190China Zhongguancun Laboratory Beijing 100094China

In this paper,the authors consider the distributed adaptive identification problem over sensor networks using sampled data,where the dynamics of each sensor is described by a stochastic differential *** minimizing a local objective function at sampling time instants,the authors propose an online distributed least squares algorithm based on sampled data.A cooperative non-persistent excitation condition is introduced,under which the convergence results of the proposed algorithm are established by properly choosing the sampling time *** upper bound on the accumulative regret of the adaptive predictor can also be ***,the authors demonstrate the cooperative effect of multiple sensors in the estimation of unknown parameters by computer simulations.

关键词： Cooperative excitation condition distributed least squares regret sampled data stochastic differential equation

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Distributed order estimation for continuous-time stochastic systems

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Control Theory and Technology 2024年第3期22卷 406-418页

作者： xinghua Zhu Zhixin Liu Xiaoming Hu Key Laboratory of Systems and Control Academy of Mathematics and Systems ScienceBeijing 100190China School of Mathematical Sciences University of Chinese Academy of SciencesBeijing 100190China Department of Mathematics KTH Royal Institute of TechnologyStockholm 10044Sweden

In this paper,we investigate the distributed estimation problem of continuous-time stochastic dynamic systems over sensor networks when both the system order and parameters are *** propose a local information criterion(LIC)based on the L_(0)penalty *** minimizing LIC at the diffusion time instant and utilizing the continuous-time diffusion least squares algorithm,we obtain a distributed estimation algorithm to simultaneously estimate the unknown order and the parameters of the *** dealing with the effect of the system noises and the coupling relationship between estimation of system orders and parameters,we establish the almost sure convergence results of the proposed distributed estimation ***,we give a simulation example to verify the effectiveness of the distributed algorithm in estimating the system order and parameters.

关键词： Stochastic differential equations Sensor networks Distributed order estimation Cooperative excitation condition.Convergence

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Collision-free parking recommendation based on multi-agent reinforcement learning in vehicular crowdsensing

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Digital Communications and Networks 2024年第3期10卷 609-619页

作者： Xin Li xinghua Lei Xiuwen Liu Hang Xiao College of Computer Science and Technology China University of Petroleum(East China)QingDao266580China

The recent proliferation of Fifth-Generation(5G)networks and Sixth-Generation(6G)networks has given rise to Vehicular Crowd Sensing(VCS)systems which solve parking collisions by effectively incentivizing vehicle ***,instead of being an isolated module,the incentive mechanism usually interacts with other *** on this,we capture this synergy and propose a Collision-free Parking Recommendation(CPR),a novel VCS system framework that integrates an incentive mechanism,a non-cooperative VCS game,and a multi-agent reinforcement learning algorithm,to derive an optimal parking strategy in real ***,we utilize an LSTM method to predict parking areas roughly for recommendations *** incentive mechanism is designed to motivate vehicle participation by considering dynamically priced parking tasks and social network *** order to cope with stochastic parking collisions,its non-cooperative VCS game further analyzes the uncertain interactions between vehicles in parking *** its multi-agent reinforcement learning algorithm models the VCS campaign as a multi-agent Markov decision process that not only derives the optimal collision-free parking strategy for each vehicle independently,but also proves that the optimal parking strategy for each vehicle is ***,numerical results demonstrate that CPR can accomplish parking tasks at a 99.7%accuracy compared with other baselines,efficiently recommending parking spaces.

关键词： Incentive mechanism Non-cooperative VCS game Multi-agent reinforcement learning Collision-free parking strategy Vehicular crowdsensing

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The Cement Solidification of Municipal Solid Waste Incineration Fly Ash

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Journal of Wuhan University of Technology(Materials Science) 2006年第4期21卷 137-140页

作者：侯浩波贺杏华 Institute of Resource and Environmental Science Wuhan University Wuhan 430079 China

The chemical composition, the content and the leachability of heavy metals in municipal solid waste incineration （ MSWI） fly ash were tested and analyzed. It is shown that the leachability of Pb and Cr exceeds the leaching toxicity standard, and so the MSWI fly ash is considered as hazardous waste and must be solidifled. The effect of solidifying the MSWI fly ash by cement was studied, and it is indicated that the heavy metals can be well immobilized if the mass fraction of the fly ash is appropriate. The heavy metals were immobilized within cement hydration products through either physical fixation, substhtaion, deposition or adsorption mechanisms.

关键词： MSWI fly ash heavy metals leaching toxicity cement solidification

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Mechanism of action of the bile acid receptor TGR5 in obesity

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Acta Pharmaceutica Sinica B 2024年第2期14卷 468-491页

作者： Weijun Lun Qihao Yan xinghua Guo Minchuan Zhou Yan Bai Jincan he Hua Cao Qishi Che Jiao Guo Zhengquan Su Guangdong Engineering Research Center of Natural Products and New Drugs Guangdong Provincial University Engineering Technology Research Center of Natural Products and DrugsGuangdong Pharmaceutical UniversityGuangzhou 510006China Guangdong Metabolic Disease Research Center of Integrated Chinese and Western Medicine Key Laboratory of Glucolipid Metabolic DisorderMinistry of Education of ChinaGuangdong TCM Key Laboratory for Metabolic DiseasesGuangdong Pharmaceutical UniversityGuangzhou 510006China School of Public health Guangdong Pharmaceutical UniversityGuangzhou 510310China School of Chemistry and Chemical Engineering Guangdong Pharmaceutical UniversityZhongshan 528458China Guangzhou Rainhome Pharm&Tech Co. Ltd.Science CityGuangzhou 510663China

G protein-coupled receptors(GPCRs)are a large family of membrane protein receptors,and Takeda G protein-coupled receptor 5(TGR5)is a member of this *** a membrane receptor,TGR5 is widely distributed in different parts of the human body and plays a vital role in regulating metabolism,including the processes of energy consumption,weight loss and blood glucose *** studies have shown that TGR5 plays an important role in glucose and lipid metabolism disorders such as fatty liver,obesity and *** the global obesity situation becoming more and more serious,a comprehensive explanation of the mechanism of TGR5 and filling the gaps in knowledge concerning clinical ligand drugs are urgently *** this review,we mainly explain the anti-obesity mechanism of TGR5 to promote the further study of this target,and show the electron microscope structure of TGR5 and review recent studies on TGR5 ligands to illustrate the specific binding between TGR5 receptor binding sites and ligands,which can effectively provide new ideas for ligand research and promote drug research.

关键词： Obesity TGR5 Bile acids Ligand Appetite Metabolism GLP-1 Inflammation

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交响诗《心潮逐浪高》主题乐思的旋律学分析

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中国音乐学 2023年第3期3卷 130-142页

作者：何兴华中国艺术研究院音乐学系四川音乐学院

交响诗《心潮逐浪高》是陈培勋先生于1960年根据毛泽东词《菩萨蛮·黄鹤楼》创作的一部极具民族风格的作品。本文以赵宋光先生提出的“五度相生调式体系”为基础,全面剖析该作品主题乐思构造,分析旋法技巧与调发展逻辑,并对作品审美意... 详细信息

交响诗《心潮逐浪高》是陈培勋先生于1960年根据毛泽东词《菩萨蛮·黄鹤楼》创作的一部极具民族风格的作品。本文以赵宋光先生提出的“五度相生调式体系”为基础,全面剖析该作品主题乐思构造,分析旋法技巧与调发展逻辑,并对作品审美意蕴做进一步解读。笔者亦期望借此个案说明“五度相生调式体系”在我国现当代音乐研究中的理论价值与应用潜力。

关键词：交响诗《心潮逐浪高》陈培勋赵宋光五度相生调式体系旋律学分析

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城市规划下乡六十年的反思与启示

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城市发展研究 2019年第10期26卷 1-11页

作者：何兴华住房和城乡建设部

以政府部门工作为主线,对过去六十年来城市规划下乡的背景、做法、经验、效果进行了简要的归纳,对不同阶段城市规划下乡遇到的实际问题和政府推动工作的方式,以及专业发展自身的规律进行了反思。认为,每个自然村和集镇都单独编制规划很... 详细信息

以政府部门工作为主线,对过去六十年来城市规划下乡的背景、做法、经验、效果进行了简要的归纳,对不同阶段城市规划下乡遇到的实际问题和政府推动工作的方式,以及专业发展自身的规律进行了反思。认为,每个自然村和集镇都单独编制规划很困难,也没有必要,应当在县市、乡镇规划指导下对居民点进行分类,再确定单个居民点是否需要单独编制规划。规划编制应当提供建设、保护、复耕等多种不同的"套餐",而不是用一个万能的模式。城乡规划是一个学科,城市规划是其重中之重,乡村规划是其重要组成部分。城乡规划并不是规划的全部,需要与其他规划进行协调整合。只有将城乡居民点变迁的规律作为专业研究的重点,城市的重要性和城乡规划的科学性才能得到真正的提高。城市问题与乡村问题互为因果,城市发展与乡村振兴是同一件事情的两个方面,其长久动力源自城镇化过程中城乡关系的改善。需要摆脱部门主义和学科偏见,努力改变城市规划主导乡村规划的局面,从更宽泛的人居实践视野,用人居科学理念和复杂适应系统理论指导城乡规划的发展,促进人居环境的改善。

关键词：乡村规划规划协调政府作用历史回顾

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Frequency-modulated continuous-wave multiplexed gas sensingbased on optical frequency comb calibration

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Chinese Physics B 2024年第9期33卷 152-163页

作者： Linhua Jia xinghua Qu Fumin Zhang State Key Laboratory of Precision Measurement Technology and Instruments Tianjin UniversityTianjin 300072China

Laser absorption spectroscopy has proven to be an effective approach for gas sensing, which plays an important rolein the fields of military, industry, medicine and basic research. This paper presents a multiplexed gas sensing system basedon optical frequency comb (OFC) calibrated frequency-modulated continuous-wave (FMCW) tuning nonlinearity. Thesystem can be used for multi-parameter synchronous measurement of gas absorption spectrum and multiplexed opticalpath. Multi-channel parallel detection is realized by combining wavelength division multiplexing (WDM) and frequencydivision multiplexing (FDM) techniques. By introducing nonlinear optical crystals, broadband spectrum detection is simultaneouslyachieved over a bandwidth of hundreds of nanometers. An OFC with ultra-high frequency stability is used asthe frequency calibration source, which guarantees the measurement accuracy. The test samples involve H13C14N, C_(2)H_(2)and Rb vapor cells of varying densities and 5 parallel measurement experiments are designed. The results show that themeasurement accuracies of spectral absorption line and the optical path are 150 MHz and 20 m, respectively. The schemeoffers the advantages of multiplexed, multi-parameter, wide spectrum and high resolution detection, which can realize theidentification of multi-gas components and the high-precision inversion of absorption lines under different *** proposed sensor demonstrates great potential in the field of high-resolution absorption spectrum measurement for gassensing applications.

关键词： frequency-modulated continuous-wave (FMCW) technology optical frequency comb multiplexing absorption spectroscopy

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科学实在的理解与城市规划的认知对象

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城市规划 2007年第6期31卷 16-20页

作者：何兴华建设部外事司

分析了科学哲学思潮对于城市规划理论的一般性影响,重点讨论了科学实在论对于认清城市规划学科认知对象的作用。文章指出,现实的城市已经是人们根据对于“自在实在”的认识采取行动的结果,是一种“对象性实在”的体现。城市规划学科仅... 详细信息

分析了科学哲学思潮对于城市规划理论的一般性影响,重点讨论了科学实在论对于认清城市规划学科认知对象的作用。文章指出,现实的城市已经是人们根据对于“自在实在”的认识采取行动的结果,是一种“对象性实在”的体现。城市规划学科仅仅停留在对于已有“城市”和“规划”的认识是不够的。由于人特别其个体活动的空间需求具有客观性,城市规划学科存在着建构“科学实在”的可能性。

关键词：科学实在城市规划认知对象

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