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细菌金属离子外排系统及金属稳态调控

微生物学报 2024年第3期64卷 672-686页

作者：董欣楠邓思敏宋厚辉徐加利程昌勇浙江农林大学动物科技学院·动物医学院动物健康互联网检测技术浙江省工程研究中心浙江省动物医学与健康管理国际科技合作基地浙江省畜禽绿色生态健康养殖应用技术研究重点实验室中澳动物健康大数据分析联合实验室浙江杭州311300

铁、铜、锌、锰等金属离子是各类生物体生存和增殖所必需的微量元素,可影响生物体内蛋白酶活性、免疫反应、生理过程和抗感染机制。细菌感染过程中,宿主可通过限制或提高体内环境中金属离子的浓度来抑制细菌增殖,与此同时,细菌进化出各... 详细信息

铁、铜、锌、锰等金属离子是各类生物体生存和增殖所必需的微量元素,可影响生物体内蛋白酶活性、免疫反应、生理过程和抗感染机制。细菌感染过程中,宿主可通过限制或提高体内环境中金属离子的浓度来抑制细菌增殖,与此同时,细菌进化出各种转运系统以适应宿主体内金属离子水平的变化。由于不同细菌的金属离子外排系统在结构和生化特性上存在变异,它们呈现出独特的金属离子外排模式。本文根据现有文献报道及本团队研究结果,对铁、铜、锌和锰离子的细菌外排系统进行讨论和总结,旨在综述目前对细菌金属离子稳态调控机制研究进展的认识,为深入理解细菌金属稳态调控相关机制提供参考。

关键词：金属离子外排系统细菌感染金属离子稳态调控机制

L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons

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Neuroscience Bulletin 2024年第7期40卷 921-936页

作者： Wen-Yong Fan Yi-Ming Chen Yi-Fan Wang Yu-Qi Wang Jia-Qi Hu Wen-xu Tang Yi Feng Qian Cheng Lei xue State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433China Department of Physiology and Neurobiology School of Life SciencesFudan UniversityShanghai 200438China Institute of Acoustics School of Physics Science and EngineeringTongji UniversityShanghai 200092China Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education Tongji UniversityShanghai 200070China Center for Rehabilitation Medicine Department of Pain ManagementZhejiang Provincial People's HospitalAffliated People's HospitalHangzhou Medical CollegeHangzhou 310014China Department of Critical Care Medicine Shanghai General HospitalShanghai Jiaotong University School of MedicineShanghai 200080China Shanghai Research Institute for Intelligent Autonomous Systems Tongji UniversityShanghai 201210China Research Institute of Intelligent Complex Systems Fudan UniversityShanghai 200433China

As a noninvasive technique,ultrasound stimulation is known to modulate neuronal activity both in vitro and in *** latest explanation of this phenomenon is that the acoustic wave can activate the ion channels and further impact the electrophysiological properties of targeted ***,the underlying mechanism of low-intensity pulsed ultrasound(LIPUS)-induced neuro-modulation effects is still ***,we characterize the excitatory effects of LIPUS on spontaneous activity and the intracellular Ca^(2+)homeostasis in cultured hippocampal *** whole-cell patch clamp recording,we found that 15 min of 1-MHz LIPUS boosts the frequency of both spontaneous action potentials and spontaneous excitatory synaptic currents(sEPSCs)and also increases the amplitude of sEPSCs in hippocampal *** phenomenon lasts for>10 min after LIPUS *** with Ca^(2+)imaging,we clarified that LIPUS increases the[Ca^(2+)]cyto level by facilitating L-type Ca^(2+)channels(LTCCs).In addition,due to the[Ca^(2+)]cyto elevation by LIPUS exposure,the Ca^(2+)-dependent CaMKII-CREB pathway can be activated within 30 min to further regulate the gene transcription and protein *** work suggests that LIPUS regulates neuronal activity in a Ca^(2+)-dependent manner via *** may also explain the multi-activation effects of LIPUS beyond *** stimulation potentiates spontaneous neuronal activity by increasing Ca^(2+)influx.

关键词： Low-intensity pulsed ultrasound Neuromodulation L-type calcium channel Hippocampal neuron

Practical Experience of Management of Urban Parks at Home and Abroad

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Meteorological and Environmental Research 2024年第1期15卷 30-37页

作者： Wenqian LING Yong ZHU Qinhuai xu Chengdu Institute of Planning&Design Chengdu 610061China

By systematically reviewing the practical experience of management of urban parks at home and abroad,the advanced experience in organization,management system,operation mechanism and social participation were summarized,and the optimization and improvement measures for the construction and management of urban parks in Chengdu were proposed to provide reference for the high-level construction,high-quality experience and efficient management of urban parks in the construction of park city demonstration zone in Chengdu.

关键词： Urban parks Management and operation Domestic and foreign experience Chengdu Park city

回归史料本身——图像证史问题的档案学思考路径及其反思

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云南大学学报（社会科学版） 2024年第3期23卷 56-65页

作者：杨毅单旭东云南大学昆明650091

图像证史问题既是传统艺术史领域的重要议题,也是图像研究进入历史学领域的重要前提。图像虽已作为新的史料依据和证据来源进入历史学实践,但图像资料在“可信度”与“清晰度”上的困境,以及其作为文字叙述补充的附属地位影响其入史的... 详细信息

图像证史问题既是传统艺术史领域的重要议题,也是图像研究进入历史学领域的重要前提。图像虽已作为新的史料依据和证据来源进入历史学实践,但图像资料在“可信度”与“清晰度”上的困境,以及其作为文字叙述补充的附属地位影响其入史的限度与可能性,引发历史学理论层面对于史料观念的思考。此番问题的讨论究其根源在于当前史学领域虽在应用领域关注图像史料,但是仍旧未能脱离文字史料研究的路径惯性,因此也就未能对图像自身特殊的记录方式及其所决定的多元内容信息予以理论视角的明晰。以档案学视角重新审视图像证史的问题本质与作用机制,借图像资料本身的档案属性与史料特质,图像得以进入历史研究的视野进而成为客观、原始的文本依据,继而完成图像入史的研究前提;而要真正实现图像证史的目的,则要全面的认识图像的内容构成及其所对应的历史联系,以更为详细、全面的文献记载还原更为复杂、多面的历史事实。所以图像证史问题的讨论要回归图像史料的记录特性本身,在史料的求真、求新之外更要求全,在实现完整、系统的史料观念认知与运用的同时,也为更多的相关问题提供思路与方法借鉴。

关键词：图像证史二元档案实践史料观

The Application of Analytic Hierarchy Process Method in the Evaluation of Educational Quality in Colleges and Universities

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Journal of Contemporary Educational Research 2024年第7期8卷 335-342页

作者： Junbo Lei Yanxia xu Junpeng Wang School of Foreign Languages Heilongjiang University of Business and TechnologyHarbin 150025Heilongjiang ProvinceChina School of Foreign Language Harbin Cambridge UniversityHarbin 150086Heilongjiang ProvinceChina English Department Heilongjiang International UniversityHarbin 150500Heilongjiang ProvinceChina

Talent quality is the lifeline of colleges and *** on employment guidance,this paper establishes a student quality evaluation and control system including knowledge,moral character,and ability,and uses the Analytic Hierarchy Process(AHP)method to analyze the factors affecting the quality of education in colleges and *** addition,some suggestions are provided to improve the quality of students.

关键词： Student quality Knowledge Ability Literacy

基于模糊数学与响应面法对黑蒜茶树菇酱加工工艺进行优化

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中国调味品 2024年第1期49卷 119-123页

作者：吴英迪徐国东范太行南阳科技职业学院河南邓州474150 南阳师范学院河南南阳473000 河南财经政法大学郑州450003

酱体是生活中最常见的调味品,常用于烹饪和调味,是生活中不可或缺的调味料。该研究以茶树菇和黑蒜为材料,以感官评分为指标,通过单因素试验、模糊数学评价和正交试验研究淀粉添加量、食盐添加量、植物油添加量、葱、姜、蒜添加量和白砂... 详细信息

酱体是生活中最常见的调味品,常用于烹饪和调味,是生活中不可或缺的调味料。该研究以茶树菇和黑蒜为材料,以感官评分为指标,通过单因素试验、模糊数学评价和正交试验研究淀粉添加量、食盐添加量、植物油添加量、葱、姜、蒜添加量和白砂糖添加量对黑蒜茶树菇酱加工工艺的影响。研究结果表明,黑蒜茶树菇酱的最佳加工工艺为淀粉添加量1.0%、食盐添加量2.0%、植物油添加量6.0%、葱、姜、蒜添加量0.8%和白砂糖添加量1.0%,此时黑蒜茶树菇酱的感官评分为86.56分,该条件下加工的黑蒜茶树菇酱香气醇厚,色泽光鲜,黏稠度适中。

关键词：酱体黑蒜茶树菇模糊数学正交试验

Research Progress of Seafloor Pockmarks in Spatio-Temporal Distribution and Classification

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Journal of Ocean University of China 2020年第1期19卷 69-80页

作者： xu Cuiling xu Guoqiang xing Junhui SUN Zhilei WU Nengyou Key Laboratory of Gas Hydrate Qingdao Institute of Marine GeologyMinistry of Natural ResourcesQingdao 266071China Laboratory for Marine Mineral Resources Qingdao National Laboratory for Marine Science and TechnologyQingdao 266071China College of Marine Geosciences/Key Laboratory of Submarine Geosciences and Prospecting Techniques Ministry of EducationQingdao 266100China The First Institute of Oceanography Ministry of Natural ResourcesQingdao 266071China

Seafloor pockmarks are important indicators of submarine methane seepages and slope *** order to promote the understanding of submarine pockmarks and their relationship with sediment instabilities and climate changes,here we summarize the research results of pockmarks in the spatio-temporal distributions and shaping *** of pockmarks occur along active or passive continental margins during the last 25 kyr B.P..Circular and ellipse are the most common forms of pockmarks,whereas pockmarks in a special crescent or elongated shape are indicators of slope instabilities,and ring-shape pockmarks are endemic to the gas hydrate *** researches should be focused on the trigger mechanism of climate changes based on the pockmarks in the high latitudes formed during the deglaciation periods,and the role of gas hydrates in the seafloor evolution should be *** addition,the feature of pockmarks at their early stage(e.g.,developing gas chimneys and gas driving sedimentary doming)and the relations between pockmarks and mass movements,mud diapirs could be further studied to clarify the influences of rapid methane release from submarine sediments on the atmospheric carbon contents.

关键词： pockmark cold seep methane seepage gas hydrate slump

Artiﬁcial intelligence in tunnel construction: A comprehensive review ofhotspots and frontier topics

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Geohazard Mechanics 2024年第1期2卷 1-12页

作者： Lianbaichao Liu Zhanping Song xu Li School of Civil Engineering Xi'an University of Architecture and TechnologyXi'an710055China Shaanxi Key Lab of Geotechnical and Underground Space Engineering Xi'an710055China Institute of Tunnel and Underground Structure Xi'an University of Architecture and TechnologyXi'an710055China

Application of Artiﬁcial Intelligence(AI)in tunnel construction has the potential to transform the industry by improving efﬁciency,safety,and *** paper presents a comprehensive literature review and analysis of hotspots and frontier topics in artiﬁcial intelligence-related research in tunnel construction.A total of 554 articles published between 2011 and 2023 were collected from the Web of Science(WOS)core collection database and analyzed using CiteSpace *** analysis identiﬁed three main study areas:Tunnel Boring Machine(TBM)performance,construction optimization,and rock and soil *** review highlights the advancements made in each area,focusing on design and operation,performance prediction models,and fault detection in TBM performance;computer vision and image processing,neural network algorithms,and optimization and decision-making in construction optimization;and geo-properties and behaviours,tunnel stability and excavation,and risk assessment and safety management in rock and soil *** paper concludes by discussing future research directions,emphasizing the integration of AI with other advanced technologies,realtime decision-making systems,and the management of environmental impacts in tunnel *** comprehensive review provides valuable insights into the current state of AI research in tunnel engineering and serves as a reference for future studies in this rapidly evolvingﬁeld.

关键词： Literature review Underground construction CiteSpace Artiﬁcial intelligent Bibliometrics analysis

OsWRKY78 regulates panicle exsertion via gibberellin signaling pathway in rice

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Journal of Integrative Plant Biology 2024年第4期66卷 771-786页

作者： Enyang Mei Mingliang He Min xu Jiaqi Tang Jiali Liu Yingxiang Liu Zhipeng Hong Xiufeng Li Zhenyu Wang Qingjie Guan Xiaojie Tian Qingyun Bu State Key Laboratory of Black Soils Conservation and Utilization Key Laboratory of Soybean Molecular Design BreedingNortheast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Saline-alkali Vegetation Ecology Restoration Northeast Forestry UniversityMinistry of EducationHarbin 150040China College of Life Science Northeast Forestry UniversityHarbin 150040China

Panicle exsertion is one of the crucial agronomic traits in rice(Oryza sativa).Shortening of panicle exsertion often leads to panicle enclosure and severely reduces seed ***(GA)plays important roles in regulating panicle ***,the underlying mechanism and the relative regulatory network remain ***,we characterized the oswrky78 mutant showing severe panicle enclosure,and found that the defect of oswrky78 is caused by decreased bioactive GA *** analysis demonstrates that OsWRKY78 can directly activate GA biosynthesis and indirectly suppress GA ***,we found OsWRKY78 can interact with and be phosphorylated by mitogen-activated protein kinase(MAPK)kinase OsMAPK6,and this phosphorylation can enhance OsWRKY78 stability and is necessary for its biological *** together,these results not only reveal the critical function of OsWRKY78,but also reveal its mechanism via mediating crosstalk between MAPK and the GA signaling pathway in regulating panicle exsertion.

关键词： gibberellin MAPK cascades OsWRKY78 panicle exsertion rice