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Experience of Clinical Management for Pregnant Women and Newborns with Novel Coronavirus Pneumonia in Tongji Hospital,China

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Current Medical Science 2020年第2期40卷 285-289页

作者： Shao-shuai wanG Xuan ZHOU xing-guang LIN Yan-yan LIU Jian-li WU Lali Mwamaka Shariful Xiao-lin HU Zhi-bui RONG Wei LIU Xiao-ping LUO zhuo chen wan-jiang ZENG Su-hua chen Ding MA Ling chen Ling FENG Department of Obstetrics and Gynecology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Pediatrics Tongji HospitalTongji Medical CollegeHuazhong Universiry 0f Science and TechnologyWuhan 430030 China Deparment of Traditional Chinese Medicine Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

Based on the New Diagnosis and Treatment Scheme for Novel Coronavirus Infected Pneumonia(Trial Edition 5),combined with our current clinical treatment experience,we recently proposed a revision of the first edition of“Guidance for maternal and fctal management during pneumonia epidemics of novel coronavirus infection in the Wuhan Tongji Hospital".This article focused on the issues of greatest concern of pregnant women including severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection diagnostic criteria,inspection precautions,drug treatment options,indications and methods of termination of pregnancy,postpartum fever,breastfeeding considerations,mode of mother-to-child transmission,neonatal isolation and advice on nconatal nursing,to provide valuable experience for better management of SARS-CoV-2 infection in pregnant women and newborns.

关键词： COVID-19 pneumonia pregnant women newborn disease management

闪速吹炼炉内颗粒在不同操作参数下的分布与演化规律

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中国有色金属学报:英文版 2023年第9期33卷 2866-2878页

作者：祝振宇周萍陈卓周俊万兴邦张劲松任鹏中南大学能源科学与工程学院长沙410083 铜陵有色金属集团控股有限公司铜陵244000

通过开展工业试验揭示闪速吹炼炉内颗粒质量和粒径的分布与演化规律,同时研究不同配风参数对颗粒分布的影响。结果表明,颗粒在反应塔内的下落过程中,其平均粒径增长通常为2~3倍,且聚并后的大颗粒主要分布在料锥中部和外部;而导致该现象... 详细信息

通过开展工业试验揭示闪速吹炼炉内颗粒质量和粒径的分布与演化规律,同时研究不同配风参数对颗粒分布的影响。结果表明,颗粒在反应塔内的下落过程中,其平均粒径增长通常为2~3倍,且聚并后的大颗粒主要分布在料锥中部和外部;而导致该现象出现的原因是较高的湍流强度和颗粒分布密度、以及天然气燃烧的位置使该位置处颗粒升温熔融、并发生碰撞和聚并。另外,提高分散风与工艺风动量比能使物料颗粒在反应塔内的分布更加均匀,更有利于冰铜的氧化反应。相较于调整工艺风参数,改变分散风能更有效地提高颗粒的空间分布范围。

关键词：工业试验颗粒演化质量分布粒径分布动量比闪速吹炼炉

Wikstroelide M potently inhibits HIV replication by targeting reverse transcriptase and integrase nuclear translocation

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Chinese Journal of Natural Medicines 2014年第3期12卷 186-193页

作者： ZHANG Xuan HUANG Sheng-zhuo GU wan-Gang YANG Liu-Meng chen Huan ZHENG Chang-Bo ZHAO You-xing wan David Chi-Cheong ZHENG Yong-Tang Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences&Yunnan Province KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common DiseasesKunming Institute of ZoologyChinese Academy of Sciences School of Pharmaceutical Science&Yunnan Key Laboratory of Pharmacology for Natural Products Kunming Medical University Institute of Tropical Bioscience and Biotechnology Chinese Academy of Tropical Agricultural Sciences School of Biomedical Sciences KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common DiseasesFaculty of MedicineThe Chinese University of Hong Kong School of Pharmacy China Pharmaceutical University

AIM： To evaluate the anti-HIV activity and mechanism of action of wikstroelide M, a daphnane diterpene from Daphne acutiloba Rehder （Thymelaeaceae）. METHOD： The anti-HIV activities of wikstroelide M against different HIV strains were evaluated by cytopathic effect assay and p24 quantification assay with ELISA. The inhibitory effect of wikstroelide M on HIV reverse transcription was analyzed by real-time PCR and ELISA. The effect of wikstroelide M on HIV-1 integrase nuclear translocation was observed with a cell-based imaging assay. The effect of wikstroelide M on LEDGF/p75-IN interaction was assayed by molecular docking. RESULTS： Wikstroelide M potently inhibited different HIV-1 strains, including HIV-lmn, HIV-1AI7, and HIV-19495, induced a cytopathic effect, with ECs0 values ranging from 3.81 to 15.65 ***-I. Wikstroelide M also had high inhibitory activities against HIV-2noD and HIV-2cBL_20-induced cytopathic effects with ECs0 values of 18.88 and 31.90 *** 1. The inhibitory activities of wikstroelide M on the three HIV-1 strains were further confirmed by p24 quantification assay, with ECs0 values ranging from 15.16 to 35.57 ***-1. Wikstroelide M also potently inhibited HIV-lnm induced cytolysis in MT-4 cells, with an ECs0 value of 9.60 *** ~. The mechanistic assay showed that wikstroelide M targeted HIV-I reverse transcriptase and nuclear translocation of integrase through disrupting the interaction between integrase and LEDGF/p75. CONCLUSION： Wikslroelide M may be a potent HIV-1 and HIV-2 inhibitor, the mechanisms of action may include inhibition of reverse trascriptase activity and inhibition of integrase nuclear Iranslocation through dismpting the interaction between integrase and LEDGF/p75.

关键词： Wikstroelide M Daphnane diterpene Daphne acutiloba Rehder HIV Reverse trascriptase integrase Nucleartranslocation Lens epithelium-derived growth factor (LEDGF/p75) Molecular docking

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兰州-西宁城市群人口集聚格局及影响因素

兰州大学学报（自然科学版） 2019年第4期55卷 436-442页

作者：贾卓陈兴鹏李晨曦马振邦兰州大学资源环境学院

以中国西部兰州-西宁城市群为研究区,分析人口集聚格局和影响人口集聚的因素.结果表明:兰州-西宁城市群人口集聚具有'中心-外围'特征和'马太效应'.兰州-西宁城市群人口集聚的空间依赖性不断增强,兰州市和西宁市所辖核心县(区)为人口集... 详细信息

以中国西部兰州-西宁城市群为研究区,分析人口集聚格局和影响人口集聚的因素.结果表明:兰州-西宁城市群人口集聚具有'中心-外围'特征和'马太效应'.兰州-西宁城市群人口集聚的空间依赖性不断增强,兰州市和西宁市所辖核心县(区)为人口集聚热点区,白银市、定西市、临夏州和海东市所辖欠发达县(区)为人口集聚冷点区.兰州-西宁城市群人口集聚存在空间溢出效应,地区生产总值和专任教师数对人口集聚具有显著促进作用;年平均温度、第二产业占地区生产总值比重、第三产业占地区生产总值比重和公共预算支出对人口集聚具有一定促进作用;年平均降水量和固定资产投资额对人口集聚的影响未通过显著性检验.

关键词：人口集聚空间效应影响因素空间计量模型兰州-西宁城市群

Clinical practice guideline for transurethral plasmakinetic resection of prostate for benign prostatic hyperplasia(2021 Edition)

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Military Medical Research 2022年第5期9卷 515-533页

作者： Xian-Tao Zeng Ying-Hui Jin Tong-Zu Liu Fang-Ming chen De-Gang Ding Meng Fu Xin-Quan Gu bang-Min Han xing Huang Zhi Hou wan-Li Hu Xin-Li Kang Gong-Hui Li Jian-xing Li Pei-Jun Li Chao-Zhao Liang Xiu-Heng Liu Zhi-Yu Liu Chun-Xiao Liu Jiu-Min Liu Guang-Heng Luo Yi Luo Wei-Jun Qin Jian-Hong Qiu Jian-Xin Qiu Xue-Jun Shang Ben-Kang Shi Fa Sun Guo-Xiang Tian Ye Tian Feng wang Feng wang Yin-Huai wang Yu-Jie wang Zhi-Ping wang Zhong wang Qiang Wei Min-Hui Xiao wan-Hai Xu Fa-Xian Yi Chao-Yang Zhu Qian-Yuan Zhuang Li-Qun Zhou Xiao-Feng Zou Nian-Zeng xing Da-Lin He xing-Huan wang 无 Department of Urology Institute of UrologyZhongnan Hospital of Wuhan UniversityWuhan430071China Center for Evidence-Based and Translational Medicine Zhongnan Hospital of Wuhan UniversityWuhan430071China Department of Urology Tianjin Third Central Hospital Affiliated To Nankai UniversityTianjin300170China Department of Urology Henan Provincial People’s HospitalZhengzhou University People’s HospitalZhengzhou450003China Department of Urology Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China Department of Urology China-Japan Union Hospital of Jilin UniversityChangchun130033China Department of Urology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai200080China Department of Urology Qinghai University Affiliated HospitalXi’ning810012China Department of Urology People’s Hospital of Hainan ProvinceHainan Affiliated Hospital of Hainan Medical University HaikouHaikou570311China Department of Urology Sir Run Run Shaw HospitalZhejiang University School of MedicineHangzhou310016China Department of Urology General Hospital of Ningxia Medical UniversityYinchuan750003China Department of Urology The First Affiliated Hospital of Anhui Medical UniversityHefei230022China Department of Urology Renmin Hospital of Wuhan UniversityWuhan430060China Department of Urology The Second Hospital of Dalian Medical UniversityDalian116023LiaoningChina Department of Urology Zhujiang Hospital of Southern Medical UniversityGuangzhou510282China Department of Urology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou510080China Department of Urology Surgery Guizhou Province People’s HospitalGuiyang550002China Department of Urology Xijing Hospital of Air Force Military Medical UniversityXi’an710032China Department of Urology The 980St Hospital of the PLA Joint Logistics Support Force(Bethune International Peace Hospital of PLA)Shijiazhuang050082China Department of Urology

Benign prostatic hyperplasia (BPH) is highly prevalent among older men, impacting on their quality of life, sexual function, and genitourinary health, and has become an important global burden of disease. Transurethral plasmakinetic resection of prostate (TUPKP) is one of the foremost surgical procedures for the treatment of BPH. It has become well established in clinical practice with good efficacy and safety. In 2018, we issued the guideline “2018 Standard Edition”. However much new direct evidence has now emerged and this may change some of previous recommendations. The time is ripe to develop new evidence-based guidelines, so we formed a working group of clinical experts and methodologists. The steering group members posed 31 questions relevant to the management of TUPKP for BPH covering the following areas: questions relevant to the perioperative period (preoperative, intraoperative, and postoperative) of TUPKP in the treatment of BPH, postoperative complications and the level of surgeons’ surgical skill. We searched the literature for direct evidence on the management of TUPKP for BPH, and assessed its certainty generated recommendations using the grade criteria by the European Association of Urology. Recommendations were either strong or weak, or in the form of an ungraded consensus-based statement. Finally, we issued 36 statements. Among them, 23 carried strong recommendations, and 13 carried weak recommendations for the stated procedure. They covered questions relevant to the aforementioned three areas. The preoperative period for TUPKP in the treatment of BPH included indications and contraindications for TUPKP, precautions for preoperative preparation in patients with renal impairment and urinary tract infection due to urinary retention, and preoperative prophylactic use of antibiotics. Questions relevant to the intraoperative period incorporated surgical operation techniques and prevention and management of bladder explosion. The application to different

关键词： Transurethral plasmakinetic resection of prostate Benign prostatic hyperplasia Recommendation Treatment Guideline

中国西部兰白西城市群经济增长结构分解及空间特征

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干旱区地理 2018年第5期41卷 1106-1114页

作者：贾卓陈兴鹏马振邦强文丽李恩龙兰州大学资源环境学院甘肃兰州730000 兰州大学资源环境学院中国西部循环经济研究中心甘肃兰州730000 兰州大学西部环境教育部重点实验室甘肃兰州730000

采用偏离—份额四分量模型,分解2010—2015年兰白西城市群41个县(区)经济增长结构;采用空间数据分析方法,分析41个县(区)经济增长总量及各分量空间特征。结果表明:(1)兰白西城市群呈现以兰州市和西宁市为双核心的"中心—外围"经济结构,... 详细信息

采用偏离—份额四分量模型,分解2010—2015年兰白西城市群41个县(区)经济增长结构;采用空间数据分析方法,分析41个县(区)经济增长总量及各分量空间特征。结果表明:(1)兰白西城市群呈现以兰州市和西宁市为双核心的"中心—外围"经济结构,兰州市的经济中心地位更为显著。(2)根据经济增长总量及各分量,将兰白西城市群41个县(区)分为经济快速增长型、经济滞后增长型、竞争力优势推动型和资源配置优势推动型等4种类型。(3)经济增长总量、份额偏离分量、产业结构分量在空间上存在集聚性特征,竞争力分量在空间上存在随机分布性特征,资源配置分量在空间上存在负相关性特征。(4)份额偏离分量、产业结构分量与经济增长总量的空间重合度较高,竞争力分量、资源配置分量与经济增长总量的空间重合度有待优化。

关键词：兰白西城市群县域经济偏离一份额四分量模型空间数据分析空间特征

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin chen Danping chen Fuqing chen Fusan chen Gang chen Guoming chen Hua-xing chen Huirun chen Jinhui chen Ji-Yuan chen Kai chen Mali chen Mingjun chen Mingshui chen Ning chen Shanhong chen Shanzhen chen Shao-Long chen Shaomin chen Shiqiang chen Tianlu chen Wei chen Xiang chen Xiaoyu chen Xin chen Xun chen Xurong chen Ye chen Ying chen Yukai chen Zelin chen Zilin chen Gang chen Boping chen Chunhui chen Hok Chuen cheng Huajie cheng Shan cheng Tongguang cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker Institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China Institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear Instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

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基于单周控制的有源功率因数校正电路设计

电力电子技术 2006年第4期40卷 89-90,119页

作者：陈延明杨兴龙万忠东陈卓毅广西大学广西南宁530004 广西武鸣电业公司广西南宁530100

采用基于单周控制的专用芯片IR1150[2],设计了一台1kW的功率因数校正装置。文中介绍了基于单周控制的单相有源功率因数校正电路的基本原理,给出了以IR1150为核心的单相有源功率因数校正装置的设计方法。实验结果表明,该装置具有结构简... 详细信息

采用基于单周控制的专用芯片IR1150[2],设计了一台1kW的功率因数校正装置。文中介绍了基于单周控制的单相有源功率因数校正电路的基本原理,给出了以IR1150为核心的单相有源功率因数校正装置的设计方法。实验结果表明,该装置具有结构简单、抗干扰性强、响应速度快等特点。

关键词：功率因数控制/峰值电流

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高速逆流色谱法分离珠子草中的木脂素

广西大学学报（自然科学版） 2014年第5期39卷 1191-1197页

作者：陈剑莫银屏胡吉卓刘志平韦万兴广西大学化学化工学院广西南宁530004

为克服采用传统方法分离木脂素的不足,采用高速逆流色谱法对珠子草中的木脂素进行分离,得到3个木脂素,通过红外光谱(IR)、质谱(MS)、核磁共振(NMR)等方法鉴定为珠子草素(niranthin)、叶下珠次素(hypophyllanthin)和叶下珠脂素(phyllanth... 详细信息

为克服采用传统方法分离木脂素的不足,采用高速逆流色谱法对珠子草中的木脂素进行分离,得到3个木脂素,通过红外光谱(IR)、质谱(MS)、核磁共振(NMR)等方法鉴定为珠子草素(niranthin)、叶下珠次素(hypophyllanthin)和叶下珠脂素(phyllanthin)。分离溶剂体系为正己烷/乙酸乙酯/甲醇/水(3/2/3/2,V/V),下相为流动相,流速为2 mL/min,转速为正转800 r/min,温度为25℃。实验结果为木脂素的分离提供了一条有效的途径。

关键词：珠子草木脂素分离高速逆流色谱