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Ultrahigh spatiotemporal resolution beam signal reconstruction with bunch phase compensation

Nuclear Science and Techniques 2024年第5期35卷 99-108页

作者： You-Ming Deng Yong-Bin Leng xing-yi xu Jian Chen yi-Mei Zhou Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of the Chinese Academy of Sciences Beijing 100049China Shanghai Synchrotron Radiation Facility Chinese Academy of SciencesShanghai 201204China University of Science and Technology of China Hefei 230026China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China

Various electromagnetic signals are excited by the beam in the acceleration and beam-diagnostic elements of a particle *** is important to obtain time-domain waveforms of these signals with high temporal resolution for research,such as the study of beam–cavity interactions and bunch-by-bunch parameter ***,a signal reconstruction algorithm with ultrahigh spatiotemporal resolution and bunch phase compensation based on equivalent sampling is proposed in this *** with traditional equivalent sampling,the use of phase compensation and setting the bunch signal zero-crossing point as the time reference can construct a more accurate reconstructed *** basic principles of the method,simulation,and experimental comparison are also *** on the beam test platform of the Shanghai Synchrotron Radiation Facility(SSRF)and the method of experimental verification,the factors that affect the reconstructed signal quality are analyzed and discussed,including the depth of the sampled data,quantization noise of analog-to-digital converter,beam transverse oscillation,and longitudinal *** results of the beam experiments show that under the user operation conditions of the SSRF,a beam excitation signal with an amplitude uncertainty of 2%can be reconstructed.

关键词： Turn-by-turn bunch phase compensation technique Equivalent sampling Signal reconstruction algorithm Ultrahigh spatiotemporal resolution SSRF

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HOTCAP:a new software package for high-speed oscilloscopebased three-dimensional bunch charge and position measurement

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Nuclear Science and Techniques 2021年第11期32卷 163-173页

作者： xing-yi xu Yong-Bin Leng Bo Gao yi-Mei Zhou Shan-Shan Cao Jian Chen Fang-Zhou Chen Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China

A software package to be used in high-speed oscilloscope-basedthree-dimensionalbunch-by-bunch charge and position measurement is *** software package takes the pick-up electrode signal waveform recorded by the high-speed oscilloscope as input,and it calculates and outputs the bunch-by-bunch charge and *** addition to enabling a three-dimensional observation of the motion of each passing bunch on all beam position monitor pick-up electrodes,it offers many additional features such as injection analysis,bunch response function reconstruction,and turn-by-turn beam *** software package has an easy-to-understand graphical user interface and convenient interactive operation,which has been verified on the Windows 10 system.

关键词： Bunch-by-bunch measurement HOTCAP software package Data analysis High-speed oscilloscope

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Touschek lifetime study based on the precise bunch-by-bunch BCM system at SSRF

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Nuclear Science and Techniques 2019年第9期30卷 126-133页

作者： Fang-Zhou Chen Zhi-Chu Chen yi-Mei Zhou Ning Zhang Bo Gao xing-yi xu Yong-Bin Leng Shanghai Institute of Applied Physics Chinese Academy of Sciences Shanghai 201800 China University of Chinese Academy of Sciences Beijing 100049 China Shanghai Advanced Research Institute Chinese Academy of Sciences Shanghai 201200 China

Continuous tracking of bunch charges is the key to maintain stable operations in a storage ring in top-up mode. Recently, a precise bunch-by-bunch beam-current measurement (BCM) system has been developed at the Shanghai Synchrotron Radiation Facility. To avoid the influence of longitudinal oscillation on the amplitudes of the sampling points, a method called two-point equilibrium sampling is introduced. The results, obtained during routine operation time, show that the relative resolution of the measurement of the bunch charges is better than 0.02%. With this high resolution, the new BCM system is able to monitor the bunch-by-bunch beam lifetime. By using the filling pattern information, the Touschek lifetime and the vacuum lifetime can also be calculated. In this paper, the principle of the new method and the experiments is presented in detail.

关键词： Beam-current measurement Bunch-bybunch Touschek lifetime Vacuum lifetime SSRF

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In vivo study of extracellular matrix coating enhancing fixation of the pedicle screw-bone＇s interface

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Chinese Medical Journal 2011年第23期124卷 3945-3952页

作者： LIU Guo-min ZHANG xing-yi xu Chuan-jie ZHU Xiao-min WANG Jun LIU yi Department of Ortiaopedics Department of Thoracic Surgery Changchun Jilin 130041 China

Based on in vivo research on the effect of the coating of the extracellular matrix composition of pedicle screws on the conduction and induction of bone formation in young sheep, the aim of this study was to investigate the application of coated pedicle screws in sheep with scoliosis whose spines are under constant development. Methods Four groups of pedicle screws were randomly implanted into bilateral L2-L5 pedicles of 2.5- to 3-month-old sheep. A static experiment was performed on one side and a loading test was performed on the other side by implanting connecting rods at the L2-L3 and L4-L5 segments. The changes in the force on the coated screws and the combination of the surface of the coated screws with the surrounding bone in the growth process of young sheep＇s spines with aging were observed. After 3 months, the lumbar vertebrae with the screws were removed and examined by micro-CT, histological, and biomechanical analyses. Results Under nonloading conditions, there is bone formation around the surfaces of coated screws. The bone forming on the surface of collagen/chondroitin sulfate/hydroxyapatite coating of pedicle screws is the most, the one of the collagen / chondroitin sulfate coating and hydroxyapatite coating is followed, and no significant difference between the two groups. In terms of the trabecular bone morphology parameters of the region of interest around the surface of the pedicle screws, such as bone mineral content, bone mineral density, tissue mineral content, tissue bone mineral density, bone volume fraction, and connection density, those associated with collagen/chondroitin sulfate/hydroxyapatite coatings are largest and those unassociated with coatings are smallest. Under nonloading conditions, the pullout strength of the collagen/chondroitin sulfate/hydroxyapatite-coated screws was largest, and that of the uncoated screws was minimal （P 〈0.01）. Under loading conditions, the maximum pullout strength of each group of pedicle screws was less

关键词： hydroxyapatite collagen chondroitin sulfate micro-CT biomechanics

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Nonlinear dynamics of electroencephalography study in schizophrenic patients

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Chinese Medical Journal 2013年第15期126卷 2886-2889页

作者： CHEN xing-shi xu yi-feng TANG Yun-xiang FANG yi-ru ZHANG Chen ZHANG Ming-dao LOU Fei-ying LIANG Jian-hua CHEN Chong PAN Xiao YAN Jin CUI yi Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Dept Electrophysiol Shanghai 200030 Peoples R China Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Dept Psychiat Shanghai 200030 Peoples R China PLA Mil Med Univ 2 Fac Psychol & Mental Hlth Shanghai 200433 Peoples R China

Background Few characteristic changes of linear electroencephalograph （EEG） have been reported in schizophrenia. The aim of the present study was to investigate the changes in temporal-spatial dimensional properties of EEG under different cognitive tasks in patients with schizophrenia. Methods EEG was recorded by using EEG-1518K system and mapping system （Nihon Kohden Tomioka Corporation, Japan） in 45 schizophrenic patients and 47 healthy adults （normal control, NC） under five states： eyes c^osed, eyes open, mental arithmetic test with eyes closed, memory test with eyes open, and number cancellation test. Correlation dimension （D2） and point-wise correlation dimension （PD2） were calculated for all EEG analyses. Results （1） There were no significant differences of D2 and PD2 between NC and schizophrenic patients under states of eyes open and closed. （2） Compared with NC, schizophrenic patients showed decreased performance of D2 in mental arithmetic test with eyes closed and number cancellation test （mental arithmetic test with eyes closed： Nc 5.9±0.6, Sch 3.0＋0.8; number cancellation test： Nc 6.0±0.6, Sch 4.4±0.7; P 〈0.05 or P 〈0.01）. （3） Schizophrenic patients also showed decrease performance of PD2 in mental arithmetic test with eyes closed, memory test with eyes open, and number cancellation test （mental arithmetic test with eyes closed： Nc 6.9±0.7, Sch 4.0±0.8; memory test with eyes open： Nc 6.6±0.8, Sch 5.0±0.9; number cancellation test： Nc 7.1±0.7, Sch 4.8±0.9; P 〈0.05 or P 〈0.01）. Conclusions Nonlinear dynamic analysis provided a new approach in clinical investigation of EEG signals. It was helpful to further understand the cerebral mechanism in schizophrenic cognitive process.

关键词： schizophrenia electroencephalography nonlinear dynamics cognition

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Recent Advances in Fibrous Materials for Hydroelectricity Generation

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Nano-Micro Letters 2025年第2期17卷 109-133页

作者： Can Ge Duo xu Xiao Feng xing Yang Zheheng Song Yuhang Song Jingyu Chen yingcun Liu Chong Gao Yong Du Zhe Sun Weilin xu Jian Fang College of Textile and Clothing Engineering Soochow UniversitySuzhou 215123People’s Republic of China National Engineering Laboratory for Modern Silk Soochow UniversitySuzhou 215123People’s Republic of China State Key Laboratory of New Textile Materials and Advanced Processing Technologies Wuhan Textile UniversityWuhan 430200People’s Republic of China Institute of Functional Nano&Soft Materials(FUNSOM) Soochow UniversitySuzhou 215123People’s Republic of China Department of Electrical and Computer Engineering University of MassachusettsAmherstMA 01003USA Department of Materials Imperial College LondonSouth Kensington CampusLondon SW72AZUK College of Textile Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China School of Materials Science and Engineering Shanghai Institute of Technology100 Haiquan RoadShanghai 201418People’s Republic of China

Depleting fossil energy sources and conventional polluting power generation pose a threat to sustainable *** generation from ubiquitous and spontaneous phase transitions between liquid and gaseous water has been considered a promising strategy for mitigating the energy *** materials with unique flexibility,processability,multifunctionality,and practicability have been widely applied for fibrous materials-based hydroelectricity generation(FHG).In this review,the power generation mechanisms,design principles,and electricity enhancement factors of FHG are first ***,the fabrication strategies and characteristics of varied constructions including 1D fiber,1D yarn,2D fabric,2D membrane,3D fibrous framework,and 3D fibrous gel are ***,the advanced functions of FHG during water harvesting,proton dissociation,ion separation,and charge accumulation processes are analyzed in ***,the potential applications including power supply,energy storage,electrical sensor,and information expression are also ***,some existing challenges are considered and prospects for future development are sincerely proposed.

关键词： Hydroelectricity Fibrous material Streaming potential Ion diffusion

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Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

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Neural Regeneration Research 2025年第5期20卷 1495-1504页

作者： Yunting Xiang Xiangxin xing xuyun Hua Yuwen Zhang Xin xue Jiajia Wu Mouxiong Zheng He Wang Jianguang xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina Department of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence(Fudan University) Ministry of EducationShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected ***,differences among reconstruction strategies at the brain network level have not been *** study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve ***–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper ***-state brain functional magnetic resonance imaging was obtained 7 months after *** independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the *** in intra-network resting-state functional connectivity were compared among the *** muscle reinnervation was assessed by behavioral observation(elbow flexion)and *** results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural *** repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor *** thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve *** areas related to cognition and emotion were enhanced after end-to-side nerve *** study revealed important brain networks related to different nerve *** networks may be potential targets for enhancing motor recovery.

关键词： brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity

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Small extracellular vesicles derived from human induced pluripotent stem cell-differentiated neural progenitor cells mitigate retinal ganglion cell degeneration in a mouse model of optic nerve injury

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Neural Regeneration Research 2025年第2期20卷 587-597页

作者： Tong Li Hui-Min xing Hai-Dong Qian Qiao Gao Sheng-Lan xu Hua Ma Zai-Long Chi State Key Laboratory of Ophthalmology Optometry and Visual ScienceEye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina National Clinical Research Center for Ocular Diseases Eye HospitalWenzhou Medical UniversityWenzhouZhejiang ProvinceChina

Several studies have found that transplantation of neural progenitor cells(NPCs)promotes the survival of injured ***,a poor integration rate and high risk of tumorigenicity after cell transplantation limits their clinical *** extracellular vesicles(sEVs)contain bioactive molecules for neuronal protection and *** studies have shown that stem/progenitor cell-derived sEVs can promote neuronal survival and recovery of neurological function in neurodegenerative eye diseases and other eye *** this study,we intravitreally transplanted sEVs derived from human induced pluripotent stem cells(hiPSCs)and hiPSCs-differentiated NPCs(hiPSC-NPC)in a mouse model of optic nerve *** results show that these intravitreally injected sEVs were ingested by retinal cells,especially those localized in the ganglion cell *** with hiPSC-NPC-derived sEVs mitigated optic nerve crush-induced retinal ganglion cell degeneration,and regulated the retinal microenvironment by inhibiting excessive activation of *** analysis further revealed that hiPSC-NPC derived sEVs transported neuroprotective and anti-inflammatory miRNA cargos to target cells,which had protective effects on RGCs after optic nerve *** findings suggest that sEVs derived from hiPSC-NPC are a promising cell-free therapeutic strategy for optic neuropathy.

关键词： exosome miRNA neural progenitor cell neurodegeneration neuroinflammation neuroprotection optic nerve crush optic neuropathy retinal ganglion cell small extracellular vesicles

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Insights into spinal muscular atrophy from molecular biomarkers

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Neural Regeneration Research 2025年第7期20卷 1849-1863页

作者： Xiaodong xing Xinzhu Liu Xiandeng Li Mi Li Xian Wu Xiaohui Huang Ajing xu Yan Liu Jian Zhang Department of Clinical Pharmacy Xinhua HospitalShanghai Jiao Tong University School of MedicineShanghaiChina College of Pharmacy Chongqing Medical UniversityChongqingChina

Spinal muscular atrophy is a devastating motor neuron disease characterized by severe cases of fatal muscle *** is one of the most common genetic causes of mortality among infants aged less than 2 *** research is currently receiving more attention,and new candidate biomarkers are constantly being *** review initially discusses the evaluation methods commonly used in clinical practice while briefly outlining their respective pros and *** also describe recent advancements in research and the clinical significance of molecular biomarkers for spinal muscular atrophy,which are classified as either specific or non-specific *** review provides new insights into the pathogenesis of spinal muscular atrophy,the mechanism of biomarkers in response to drug-modified therapies,the selection of biomarker candidates,and would promote the development of future ***,the successful utilization of biomarkers may facilitate the implementation of gene-targeting treatments for patients with spinal muscular atrophy.

关键词： biomarkers disease progression gene-targeting therapy neurofilaments Nusinersen spinal muscular atrophy(SMA) survival motor neuron therapeutic evaluation treatment outcomes

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Structure and Magnetism of Tetranuclear Metal Complexes

Structure and Magnetism of Tetranuclear Metal Complexes

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中国化学会第六届全国结构化学学术会议

作者： xing xu,yi-Cao Lei,Yu-Xia Huang,Yu-Heng Deng~* Department of Chemistry,Capital Normal University,Beijing,100048

The Cu(II),Mn(II) and Zn(II) complexes with Syn-methoxyimino-a-furanyl-acetic acid(SMIA) have been synthesized and characterized by IR spectra and elementary *** crystal structure of [Cu(SMIA)(phen)](ClO) was determined by X-ray crystallography,which consists of two binuclear copper units connecting each other through two tridentate bridging carboxylates as shown in Fig.1 ***

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