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The significance of the potential link between thrombocytopenia and NETs in COVID-19 should not be ignored

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Infectious Diseases Research 2021年第1期2卷 33-36页

作者： Xian-Kun Wang xing-xiang ren Liu-Luan Zhu Zhi-Hai Chen Center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijingChina Beijing Key Laboratory of Emerging Infectious Diseases Institute of Infectious DiseasesBeijing Ditan HospitalCapital Medical UniversityBeijing 100015China

To the editors,Coronavirus disease 2019(COVID-19)becomes a global pandemic at the end of 2019 and is caused by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).This letter mainly discusses the relationship between neutrophil extracellular traps(NETs)and thrombocytopenia in COVID-19 patients with venous thromboembolism(VTE)or acute respiratory distress syndrome(ARDS).

关键词： acute NETs respiratory

Laboratory indicators of death in severe fever with thrombocytopenia syndrome:a metaanalysis and systematic review

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Infectious Diseases Research 2021年第3期2卷 18-34页

作者： xing-xiang ren Xian-Kun Wang Zi-Ruo Ge Shu-Ping Cui Zhi-Hai Chen Center of Infectious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing100015China

Background:Severe fever with thrombocytopenia syndrome(SFTS)is a tick-borne disease characterized by a fever-induced by severe fever with thrombocytopenia syndrome virus(SFTSV)***:We systematically searched the literature on Web of Science,PubMed,Cochrane Library,Embase,Chinese National Knowledge Infrastructure databases,Sinomed Database,Wan Fang Data,and VIP Database,which describing the death characteristics SFTS(published between January 1,2009 and May 5,2021)and used STATA version 15.0 software to combine data from the selected ***:In the 14150 identified studies,23 were eligible and were included in our *** death characteristics of SFTS are associated with old age,high viral load,high neutrophil ratio,low lymphocyte ratio,low platelet count,elevated liver enzymes,high serum potassium,and high blood urea ***:The results of this meta-analysis can improve our knowledge of the death features of SFTS and necessitate increased attention to the above laboratory indicators to improve the understanding and therapeutic strategies of SFTS.

关键词： Severe fever with thrombocytopenia syndrome Death features Meta-analysis

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空间相机碳纤维框架的设计与优化

光学精密工程 2017年第3期25卷 697-705页

作者：杨帅沙巍陈长征张星祥任建岳中国科学院长春光学精密机械与物理研究所吉林长春130033 中国科学院大学北京100039

设计了一个应用于轻小型空间相机的碳纤维框架。根据光学系统中各光学元件的空间分布特点,通过比较选择结构性能和工艺性能优异的M40J碳纤维复合材料完成了相机框架的结构设计,并使用TC4预埋镶嵌的方法解决了碳纤维框架接口精度低的问... 详细信息

设计了一个应用于轻小型空间相机的碳纤维框架。根据光学系统中各光学元件的空间分布特点,通过比较选择结构性能和工艺性能优异的M40J碳纤维复合材料完成了相机框架的结构设计,并使用TC4预埋镶嵌的方法解决了碳纤维框架接口精度低的问题。对碳纤维框架进行区域划分,采用集成仿真与优化设计方法、遗传算法全局寻优与单纯型下山法局部寻优的组合优化策略对碳纤维框架各区域结构参数进行优化设计。经过优化,碳纤维框架包含TC4预埋件的总质量为15.6kg,仅占相机整机质量的18.4%,相机的一阶频率达104.8Hz。最后通过力学环境试验得到相机整机一阶频率为102Hz,与仿真结果相符,进一步验证了设计的合理性和正确性。文中提出的碳纤维框架方案对轻小型空间相机设计有一定的借鉴意义。文中所采用的优化方法可广泛应用于空间相机光机结构设计中,能大幅度提高设计效率,缩短研制周期。

关键词：空间相机框架碳纤维复合材料集成优化组合优化策略

Studied microRNA gene expression in human hepatocellular carcinoma by micro RNA microarray techniques

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World Journal of Gastroenterology 2015年第44期21卷 12605-12611页

作者： Jian-xiang Niu xing-Kai Meng Jian-Jun ren Department of General Surgery of the Affiliated Hospital of Inner Mongolia Medical University

AIM: To achieve a better understanding of the molecular mechanisms of micro RNA expression changes involved in hepatocellular ***: In this research process, patients were not treated with antivirals, immunosuppressants or immunomodulators for at least 6 mo before collecting serum. The study population was composed of 35 outpatient hepatitis B virus(HBV) cases and 12 healthy control cases from the Affiliated Hospital of Inner Mongolia Medical University(Inner Mongolia, China) from July 2013 to April 2014. The 35 HBV cases were divided into two groups: a hepatocirrhosis group with 20 cases and a liver cancer group with 15 cases. All 35 cases carried HBs Ag. The diagnostic criteria followed the European Association for the Study of the Liver 2012(EASL2012) standards. Micro RNA(mi RNA) was extracted from a control group of patients, a group with hepatocirrhosis and a group with liver cancer and its quality was analyzed using the human V2 micro RNA expression beadchip. Cluster analysis and a radar chart were then applied to the mi RNA ***: The mi RNA-qualified rate of human serum samples was 93%. The concentration of a single sample was > 200 ng/μL and the volume was > 5 μ*** mi RNA serum samples were uncontaminated by the genome. The Mann-Whitney test showed significant differences in mi RNA between each group, with a detection P-value of < 0.05. Illumina software was set up with Diff Score set to ± 13, meaning that P = *** were significant changes in mi RNA expression between the three groups. mi RNA-183 was the most up-regulated, followed by mi RNA-373. mi RNA-129 and mi RNA-188 were both strongly down-regulated and mi RNA-378 was down-regulated a small amount. The liver cancer group had greater changes, which indicated that changes in mi RNA expression levels were caused by hepatocirrhosis. The liver cancer disease course then further increased these changes. In the pentagon created by these five mi RNAs, three groups showed signif

关键词： Hepatocellular carcinoma Micro RNA Expression Micr

Coordinate Transformation and Exact Solutions of Schrodinger Equation with Position-Dependent Effective Mass

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Communications in Theoretical Physics 2007年第6期47卷 1001-1009页

作者： JU Guo-xing CAI Chang-Ying xiang Yang ren Zhong-Zhou Department of Physics Nanjing University Nanjing 210093 China Department of Physics Jinggangshan University Ji＇an 343009 China Center of Theoretical Nuclear Physics National Laboratory of Heavy-Ion Accelerator Lanzhou 730000 China

Using the coordinate transformation method, we solve the one-dimensional Schrodinger equation with position-dependent mass. The explicit expressions for the potentials, energy eigenvalues, and eigenfunctions of the systems are given. The eigenfunctions can be expressed in terms of the Jacobi, Hermite, and generalized Laguerre polynomials. All potentials for these solvable systems have an extra term Vm, which is produced from the dependence of mass on the position, compared with those for the systems of constant mass. The properties of Vm for several mass functions are discussed.

关键词： coordinate transformation Schrodinger equation position-dependent mass eigenfunction special functions

Experimental Investigation of Multi-Mode Vortex-Induced Vibration of Flexible Risers with Different Mass Ratios

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China Ocean Engineering 2023年第1期37卷 1-15页

作者： WANG Yu LOU Min ren Xiao-hui LIANG Wei-xing LI xiang DANG Peng-bo School of Petroleum Engineering China University of Petroleum(East China)Qingdao 266580China Key Laboratory of Unconventional Oil&Gas Development(China University of Petroleum(East China)) Ministry of EducationQingdao 266580China College of Civil Engineering and Architecture Shandong University of Science and TechnologyQingdao 266590China

Experiments were conducted on risers with different mass ratios to study the effect of mode conversion and spanwise correlation. The slenderness ratio of the riser model was set as 169, and the Reynolds numbers are 1600-14400. The dynamic responses of riser models versus reduced velocity were analyzed, and the spanwise displacement, frequency,and trajectory of the mode conversion from the lower to the higher mode were explored. The results revealed that the riser model with a higher mass ratio excites a higher number of modes. The conversion region of multi-mode competition exists and narrows with the increasing mass ratio. Mode conversion is continuous and manifests as the transmission of peaks and troughs in mode shape: the peaks and troughs of mode shape move up in the mode stable development region and move down in the mode conversion region. The single-mode dominating vibration exhibits a standing wave feature, and the traveling wave feature is significant in the mode conversion region. Furthermore, the frequency jump is always transmitted from the trough to the peak of the mode shape, and finally, all the axial positions vibrate at the same frequency. The trajectory in the mode conversion region deviates from the 8-shape and recovers the standard8-shape at the middle and late stages of the mode stable development region.

关键词： vortex-induced vibration dynamic response mode conversion mass ratio mode weight

Reduction of Pyrite Cinder Pellets Mixed with Coal Powder

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Journal of Iron and Steel Research International 2014年第7期21卷 653-659页

作者： xiang-dong xing Jian-liang ZHANG Zhen-yang WANG Ke-xin JIAO xing-le LIU Shan ren College of Metallurgical and Ecological Engineering University of Science and Technology Beijing College of Metallurgical Engineering Xi'an University of Architecture and Technology

Direct reduction of pyrite cinder in a rotary hearth furnace （RHF） was studied under the condition of labo ratory simulation. Effects of reduction temperature, reduction time, molar ratio of carbon to oxygen, .and CaO addition on metallization rate as well as compressive strength of the pellets after reduction were discussed. The results showed that the metallization rate and compressive strength were 93.9% and 2 160 N per pellet respectively under the conditions of the reduction temperature of 1 200 ℃, the reduction time of 16 min, and the molar ratio of carbon to oxygen （xc/xo） of 1. 0; adding 2.5% CaO was beneficial to sulfur enrichment in slag phase of pellet, and metal- lization rate increased slightly while compressive strength decreased.

关键词： pyrite cinder metallization rate compressive strength pellet coal powder

Controlling the Balance of Photoluminescence and Photothermal Effect in Cyanostilbene-Based Luminescent Liquid Crystals

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Chinese Journal of Chemistry 2022年第8期40卷 902-910页

作者： xiang-Jian Cao Wei Li Jiahua Li Lin Zou xing-Wang Liu xiang-Kui ren Zhen-Qiang Yu School of Chemical Engineering and Technology State Key Laboratory of Chemical EngineeringTianjin UniversityTianjin 300350China College of Chemistry and Environmental Engineering Institute of Low-dimensional Materials Genome InitiativeShenzhen UniversityShenzhenGuangdong 518071China

Molecular motions of the luminescent liquid crystals(LLCs)show a significant effect on fluorescent emission and heat *** this article,a series of cyanostilbene-based LLCs(CSs:CS1-6,CS1-12,CS2-6 and CS2-12)are synthesized to investigate how the pho-toluminescence and photothermal effect *** these materials,the mesogens peripheried by single alkyl chains formed enantiotropic nematic(CS1-6)or smectic C(CS1-12)phase with different alkyl tail *** the single aliphatic chain is re-placed by mini-dendrons,room temperature(RT)monotropic hexagonal columnar phase(CS2-12)or molecular liquid(CS2-6)is *** results revealed that all these materials exhibited high efficiency emission with the highest quantum yield reaching 59.0%.The photoluminescence and photothermal effect can be effectively tuned by dispersing CSs into a commercially available RT liquid crystal matrix 8CB,which output significantly improved photothermal conversion efficiency of 63.2%.Furthermore,the pho-tothermal can rapidly trigger the Smectic A-Nematic-Isotropic sequence transitions of 8CB doped with *** work paves a way of adjusting the balance of photoluminescence and photothermal properties of the LLC materials.

关键词： Aggregation-induced emission Liquid crystals Molecular motions Photothermal effect Phase transitions

Cradle for the newborn Monochamus saltuarius:Microbial associates to ward off entomopathogens and disarm plant defense

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Insect Science 2023年第4期30卷 1165-1182页

作者： Si-Xun Ge Jia-xing Li Zhuo-Heng Jiang Shi-xiang Zong Li-Li ren Bejing Key Laboratory for Forest Pest Control Bejing Forestry UniversityBeijingChina School of Science Westlake UniversityHangzhouChina Sino-French Joint Laboratory for Invasive Forest Pests in Eurasia Bejing Forestry University-French National Research Institute for AgricultureFood and Environment(INRAE)BejingChina

The Japanese pine sawyer,Monochamus saltuarius,as a beetle vector of Bur-saphelenchus xylophilus(pine wood nematode),is an economically important forest pest in *** feed on the phloem and xylem of conifers,*** needs to overcome various stress factors,including coping with entomopathogenic bacteria and also various plant secondary compounds(PSCs).As an important adaptation strategy to colonize host trees,*** deposit eggs in oviposition pits to shield their *** pits har-bor bacterial communities that are involved in the host adaptation of *** to the ***,the composition,origin,and functions of these oviposition pit bacteria are rarely *** this study,we investigated the bacterial community associated with *** oviposition pits and their ability to degrade *** showed that the bacterial community structure of *** oviposition pits significantly differed from that of uninfected ***,the oviposition pit bacteria were predicted to be enriched in PSC degradation *** microbial community also harbored a lethal strain of Serratia,which was significantly ***,metatranscriptome anal-ysis indicated that genes involved in PSCs degradation were expressed complementarily among the microbial communities of oviposition pits and *** vitro degrada-tion showed that bacteria cultured from oviposition pits degraded more monoterpenes and flavonoids than bacteria cultured from uninfected phloem *** of ovipo-sition pits increased the mortality of newly hatched larvae and resulted in a significant decrease in body weight in the early ***,our results reveal that *** construct oviposition pits that harbor a diverse microbial community,with stronger PSCs degradation abilities and a low abundance of entomopathogenic bacteria,resulting in the increased fitness of newly hatched larvae.

关键词： community structure entomopathogenic bacteria host plant adaptation plant secondary metabolites symbiotic bacteria