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太阳能学报 1992年第1期13卷 66-70页

作者：王给祥孙玉茹王兴瑞王岚刘波中国科学院长春应用化学研究所长春130022

本文报道了一种具有多层结构的新型蒸发源,指出了它的特点和用该蒸发源制备CdS太阳电池的结果。

关键词：电池太阳能蒸发源多层结构

Binding to The Minor Groove of the Double-strand,Tau Protein Prevents DNA from Damage by Peroxidation

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Binding to The Minor Groove of the Double-strand,Tau Protein...

2008年全国生物化学与分子生物学学术大会

作者： Yan Wei Mei-hua Qu xing-sheng wang lan Chen Dong-liang wang Ying Liu Qian Hua Rong-qiao He (State Key Laboratory of Brain and Cognitive Science,Institute of Biophysics,Chinese Academy of Sciences,Beijing 100101,China)

Tau,an important microtubule associated protein,has been found to bind to DNA,and to be localized in the nuclei of both neurons and some non-neuronal ***,using electrophoretic mobility shitting assay(EMSA) in the presence of DNA with different chain-lengths,we observed that tau protein favored binding to a 13 bp or

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老年高血压并发腔隙性脑梗死的诊疗效果探讨

黑龙江医学 2019年第12期43卷 1460-1461页

作者：戴顺民王兴兰麻城市人民医院急诊科

目的探讨老年高血压并发腔隙性脑梗死疾病的诊断方法与急诊治疗措施。方法选择麻城市人民医院2016年1月—2018年11月期间收治的老年高血压并发腔隙性脑梗死患者,共计120例,所选患者入院后经MRI或CT检查确诊,对其进行降压、改善脑循环、... 详细信息

目的探讨老年高血压并发腔隙性脑梗死疾病的诊断方法与急诊治疗措施。方法选择麻城市人民医院2016年1月—2018年11月期间收治的老年高血压并发腔隙性脑梗死患者,共计120例,所选患者入院后经MRI或CT检查确诊,对其进行降压、改善脑循环、增强脑供血和处理并发症等治疗,分析患者的诊疗方法与效果。结果观察组患者治疗后痊愈60例(50%),显效40例(33.3%),有效20例(16.7%),无1例死亡,有效率为100%。治疗前后患者24hSBP、24hDBP、24hPP、PPI组间对比差异有统计学意义(P<0.05)。结论为老年高血压并发腔隙性脑梗死患者及时提供正确有效的诊断和治疗,能够有效缓解患者临床症状,提高患者的生存率。

关键词：老年高血压腔隙性脑梗死诊断急诊治疗

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人文素质教育的价值定位

江苏教育学院学报（社会科学版） 2002年第3期18卷 10-12页

作者：王兴兰江苏省海安县教师进修学校江苏海安226600

关于素质教育的任何阐述 ,都有可能坠入老生常谈。但不可否认的是 ,对人的灵魂的教育与洗礼 ,应该是教育的一条内在的真正贯穿始终的主线。人文素质教育的提出 ,也正是基于此 ,对于素质教育的重新回眸与审视 ,它试图表明 ,人文素质教育... 详细信息

关于素质教育的任何阐述 ,都有可能坠入老生常谈。但不可否认的是 ,对人的灵魂的教育与洗礼 ,应该是教育的一条内在的真正贯穿始终的主线。人文素质教育的提出 ,也正是基于此 ,对于素质教育的重新回眸与审视 ,它试图表明 ,人文素质教育是主体性教育的必然要求 ,是对教育本质功能的发挥 ,目标是达成对教育的深度突破。

关键词：价值定位素质教育人文教育主体性教育教育本质终身学习

Composite nonlinear feedback control for output regulation problem of linear discrete-time systems with input saturation

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Journal of Systems Engineering and Electronics 2014年第6期25卷 1043-1055页

作者： Chongwen wang xing Chu Weiyao lan School of Software Beijing Institute of Technology Department of Automation Xiamen University

Transient performance for output regulation problems of linear discrete-time systems with input saturation is addressed by using the composite nonlinear feedback（CNF） control technique. The regulator is designed to be an additive combination of a linear regulator part and a nonlinear feedback part. The linear regulator part solves the regulation problem independently which produces a quick output response but large oscillations. The nonlinear feedback part with well-tuned parameters is introduced to improve the transient performance by smoothing the oscillatory convergence. It is shown that the introduction of the nonlinear feedback part does not change the solvability conditions of the linear discrete-time output regulation problem. The effectiveness of transient improvement is illustrated by a numeric example.

关键词： output regulation composite nonlinear feedback in-put saturation transient performance discrete-time system

吲哚-3-丁酸类衍生物的合成及体外降糖活性研究

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化学试剂 2019年第4期41卷 360-364页

作者：张吉泉杜瑶王兴兰文林静马晓汤磊贵州医科大学药学院贵州贵阳550004 贵州医科大学化学合成药物研发利用工程技术研究中心贵州贵阳550004

以4-苄氧基苯肼盐酸盐及6-氧代庚酸乙酯为原料,经Fischer吲哚环合、还原、酰胺化及水解等步骤得到7个目标化合物。目标化合物的结构均经高分辨质谱、核磁共振氢谱及碳谱确证。采用人肝癌Hep G2细胞来评价所合成目标化合物的体外降糖活... 详细信息

以4-苄氧基苯肼盐酸盐及6-氧代庚酸乙酯为原料,经Fischer吲哚环合、还原、酰胺化及水解等步骤得到7个目标化合物。目标化合物的结构均经高分辨质谱、核磁共振氢谱及碳谱确证。采用人肝癌Hep G2细胞来评价所合成目标化合物的体外降糖活性。结果表明,目标化合物均具有一定的降糖活性。其中,4-(5-苄氧基-1-(4-甲磺酰基苯甲酰基)-2-甲基-2,3-二氢-吲哚-3-基)丁酸的降糖活性强于阳性对照二甲双胍,但略微弱于先导化合物GY3。为后续衍生物的设计与合成提供了新思路。

关键词：吲哚降糖活性腺苷酸活化蛋白激酶合成

Tuning the interfacial reaction environment via pH-dependent and induced ions to understand C–N bonds coupling performance in NO3- integrated CO2 reduction to carbon and nitrogen compounds over dual Cu-based N-doped carbon catalyst

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Journal of Energy Chemistry 2025年第1期100卷 273-285页

作者： Tianhang Zhou Chen Shen Zhenghao Wu xingying lan Yi Xiao College of Carbon Neutrality Future Technology State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) Institute of Materials Science TU Darmstadt Department of Chemistry Xi'an Jiaotong-Liverpool University Department of Mechanical and Mechatronics Engineering and Waterloo Institute of Nanotechnology University of Waterloo Waterloo

Dual atomic catalysts （DAC）,particularly copper （Cu2）-based nitrogen （N） doped graphene,show great potential to effectively convert CO2and nitrate （NO3-） into important industrial chemicals such as ethylene,glycol,acetamide,and urea through an efficient catalytical process that involves C–C and C–N ***,the origin of the coupling activity remained unclear,which substantially hinders the rational design of Cu-based catalysts for the N-integrated CO2reduction reaction （CO2RR）.To address this challenge,this work performed advanced density functional theory calculations incorporating explicit solvation based on a Cu2-based N-doped carbon (Cu2N6C10) catalyst for *** calculations are aimed to gain insight into the reaction mechanisms for the synthesis of ethylene,acetamide,and urea via coupling in the interfacial reaction *** to the sluggishness of CO2,the formation of a solvation electric layer by anions （F-,Cl-,Br-,and I-） and cations (Na+,Mg2+,K+,and Ca2+) leads to electron transfer towards the Cu *** process significantly accelerates the reduction of *** results reveal that*CO intermediates play a pivotal role in N-integrated ***,the Cu2-based N-doped carbon catalyst examined in this study has demonstrated the most potential for C–N coupling to *** findings reveal that through the process of a condensation reaction between*CO and NH2OH for urea synthesis,*NO3-is reduced to*NH3,and*CO2to*CCO at dual Cu atom *** dual-site reduction facilitates the synthesis of acetamide through a nucleophilic reaction between NH3and the ketene ***,we found that the I-and Mg2+ions,influenced by pH,were highly effective for acetamide and ammonia synthesis,except when F-and Ca2+were ***,the mechanisms of C–N bond formation were investigated via ab-initio molecular dynamics simulations,and we found that adjusting the micro-environment can change the dominant side reaction,shift

关键词： pH-dependent micro-environments C–N coupling Dual Cu-based nitrogen carbon catalysts Explicit solvation model Ion stabilizer AIMD

Link Prediction Method Fusion with Local Structural Entropy for Directed Network

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Chinese Journal of Electronics 2024年第1期33卷 204-216页

作者： Shuxin LIU Hongchang CHEN lan WU Kai wang xing LI People’s Liberation Army Strategic Support Force Information Engineering University

Link prediction utilizes accessible network information to complement or predict the network *** is an important prerequisite for link prediction which means links more likely occurs between two similar nodes. Existing methods utilize the similarity of nodes but neglect of network structure. However the link direction leads to a far more complex structure and contains more information useful than the undirected networks. Most classic methods are difficult to depict the distribution of the network structure with incidental direction so the similarity characteristics of the network structure itself are lost. In this respect, a new method of local structure entropy is proposed to depict the directed structural distribution characteristics, which can be used to evaluate the degree of local structural similarity of nodes and then applied to link prediction methods. Experimental results on 8 real directed networks show that this method is effective for both area under the receiver operating characteristic curve(AUC)and ranking-score measures, and improved predictive capacity of the baseline methodology.

关键词： Correlation Current measurement Area measurement Prediction methods Receivers Benchmark testing Entropy

Unraveling the therapeutic potential of Calculus Bovis in liver cancer:A novel step for targeted cancer treatment

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World Journal of Gastroenterology 2025年第3期31卷 127-129页

作者： xing-Yu Chen Xiang lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

Hepatocellular carcinoma is one of the leading causes of cancer-related deaths globally,and effective treatments are urgently *** present study aimed to investigate the inhibitory effect of Calculus Bovis(CB)on liver cancer and the underlying *** inhibited M2 tumor-associated macrophage polarization and modulated the Wnt/β-catenin signaling pathway,thereby suppressing the proliferation of liver cancer *** inhibitory effect on liver cancer growth was confirmed by both in vivo and in vitro experiments(detailed by Huang et al).The present study provides a theoretical basis for the application of CB for the treatment of liver cancer,providing new avenues for liver cancer treatment.

关键词： Calculus Bovis Liver cancer M2 tumor-associated macrophage polarization Wnt/β-catenin Pathway Tumor microenvironment

Factors Influencing Formation of Sclerotia in Grifola umbellate （Pers.） Pilaet Under Artificial Conditions

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Journal of Integrative Plant Biology 2006年第11期48卷 1312-1317页

作者： Xian-Hao Cheng Shun-xing Guo Chun-lan wang Laboratory of Medicinal Fungi Institute of Medicinal Plants Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100094 China

The effects of substrate composition and temperature on myceilal growth and sclerotium production in Grlfola umbellate （Pers.） Pilaet were Investigated In the present study. The Induction of sclerotla of G. umbellate was affected greatly by the type of medium, as well as the type of carbon source. Malt-extract agar was able to induce the production of sclerotia. The production of sclerotia was also observed when the carbon source in the GPC agar medium （glucose 20 g/L, peptone 6 g/L, corn steep liquor 10 g/L, and agar 15 g/L） was replaced with glycerol or mannitol. Altering the composition of the GPC medium with milk powder, thiamine hydrochlorlde, extract of Armlllarla mellea, active clay, dlatomite, kaolin, or arginlne did not induce the production of sclerotla. A temperature range of 18-25 ℃ was suitable for both mycellai growth and sclerotium formation. Glycerol significantly Induced slerotium formation on nutrient supplemented with sawdust substrates In bottle culture. 24S-Polyporusterone A and polyporusterone B were assayed In samples of natural and cultured sclerotla. Both natural and cultured sclerotla contained 24S- polyporusterone A and polyporusterone B.

关键词： carbon sources glycerol Grifola umbellate mannitol polyporusterone, sclerotia.