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Optical coherence tomography guided treatment avoids stenting in an antiphospholipid syndrome patient:A case report

World Journal of Clinical Cases 2020年第11期8卷 2399-2405页

作者： Bei-Bei Du xing-tong wang Ya-Liang tong Kun Liu Pei-Pei Li Xiang-Dong Li Ping Yang Ying wang Department of Cardiology The Third Hospital of Jilin UniversityJilin Provincial Cardiovascular Research InstituteJilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular DiseaseChangchun 130031Jilin ProvinceChina Department of Hematology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina

BACKGROUND Increasing attention has been paid to acute myocardial infarction(AMI)in young female patients for whom secondary factors should be considered during the diagnostic ***-phospholipid syndrome(APS),a rare autoimmune disease that is most common in young female patients,is reportedly related to *** date,coronary interventions,particularly stenting,remains controversial in this special clinical *** SUMMARY A 26-year-old female patient was admitted to hospital for acute chest pain,palpitations,and *** had a past medical history of APS and pulmonary *** angiography showed acute occlusion of the proximal left anterior descending *** repeated thrombus aspirations,residual thrombus and mild stenosis were found in the proximal left anterior descending *** coherence tomography(OCT)was done,which confirmed the non-atherosclerosis coronary thrombosis and an intact intima in this *** or avoiding stenting based on follow-up intracoronary findings with intensified antithrombotic treatment was *** week later,coronary angiography and OCT confirmed an intact intima with no injury and no residual *** 3-mo telephone follow-up reported a good *** APS can cause acute non-atherosclerosis coronary thrombosis which presents as an AMI in young female *** OCT findings can guide interventional strategies in this special clinical scenario.

关键词： Anti-phospholipid syndrome Myocardial infarction Optical coherence tomography Coronary intervention Coronary thrombosis Case report

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Rescue treatment and follow-up intervention of a left main acute myocardial infarction with typical carina shift under 3D optical coherence tomography: A case report

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World Journal of Clinical Cases 2020年第4期8卷 848-853页

作者： Bei-Bei Du Ya-Liang tong xing-tong wang Guo-Hui Liu Kun Liu Ping Yang Yu-Quan He Department of Cardiology China-Japan Union Hospital of Jilin UniversityJilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular DiseaseChangchun 130031Jilin ProvinceChina Department of Hematology and Oncology Cancer CenterThe First Hospital of Jilin UniversityChangchun 130031Jilin ProvinceChina

BACKGROUND Coronary intervention for bifurcation lesions is still challenging for interventional *** main(LM)bifurcation lesions have a higher risk due to the vast blood supply in this area and treatment choice is *** compromise of the side branch decreases patient prognosis,and its management is still an issue despite the different strategies and devices *** SUMMARY A 42-year-old male patient was admitted to hospital due to chest pain and *** angiography showed acute LM *** thrombus aspiration,a LM bifurcation lesion *** angiography was repeated one week later,and at the same time,3D optical coherence tomography(OCT)was carried out to better show the geometry of the bifurcation,which confirmed that the stenosis in the ostial left circumflex artery was caused by a long *** assessment of the plaque characteristics and the minimum lumen area,the cross-over strategy,kissing balloon inflation and proximal optimization technique were chosen to treat the bifurcation lesion.A“moving”carina was found twice during the *** stent apposition and expansion were confirmed by OCT after proximal optimization *** three-month follow-up showed good recovery and normal cardiac *** 3D-OCT can facilitate decision-making for coronary interventions in patients with critical bifurcation lesions.

关键词： 3-Dimensional optical coherence tomography Left main bifurcation Acute myocardial infarction Carina shift Kissing balloon inflation Case report

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Effect of chidamide on treating hepatosplenic T-cell lymphoma: A case report

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World Journal of Clinical Cases 2020年第14期8卷 3122-3129页

作者： xing-tong wang Wei Guo Mo Sun Wei Han Zhong-Hua Du Xiu-Xiu wang Bei-Bei Du Ou Bai Department of Hematology The First Hospital of Jilin UniversityJilin Provincial Hematology Research InstituteNational Key DisciplineChangchun 130021Jilin ProvinceChina Department of Pathology The First Hospital of Jilin UniversityChangchun 130021Jilin ProvinceChina Department of Cardiology The Third Hospital of Jilin UniversityChangchunJilin Province 130031China

BACKGROUND Hepatosplenic T-cell lymphoma(HSTCL)is a rare subtype of non-Hodgkin’s lymphoma,which has an aggressive clinical course and an extremely poor *** is a novel,orally active,benzamide-type histone deacetylase(HDAC)inhibitor that has been used for peripheral T-cell lymphoma(PTCL)***,to date,there has been no report of the treatment and effect of the HDAC inhibitor chidamide in HSTCL,which is a special subtype of *** SUMMARY A 45-year-old male patient was admitted with splenomegaly and slight *** was diagnosed with HSTCL via *** patient was treated with fractionated cyclophosphamide,vincristine,doxorubicin,and dexamethasone alternating with high-dose methotrexate and cytarabine regiment as inductive ***,the disease progressed rapidly during chemotherapy before a suitable allogeneic gene transplant donor was *** chidamide-combined chemotherapy regimen and single-drug oral maintenance regimen achieved complete remission,duration of response of 9 mo,and overall survival of 15 *** The novel agent chidamide can be used in HSTCL to achieve deep remission and improve the duration of response and overall survival.

关键词： Hepatosplenic T-cell lymphoma Gamma-delta T-cell lymphoma Chidamide Novel agent Case report

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Construction of NIM sub-network regulated by Liuwei Dihuang decoction and its characteristics

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中国药理学与毒理学杂志 2018年第4期32卷 306-307页

作者： tong-xing wang Lu HAN Xiao-rui CHENG Wen-xia ZHOU Yong-xiang ZHANG Beijing Institute of Pharmacology and Toxicology Beijing 100850 China The State Key Laboratory of Toxicology and Medical Countermeasures Beijing 100850 China

OBJECTIVE To construct the neuroendocrine immunomodulation(NIM) sub-network regulated by Liuwei Dihuang decoction(LW) and analyze its *** We took the GSE57273 in GEO database and screened the differentially expressed genes(DEGs)(P10).Among them,there were 19 NIM signaling molecules in which only ESR1 changed significantly and 3 non-DEGs(NFATC2,RARA,TP53).However,the *** of the hub nodes were significantly *** The results suggested that LW might mainly regulate the non-hub nodes to recovery of the network imbalance of the body in the state of disease.

关键词：六味地黄汤神经内分泌治疗方法临床分析

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Treatment of severe upper gastrointestinal bleeding caused by Mallory-Weiss syndrome after primary coronary intervention for acute inferior wall myocardial infarction: A case report

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World Journal of Clinical Cases 2019年第24期7卷 4407-4413页

作者： Bei-Bei Du xing-tong wang Xiang-Dong Li Pei-Pei Li Wei-Wei Chen Si-Ming Li Ping Yang Department of Cardiology China-Japan Union Hospital of Jilin UniversityJilin Provincial Engineering Laboratory for Endothelial Function and Genetic Diagnosis of Cardiovascular DiseaseChangchun 130031Jilin ProvinceChina Department of Hematology and Oncology Cancer CenterThe First Hospital of Jilin UniversityChangchun 130031Jilin ProvinceChina

BACKGROUND Upper gastrointestinal bleeding(UGIB) after an acute myocardial infarction(AMI) is not an uncommon complication. Acute UGIB caused by Mallory-Weiss syndrome(MWS) is usually a dire situation with massive bleeding and hemodynamic instability. Acute UGIB caused by MWS after an AMI has not been previously *** SUMMARY A 57-year-old man with acute inferior wall ST elevation myocardial infarction underwent a primary coronary intervention of the acutely occluded right coronary artery. Six hours after the intervention, the patient had a severe UGIB,followed by vomiting. His hemoglobin level dropped from 15.3 g/d L to 9.7 g/d L. In addition to blood transfusion and a gastric acid inhibition treatment,early endoscopy was employed and MWS was diagnosed. Bleeding was stopped by endoscopic placement of titanium *** Bleeding complications after stent implantation can pose a dilemma. MWS is a rare but severe cause of acute UGIB after an AMI that requires an early endoscopic diagnosis and a hemoclip intervention to stop bleeding.

关键词： Acute upper gastrointestinal bleeding Mallory-Weiss syndrome Primary coronary intervention Acute myocardial infarction Endoscopic treatment Case report

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Selenium deficiency exacerbates ROS/ER stress mediated pyroptosis and ferroptosis induced by bisphenol A in chickens thymus

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Journal of Environmental Sciences 2025年第2期148卷 13-26页

作者： Kun wang Xu Shi Hongjin Lin tong Xu Shiwen Xu College of Veterinary Medicine Northeast Agricultural UniversityHarbin 150030China Key Laboratory of the Provincial Education Department of Heilongjiang for Common Animal Disease Prevention and Treatment Harbin 150030China

Bisphenol A(BPA)is an industrial pollutant that can cause immune *** acts as an antioxidant,as selenium deficiency often accompanies oxidative stress,resulting in organ *** study is the first to demonstrate that BPA and/or selenium deficiency induce pyroptosis and ferroptosis-mediated thymic injury in chicken and chicken lymphoma cell(MDCC-MSB-1)via oxidative stress-induced endoplasmic reticulum(ER)*** established a broiler chicken model of BPA and/or selenium deficiency exposure and collected thymus samples as research subjects after 42 *** results demonstrated that BPA or selenium deficiency led to a decrease in antioxidant enzyme activities(T-AOC,CAT,and GSH-Px),accumulation of peroxides(H2O2 and MDA),significant upregulation of ER stress-relatedmarkers(GRP78,IER 1,PERK,EIF-2α,ATF4,and CHOP),a significant increase in iron ion levels,significant upregulation of pyroptosis-related gene(NLRP3,ASC,Caspase1,GSDMD,IL-18 and IL-1β),significantly increase ferroptosis-related genes(TFRC,COX2)and downregulate GPX4,HO-1,FTH,*** vitro experiments conducted in MDCC-MSB-1 cells confirmed the results,demonstrating that the addition of antioxidant(NAC),ER stress inhibitor(TUDCA)and pyroptosis inhibitor(Vx765)alleviated oxidative stress,endoplasmic reticulum stress,pyroptosis,and ***,this study concludes that the combined effects of oxidative stress and ER stress mediate pyroptosis and ferroptosis in chicken thymus induced by BPA exposure and selenium deficiency.

关键词： Bisphenol A Selenium deficiency ROS/ER stress Pyroptosis Ferroptosis Thymic injury

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Optimizing cooling approach of spiral coil for an electromagnetic steel teeming system of ladle in continuous casting production

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Journal of Iron and Steel Research International 2025年第1期32卷 85-94页

作者： Ming He Qing-wei wang Li-jia Zhao wang-zhong Mu xing-an Liu Qiang wang College of Horticulture Shenyang Agricultural UniversityShenyang110866LiaoningChina Key Laboratory of Electromagnetic Processing of Materials(Ministry of Education) Northeastern UniversityShenyang110819LiaoningChina Key Laboratory of Protected Horticulture(Ministry of Education) Shenyang Agricultural UniversityShenyang110866LiaoningChina Department of Materials Science and Engineering KTH Royal Institute of TechnologyStockholm10044Sweden

To address the current issues with the conventional slide gate system utilized in the steel teeming process,a unique electromagnetic induction controlled automated steel teeming(EICAST)technology has been *** means of spiral coil in this technology is directly related to its service ***,heat transfer processes of air cooling and spray cooling were compared and ***,the impacts of water temperature,water flow rate and air flow rate were examined in order to maximize the spray cooling *** maintain coil temperature at a low value consistently throughout the entire thermal cycle process of the ladle,a combined cooling mode was finally *** simulation was applied to examine the coil temperature variation with different cooling systems and *** coil operation,spray cooling is said to be more *** controlling the water flow rate and air flow rate,the spray cooling effect is ***,water temperature has little or no impact when using spray *** cooling during the secondary refining process and spray cooling prior to coil operation are combined to further lower coil *** the direction of the spray cooling is from bottom to top,the coil temperature is lowered below 165℃.A practical induction coil cooling plan was provided for the EICAST technology’s production process.

关键词： Electromagnetic induction controlled automated steel teeming technology Spiral coil Spray cooling Heat transfer Continuous casting

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Recent advances of cerium compounds in functional coatings:Principle,strategies and applications

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Journal of Rare Earths 2025年第2期43卷 227-245页

作者： Kai An Youqiang wang Yi Sui Yongquan Qing Wei tong Xuezhao wang Changsheng Liu School of Mechanical and Automotive Engineering Qingdao University of Technology State Key Laboratory of Baiyunobo Rare Earth Resource Researches and Comprehensive Utilization Baotou Research Institute of Rare Earths School of Materials Science and Engineering Northeastern University Center for Nano and Micro Mechanics Tsinghua University

Cerium(Ce) compounds have attracted considerable attention as key components in functional coatings due to their many outstanding *** work provides a comprehensive review of recent advances in the application of Ce in functional *** role of Ce in the improvement of functional properties such as corrosion-resistance,self-healing,superhydrophobicity,wear-resistance,and UV shielding is reviewed from the perspective of functional mechanism and applied ***,the strategies,processes,practical problems,and current challenges in the research of functional coatings containing Ce are summarized and *** objective is to highlight the great potential of Ce in functional coatings,and to explore new applications of Ce in the development of novel ***,this work aims to enhance the application value of Ce,solving the problem of unbalanced application of rare-earth elements.

关键词： Cerium Functional coatings Corrosion Superhydrophobicity UV resistance Rare earths

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Isospin splitting of the Dirac mass probed using the relativistic Brueckner-Hartree-Fock theory

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Nuclear Science and Techniques 2025年第2期36卷 123-130页

作者： Pianpian Qin Qiang Zhao Hui tong Chencan wang Sibo wang Department of Physics and Chongqing Key Laboratory for Strongly Coupled Physics Chongqing UniversityChongqing 401331China Center for Exotic Nuclear Studies Institute for Basic ScienceDaejeon 34126Korea Helmholtz-Institut für Strahlen-und Kernphysik and Bethe Center for Theoretical Physics Universität BonnBonn D-53115Germany School of Physics and Astronomy Sun Yat-Sen UniversityZhuhai 519082China

The isospin splitting of the Dirac mass obtained using the relativistic Brueckner-Hartree-Fock(RBHF)theory was thor-oughly *** the perspective in the full Dirac space,the long-standing controversy between the momentum-independent approximation(MIA)method and the projection method on the isospin splitting of the Dirac mass in asymmetric nuclear matter was analyzed in *** found that the assumption procedure of the MIA method,which assumes that single-particle potentials are momentum independent,is not a sufficient condition that directly leads to the opposite sign of the isospin splitting of the Dirac mass,whereas the extraction procedure of the MIA method,which extracts single-particle potentials from single-particle potential energy,changes the sign.A formal expression of the Dirac mass was obtained by approximately solving a set of equations involved in the extraction *** opposite isospin splitting of the Dirac mass was mainly caused by the extraction procedure,which forcibly assumed that the momentum dependence of the single-particle potential energy was in a quadratic form,in which the strength was solely determined by a constant scalar *** understanding of the isospin splitting of the Dirac mass from ab initio calculations could enhance our knowledge of neutron-rich systems,such as exotic nuclei and neutron stars.

关键词： Dirac mass Relativistic Brueckner-Hartree-Fock theory Single-particle potential Momentum dependence

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An ionic liquid assisted hydrogel functionalized silica stationary phase for mixed-mode liquid chromatography

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Chinese Chemical Letters 2025年第1期36卷 491-495页

作者： tong Zhang Xiaojing Liang Licheng wang Shuai wang Xiaoxiao Liu Yong Guo Lanzhou Institute of Chemical Physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China Lanzhou Institute for Food and Drug Control Key Laboratory of Pesticide and Veterinary Drug Monitoring for State Market RegulationLanzhou 730050China

An ionic liquid assisted hydrogel modified silica was synthesized using a one-pot polymerization and physical coating technique and subsequently applied to mixed-mode liquid *** techniques,including Fourier transform infrared spectroscopy(FT-IR),X-ray photoelectron spectroscopy(XPS),and elemental analysis,etc.,confirmed the successful prepared of this innovative stationary *** unique combination of amide,long alkyl chain,and imidazole ring in the hydrogel coating enables the stationary phase to function effectively in hydrophilic/reversed-phase/ion exchange liquid ***,the stationary phase exhibited superior separation performance owing to the synergistic effect of the ionic liquid and *** was particularly evident when analyzing various analytes such as organic acids,nucleosides/bases,polycyclic aromatic hydrocarbons(PAHs)and ***,under our operating conditions,an excellent column efficiency of 53,642.9 plates/m was achieved for *** summary,we have proposed a straightforward strategy to enhance the separation performance of hydrogel coatings in liquid chromatography,thereby broadening the potential applications of hydrogels in the field of separation.

关键词： Ionic liquid Hydrogel Functionalized silica Synergistic effect Stationary phase

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