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Phase thermal stability and mechanical properties analyses of(Cr,Fe,V)–(Ta,W)multiple-based elemental system using a compositional gradient film

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International Journal of Minerals,Metallurgy and Materials 2020年第10期27卷 1379-1387页

作者： Qiu-wei xing jiang Ma Yong Zhang Beijing Advanced Innovation Center of Materials Genome Engineering State Key Laboratory of Advanced Metals and MaterialsUniversity of Science and Technology BeijingBeijing 100083China Guangdong Provincial Key Laboratory of Micro/Nano Optomechatronics Engineering College of Mechatronics and Control EngineeringShenzhen UniversityShenzhen 518060China

High-entropy alloys(HEAs)generally possess complex component combinations and abnormal *** traditional methods of investigating these alloys are becoming increasingly inefficient because of the unpredictable phase transformation and the combination of many *** development of compositionally complex materials such as HEAs requires high-throughput experimental methods,which involves preparing many samples in a short *** we apply the high-throughput method to investigate the phase evolution and mechanical properties of novel HEA film with the compositional gradient of(Cr,Fe,V)-(Ta,W).First,we deposited the compositional gradient film by ***,the mechanical properties and thermal stability of the(Cr0.33Fe0.33V0.33)x(Ta0.5W0.5)100−x(x=13-82)multiplebased-elemental(MBE)alloys were *** the deposited wafer was annealed at 600℃for 0.5 h,the initial amorphous phase was transformed into a body-centered cubic(bcc)structure phase when x=*** were observed on the film surface when x was 72 and ***,the highest hardness of as-deposited films was found when x=18,and the maximum hardness of annealed films was found when x=33.

关键词： high-throughput fabrication hard coating thermal resistance mechanical property phase stability high-entropy alloys

Liquisolid technique and its applications in pharmaceutics

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Asian Journal of Pharmaceutical Sciences 2017年第2期12卷 115-123页

作者： mei Lu Haonan xing Jingzheng jiang Xiao Chen Tianzhi Yang Dongkai Wang Pingtian Ding School of Pharmacy Shenyang Pharmaceutical UniversityShenyangChina Department of Basic Pharmaceutical Sciences School of PharmacyHusson UniversityBangorMEUSA

Most of the newly developed drug candidates are lipophilic and poorly water-soluble. Enhancing the dissolution and bioavailability of these drugs is a major challenge for the pharmaceutical industry. Liquisolid technique, which is based on the conversion of the drug in liquid state into an apparently dry, non-adherent, free flowing and compressible powder,is a novel and advanced approach to tackle the issue. The objective of this article is to present an overview of liquisolid technique and summarize the progress of its applications in pharmaceutics. Low cost, simple processing and great potentials in industrial production are main advantages of this approach. In addition to the enhancement of dissolution rate of poorly water-soluble drugs, this technique is also a fairly new technique to effectively retard drug release. Furthermore, liquisolid technique has been investigated as a tool to minimize the effect of pH variation on drug release and as a promising alternative to conventional coating for the improvement of drug photostability in solid dosage forms. Overall, liquisolid technique is a newly developed and promising tool for enhancing drug dissolution and sustaining drug release, and its potential applications in pharmaceutics are still being broadened.

关键词： Liquisolid technique Dissolution enhancement Poorly water-soluble drugs Sustained release pH variation Photostability

Advance in bioequivalence assessment of topica dermatological products

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Asian Journal of Pharmaceutical Sciences 2016年第6期11卷 700-707页

作者： mei Lu Haonan xing Xiao Chen Lei Xian Jingzheng jiang Tianzhi Yang Pingtian Ding School of Pharmacy Shenyang Pharmaceutical UniversityShenyangChina Department of Basic Pharmaceutical Sciences School of PharmacyHusson UniversityBangorMEUSA

Bioequivalence(BE) assessment of topical dermatological products is a long standing challenge. The development of generic topical dermatological products has often been hampered due to the limited number of acceptable approaches, which are capable of determining the BE between generic products and reference list products. The aim of this manuscript is to review different BE assessment approaches of topical dermatological products. Besides, the advances in BE evaluation and biowaivers are also provided. Currently, except in the case of dermatological corticosteroids, the golden rule to establish the BE of most topical dermatological products still heavily relied on clinical endpoint trials,which are often unreliable, time-consuming and expensive. The regulatory agencies and pharmaceutical industries are forging ahead to the development of new surrogate BE assessment approaches for other topical dermatological products. These promising approaches include dermatopharmacokinetic study(DPK), dermal microdialysis(DMD), in vitro studies, pharmacokinetic study(PK), near-infrared spectrometry(NIR), and confocal Raman spectroscopy(CRS). In addition, the expansion of biowaivers for topical dermatological products has been explored by pharmaceutical scientists. In conclusion, to accelerate the development and approval of topical dermatological products, emphasis should be put on the following areas, i.e., optimizing and standardizing the existing BE assessment methods, exploring novel alternatives of BE assessment approaches, and expanding biowaivers for topical dermatological products.

关键词： Bioequivalence assessment Generic Topical dermatological products Biowaiver

Transformation of minerals at the boundary of magma-coal contact zone:case study from Wolonghu Coal Mine, Huaibei Coalfield, China

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International Journal of Coal Science & Technology 2021年第1期8卷 168-175页

作者： xing Chen Liugen Zheng Yalin jiang Chunlu jiang School of Resources and Environmental Engineering Anhui UniversityHefei230601AnhuiChina Anhui Province Engineering Laboratory for Mine Ecological Remediation Hefei230601AnhuiChina

Mesozoic and Cenozoic magma activity in the Wolong Lake mining area of Huaibei is frequent,and the degree of magma intrusion into coal seams *** the one hand,magma intrusion affects the utilization of coal resources;on the other hand,the macro and trace elements in coal are redistributed to form new mineral *** study uses the Wolong Lake magma intrusion coal seam as a research *** mineral paragenesis for igneous rock,coke,and thermally-altered coal in an igneous intrusion zone is studied using SEM,XRD,and Raman *** igneous intrusion,the temperature and pressure of igneous rock metamorphose ambient low-rank coal to high-rank coal and *** response mechanism of minerals and trace elements to magmatic intrusion is *** results are:①SEM analysis shows that ankerite and pyrite are formed from magma *** minerals are strongly developed in the magma-coal contact zone,and less well developed in thermally-altered coal.②XRD analysis shows that igneous intrusion strongly influences the types and content of minerals in coke and thermally-altered *** addition to the increase amounts of ankerite and pyrite,chlorite,serpentine,and muscovite,and other secondary minerals,are generated following igneous intrusion.③Raman analysis suggests that thermally-altered coal possesses the characteristics of both pyrite and *** from the magma-coal boundary zone possesses the typical characteristics of *** rock contains a mineral similar to pyrite,confirmed by both having similar Raman *** scattering intensity of Ag indicates that the formation pressure of pyrite increases from thermally-altered coal via the boundary between the coke zone and the igneous rock.

关键词： Thermally-altered coal Mineral Igneous intrusion Raman spectroscopy

Adverse Effects of Opioid Analgesics in Osteoarthritis Treatment:A Global Meta-Analysis,2000-2022

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China CDC weekly 2024年第25期6卷 589-596,I0001-I0012页

作者： Heng jiang xing xing He Zhu Tuo Dong School of Public Health Harbin Medical UniversityHarbin CityHeilongjiang ProvinceChina School of Public Health Peking UniversityBeijingChina

Osteoarthritis(OA)treatment commonly depends on nonsteroidal anti-inflammatory drugs and opioid ***,the clinical use of opioids is controversial due to their adverse effects and addiction *** study,drawing on 24 randomized controlled trials(RCTs)with a total of 9,586 patients,thoroughly explored the various side effects associated with opioid use in OA *** results provide additional insight into the non-addictive risks of opioids and may assist clinicians in their judicious use,potentially fostering the advancement of safer treatment *** reducing the risks of misuse and addiction,public health and safety can be enhanced.

关键词： potential thoroughly insight

Some geometrical iteration methods for nonlinear equations

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Applied Mathematics(A Journal of Chinese Universities) 2008年第1期23卷 25-30页

作者： LU xing-jiang QIAN Chun Dept. of Math Zhejiang Univ. Hangzhou 310027 China. College of Statist. and Comput. Sci. Zhejiang Gongshang Univ. Hangzhou 310018China.

This paper describes geometrical essentials of some iteration methods （e.g. Newton iteration, secant line method, etc.） for solving nonlinear equations and advances some geometrical methods of iteration that are fle... 详细信息

关键词： nonlinear equation iteration geometric method.

Effect of BaSO_(4) on phase composition and sintering process of iron ore fines

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Journal of Iron and Steel Research International 2022年第3期29卷 408-417页

作者： Jian-tao Ju Chen-mei Tang Guang-heng Ji Xiang-dong xing Gui-qing Zhao Xin-tai jiang Feng-lin Lu School of Metallurgical Engineering Xi’an University of Architecture and TechnologyXi’an710055ShaanxiChina Research Center of Metallurgical Engineering and Technology of Shaanxi Xi’an University of Architecture and TechnologyXi’an710055ShaanxiChina JISCO Iron and Steel Research Institute Jiayuguan735100ShaanxiChina

Iron ore containing BaSO_(4) may have a series of effects on the quality of the sinter and performance of the blast ***,the effect mechanism of BaSO_(4)(0-6.0 mass%)on the compressive strength,mineral composition,and microstructure of the sinter was *** experimental results show that the compressive strength of the sintered samples initially increases and then decreases when the BaSO_(4) content increases from 0 to 6.0 mass%,reaching a peak value of 12.78 kN with a BaSO_(4) content of 1.0 mass%.Thermal analysis indicates that BaSO_(4) initially decomposes to produce BaO at 1468 K in the presence of iron *** combines with Fe_(2)O_(3) forming barium ferrite(Ba_(2)Fe_(6)O_(11)),which exists in the sintered sample with a granular *** also dissolves in calcium ferrite and slag to promote the formation of calcium ferrite and barium glass,*** content of needle-like calcium ferrite gradually increases and then decreases with the increase in BaSO_(4) *** exists in a plate-like *** generation of dicalcium ferrite is promoted by increasing the BaSO_(4) addition from 2.0 to 6.0 mass%.

关键词： Sinter Barium sulfate Hematite Barium ferrite Mineral structure

Are Solar Active Regions Born with Neutralized Currents?

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Research in Astronomy and Astrophysics 2024年第7期24卷 79-88页

作者： Aiying Duan Yaoyu xing Chaowei jiang Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai 519000China Yunnan Key Laboratory of the Solar Physics and Space Science Kunming 650216China Key Laboratory of Tropical Atmosphere-Ocean System Sun Yat-sen UniversityMinistry of EducationZhuhai 519000China Institute of Space Science and Applied Technology Harbin Institute of TechnologyShenzhen 518055China

Solar active regions(ARs)are formed by the emergence of current-carrying magnetic flux tubes from below the *** for an isolated flux tube the direct and return currents flowing along the tube should balance with each other,it remains controversial whether such a neutralization of currents is also maintained during the emergence *** we present a systematic survey of the degrees of the current neutralization in a large sample of flux-emerging ARs which appeared on the solar disk around the central meridian from 2010 to *** vector magnetograms taken by Helioseismic and Magnetic Imager onboard Solar Dynamic Observatory are employed to calculate the distributions of the vertical current density at the *** on the main phase of flux emergence,i.e.,the phase in which the total unsigned magnetic flux is continuously increased,we statistically examined the ratios of direct to return currents in all the *** a large-sample statistical study suggests that most of the ARs were born with currents close to *** degree of current neutralization seems to be not affected by the active-region size,the active-region growing rate,and the total unsigned *** only correlation of significance as found is that the stronger the magnetic field nonpotentiality is,the further the AR deviates from current neutrality,which supports previous event studies that eruption-productive ARs often have non-neutralized currents.

关键词： Sun magnetic fields-Sun flares-Sun corona-Sun coronal mass ejections(CMEs)

Regularity of population occurrence and migration in the oriental armyworm, Mythimna separata(Walker)

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Journal of Integrative Agriculture 2018年第7期17卷 1482-1484页

作者： jiang xing-fu State Key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant Protection Chinese Academyof Agricultural Sciences

The oriental armyworm,Mythimna separata（Walker）（Lepidoptera：Noctuidae）,is a major migrant pest of grain in China and other Asian countries,causing huge crop production and economic losses nationwide *** of the uniquely difficult aspects of managing *** arises from its long-distance migratory *** example,direction and timing of winds from its overwintering regions in the south largely determine where and when large influxes of migrants arrive in the north to oviposit,making prediction of infestations difficult.

关键词： Mythimna separata Regularity of population occurrence and migration in the oriental armyworm Walker