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Interdecadal variation of drought patterns and associated influencing factors in the north-south transitional zone of China

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Journal of Geographical Sciences 2024年第7期34卷 1253-1279页

作者： DONG Qingdong ZHU Lianqi DUAN Zheng WANG Liyuan chen Chaonan LI Yanhong ZHU Wenbo GURUNG Sher Bahadur The College of Geography and Environmental Science Henan UniversityKaifengHenan475004China Department of Physical Geography and Ecosystem Science Lund UniversityLundS-22362Sweden Central Department of Geography Tribhuvan UniversityKathmandu44600Nepal

In the context of global warming,escalating water cycles have led to a surge in drought frequency and ***,multidecadal fluctuations in drought and their multifaceted influencing factors remain inadequately *** study examined the multidecadal changes in drought characteristics(frequency,duration,and severity)and their geographical focal points within China's north-south transitional zone,the Qinling-Daba Mountains(QDM),from 1960 to 2017 using the Standardized Precipitation Evapotranspiration Index(SPEI).In addition,a suite of eight scenarios,correlation analysis,and wavelet coherence were used to identify the meteorological and circulation factors that influenced drought *** results indicate the following:(1)From 1960 to 2017,the QDM experienced significant interdecadal variations in drought frequency,duration,and severity,the climate was relatively humid before the 1990s,but drought intensified ***,the 1990s marked the period of the longest drought duration and greatest severity,while the years spanning 2010 to 2017 experienced the highest frequency of drought events.(2)Spatially,the Qinling Mountains,particularly the western Qinling Mountain,exhibited higher drought frequency,duration,and severity than the Daba *** disparity can be attributed to higher rates of temperature increase and precipitation decrease in the western Qinling Mountain.(3)Interdecadal variations in droughts in the QDM were directly influenced by the synergistic effects of interdecadal fluctuations in air temperature and *** factors modulate temperature and precipitation through phase transitions,thereby affecting drought dynamics in the *** Atlantic Multidecadal Oscillation emerges as the primary circulation factors influencing temperature changes,with a mid-1990s shift to a positive phase favoring *** East Asian Summer Monsoon and El Ni?o-Southern Oscillation are the main circulation factors a

关键词： drought standardized precipitation evapotranspiration index multidecadal shift transitional zone Qinling-Daba Mountains

Initial COVID-19 severity influenced by SARS-CoV-2-specific T cells imprints T-cell memory and inversely affects reinfection

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Signal Transduction and Targeted Therapy 2024年第6期9卷 2791-2803页

作者： Gang Yang Jinpeng Cao Jian Qin Xinyue Mei Shidong Deng Yingjiao Xia Jun Zhao Junxiang Wang Tao Luan Daxiang chen Peiyu Huang cheng chen Xi Sun Qi Luo Jie Su Yunhui Zhang Nanshan Zhong Zhongfang Wang The Affiliated Hospital of Kunming University of Science and Technology.Department of Respiratory and Critical Care Medicine The First People’s Hospital of Yunnan provinceKunmingYunnanChina Guangzhou National Laboratory BiolandGuangzhouGuangdongChina State Key Laboratory of Respiratory Disease&National Clinical Research Center for Respiratory Disease Guangzhou Institute of Respiratory Healththe First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou Medical UniversityGuangzhouChina

The immunoprotective components control COVID-19 disease severity,as well as long-term adaptive immunity maintenance and subsequent reinfection risk discrepancies across initial COVID-19 severity,remain ***,we longitudinally analyzed SARS-CoV-2-specific immune effectors during the acute infection and convalescent phases of 165 patients with COVID-19 categorized by *** found that early and robust SARS-CoV-2-specific CD4^(+)and CD8^(+)T cell responses ameliorate disease progression and shortened hospital stay,while delayed and attenuated virus-specific CD8^(+)T cell responses are prominent severe COVID-19 *** antiviral antibody generation rather than titer level associates with severe ***,initial COVID-19 severity imprints the long-term maintenance of SARS-CoV-2-specific adaptive immunity,demonstrating that severe convalescents exhibited more sustained virus-specific antibodies and memory T cell responses compared to mild/moderate ***,initial COVID-19 severity inversely correlates with SARS-CoV-2 reinfection ***,our study unravels the complicated interaction between temporal characteristics of virus-specific T cell responses and COVID-19 severity to guide future SARS-CoV-2 wave management.

关键词： severity immunity infection

The diagnostic value of tenascin-C in acute aortic syndrome

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Journal of Geriatric Cardiology 2024年第3期21卷 359-368页

作者： Ming MA Wei chen Hai-Long CAO Jun PAN Qing ZHOU Xin-Long TANG Dong-Jin WANG Department of Thoracic and Cardiovascular Surgery Nanjing Drum Tower Hospital Clinical College of Nanjing Medical UniversityNanjingChina Department of Thoracic and Cardiovascular Surgery Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolNanjing UniversityNanjingChina Department of Thoracic surgery Kunshan Hospital of Traditional Chinese MedicineJiangsuChina

OBJECTIVES Misdiagnosis of acute aortic syndrome(AAS)significantly increases ***-C(TN-C)is an extracellular matrix glycoprotein related to cardiovascular *** elevation of TN-C in AAS and whether it can discriminate suddenonset of acute chest pain in Chinese remains *** We measured the plasma concentration of TN-C by ELISA in a cohort of 376 patients with chest or back *** to discriminate AAS from acute coronary syndrome(ACS)were compared and *** From October 2016 to September 2021,376 undiagnosed patients with chest or back pain were enrolled.166 of them were finally diagnosed as AAS,100 were ACS and 110 without cardiovascular diseases(NCV).TN-C was significantly elevated in AAS at 18.18 ng/mL(IQR:13.10–27.68)compared with 7.51 ng/mL(IQR:5.67–11.38)in ACS(P<0.001)and 3.68 ng/mL(IQR:2.50–5.29)in NCV(P<0.001).There was no significant difference in TN-C level among the subtypes of *** the 166 AAS patients,the peaked level of TN-C was at acute stage(P=0.012),then a slight of decrease was observed at subacute *** area under receiver operating characteristic curve for AAS patients versus NCV was 0.979(95%CI:0.964-0.994)for *** a cutoff level of 11.474 ng/mL,TN-C has a sensitivity of 76.0%,specificity of 85.5%,accuracy of 82.0%,positive predictive value(PPV)of 76.0%,negative predictive value(NPV)of 85.5%.Diagnostic performance of TN-C was superior to D-dimer and *** The concentration of serum TN-C in AAS patients was significantly higher than that in ACS patients and ***-C could be a new biomarker to distinguish AAS patients in the early stage after symptoms onset from other pain diseases.

关键词： acute cardiovascular elevated

Dynamic failure process of expanded polystyrene particle lightweight soil under cyclic loading using discrete element method

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Earthquake Engineering and Engineering Vibration 2024年第4期23卷 815-828页

作者： Zhou Wei Hou Tianshun chen Ye Wang Qi Luo Yasheng Zhang Yafei College of Water Resources and Architectural Engineering Northwest A&F UniversityXianyang 712100China Xi’an Key Laboratory of Geotechnical and Underground Engineering Xi’an University of Science and TechnologyXi’an 710054China Hanjiang to Weihe River Valley Water Diversion Project Construction Co. Ltd.Xi’an 710011China

Expanded polystyrene(EPS)particle-based lightweight soil,which is a type of lightweight filler,is mainly used in road *** stability of subgrades under dynamic loading is attracting increased research *** traditional method for studying the dynamic strength characteristics of soils is dynamic triaxial testing,and the discrete element simulation of lightweight soils under cyclic load has rarely been *** study the meso-mechanisms of the dynamic failure processes of EPS particle lightweight soils,a discrete element numerical model is established using the particle flow code(PFC)*** contact force,displacement field,and velocity field of lightweight soil under different cumulative compressive strains are *** results show that the hysteresis curves of lightweight soil present characteristics of strain accumulation,which reflect the cyclic effects of the dynamic *** the confining pressure increases,the contact force of the particles also *** confining pressure can restrain the motion of the particle system and increase the dynamic strength of the *** the confining pressure is held constant,an increase in compressive strain causes minimal change in the contact force between soil ***,the contact force between the EPS particles decreases,and their displacement direction points vertically toward the center of the *** an increase in compressive strain,the velocity direction of the particle system changes from a random distribution and points vertically toward the center of the *** the compressive strain is 5%,the number of particles deflected in the particle velocity direction increases significantly,and the cumulative rate of deformation in the lightweight soil ***,it is feasible to use 5%compressive strain as the dynamic strength standard for lightweight *** element methods provide a new approach toward the dynamic performance evaluation of lightw

关键词： lightweight soil cyclic loading dynamic triaxial test discrete element method hysteresis curve

microRNA-2184 orchestrates Mauthner-cell axon regeneration in zebrafish via syt3 modulation

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Journal of Genetics and Genomics 2024年第9期51卷 911-921页

作者： xinghan chen Yueru Shen Zheng Song Xinliang Wang Huaitong Yao Yuan Cai Zi-Ang Zhao Bing Hu Hefei National Research Center for Physical Sciences at the Microscale University of Science and Technology of ChinaHefeiAnhui 230026China The First Affiliated Hospital of USTC Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230026China Center for Advanced Interdisciplinary Science and Biomedicine of IHM Division of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui 230026China

MicroRNAs(miRNAs)play a significant role in axon regeneration following spinal cord ***,the functions of numerous miRNAs in axon regeneration within the central nervous system(CNS)remain largely ***,we elucidate the positive role of microRNA-2184(miR-2184)in axon regeneration within zebrafish Mauthner cells(M-cells).The upregulation of miR-2184 in a single M-cell can facilitate axon regeneration,while the specific sponge-induced silencing of miR-2184 leads to impeded *** show that syt3,a downstream target of miR-2184,negatively regulates axon regeneration,and the regeneration suppression modulated by syt3 depends on its binding to Ca2+.Furthermore,pharmacological stimulation of the cAMP/PKA pathway suggests that changes in the readily releasable pool may affect axon *** data indicate that miR-2184 promotes axon regeneration of M-cells within the CNS by modulating the downstream target syt3,providing valuable insights into potential therapeutic strategies.

关键词： Axon regeneration Axon ablation miR-2184 syt3 Readily releasable pool

Early Triassic Legoupil Formation in Schmidt Peninsula,Antarctic Peninsula:Provenance and Depositional Settings

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Journal of Earth Science 2024年第2期35卷 317-331页

作者： Chao Zhang Ying-Chun Cui chen-Guang Liu Fang-Hua Cui Lu-Yuan Wang Wei-Qiang Zhang School of Resources and Environmental Engineering Shandong University of TechnologyZibo255049China MNR Key Laboratory for Polar Science Polar Research Institute of ChinaShanghai201209China Key Laboratory of Marine Sedimentology and Environmental Geology First Institute of OceanographyState Oceanic AdministrationQingdao266061China Laboratory for Marine Geology Qingdao National Laboratory for Marine Science and TechnologyQingdao266061China Key Laboratory of Mineral Resources Evaluation in Northeast Asia Ministry of Land and ResourcesChangchun130061China

Geochemical compositions can be used to determine the tectonic setting of sedimentary basins,while where the link of source to sink is no longer preserved,detrital zircon age patterns can aid in resolving the original basin *** metasedimentary Legoupil Formation,located at Cape Legoupil and the Schmidt Peninsula,could give a hint for the tectonic evolution of Antarctic *** this contribution,we constrain the sedimentary provenance of the Legoupil Formation through geochemistry and detrital zircon U-Pb *** petrography and geochemical features indicate that the provenance of the Legoupil Formation could be felsic *** zircon grains record a steady supply of Permian and Ordovician material into the Legoupil *** youngest concordant zircon ages of 262 Ma suggest that the depositional time of Legoupil Formation is no older than Late *** detrital zircon age spectrum of Legoupil Formation suggests that the Legoupil Formation sediments should be derived from regional sources endemic to western Gondwana prior to its *** with the previous studies,geochemistry and detrital zircons reflect an active continental margin tectonic setting and the detrital zircon spectra of Legoupil Formation are similar to the ones deposited in forearc tectonic setting.

关键词： Schmidt Peninsula Legoupil Formation Trinity Peninsula Group detrital zircons Antarctic Peninsula geochemistry

Application of artificial synapse based on all-inorganic perovskite memristor in neuromorphic computing

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Nano Materials Science 2024年第1期6卷 68-76页

作者： Fang Luo Wen-Min Zhong Xin-Gui Tang Jia-Ying chen Yan-Ping Jiang Qiu-Xiang Liu School of Physics&Optoelectric Engineering Guangdong University of TechnologyGuangzhou Higher Education Mega CenterGuangzhou510006China

Artificial synapse inspired by the biological brain has great potential in the field of neuromorphic computing and artificial *** memristor is an ideal artificial synaptic device with fast operation and good ***,we have prepared a memristor device with Au/CsPbBr_(3)/ITO *** memristor device exhibits resistance switching behavior,the high and low resistance states no obvious decline after 400 switching *** memristor device is stimulated by voltage pulses to simulate biological synaptic plasticity,such as long-term potentiation,long-term depression,pair-pulse facilitation,short-term depression,and short-term *** transformation from short-term memory to long-term memory is achieved by changing the stimulation *** addition,a convolutional neural network was constructed to train/recognize MNIST handwritten data sets;a distinguished recognition accuracy of~96.7%on the digital image was obtained in 100 epochs,which is more accurate than other memristor-based neural *** results show that the memristor device based on CsPbBr3 has immense potential in the neuromorphic computing system.

关键词： Memristor CsPbBr_(3) Resistive switching Artificial synapse Neuromorphic computing

A new bio-oxidation method for removing iron deposits from waterlogged wood of Nanhai I shipwreck,Guangdong,China

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Engineering Microbiology 2024年第1期4卷 1-9页

作者： Yishu Wang Zijun Zhao Jianqun Lin Qinglin Ma Linxu chen International Joint Research Laboratory of Environmental and Social Archaeology Shandong UniversityQingdao 266237China State Key Laboratory of Microbial Technology Shandong UniversityQingdao 266237China

The widespread presence of iron and sulfur compounds such as pyrite in marine waterlogged archeological wood(WAW)can cause irreversible damage to the safety of its *** issue has been a longstanding concern for cultural heritage conservation *** this study,we examined the distribution and phase composition of Fe and sulfur compounds in wood samples obtained from the Nanhai I shipwreck using ESEM-EDS,micro-Raman spectroscopy,and an X-ray *** removal of iron from WAW samples of the Nanhai I shipwreck using Acidithiobacillus ferrooxidans(***)was evaluated using conductivity and ICP-AES *** results showed that *** effectively improved the removal of iron from *** degradation of fresh healthy wood during treatment was also analyzed using infrared spectroscopy,and the results showed that the treatment had little effect on the samples over a short *** study demonstrates,for the first time,the feasibility of iron extraction from marine WAW by *** was also the first attempt in China to apply biological oxidation to the removal of iron from marine archeological materials.

关键词： Waterlogged archeological wood Iron-sulfur compounds Acidithiobacillus ferrooxidans Cultural heritage

The RFI Fast Mitigation Algorithm Based on Block LMS Filter

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Research in Astronomy and Astrophysics 2024年第1期24卷 265-272页

作者： Han Wu Hai-Long Zhang Ya-Zhou Zhang Jie Wang Xu Du Ting Zhang Xin-chen Ye Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Radio Astronomy Chinese Academy of SciencesNanjing 210008China National Astronomical Data Center Beijing 100101China

The radio telescope possesses high sensitivity and strong signal collection *** receiving celestial radiation signals,it also captures Radio Frequency Interferences(RFIs)introduced by human ***,as signals originating from sources other than the astronomical targets,significantly impacts the quality of astronomical *** paper presents an RFI fast mitigation algorithm based on block Least Mean Square(LMS)*** enhances the traditional adaptive LMS filter by grouping L adjacent time-sampled points into one block and applying the same filter coefficients for filtering within each *** transformation reduces multiplication calculations and enhances algorithm efficiency by leveraging the time-domain convolution *** algorithm is tested using baseband data from the Parkes 64 m radio telescope's pulsar observations and simulated *** results confirm the algorithm's effectiveness,as the pulsar profile after RFI mitigation closely matches the original pulsar profile.

关键词： methods:data analysis techniques:interferometric (stars:)pulsars:individual(J0437-4715)