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Danhong Injection Improves Elective Percutaneous Coronary Intervention in UA Patients with Blood Stasis Syndrome Revealed by Perioperative Metabolomics

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World Journal of Traditional Chinese Medicine 2022年第2期8卷 247-256页

作者： Qian Niu Wen-long xing Yu-Tong Wang Yan zhu Hong-Xu Liu Department of Critical Care Medicine Zhuhai Hospital of Guangdong Provincial Hospital of Traditional Chinese MedicineZhuhaiChina Department of Cardiology Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijingChina Department of Traditional Chinese Medicine Capital Medical UniversityBeijingChina State Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese MedicineTianjinChina

Objective:To observe the effect of Danhong injection(DHI)on perioperative metabolomics of unstable angina pectoris(UA)with blood stasis *** and Methods:A prospective,randomized,controlled,and single-blind clinical trial was ***-one UA patients with traditional Chinese medicine blood stasis syndrome undergoing elective percutaneous coronary intervention(PCI)were randomly divided into the Danhong and control groups,and 10 healthy volunteers were included as *** Danhong group received western medicine+DHI treatment,while the control group received western medicine+*** metabolomics was used to analyze the serum metabolites of healthy volunteers in the Danhong and control groups before and 5 days after ***:Before treatment,there was no significant difference in serum metabolites between the Danhong and control groups,but there was a significant difference between the two groups and the healthy *** metabolites were clustered mainly in glycerophospholipid,sphingolipid,purine,and amino acid groups,which were generated in their metabolic *** 5 days of PCI,the profiles of serum metabolites were significantly closer between the Danhong-or control-treated groups and that of the healthy ***,DHI treatment converted the serum metabolite profile more to that of the healthy group than the control ***:The beneficial effect of DHI on patients with unstable angina is reflected at the level of serum metabolic biomarkers.

关键词： Danhong injection metabolomics perioperative percutaneous coronary intervention unstable angina pectoris

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The temperature of IGM at high redshifts:shock heating and high mach problem

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Research in Astronomy and Astrophysics 2020年第6期20卷 253-264页

作者： Jun-Yi Jia Wei-Shan zhu Liang Gao long-long Feng Key Laboratory for Computational Astrophysics National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Science University of Chinese Academy of SciencesBeijing 100049China School of Physics and Astronomy Sun Yat-Sen UniversityZhuhai 519082China Institute of Computational Cosmology Department of PhysicsUniversity of DurhamSouth RoadDurham DH13LEUK 5 Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210008China

The thermal history of cosmic gas in the dark ages remains largely *** is important to quantify the impact of relevant physics on the IGM temperature between z=10 and z^30,in order to interpret recent and oncoming observations,including results reported by *** revisit the gas heating due to structure formation shocks in this era,using a set of fixed grid cosmological hydrodynamical simulations performed by three different *** all our simulations,the cosmic gas is predicted to be in multiphase state since z>*** gas surrounding high density peaks gradually develops a relation more sharp than T∝ρ2/3,approximately T∝ρ2,from z=30 to z=11,might be due to shock ***,the gas in void region tends to have a large local Mach number,and their thermal state varies significantly from code to *** the redshift range 11-20,the mass fraction of gas shock heated above the CMB temperature in our simulations is larger than previous semi-analytical results by a factor of 2 to *** z=15,the fraction varies from^19%to 52%among different *** z=11 and z=20,the gas temperatureM-1 is predicted to be^10-20 K by two codes,much higher than the adiabatic cooling model and some previous ***,in our simulations performed by RAMSES,M-1is predicted to be even below the temperature required to explain result of the *** the fact that different codes give different predictions,currently,it seems a challenge to make solid prediction on the temperature of gas at z^17 in simulations.

关键词： cosmology theory-dark ages,reionization,first stars-galaxies high-redshift-intergalactic medium

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Pathophysiological mechanisms of chronic compressive spinal cord injury due to vascular events

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Neural Regeneration Research 2023年第4期18卷 790-796页

作者： Zhen-Xiao Ren Jing-Hui Xu xing Cheng Gui-xing Xu Hou-Qing long Guangdong Provincial Key Laboratory of Orthopaedics and Traumatology/Department of Spine Surgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Neurosurgery The First Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Cervical spondylotic myelopathy is the main cause of non-traumatic spinal cord injury,with chronic static and/or dynamic compressive spinal cord injury as the unique *** the progression of this condition,the microvascular network is compressed and destroyed,resulting in ischemia and *** main pathological changes are inflammation,damage to the blood spinal cord barriers,and cell apoptosis at the site of *** have confirmed that vascular regeneration and remodeling contribute to neural repair by promoting blood flow and the reconstruction of effective circulation to meet the nutrient and oxygen requirements for nerve *** decompression is the most effective clinical treatment for this condition;however,in some patients,residual neurological dysfunction remains after *** revascularization during compression and after decompression is therefore complementary to surgical *** this review,we summarize the progress in research on chronic compressive spinal cord injury,covering both physiological and pathological changes after compression and decompression,and the regulatory mechanisms of vascular injury and repair.

关键词： angiogenesis cervical spondylotic myelopathy hypoxia inflammation ischemia spinal cord injury surgical decompression

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Study on HOBEM Based on Analytical Panel Integrals Related to Translating-Pulsating Source for Hydrodynamic Responses of Vessels Sailing in Waves

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China Ocean Engineering 2022年第3期36卷 348-362页

作者： YANG Yun-tao zhu Ren-chuan LI Yu-long School of Naval Architecture and Civil Engineering Jiangsu University of Science and TechnologyZhangjiagang 215600China State Key Laboratory of Ocean Engineering Collaborative Innovation Center for Advanced Ship and Deep-Sea ExplorationSchool of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai 200240China Technology Centre for Offshore and Marine Singapore(TCOMS)Singapore

A higher-order boundary element method(HOBEM)incorporated with analytical panel integrals related to translat-ing-pulsating source Green’s function is proposed for the hydrodynamic response prediction of ships advancing in *** this method,the 9-node bi-quadratic curvilinear elements employed to discretize the mixed-source/dipole boundary integral equation are mapped into the parametric plane through a coordinate *** in order to ease the numerical instability problem,a novel analytical quadrature is derived to calculate the influence coefficients by changing the integral order and using integration by *** singularity caused by infinite discontinuity is analyzed and eliminated by adopting some mathematical *** the calculations of panel integrals of Green’s function and its x-derivative,the analytical integral method is proved to be always accurate even for field points approaching the free surface,where numerical quadrature is impossible to give reasonable *** on this,a higher-order seakeeping program is developed and applied in the motion response prediction of two different types of ships(i.e.,a wall-sided ship Wigley III and a non-wall-sided ship S175).By comparing the computed results with the corresponding experimental data and numerical solutions of the translating-pulsating and higher-order Green’s function methods based on traditional Gauss quadrature,it is found that the HOBEM based on analytical quadrature is of better accuracy and *** the non-wall-sided ship,only the present method can produce reasonable pre-diction of motion responses,while obvious oscillatory phenomenon is observed in the results of the other two numerical methods based on Gauss quadrature.

关键词： HOBEM translating-pulsating Green’s function analytical quadrature seakeeping forward speed

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A Theoretic Model for the Shock Observed in Geo-space

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Communications in Theoretical Physics 2005年第5期43卷 923-926页

作者： SHIJian-Kui WANGXiao ZHANGTie-long TorkarKlaus LIUZhen-xing CenterforSpaceScienceandAppliedResearch theChineseAcademyofSciencesBeijing100080China SpaceResearchInstitute AustrianAcademyofSciencesA-8010GrazAustria

An electrostatic model for the shock observed in the earth's polar region is established by deriving the 'Sagdeev potential' from the magnetohydrodynamic equations in a cylindrical coordinate system. The results show that the shock can develop from the ion acoustic wave or ion cyclotron wave in the polar region, and can exist when the Mach number M and the initial electric field E-0 satisfy the condition of vertical bar(a/M-2-1)E(0)vertical bar = 1. Also, some features of the shock wave are discussed. The result can interpret the electrostatic shock observed in the earth's polar region.

关键词： magnetohydrodynamics shock wave polar ionosphere

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Antitumor and antimicrobial activities of endophytic fungi from medicinal parts of Aquilaria sinensis

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2011年第5期12卷 385-392页

作者： Jin-long CUI Shun-xing GUO Pei-gen XIAO Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical College Beijing 100193 China

The purpose of this study was to isolate and characterize endophytic fungi from the stem tissue which can produce fragrant ingredients in Aquilaria sinensis(also called agarwood) to determine their antitumor and antimicrobial ***-eight fungal endophytes were isolated from agarwood by strict sterile sample preparation and were classified into 14 genera and 4 taxonomic classes(Sordariomycetes,Dothideomycetes,Saccharomycetes,and Zy-gomycetes) based on molecular *** the 28 isolates,13(46.4%) showed antimicrobial activity against at least one of the test strains by the agar well diffusion method,and 23 isolates(82.1%) displayed antitumor activity against at least one of five cancer cell lines by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT) *** diameters of inhibition zones of YNAS07,YNAS14,HNAS04,HNAS05,HNAS08,and HNAS11 were equal to or higher than 14.0 mm against Staphylococcus aureus,Escherichia coli,Bacillus subtilis,***,Aspergillus fumigatus,and ***,*** inhibition rates of YNAS06,YNAS08,and HNAS06 were not less than 60% to 293-T,293-T,and SKVO3 cells,*** results suggest that the endophytic fungi associated with agarwood will provide us with not only useful micro-ecological information,but also potential antimicrobial and anti-tumor agents.

关键词： Agar diffusion method Agarwood Antimicrobial bioactivity Antitumor bioactivity Endophytic fungi

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Influence of Al on the magnetostriction of Fe-Ga polycrystal alloys under compressive stress

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International Journal of Minerals,Metallurgy and Materials 2014年第1期21卷 52-57页

作者： long-long Liao Mei-ling Fang Jie zhu Ji-heng Li Jian Wang State Key Laboratory for Advanced Metals and Materials University of Science and Technology Beijing

Fe80Ga20-xAlx （x = 0, 6, 9, 14） ingots were prepared from high purity elements using a vacuum induction system. X-ray diffraction patterns show that the alloys are A2 disordered structures. The influence of the partial substitution of Ga in Fe-Ga alloys with A1 on their magnetostrictive properties was investigated, and the effects of different heat treatment conditions on the magnetostriction and microstructure of the alloy rods were also examined. The saturation magnetostriction value of FesoGa2o can reach to 240 x 10-6 under a compressive stress of 20 MPa. The Fe80GallA19 alloy has many good properties, such as low hysteresis, high linearity of the magnetostriction curve, and low saturated magnetic field, which make it a potential candidate for magnetostrictive actuator and transducer applications. It is found that subgrains have little influence on the magnetostriction of Fe-Ga alloys.

关键词： iron-gallium alloys polycrystals aluminum magnetostriction compressive stress

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Effectiveness of Fiber Bragg Grating monitoring in the centrifugal model test of soil slope under rainfall conditions

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Journal of Mountain Science 2017年第5期14卷 936-947页

作者： LI long-qi JU Neng-pan GUO Yong-xing State Key Laboratory of Geohazard Prevention and Geoenvironment Protection Chengdu University of Technology Chengdu 610059 China College of Environment and Civil Engineering Chengdu University of Technology Chengdu 610059 China School of Machinery and Automation Wuhan University of Science and Technology Wuhan 430081 China

Centrifugal model testsare playing an increasingly importantrolein investigating slope characteristics under rainfall conditions. However, conventional electronic transducers usually fail during centrifugal model tests because of the impacts of limitedtest space, high centrifugal force, and presence of water, with the result that limited valid data is obtained. In this study, Fiber Bragg Grating(FBG) sensing technology is employed in the design and development of displacement gauge, an anchor force gauge and an anti-slide pile moment gauge for use on centrifugal model slopes with and without a retaining structure. The two model slopes were installed and monitored at a centrifugal acceleration of 100 g. The test results show that the sensors developed succeed in capturing the deformation and retaining structure mechanical response of the model slopes during and after rainfall. The deformation curvefor the slope without retaining structure shows a steepresponse that turns gradualfor the slope with retaining structure. Importantly, for the slope with the retaining structure, results suggest that more attention be paid to increase of anchor force and antislide pile moment during rainfall. This study verifies the effectiveness of FBG sensing technology in centrifuge research and presents a new and innovative method for slope model testing under rainfall conditions.

关键词： Fiber Bragg Grating sensing technology Centrifugal model test Soil slope Rainfall conditions Slope displacement

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Adsorption of catechol from aqueous solution by aminated hypercrosslinked polymers

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Journal of Environmental Sciences 2005年第4期17卷 584-588页

作者： SUNYue LIXiao-tao XUChao CHENJin-long LIAi-min ZHANGQuan-xing StateKeyLaboratoryofPollutionControlandResourcesReuse SchooloftheEnvironmentNanjingUniversityNanjing210093China.

Adsorption of catechol from aqueous solution with the hypercrosslinked polymeric adsorbent NDA-100 and its derivatives AH-1, AH-2 and AH-3 aminated by dimethylamine, the commercial resin Amberlite XAD-4 and weakly basic anion exchanger resin D301 was compared. It was found that the aminated hypercrosslinked resins had the highest adsorption capacities among the tested polymers. The empirical Freundlich equation was successfully employed to describe the adsorption process. Specific surface area and micropore structure of the adsorbent, in company with tertiary amino groups on matrix affected the adsorption performance towards catechol. In addition, thermodynamic study was carried out to interpret the adsorption mechanism. Kinetic study testified that the tertiary amino groups on the polymer matrix could decrease the adsorption rate and increase the adsorption apparent activation energy.

关键词： hypercrosslinked polymer catechol adsorption thermodynamics kinetics

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Effects of Ce on catalytic combustion of methane over Pd-Pt/Al_2O_3 catalyst

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Journal of Environmental Sciences 2012年第3期24卷 507-511页

作者： xing Fan Fan Wang Tianle zhu Hong He School of Chemistry and Environment Beihang UniversityBeijing 100191China College of Environmental and Energy Engineering Beijing University of TechnologyBeifing 100124China

Activity and stability of 1%Pd-0.2%Pt/Al2O3 and 1%Pd-0.2%Pt/0.6%Ce/Al2O3 catalysts prepared by impregnation method for catalytic combustion of methane in air were investigated. The catalysts before and after reaction were characterized by BET, CO chemisorption, XRD and XPS techniques. Results showed that the presence of Ce significantly increased the activity and thermal stability of the Pd-Pt/Al2O3 catalyst towards methane combustion, which could be attributed to more highly-dispersed active PdO particles over the Pd-Pt/Ce/Al2O3 catalyst surface as well as the retarded sintering of PdO and the maintained oxidized state of surface Pd during the combustion process in the presence of Ce.

关键词： catalytic combustion methane Pd-Pt/Ce/Al2O3 catalyst stability metal dispersion

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