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港口重载AGV驱动防滑设计

机械设计 2024年第5期41卷 54-59页

作者：孙凌宇王子航刘璇张桐瑞李鑫宝河北工业大学机械工程学院天津300401

针对港口重载自动导引运输车(AGV)工作中遇到的过度滑转危险,文中提出一种基于最佳滑转率控制的驱动防滑设计。该设计根据港口环境特点建立路面附着特性模型;选用T-S型模糊控制器进行港口路面模糊识别设计,对峰值纵向附着系数及最佳滑... 详细信息

针对港口重载自动导引运输车(AGV)工作中遇到的过度滑转危险,文中提出一种基于最佳滑转率控制的驱动防滑设计。该设计根据港口环境特点建立路面附着特性模型;选用T-S型模糊控制器进行港口路面模糊识别设计,对峰值纵向附着系数及最佳滑转率进行识别,并将识别结果用于最佳滑转率控制中,进而提升港口AGV驱动防滑性能。通过单一路面与对接路面识别试验,验证了港口路面模糊识别器具有准确识别能力。

关键词：港口重载AGV 驱动防滑设计 T-S型路面模糊识别器最佳滑转率

基于生物信息学及动物实验对芪黄固肾通络方治疗糖尿病肾病的研究

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世界中医药 2024年第5期19卷 615-622页

作者：李新宝庞欣欣彭紫凝商海涛朱清郑威韩佳瑞河南中医药大学第二临床医学院郑州450046 河南省中医院郑州450002

目的:探讨芪黄固肾通络方治疗糖尿病肾病(DKD)的作用机制。方法:通过人类基因数据库(GeneCards)、治疗靶点数据库(TTD)、人类疾病相关基因和突变基因数据库(DisGeNET)、综合性药物数据库(DrugBank)等数据库查找芪黄固肾通络方的活性成... 详细信息

目的:探讨芪黄固肾通络方治疗糖尿病肾病(DKD)的作用机制。方法:通过人类基因数据库(GeneCards)、治疗靶点数据库(TTD)、人类疾病相关基因和突变基因数据库(DisGeNET)、综合性药物数据库(DrugBank)等数据库查找芪黄固肾通络方的活性成分、作用靶点、DKD相关的靶点。将药物目标点与病变靶点进行映射,将所获得的交集目标点构造蛋白质-蛋白质相互作用(PPI)网络与活性组分-联合目标网络,并进行基因本体(GO)和京都基因与基因组百科全书(KEGG)富集分析。通过动物实验对网络药理学结果中芪黄固肾通络方治疗糖尿病肾病核心靶点中富集节点较多的前3靶点进行验证。选取C57BL/6J小鼠为研究对象,链脲佐菌素(STZ)连续2次腹腔注射制备动物模型,8周后测小鼠24 h尿蛋白定量,分为正常组、模型组、模型+芪黄固肾通络方组,干预8周后,测胰岛素、C肽、尿素氮、24 h尿蛋白定量,qPCR及蛋白质印迹法(Western Blotting)检测小鼠肾脏CTNNB1、JUN、NCOA1表达。结果:GO与KEGG富集分析显示芪黄固肾通络方治疗DKD的有效靶点主要涉及晚期糖基化终末产物-晚期糖基化终末产物受体(AGE-RAGE)信号通路、血脂和动脉粥样硬化、流体剪切应力与动脉粥样硬化、神经活性配体-受体交互作用等;动物实验表明,芪黄固肾通络方能够降低DKD小鼠肾组织中连环蛋白β1(CTNNB1)、JUN、核受体辅激活蛋白1(NCOA1)的信使核糖核酸(mRNA)及蛋白表达,改善肾脏损伤。结论:通过网络药理学和实验验证,发现芪黄固肾通络方可能通过降低CTNNB1、JUN、NCOA1蛋白的表达水平干预AGE-RAGE等通路治疗DKD。

关键词：芪黄固肾通络方糖尿病肾病网络药理学动物实验晚期糖基化终末产物-晚期糖基化终末产物受体连环蛋白β JUN 核受体辅激活蛋白1

Defect-modulated and heteroatom-functionalized Ti_(3−x)C_(2)T_(y)MXene 3D nanocavities induce growth of MoSe_(2)nanoflakes toward electrocatalytic hydrogen evolution in all pH electrolytes

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Nano Research 2024年第7期17卷 6294-6304页

作者： Ming Du Xianzhi Yang Jian Zhang Wei Chen Huajie Huang xinbao Zhu Xing’ao li State Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials(IAM) Jiangsu National Synergetic Innovation Centre for Advanced Materials(SICAM)Nanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023China College of Electronic and Optical Engineering and College of Flexible Electronics Nanjing University of Posts and Telecommunications(NJUPT) Nanjing 210023China New Energy Technology Engineering Lab of Jiangsu Province College of ScienceNanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023China College of Pharmaceutical and Chemical Engineering Taizhou UniversityJiaojiang 318000China College of Mechanics and Materials Hohai UniversityNanjing 210098China College of Chemical Engineering Nanjing Forestry UniversityNanjing 210037China

Reducing kinetic energy barriers and developing accessible active sites are critical to deliver high hydrogen evolution reaction(HER)*** this paper,we synthesized defect-modulated and heteroatom(boron)-functionalized three-dimensional(3D)bowl-shaped Ti_(3−x)C_(2)T_(y)MXene(B-TCT)nanocavities coupled with the vertical growth of MoSe_(2)*** B-TCT@MoSe_(2)nanohybrids catalyst delivers the overpotentials of 49.9,52.7,and 67.8 mV to reach a HER current density of 10 mA·cm^(−2)under acidic,alkaline,and neutral conditions,*** outstanding HER activity is predominantly attributed to the heteroatom functionalization,self-adapting Ti vacancy(VTi)defect modulation,and spatial configuration design in the 3D B-TCT nanocavity,which synergistically regulate the electronic structure,activate the basal plane/edge unsaturated sites,and reduce the reaction energy *** and theoretical calculations demonstrate that strong heterogeneous interfacial bonding interactions between B-TCT and MoSe_(2)can dramatically reduce the free energy of hydrogen adsorption and facilitate efficient interfacial charge migration,thus essentially improving the HER *** used this 3D porous nanohybrid system assembled by defectrich lamellar structures to elucidate the advantageous synergistic effects of multiple mechanisms among defect structure,heteroatom functionalization,and interfacial coupling,which provided important insights for the development of efficient hybridtype catalysts.

关键词： electrocatalytic H_(2)evolution three-dimensional(3D)MXene nanocavity MoSe_(2)nanoflake self-adapting Ti vacancy defect heteroatom-functionalized interfacial interaction

Dendrite morphology and evolution mechanism of nickel-based single crystal superalloys grown along the<001>and<011>orientations

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Progress in Natural Science:Materials International 2012年第5期22卷 407-413页

作者： Chubin Yang,lin liu n,xinbao Zhao,Yafeng li,Jun Zhang,Hengzhi Fu State Key Laboratory of Solidification Processing,Northwestern Polytechnical University,Xi’an 710072,China State Key Laboratory of Solidification Processing Northwestern Polytechnical University Xi'an 710072 China

Nickel-based single crystal superalloys oriented along the and lattice directions were produced by a bottom seeding technique in an attempt to understand the evolution mechanism of the dendrite grown along different orientations in the present *** changes in primary dendrite arm spacing for single crystal with different orientations are also *** was found that the dendrite morphologies of single crystal superalloy grown along were different from that of .Firstly,the dendrites showed the irregular cruciforms and array in rows in a transverse ***,no typical primary dendrites were observed but the dendrite morphologies appeared like the letter "V" or "W" in a longitudinal *** primary dendrite arms grew along the orientation from the bottom of the sample in the ***,in the orientation,the single crystal developed by continuous side-branching along the [001] and [010] *** primary dendrite arm spacing was as the function of the deviation angle φ.It indicates that with the increase in the deviation angle φ,the primary dendrite arm spacing first increased,and then decreased.

关键词： Dendrite morphology Directional solidification Single crystal superalloy Crystal orientation

Effect of magnetism on the adsorption of methylene blue using engineered biochar pyrolyzed from agricultural waste

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Effect of magnetism on the adsorption of methylene blue usin...

Boosting Electrochemical Urea Synthesis via Constructing Ordered Pd–Zn Active Pair

河南省化学会2016年学术年会

作者： Guoting li Mingju Wang Bingtao liu xinbao li Yiping Guo Department of Environmental and Municipal Engineering North China University of Water Resources and Electric Power

Agricultural waste is a realistic source for synthesizing low-cost adsorbent. Recently attention has been paid to the utilization and application of biochar, which is derived from the biomass via inco

关键词： magnetism biochar adsorption agricultural waste

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Nano-Micro Letters 2024年第11期16卷 529-540页

作者： Weiliang Zhou Chao Feng Xuan li Xingxing Jiang lingyan Jing Shuai Qi Qihua Huo Miaoyuan Lv xinbao Chen Tianchi Huang Jingwen Zhao Na Meng Hengpan Yang Qi Hu Chuanxin He College of Chemistry and Environmental Engineering Shenzhen UniversityShenzhen 518060GuangdongPeople’s Republic of China School of Chemistry and Chemical Engineering/State Key Laboratory Incubation Base for Green Processing of Chemical Engineering Shihezi UniversityShihezi 832003XinjiangPeople’s Republic of China

Electrochemical co-reduction of nitrate(NO_(3)^(-))and carbon dioxide(CO_(2))has been widely regarded as a promising route to produce urea under ambient conditions,however the yield rate of urea has remained ***,we report an atomically ordered intermetallic pallium-zinc(PdZn)electrocatalyst comprising a high density of PdZn pairs for boosting urea *** is found that Pd and Zn are responsible for the adsorption and activation of NO_(3)^(-)and CO_(2),respectively,and thus the co-adsorption and co-activation NO_(3)^(-)and CO_(2) are achieved in ordered PdZn *** importantly,the ordered and well-defined PdZn pairs provide a dual-site geometric structure conducive to the key C-N coupling with a low kinetical barrier,as demonstrated on both operando measurements and theoretical ***,the PdZn electrocatalyst displays excellent performance for the co-reduction to generate urea with a maximum urea Faradaic efficiency of 62.78%and a urea yield rate of 1274.42μg mg^(-1) h^(-1),and the latter is 1.5-fold larger than disordered pairs in PdZn *** work paves new pathways to boost urea electrosynthesis via constructing ordered dual-metal pairs.

关键词： Electrochemical C-N coupling Urea electrosynthesis Intermetallic compounds Geometric structures Active pairs

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生物质合成甲醇的热力学性质研究

太阳能学报 2009年第2期30卷 256-260页

作者：朱灵峰杜磊李新宝李国亭华北水利水电学院郑州450011

采用热化学方法,将玉米秸秆裂解为生物质燃气,制备出甲醇合成气;在C301铜基催化剂的作用下,在直流流动等温积分反应器中,对玉米秸秆合成气催化合成甲醇进行了试验研究。运用SHBWR状态方程,计算了加压下秸秆合成气合成甲醇反应体系的密... 详细信息

采用热化学方法,将玉米秸秆裂解为生物质燃气,制备出甲醇合成气;在C301铜基催化剂的作用下,在直流流动等温积分反应器中,对玉米秸秆合成气催化合成甲醇进行了试验研究。运用SHBWR状态方程,计算了加压下秸秆合成气合成甲醇反应体系的密度及状态方程参数;在一定温度和压力条件下,计算了不同组成秸秆合成气合成甲醇反应体系的总反应热△H_(T,P)、平衡常数K_(f_1)、K_(f_2)、K_(p_1)、K_(p_2)及平衡体系各组分的浓度,为生物质(秸秆)气催化合成甲醇工业设备的设计提供了基础研究数据。

关键词：生物质秸秆合成气甲醇反应热平衡常数

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开拓临床肿瘤实践前沿创建腹膜肿瘤学科

中国肿瘤临床 2020年第3期47卷 109-113页

作者：姬忠贺李鑫宝于洋闫风彩李雁首都医科大学附属北京世纪坛医院腹膜肿瘤外科(北京市肿瘤深部热疗与全身热疗技术培训基地) 北京市100038 首都医科大学附属北京世纪坛医院病理科(北京市肿瘤深部热疗与全身热疗技术培训基地) 北京市100038

腹膜种植转移是恶性肿瘤三大转移途径之一,也是临床肿瘤学长期认识不足、诊治技术水平落后的“老、大、难”问题。近30年,腹膜种植转移外科整合诊治技术体系的建立、完善和推广,引领了肿瘤腹膜转移基础、转化和临床研究热潮,推动形成了... 详细信息

腹膜种植转移是恶性肿瘤三大转移途径之一,也是临床肿瘤学长期认识不足、诊治技术水平落后的“老、大、难”问题。近30年,腹膜种植转移外科整合诊治技术体系的建立、完善和推广,引领了肿瘤腹膜转移基础、转化和临床研究热潮,推动形成了腹膜肿瘤学学科雏形,填补了临床肿瘤学的空白。基于对腹膜转移肿瘤生物学规律、特点和机制的深入认识,腹膜肿瘤临床诊断学、治疗学核心技术体系初步建成并逐渐完善,诞生了高级别循证医学证据导向的“十大里程碑”事件。2012年,《中国肿瘤临床》首推“腹膜转移癌专栏”,引领国内肿瘤学界着力研究腹膜癌诊治策略。8年来,在中国抗癌协会的大力支持下,我国腹膜肿瘤学专家协同努力,逐步完善了中国特色的腹膜癌综合诊疗技术体系,出版了国内首部腹膜癌专著,制定2项腹膜癌诊治专家共识,在学科理论形成、研究平台建设、临床实践指南等方面,全面引领了国内腹膜肿瘤学学科发展。今年再度推出“腹膜转移癌研究”专栏,系统介绍我国腹膜癌领域的最新成果,促进临床肿瘤学的发展,推动腹膜肿瘤学学科建设。

关键词：腹膜转移临床肿瘤学专家共识

甲烷-丙烷二元混合气在流向变换催化燃烧器中反应特性的模拟研究

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动力工程学报 2015年第10期35卷 853-858,864页

作者：朱颖颖陈耿李信宝杨琦宁波大学海运学院浙江宁波315211

对甲烷和丙烷的二元混合气在流向变换催化燃烧器中的反应特性进行了模拟研究.选取总绝热温升作为基准参数,研究了混合气中甲烷所占比例和表观气速等运行条件对燃烧器运行规律和燃烧器熄火极限的影响.结果表明:甲烷和丙烷均在燃烧器入口... 详细信息

对甲烷和丙烷的二元混合气在流向变换催化燃烧器中的反应特性进行了模拟研究.选取总绝热温升作为基准参数,研究了混合气中甲烷所占比例和表观气速等运行条件对燃烧器运行规律和燃烧器熄火极限的影响.结果表明:甲烷和丙烷均在燃烧器入口附近迅速反应,且甲烷的总体反应速率低于丙烷;燃烧器内的温度水平随甲烷所占比例的增大而升高,流向变换催化燃烧器表现出床层最高温度随反应速率下降而上升的逆响应特性;甲烷和丙烷的催化燃烧过程均由本征反应动力学和传质过程共同控制;甲烷或丙烷单独反应时,燃烧器的熄火极限基本接近;甲烷-丙烷二元混合气的熄火浓度高于单一反应物,且当混合气中甲烷和丙烷的比例接近时,燃烧器的熄火极限最高.

关键词：流向变换催化燃烧器甲烷丙烷反应速率数值模拟