检索结果-南通市图书馆

A novel method for the spectrophotometric determination of cefradine by using sodium nitroprusside as chromogenic reagent

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2008年第12期19卷 1470-1474页

作者： Hua Zhang Ling Li Wu Quan Min Li xin zhen du College of Chemistry and Environmental Science Henan Normal University Xinxiang 453007 China College of Chemistry and Chemical Engineering Northwest Normal University Lanzhou 730070 China Henan Radio and Television University Zhengzhou 453008 China

A novel method is developed for the determination of cefradine by using sodium nitroprusside as chromogenic reagent. The experiment indicates that a russety product is formed by the reaction of cefradine with sodium nitroprusside in basic solution, and the maximum absorption wavelength （λmax） of russety product is 505 rim. And the sensitization of tetradecyl benzyl dimethyl ammonium chloride for the reaction of cefradine with sodium nitroprusside is remarkable, The apparent molar absorption coefficient （5505） is 2.81 × 103 L/mol cm. The linear equation isA = 0.0657 ＋ 0.00804C （μg/mL） in the range of 1.50-55.0μg/mL of cefradine with a correlation coefficient r = 0.9992, and the detection limit is 1.38 p,g/mL. This method has been applied to determine cefradine in capsule and tablet samples.

关键词： Cefradine Sodium nitroprusside Chromogenic reagent Spectrophotometry

Study on Room-Temperature Phosphorescence of 1-Bromonaphthalene in Media of Surfactant and β-Cyclodextrin

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1997年第5期8卷 431-434页

作者： xin zhen du Yun Bao JLANG Xian Zhi mANG and Guo zhen CHLN(The Research Laboratory of SEDC of Analytical Science for Matenal and Life ChemistryDepartmen: of Chermstn. Xiamer University. kiames 361005) XIAMEN UNIV DEPT CHEMRES LAB SEDC ANALYT SCI MAT & LIFE CHEMXIAMEN 361005PEOPLES R CHINA

Sdrictants(S) induced room-ternperature phorphorescence(RTP) frorn l-bromonaplithalene(l-BrN) in aerated aqueous solutions of o-cyclodextha(β-CD) hasbeco mvestigated m detail. lt has been fotmd that the partial incIu... 详细信息

关键词： Media Cyclodextrin Study on Room-Temperature Phosphorescence of 1-Bromonaphthalene in Media of Surfactant and

Chiral Separation of Erythromycin as a New Chiral Selector on CE

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2003年第3期14卷 280-282页

作者： Jing Guo HOU Tian Xi HE Xiao Qian HAN xin zhen du Xue Feng MAO Hua Ling DENG Jin Zhang GAO Department of Chemistry Northwest Normal UniversityLanzhou 730070

Erythromycin as a new chiral selector was first used for chrial separation of four derivatives of biphenyldimethylester enantiomers on CE. The influence of pH, the chiral selector concentration and organic modifiers ... 详细信息

关键词： Enantiomer erythromycin chiral selector CE.

STUDIES ON DERIVATIVE FLUORIMETRY Ⅳ. DETERMINATION OF TRACE AMOUNT OF TERBIUM THROUGH ITS TERNARY COMPLEX WITH ACETYLACETONE AND EDTA IN THE PRESENCE OF CETYL PYRIDINIUM CHLORIDE

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1992年第10期3卷 825-828页

作者： xin zhen du Jin Zhang GAO Jing Wan KANG Guang Bi BAI Institute of Chemistry Northwest Normal UniversityLanzhou730070

Terbium can form a ternary complex having a ratio of 1:1:1 with acetylacetone and EDTA. By adding cetyl pyridinium chloride into the above system, a marked enhancement of fluorescence intensity is observed and the ternary complex becomes more stable than before. For analytical application, the derivative spectrofluorimetric method has high sensitivity and the effect of foreign ions is very low. The optimum conditions were obtained. The calibration graph is linear over 5～100μg/mL.

关键词： EDTA CPC 络合试剂 STUDIES ON DERIVATIVE FLUORIMETRY DETERMINATION OF TRACE AMOUNT OF TERBIUM THROUGH ITS TERNARY COMPLEX WITH ACETYLACETONE AND EDTA IN THE PRESENCE OF CETYL PYRIDINIUM CHLORIDE ITS

同方期刊数据库

STUDIES ON FLUORESCENCE SPECTRA OF SAMARIUM EUROPIUM TERBIUM AND DYSPROSIUM WITH BENZOYL UREA DERIVATIVES AND PHENANTHROLINE

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 1993年第11期4卷 989-992页

作者： xin zhen du, Jin Zhang GAO, Qun XIE and Jing Wan KANG Institute of Chemistry, Northwest Normal University, Lanzhou 730070

Rare earth chelates of benzoyl urea derivatives were prepared in ethanol and fluorescence spectra of these chelates were studied in detail. A composition of [RE(BU)_3Phen] (NO_3)_3 was obtained. Correlation between chemical properties of ligands, chelates and spectroscopy was discussed. Intramolecular energy transfer in rare earth chelates was explained.

关键词： Eu STUDIES ON FLUORESCENCE SPECTRA OF SAMARIUM EUROPIUM TERBIUM AND DYSPROSIUM WITH BENZOYL UREA DERIVATIVES AND PHENANTHROLINE

我国高值药品保障原则探讨——基于国内外比较视角

在线全文

学校读者我要写书评

暂无评论

卫生经济研究 2017年第7期34卷 48-51页

作者：徐伟崔子丹江欣禅杜珍珍中国药科大学国际医药商学院江苏南京211198

通过综述我国青岛、香港,以及意大利、英国的高值药品保障原则,认为我国高值药品保障应遵循四点原则:重点保障重大疾病,适当拓宽疾病覆盖范围;明确药物适应症,适当纳入多种治疗药物;运用药物经济学方法辅助遴选;综合考虑医保基金的可持... 详细信息

通过综述我国青岛、香港,以及意大利、英国的高值药品保障原则,认为我国高值药品保障应遵循四点原则:重点保障重大疾病,适当拓宽疾病覆盖范围;明确药物适应症,适当纳入多种治疗药物;运用药物经济学方法辅助遴选;综合考虑医保基金的可持续发展。

关键词：重大疾病高值药品保障原则

高乌甲素、吗啡配伍罗哌卡因术后镇痛对肠功能恢复及血浆胃动素水平的影响

在线全文

学校读者我要写书评

暂无评论

陕西医学杂志 2007年第10期36卷 1386-1389页

作者：张昕王臻杜工亮王晖兰自侃陕西省人民医院西安710068

目的:比较高乌甲素与吗啡分别配伍罗哌卡因用于术后硬膜外镇痛对术后患者肠功能恢复及血浆胃动素水平的影响。方法:选择45例择期行胃癌根治术患者,随机分为3组:高乌甲素罗哌卡因组(L组,15例);吗啡罗哌卡因组(M组,15例);对照组(P组,15例)... 详细信息

目的:比较高乌甲素与吗啡分别配伍罗哌卡因用于术后硬膜外镇痛对术后患者肠功能恢复及血浆胃动素水平的影响。方法:选择45例择期行胃癌根治术患者,随机分为3组:高乌甲素罗哌卡因组(L组,15例);吗啡罗哌卡因组(M组,15例);对照组(P组,15例),哌替啶肌注组。测定术毕即刻、术毕6h、24h及48h血浆胃动素含量,同时记录术后48h内恶心呕吐程度、频率及肛门首次排气时间。结果:M组术毕24h胃动素水平明显高于其他两组(P0.05)。L组肛门排气时间明显短于P组和M组(P<0.05)。结论:高乌甲素配伍罗哌卡因用于术后镇痛,患者恶心、呕吐发生率低,且不影响胃肠道功能的恢复,值得推广。

关键词：镇痛,硬膜外手术后期间胃肠激素类胃肠活动 @高乌甲素

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige Jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing xin Yijing Zhao Yan Song Yahong Cheng Tong Li zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

As-cast microstructures and solidification paths of the Nb–Si–Ti ternary alloys in Nb_5Si_3–Ti_5Si_3region

在线全文

学校读者我要写书评

暂无评论

Rare Metals 2013年第5期32卷 502-511页

作者： Yan Li Chang-Rong Li zhen-Min du Cui-Ping Guo xin-Qing Zhao School of Materials Science and Engineering University of Science and Technology Beijing School of Materials Science and Engineering Beijing University of Aeronautics and Astronautics

Abstract The as-cast microstructures and solidification paths of the Nb-Si-Ti ternary alloys in the NbsSi3-TisSi3 region were investigated. Since there exist some isomor- phous compounds in the NbsSi3-TisSi3 region, such as aNbsSi3 with B3Cr5 prototype, 13NbsSi3 with Si3W5 pro- totype, 7NbsSi3 with MnsSi3 prototype, and TisSi3 with MnsSi3 prototype, the primary solidification areas of these compounds were not typically indentified in previous experiments. In the present paper, the microstructure observation, the phase identification, and the composition measurement were performed using scanning electron microscopy （SEM）, X-ray diffraction （XRD）, and electron probe microanalysis （EPMA）, respectively. No ternary compound is found. There exist three primary solidification areas, 13Nbs_x（Ti）xSi3, ~Nbs_x（Ti）xSi3, and Tis-x（Nb）xSi3 in the NbsSi3-TisSi3 region. Together with the literaturereported experimental data and optimization results, the liquidus projection of the whole Nb-Si-Ti ternary system is constructed, and totally ten primary solidification areas-- diamond-Si, Nb1-x（Ti）xSi2, Ti1-x（Nb）xSi2, Ti1-x（Nb）xSi, Ti5-x（Nb）xSi4, βNb5-x（Ti）xSi3,αNb5-x（Ti）xSi3, Ti5-x （Nb）xSi3, （Nb,Ti）3Si, and BCC--and nine transitional invariant reactions-L ＋ Nb1-x（Ti）xSi2 → Ti1-x（Nb）x Si2 ＋ Si, L ＋ Nb1-x（Ti）xSi2 → Ti1-x（Nb）xSi2 ＋ Ti5- （Nb）xSi4, L ＋ Ti5-x（Nb）xSi4 → Ti1-x（Nb）xSi2 ＋ Ti1-x （Nb）xSi, L ＋ 13Nb5-x（Ti）5Si3→ Nb1-x（Ti）xSi2 ＋ Ti5-x （Nb）xSi4, L ＋ βNb5-x（Ti）xSi3→b5-x（Ti）xSi3 ＋Ti5-x （Nb）xSi4, L ＋ αNb5-x（Ti）αSi3 → Ti5-x（Nb）xSi3 ＋ Ti5-x（Nb）x Si4, L ＋ αNb5-x（Ti）xSi3 →βNb5-x（Ti）xSi3 ＋ Ti5-x（Nb）xSi3, L ＋ βNb5-xTb-xSi3 → Ti5-x（Nb）xSi3 ＋（Nb,Ti）3Si, and L ＋（Nb,Ti）3Si → Ti5-x（Nb）xSi3 ＋ BCC are confirmed.

关键词： Nb-Si-Ti ternary system Liquidus projection Microstructure Solidification path