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light-Regulated Stomatal Aperture in Arabidopsis

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Molecular Plant 2012年第3期5卷 566-572页

作者： Chen Chen Yu-Guo Xiao xin li in ni Department of Plant Biology University of Minnesota Saint Paul MN 55108 USA

The stomatal pores of plant leaves, situated in the epidermis and surrounded by a pair of guard cells, allow CO2 uptake for photosynthesis and water loss through transpiration. Blue light is one of the dominant environmental signals that control stomatal movements in leaves of plants in a natural environment. This blue light response is mediated by blue/UV A light-absorbing phototropins （phots） and cryptochromes （crys）. Red/far-red light-absorbing phytochromes （phys） also play a role in the control of stomatal aperture. The signaling components that link the perception of light signals to the stomatal opening response are largely unknown. This review discusses a few newly discovered nuclear genes, their function with respect to the phot-, cry-, and phy-mediated signal transduction cascades, and possible involve- ment of circadian clock.

关键词： circadian clock cryptochromes phototropins phytochromes light signaling stomata

Rapid and easy determination of morphine in chafing dish condiments with colloidal gold labeling based lateral flow strips

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Food Science and Human Wellness 2019年第1期8卷 40-45页

作者： Wei Chen xin-ni li Qian Wu li Yao Jianguo Xu School of Food and Biological Engineering Engineering Research Center of Bio-processMOEHefei University of TechnologyHefei230009China

In order to enhance the flavor of chafing dish and increase the attraction of consumers,the poppy shell is reported to be illegally added to the condiments of chafing *** this research,a rapid,simple,and convenient method based on the classic immunochromatographic lateral flow strip(LFS)with gold nanoparticles(GNPs)labeling was developed for easy monitoring of morphine(MOP),an effective component of poppy *** optimized conditions,this developed LFS can well realize the detection of target MOP in the condiments of chafing dish in less than 10 min without any complicated *** limit of detection(LOD)can be achieved as low as 0.1 ppb for standard MOP or the MOP spiked condiments of chafing *** these results of the research strongly demonstrate that this established LFS method can be successfully applied in practical rapid and accurate on-site screening of poppy shell in condiments of chafing dish.

关键词： Morphine(MOP) Gold nanoparticles(GNPs) Lateral flow strip(LFS) Chafing dish condiments

Comparative genomics of Helicobacter pylori

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World Journal of Gastroenterology 2009年第32期15卷 3984-3991页

作者： Quan-Jiang Dong Qing Wang Ying-nin xin ni li Shi-Ying Xuan Department of Gastroenterology Qingdao Municipal Hospital Qingdao 266071 Shandong Province China

Genomic sequences have been determined for a number of strains of Helicobacter pylori （H pylori） and related bacteria. With the development of microarray analysis and the wide use of subtractive hybridization techniques, comparative studies have been carried out with respect to the interstrain differences between H pylori and inter-species differences in the genome of related bacteria. It was found that the core genome of H pylori constitutes 1111 genes that are determinants of the species properties. A great pool of auxiliary genes are mainly from the categories of cag pathogenicity islands, outer membrane proteins, restriction-modification system and hypothetical proteins of unknown function. Persistence of H pylori in the human stomach leads to the diversification of the genome. Comparative genomics suggest that a host jump has occurs from humans to felines. Candidate genes specific for the development of the gastric diseases were identified. With the aid of proteomics, population genetics and other molecular methods, future comparative genomic studies would dramatically promote our understanding of the evolution, pathogenesis and microbiology of Hpylori.

关键词： Helicobacterpylori Genomics Pathogenesis Cancer

Neuronal and synaptic adaptations underlying the benefits of deep brain stimulation for Parkinson’s disease

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Translational Neurodegeneration 2023年第1期12卷 90-110页

作者： Wenying Xu Jie Wang xin-ni li Jingxue liang Lu Song Yi Wu Zhenguo liu Bomin Sun Wei-Guang li Department of Rehabilitation Medicine Huashan HospitalInstitute for Translational Brain ResearchState Key Laboratory of Medical Neurobiology and Ministry of Education Frontiers Center for Brain ScienceFudan UniversityShanghai 200032China Department of Neurosurgery Center for Functional NeurosurgeryRuijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Department of Neurology Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China Ministry of Education-Shanghai Key Laboratory for Children’s Environmental Health Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai 200092China

Deep brain stimulation(DBS)is a well-established and effective treatment for patients with advanced Parkinson’s disease(PD),yet its underlying mechanisms remain ***,primarily conducted in animal models,provides a unique approach that allows cell type-and projection-specific modulation that mirrors the frequency-dependent stimulus effects of ***-DBS research in animal models plays a pivotal role in unraveling the neuronal and synaptic adaptations that contribute to the efficacy of DBS in PD ***-induced neuronal responses rely on a complex interplay between the distributions of presynaptic inputs,frequency-dependent synaptic depression,and the intrinsic excitability of postsynaptic *** orchestration leads to conversion of firing patterns,enabling both antidromic and orthodromic modulation of neural *** these mechanisms is vital for decoding position-and programming-dependent effects of ***,patterned stimulation is emerging as a promising strategy yielding long-lasting therapeutic *** on the neuronal and synaptic adaptations to DBS may pave the way for the development of more enduring and precise modulation *** technologies,such as adaptive DBS or directional electrodes,can also be integrated for circuit-specific *** insights hold the potential to greatly improve the effectiveness of DBS and advance PD treatment to new levels.

关键词： Parkinson’s disease Deep brain stimulation Optogenetics Opto-DBS Synaptic adaptation Orthodromic effects Antidromic effects Long-lasting therapeutic effects

AlGaN/GaN HEMTs on 4-Inch Silicon Substrates in the Presence of 2.7-μm -Thick Epilayers with the Maximum Off-State Breakdown Voltage of 500 V

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Chinese Physics Letters 2014年第3期31卷 129-132页

作者： YU xin-xin ni Jin-Yu li Zhong-Hui KONG Cen ZHOU Jian-Jun DONG Xun PAN Lei KONG Yue-Chan CHEN Tang-Sheng Science and Technology on Monolithic Integrated Circuits and Modules Laboratory Nanjing Electronic Devices Institute Nanjing 210016

We report on the high breakdown performance of AlGaN/GaN high electron mobility transistors （HEMTs） grown on 4-inch silicon substrates. The HEMT structure including three Al-content step-graded AlGaN transition layers has a total thickness of 2.7 μm. The HEMT with a gate width WG of 300 μm acquires a maximum off-state breakdown voltage （BV） of 550 V and a maximum drain current of 527 mA/mm at a gate voltage of 2 V. It is found that BV is improved with the increase of gate-drain distance LGD until it exceeds 8 μm and then BV is tended to saturation. While the maximum drain current drops continuously with the increase of LGD. The HEMT with a WG of 3 mm and a LGD of 8 μm obtains an off-state BV of 500 V. Its maximum leakage current is just 13 μA when the drain voltage is below 400 V. The device exhibits a maximum output current of 1 A with a maximum transconductance of 242 mS.

关键词： High electron mobility transistors

Synthesis of spherical nano-ZSM-5 zeolite with intergranular mesoporous for alkylation of ethylbenzene with ethanol to produce m-diethylbenzene

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Chinese Journal of Chemical Engineering 2024年第3期67卷 298-309页

作者： Siyue Wang Jinhong li Qingxin Xu Shengjie Song Yu'ni Jiang lidong Chen xin Shi Weiguo Cheng Faculty of Chemistry and Chemical Engineering Liaoning Normal UniversityDalian 110629China Beijing Key Laboratory of Ionic liquids Clean Process Key Laboratory of Green Process and EngineeringInstitute of Process EngineeringChinese Academy of SciencesBeijing 100190China

Catalytic synthesis of m-diethylbenzene(m-DEB)through alkylation of ethylbenzene(EB)may be a promising alternative route in comparison with traditional rectification of mixed DEB,for which the top priority is to develop efficient and stable heterogeneous ***,the spherical nano-ZSM-5 zeolite with abundant intergranular mesoporous is synthesized by the seed-mediated growth method for alkylation of EB with ethanol to produce *** results show that the spherical nano-ZSM-5 zeolite exhibits better stability and higher alkylation activity at a lower temperature than those of commercial micropore *** then,the spherical nano-ZSM-5 is further modified by La_(2)O_(3) through acid treatment followed by immersion *** acid treatment causes nano-ZSM-5 to exhibit the increased pore size but decreased the acid sites,and subsequent La_(2)O_(3) loading reintroduces the weak acid *** a result,the HNO_(3)-La_(2)O_(3)-modified catalyst exhibits a slight increase in EB conversion and DEB yield in comparison with unmodified one,and meanwhile,it still maintains high m-DEB *** catalyst after acid treatment achieves higher catalytic stability besides maintaining the high alkylation activity of EB with *** present study on the spherical nano-HZSM-5 zeolite and its modification catalyst with excellent alkylation ability provides new insights into the production of mDEB.

关键词： Zeolite Modification Alkylation reaction m-diethylbenzene Catalyst Fixed-bed

Carbon-coated hybrid crystals with fast electrochemical reaction kinetics for ultra-stable and high-load sodium-ion batteries

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Rare Metals 2024年第2期43卷 647-657页

作者： Chuan Ou Ming-Dong Tan Zhen-Bang li Zhao-Jie li Fei Tian Zheng-Ping Qiao Dan-ni Lei Cheng-xin Wang State Key Laboratory of Optoelectronic Materials and Technologies School of Materials Science and EngineeringSun Yat-Sen UniversityGuangzhou510275China

Owing to its high theoretical capacity and low cost,Sn has attracted significant attention in sodium-ion ***,the slow kinetics of electrochemical reactions and the rapid decay of capacity resulting from drastic changes in the volume of Sn,as well as persistent side reactions between Sn and the organic electrolyte during the(de)sodium process,have limited its *** improve the electrochemical performance of Sn-based materials,the bottom-up method is normally used to prepare carbon-coated ***,its complex preparation processes and harsh conditions make it unsuitable for practical ***,a carbon-coated hybrid crystal composite(Sn/SnO_(x)@C)was prepared using an up-bottom method with commercial Sn/SnO *** effects accelerate the electrochemical kinetics and inhibit the coarsening of Sn *** Sn/SnO_(x)@C composite electrode exhibited capacity retention of 80.7%even after approximately 1000 cycles(360.4 mAh·g^(−1)) at a current density of 1 A·g^(−1).The high-load Na_(3)V_(2)(PO4)3||Sn/SnO_(x)@C full cell presents a capacity retention rate of 91.7%after 150 cycles at the current density of 0.5 A·g^(−1).This work may significantly accelerate the commercialization of the Sn/SnO_(x)@C composite in sodium-ion batteries with high energy density.

关键词： Sodium-ion batteries(SIBs) Sn-based anode Ultraviolet curing Up-bottom method

Spectrum analysis of interval process model and its application in uncertain vibration analysis

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Science China(Technological Sciences) 2024年第8期67卷 2549-2564页

作者： li JinWu JIANG Chao ni BingYu State Key Laboratory of Advanced Design and Manufacturing Technology for Vehicle College of Mechanical and Vehicle EngineeringHunan UniversityChangsha 410082China

In recent years, the authors have extended the traditional interval method into the time dimension to develop a new mathematical tool called the “interval process model” for quantifying time-varying or dynamic uncertainties. This model employs upper and lower bounds instead of precise probability distributions to quantify uncertainty in a parameter at any given time point. It is anticipated to complement the conventional stochastic process model in the coming years owing to its relatively low dependence on experimental samples and ease of understanding for engineers. Building on our previous work, this paper proposes a spectrum analysis method to describe the frequency domain characteristics of an interval process, further strengthening the theoretical foundation of the interval process model and enhancing its applicability for complex engineering problems. In this approach, we first define the zero midpoint function interval process and its auto/cross-power spectral density(PSD) functions. We also deduce the relationship between the auto-PSD function and the auto-covariance function of the stationary zero midpoint function interval process. Next, the auto/cross-PSD function matrices of a general interval process are defined, followed by the introduction of the concepts of PSD function matrix and cross-PSD function matrix for interval process vectors. The spectrum analysis method is then applied to random vibration problems, leading to the creation of a spectrum-analysis-based interval vibration analysis method that determines the PSD function for the system displacement response under stationary interval process excitations. Finally, the effectiveness of the formulated spectrum-analysis-based interval vibration analysis approach is verified through two numerical examples.

关键词： interval process spectrum analysis power spectral density(PSD) time-varying uncertainty uncertain vibration analysis

Chemoselective electrochemical seleno-cyclization of dienes to medium-sized benzo[b]azocines

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Chinese Chemical Letters 2024年第2期35卷 431-435页

作者： Zhichuan Wang xin Wang Quanxin li Shaofei ni Dongyang Zhao Shubin Yang Ge Qiu Kai Sun College of Chemistry and Chemical Engineering Yantai UniversityYantai 264005China Department of Chemistry and Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province Shantou UniversityShantou 515063China Aix Marseille Univ. CNRSCentrale MarseilleiSm2MarseilleFrance

The preparation of medium-sized benzo[b]azocines has always been challenging because of inherently unfavorable enthalpy and entropy *** report presents a novel approach for accessing 8-membered seleno-benzo[b]azocines via electrochemically-driven *** method enables room-temperature preparation of various structurally diverse medium-sized seleno-benzo[b]*** facile deselenation of the seleno-cyclization products to generate functionalized dienes is an additional benefit of this indispensable *** insights are presented based on radical inhibition experiments and cyclic voltammetry measurements,which elucidate the radical ***,density functional theory calculations further rationalize the rate-determining step and the unique chemoselectivity observed in this transformation.

关键词： Medium-sized n-heterocycles Electrocatalysis Radical Mechanistic insights Selenylation