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Landau quantization and spin polarization of cold magnetized quark matter

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Chinese Physics C 2022年第6期46卷 164-173页

作者： Zhen-Yan Lu jian-Feng Xu xin-jian wen Guang-Xiong Peng Marco Ruggieri Hunan Provincial Key Laboratory of Intelligent Sensors and Advanced Sensor Materials School of Physics and ElectronicsHunan University of Science and TechnologyXiangtan 411201China School of Physics and Electrical Engineering Anyang Normal UniversityAnyang 455000China Departrnent of Physics and Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006China School ofNuclear Science and Technology University of Chinese Academy of SciencesBeijing 100049China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China School ofNuclear Science and Technology Lanzhou UniversityLanzhou 730000China

The magnetic field and density behaviors of various thermodynamic quantities of strange quark matter under compact star conditions are investigated in the framework of the thermodynamically self-consistent quasiparticle *** individual species,a larger number density n_(i) leads to a larger magnetic field strength threshold that aligns all particles parallel or antiparallel to the magnetic ***,in contrast to the finite baryon density effect which reduces the spin polarization of magnetized strange quark matter,the magnetic field effect leads to an enhancement of *** also compute the sound velocity as a function of the baryon density and find the sound velocity shows an obvious oscillation with increasing *** for the oscillation,the sound velocity grows with increasing density,similar to the zero-magnetic field case,and approaches the conformal limit V_(s)^(2)=1/3 at high densities from below.

关键词： Landau levels quark matter spin polarization strong magnetic field

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： xin Yang Yu-wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

阿司匹林与低抗凝剂量华法林治疗老年非瓣膜病房颤的临床疗效对比

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临床医学研究与实践 2016年第25期1卷 78-79页

作者：辛建文辛建勋陕西省宝鸡市眉县人民医院心血管内科陕西宝鸡722300

目的探讨阿司匹林与低抗凝剂量华法林对老年非瓣膜病房颤患者的出血、死亡、血栓栓塞发生的影响。方法将我院2013年2月至2016年2月收治的老年非瓣膜病房颤患者164例作为研究对象,随机分为A组和B组,各82例。其中A组患者给予阿司匹林进行... 详细信息

目的探讨阿司匹林与低抗凝剂量华法林对老年非瓣膜病房颤患者的出血、死亡、血栓栓塞发生的影响。方法将我院2013年2月至2016年2月收治的老年非瓣膜病房颤患者164例作为研究对象,随机分为A组和B组,各82例。其中A组患者给予阿司匹林进行治疗,B组患者给予调整剂量华法林抗凝治疗,观察两组患者的出血、死亡、血栓栓塞等事件的发生率。结果 A组患者血栓栓塞事件发生率明显高于B组,差异具有统计学意义(P0.05)。结论对于老年非瓣膜病房颤患者,应用低抗凝剂量华法林比阿司匹林临床效果好,可有效减少血栓栓塞事件的发生,安全可靠,建议临床推广使用。

关键词：阿司匹林华法林非瓣膜病房颤

Terfenol-D材料变负载时的磁致伸缩特性分析

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稀土 2004年第3期25卷 62-64页

作者：任翀汪建新文建平内蒙古科技大学内蒙古包头014010

关于稀土超磁致伸缩材料Terfenol-D的磁致伸缩特性国内外已有大量报道,但大多数都是基于载荷(预紧力)在磁致伸缩过程中保持不变条件下的磁致伸缩特性研究。本文在这些研究的基础上分析了Terfenol-D材料在变负载时的磁致伸缩特性,介绍了... 详细信息

关于稀土超磁致伸缩材料Terfenol-D的磁致伸缩特性国内外已有大量报道,但大多数都是基于载荷(预紧力)在磁致伸缩过程中保持不变条件下的磁致伸缩特性研究。本文在这些研究的基础上分析了Terfenol-D材料在变负载时的磁致伸缩特性,介绍了变负载动态特性曲线的求解方法并讨论了恒载与变载时特性曲线的特点与差异。

关键词：稀土磁致伸缩材料负载特性换能器

高光束质量、高功率稳定性激光器的设计及实验研究

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物理学报 2018年第7期67卷 134-142页

作者：郭晶郭福明陈基根杨玉军安然范小贞卢建新文侨深圳大学光电工程学院光电子器件与系统(教育部、广东省)重点实验室深圳518060

高光束质量、高功率稳定性激光器在激光加工、激光测量等领域具有广泛的用途.为了实现激光器腔内光斑聚焦同时减少色散和体积,人们常常将曲面反射镜用在激光谐振腔中,但光束倾斜入射到曲面反射镜往往会引起像散,从而导致光斑质量恶化,... 详细信息

高光束质量、高功率稳定性激光器在激光加工、激光测量等领域具有广泛的用途.为了实现激光器腔内光斑聚焦同时减少色散和体积,人们常常将曲面反射镜用在激光谐振腔中,但光束倾斜入射到曲面反射镜往往会引起像散,从而导致光斑质量恶化,并降低激光器的性能.另一方面,在高功率激光器或超短脉冲激光器中,激光增益介质热透镜焦距的起伏,是导致激光输出功率波动的主要原因之一.针对激光器的像散和功率波动这两个问题,本文提出了一套简单高效的解决方案,在考虑像散补偿和热透镜效应的基础上,基于传播变换圆理论,首次提出一种可实现高光束质量、高功率稳定性激光器谐振腔的设计方法,并对采用该方法所设计出的超短脉冲激光器进行理论与实验研究.研究结果表明,利用该方法设计的激光谐振腔,两端臂像散能够完全被补偿,实验上实现了基模高斯光束输出;当激光晶体热透镜焦距改变时,该方法所设计出的激光谐振腔内各关键位置光斑半径的变化,显著地小于普通谐振腔,在相同外界条件下,其输出激光功率稳定性明显优于普通激光器.

关键词：高光束质量高功率稳定性谐振腔设计

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang xin Liu jian Zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Metal-organic frameworks with dinuclear metal centers for synergistically boosting CO2 photoreduction

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Science China Chemistry 2025年第01期 201-208页

作者： Hui-Feng Wang wen-Jie Shi Yu-xin Yang Bao-Xia Dong Tong-Bu Lu Di-Chang Zhong School of Chemistry and Chemical Engineering Yangzhou University Institute for New Energy Materials and Low Carbon Technologies School of Materials Science and Engineering Tianjin University of Technology

Dinuclear metal synergistic catalysis （DMSC） has been proved powerful in boosting CO2reduction,while this has not been achieved in heterogeneous catalysts with long-range order *** this study,we,by introduction of metal catalytic centers into an indium-based metal-organic framework （MOF）,obtained a series of isostructural In-MOFs,including three MOFs with mononuclear metal catalytic center （M-In）,three MOFs with dinuclear homometallic catalytic centers （MM-In）,and three MOFs with dinuclear heterometallic catalytic centers (MM’-In,M/M’=Co（II）,Ni（II）,Zn（II）).It was found that all these MOFs can serve as catalysts for photochemical CO2reduction to *** with M-In,the catalytic activities of MM-In were obviously enhanced,and that of MM’-In was further significantly *** example,the CO yield of Co Zn-In reaches a record value of 12,700μmol g-1h-1,which is 4.0,8.1,9.4,and 18.6-fold higher than that of Co Co-In,Zn Zn-In,Co-In,and Zn-In,***,the catalytic activities of Co Ni-In and Ni Zn-In also show different fold increase than those of corresponding dinuclear homometallic and mononuclear metallic *** results of control experiments and theoretical calculation reveal that the higher catalytic activities of MM-In over M-In can be ascribed to the DMSC effect,and the higher catalytic activity of MM’-In over MM-In can be ascribed to the strengthened DMSC *** work reveals the relationship between DMSC effect and bimetal centers in CO2reduction,which provides new insights into the DMSC and paves a new way to design highly active catalysts for photochemical CO2reduction.

关键词：

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Mesospheric tide comparisons at low latitudes observed by two collocated meteor radars

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Earth and Planetary Physics 2025年第1期9卷 54-68页

作者： jian Li wen Yi XiangHui Xue Jie Zeng HaiLun Ye jianYuan Wang JinSong Chen Na Li TingDi Chen Chinese Academy of Sciences(CAS)Key Laboratory of Geospace Environment Department of Geophysics and Planetary SciencesUniversity of Science and Technology of ChinaHefei 230026China CAS Center for Excellence in Comparative Planetology Anhui Mengcheng Geophysics National Observation and Research StationUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230026China Collaborative Innovation Center of Astronautical Science and Technology Harbin 150001China National Key Laboratory of Electromagnetic Environment China Research Institute of Radiowave PropagationQingdao 266107China Yunnan Kunming Electromagnetic Environment National Observation and Research Station Qujing Kunming 655000China

Accurate knowledge of mesospheric winds and waves is essential for studying the dynamics and climate in the mesosphere and lower thermosphere(MLT)*** this study,we conduct a comparative analysis of the mesosphere tidal results obtained from two adjacent meteor radars at low latitudes in Kunming,China,from November 2013 to December *** two radars operate at different frequencies of 37.5 MHz and 53.1 MHz,***,overall good agreement is observed between the two radars in terms of horizontal winds and tide *** results show that the dominant tidal waves of the zonal and meridional winds are diurnal and semidiurnal ***,we conduct an exhaustive statistical analysis to compare the tidal amplitudes and vertical wavelengths recorded by the dual radar systems,which reveals a high degree of alignment in tidal *** investigation includes variances and covariances of tidal amplitudes,which demonstrate remarkable consistency across measurements from both *** finding highlights clear uniformity in the mesospheric tidal patterns observed at low latitudes by the two neighboring meteor *** of the comparative analysis specifically underscore the significant correlation in vertical wavelength measurements,validating the robustness of radar observations for tidal research.

关键词： mesosphere and lower thermosphere region meteor radar mesospheric winds tides

螺内酯、厄贝沙坦单用或联用对肥胖高血压患者血清脂联素及大动脉弹性的影响

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临床荟萃 2010年第8期25卷 647-650页

作者：田刚辛建文卢群西安交通大学医学院第一附属医院心内科陕西西安710061 眉县医院内科陕西眉县722300

目的观察螺内酯和厄贝沙坦单用或联用对肥胖高血压患者血清脂联素水平及大动脉弹性的影响。方法入选92例肥胖原发性高血压患者，随机分为螺内酯组（20mg／d，n=26），厄贝沙坦组（150mg／d，n=31）及联合组（螺内酯20mg／d＋厄贝沙坦15... 详细信息

目的观察螺内酯和厄贝沙坦单用或联用对肥胖高血压患者血清脂联素水平及大动脉弹性的影响。方法入选92例肥胖原发性高血压患者，随机分为螺内酯组（20mg／d，n=26），厄贝沙坦组（150mg／d，n=31）及联合组（螺内酯20mg／d＋厄贝沙坦150mg／d，n=35）治疗24周。测定各组治疗前后的体质量指数（BMI）、腰臀比值（WHR）、收缩压（SBP）、舒张压（DBP）和脉压（PP），采用放射免疫法检测血清脂联素水平，应用CVProfilor DO-2020型动脉功能检测仪检测大动脉弹性指数（C1）和小动脉弹性指数（C2）。结果与治疗前比较，药物治疗24周后，3组SBP、DBP、PP值均显著下降（P〈0．05或〈0．01），分别为螺内酯组SBP（144．0±9．4）mmHg vs（131．0±8．7）mmHg，DBP（88．4±10．4）mmHgvs（78．1±7．5）mmHg，PP（58．4±27．3）mmHgvs（54．3±9．2）mmHg；厄贝沙坦组SBP（146．0±9．4）mmHgvs（126．0±8．9）mmHg，DBP（85．4±10．1）mmHgvs（74．2±6．9）mmHg，PP（56．1±27．3）mmHgvs（49．9±8．8）mmHg；联合组SBP（145．0±9．3）mmHgvs（117．0±9．7）mmHg，DBP（87．8±10．7）mmHgvs（68．3±6．4）mmHg，PP（57．7±22．5）mmHgvs（45．4±8．7）mmHg。药物治疗24周后，SBP、DBP、PP值降低幅度联合组均分别大于螺内酯和厄贝沙坦单药治疗组（P〈0．01或〈0．05）。厄贝沙坦组血清脂联素水平的中位数和四分位间距[M（QR）]为[[5．6（2．31～8．21）]mg／Lvs12．8（2．48～20．12）]mg／L，动脉弹性功能指数C1[13．7（5．89～19．02）]ml／mmHg×10vs[10．3（4．52～17．02）]ml／mmHg×10，C2[5．1（1.38～7．98）]ml／mmHg×100vs[3．4（1．37～6．05）]ml／mmHg×100，均明显高于螺内酯组（均P〈0．05）；联合组血清脂联素水平[15．3（5．62～20．23）]mg／Lvs[5．4（2．13～8．16）]ml／L，动脉弹性功能指数C1[14．3（7．81～12．98）]ml／mmHg×10vs[10．2（5．02～19．10）]ml／mmHg×10，C2[5．9（1．62～8．20）]ml／mmHg×100vs[3．5（1．39～5．91）]ml／mmHg×100则分别显著高于螺内酯和厄贝沙坦组（P〈0．01或〈0．05）。结论螺内酯和厄贝沙坦联合应用提高肥胖高血压患者血清脂联素水平和改善动脉弹性的作用明显优于单药应用组。

关键词：高血压肥胖症螺内酯厄贝沙坦脂联素动脉弹性