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International Journal of Minerals,Metallurgy and Materials 2009年第1期16卷 119-123页

作者： Ting-feng Yi Yan-rong Zhu xin-guo hu School of Chemistry and Chemical Engineering Anhui University of Technology Maanshan 243002 China Department of Applied Chemistry Harbin Institute of Technology Harbin 150001 China

Powders of spinel LiLaxMn2-xO4 were successfully synthesized by the ultrasonic-assisted sol-gel （UASG） method. The structure and properties of LiLaxMn2-xO4 were examined by X-ray diffraction （XRD）, Fourier transform infrared （FT-IR） spectroscopy, scanning electronic microscopy （SEM）, galvanostatic charge-discharge test, and cyclic voltammetry （CV）. XRD results show that the La^3＋ can partially reptace Mn^3＋ in the spinel and the doped materials with La^3＋ have a larger lattice constant compared with pristine LiMn2O4. FT-IR indicates that the absorption peak of Mn^3＋-O and Mn^4＋- O bonds has a red and blue shift with the increase of doping lanthanum in LiLaxMn2-xO4, respectively. The charge-discharge test exhibits that the initial discharge capacity of LiLaxMn2-xO4 drops off, and the capacity retention increases gradually at C/5 discharge rate with the increase of doping lanthanum, and LiLa0.01Mn1.99O4 has a higher discharge capacity and a better cycling performance at 1C discharge rate. CV reveals that the doping La^3＋ is beneficial to the reversible extraction and intercalation of Li^＋ ions.

关键词： lithium ion battery cathode material lanthanum doping structure electrochemical performance

Effect of delayed sowing on grain number, grain weight, and protein concentration of wheat grains at specific positions within spikes

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Journal of Integrative Agriculture 2023年第8期22卷 2359-2369页

作者： Chu Jin-peng guo xin-hu ZHENG Fei-na ZHANG Xiu DAI xing-long HE Ming-rong State Key Laboratory of Crop Biology/Key Laboratory of Crop Ecophysiology and Farming System Ministry of Agriculture and Rural Affairs/Agronomy CollegeShandong Agricultural UniversityTai'an 271018P.R.China

Delays in sowing have significant effects on the grain yield,yield components,and grain protein concentrations of winter ***,little is known about how delayed sowing affects these characteristics at different positions in the wheat *** this study,the effects of sowing date were investigated in a winter wheat cultivar,Shannong 30,which was sown in 2019 and 2020 on October 8(normal sowing)and October 22(late sowing)under field *** sowing increased the partitioning of ^(13)C-assimilates to spikes,particularly to florets at the apical section of a spike and those occupying distal positions on the same ***,the increase in grain number was the greatest for the apical sections,followed by the basal and central *** significant differences were observed between sowing dates in the superior grain number in the basal and central sections,while the number in apical sections was significantly *** number of inferior grains in each section also increased substantially in response to delayed *** average grain weights in all sections remained unchanged under delayed sowing because there were parallel increases in grain number and ^(13)C-assimilate partitioning to grains at specific positions in the *** in grain number m^(–2) resulted in reduced grain protein concentrations as the limited nitrogen supply was diluted into more *** sowing caused the greatest reduction in grain protein concentration in the basal sections,followed by the central and apical *** significant differences in the reduction of the grain protein concentration were observed between the inferior and superior grains under delayed *** conclusion,a 2-week delay in sowing improved grain yield through increased grain number per spike,which originated principally from an increased grain number in the apical sections of spikes and in distal positions on the same ***,grain protein concentrations dec

关键词： wheat delay in sowing grain number grain weight grain protein concentration

Surgical treatment of a cervical spine fracture in an ankylosing spondylitis patient with severe global spine kyphosis and chin-on-chest deformity

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Chinese Medical Journal 2019年第21期132卷 2644-2646页

作者： xin-hu guo Hong-Quan Ji Department of Orthopedics Peking University Third HospitalBeijing 100191China.

To the Editor:Kyphotic deformity is one of the main manifestations of ankylosing spondylitis(AS).Usually,the hyperkyphosis is distributed along the lumbar,thoracolumbar,and thoracic spine,since the ossification of the spinal column mainly starts at the sacroiliac joint and then progresses towards the head.111 Occasionally,the kyphotic deformity occurs in the cervicothoracic spine,resulting in the chin resting on the chest,called chin-on-chest deformity?Patients with chin-on-chest deformity may have problems with horizontal gaze,chewing and swallowing,maintaining and performing proper personal hygiene,and they may suffer from neck pain and myelopathy.[1]However,severe global spine kyphosis in AS,resulting in a curvature of the upper body resembling the letter C,is an extremely rare condition with a simultaneous lumbar,thoracic,and cervicothoracic *** cervical spine fractures happen in these patients,it is very challenging to deal with them,because of the severity of the deformity and the instability of the *** this study,we report our experience in the treatment of a patient reporting these problems.

关键词： treatment spine curvature

Effects of genistein and equol on human and rat testicular 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase 3 activities

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Asian Journal of Andrology 2010年第4期12卷 519-526页

作者： guo-xin hu Bing-Hai Zhao Yan-hui Chu Hong-Yu Zhou Benson T. Akingbemi Zhi-Qiang Zheng Ren-Shan Ge Population Council New York NY 10065 USA School of Pharmacy Wenzhou Medical College Wenzhou 325000 China Heilongjiang Key Laboratory of Anti-fibrosis Biotherapy Mudanjiang Medical University Mudanjiang 157001 China Departments of Anatomy Physiology and Pharmacology Auburn University Auburn AL 36849 USA The Second Affiliated Hospital Wenzhou Medical College Wenzhou 325000 China

The objective of the present study was to investigate the effects of genistein and equol on 3β-hydroxysteroid de- hydrogenase （3β-HSD） and 17β-hydroxysteroid dehydrogenase 3 （17β-HSD3） in human and rat testis microsomes. These enzymes （3β-HSD and 17β-HSD3）, along with two others （cytochrome P450 side-chain cleavage enzyme and cytochrome P450 17α-hydroxylase/17-20 lyase）, catalyze the reactions that convert the steroid cholesterol into the sex hormone testosterone. Genistein inhibited 3β-HSD activity （0.2 μmol L^-1 pregnenolone） with half-maximal inhibition or a half-maximal inhibitory concentration （IC50） of 87 ± 15 （human） and 636 ± 155 nmol L^-1 （rat）. Genistein＇s mode of action on 3β-HSD activity was competitive for the substrate pregnenolonrge and noncompetitive for the cofactor NAD＋. There was no difference in genistein＇s potency of 3β-HSD inhibition between intact rat Leydig cells and testis microsomes. In contrast to its potent inhibition of 3β-HSD, genistein had lesser effects on human and rat 17β-HSD3 （0.1 μmol L^-1 androstenedione）, with an IC50 〉 100μmol L^-1. On the other hand, equol only inhibited human 3β-HSD by 42%, and had no effect on 3β-HSD and 17β-HSD3 in rat tissues. These observations imply that the ability of soy isoflavones to regulate androgen biosynthesis in Leydig cells is due in part to action on Leydig cell 3β- HSD activity. Given the increasing intake of soy-based food products and their potential effect on blood androgen levels, these findings are greatly relevant to public health.

关键词： 3β-hydroxysteroid dehydrogenase 17β-hydroxysteroid dehydrogenase 3 enzyme inhibition equol genistein

Study on Biocompatibility of Cross-linked Hyaluronic Acid Derivatives

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Chinese Journal of Biomedical Engineering(English Edition) 2009年第3期18卷 93-101页

作者： LIU xin hu guo-ying GU Han-qing Tianjin Institute of Urological Surgery Tianjin 300211 China

Objective:The cross-linked production,which was prepared by HA and cross-linking agent STMP,EDC,GP through cross-linking reaction,might be used in drug delivery system(DDS).To ensure the security of clinical application,the excellent properties such as none cell toxicity,nonirritant,none general toxicity,none immunological rejection are ***:In accordance with the request of GB/T 16886.1 on security evaluation of medical biomaterials,cell toxicity test,hemolysis test,intracutaneous stimulation test,acute toxicity test,and hypersensitive test were ***:Cell toxicity of HA-STMP,HA-EDC,HA-GP were all less than *** hypersensitive tests were *** HA-EDC,HA-GP produced different degrees of slight thrill,slight toxicity,hemolysis rate,which were larger than the standard ***:HA-STMP possesses favourable biocompatibility,which is a kind of ideal biomaterials and drug carriers.

关键词： hyaluronan (HA) cross-linked production biocompatibility

Study on Biological Properties of HA-TMP Cross-linked Products

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Chinese Journal of Biomedical Engineering(English Edition) 2010年第2期19卷 56-65页

作者： LIU xin hu guo-ying GU Han-qing Tianjin Institute of Urological Surgery Tianjin 300211 China

Objective:In the medium of ethanol(non-polar),STMP and ADH as crosslinkers to HA,to prepare drug delivery microspheres by getting stable cross-linked products without a gel phase,and to study biocompatibility and biodegradability of cross-linked ***:ISO10993.1-Safety Evaluation of Biomedical materials as a reference,to make hemolysis test,percutaneous stimulation test,acute toxicity test,and analyze in vitro degradation test,and degradation ***:HA-STMP cross-linked product had no hemolysis,no irritation,no acute systemic toxicity,but HA-ADH had a mild skin irritation and adverse acute systemic ***-STMP cross-linked product had lower sensitivity on HAse and the curve is *** the increase of degradation time HA-STMP results were changed by the structure analysis,degradation products of these cells were no ***:HA-STMP cross-linked products with better biocompatibility and better resistance to hydrolysis could delay the degradation time,which is suitable for the preparation of biodegradable drug carriers.

关键词： drug delivery biocompatibility biodegradability

Association factors of target organ damage： analysis of 17 682 elderly hypertensive patients in China

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Chinese Medical Journal 2011年第22期124卷 3676-3681页

作者： CUI hua WANG Fan FAN Li hu Yi-xin hu guo-liang LIU Lin HONG Chang-ming Chinese People＇s Liberation Army General Hospital （Fan L） Beijing 100853 China

Background Hypertensive target organ damage （TOD） is the main reason for mortality or disability in elderly hypertensive patients. The studies on TOD of hypertension in Asia, especially in Chinese elderly hypertensive patients, are very limited. The aim of this study was to evaluate the prevalence and correlative factors of TOD in older Chinese hypertensive inpatients. Methods This is a retrospective survey and data were collected from the computerized medical files of hypertensive inpatients from January of 1993 to December of 2008. The analysis was done on 17 682 inpatients, aged 60 years or older, with a diagnosis of essential hypertension （EH）. The evidence of hypertensive TOD and associated factors with TOD were collected. Results The prevalence of any hypertensive target organ involvement among these subjects was high. In multivariable Logistic regressions adjusted for potentially confounding factors, older age, male gender, diabetes, EH grade 3, systolic blood pressure （SBP）, and low-density lipoprotein cholesterol （LDL-C）, were independently associated with coronary artery disease. Age, duration of EH, EH grade 3, SBP, pulse pressure （PP）, and homocysteine （Hcy） were independently associated with cerebrovascular disease. Age, diabetes, duration of EH, EH grade 3, SBP, PP and estimated glomerular filtration rate （eGFR） were independently associated with chronic kidney disease. Male gender, EH grade 3 and SBP were independently associated with aortic dissection. Conclusions The prevalence of hypertensive TOD is high in older Chinese hypertensive inpatients. Various cardiovascular risk factors are associated with hypertensive TOD. The level of SBP and severe hypertension （grade 3 hypertension） are common independent risk factors of TOD.

关键词： hypertension target organ damage risk factors elderly inpatients

Effect of Nb-V microalloying on the hot deformation behavior of medium Mn steels

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International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 360-368页

作者： Yumeng Wang Qinyi guo Bin hu Haiwen Luo School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China

The influence of Nb-V microalloying on the hot deformation behavior and microstructures of medium Mn steel(MMS)was investigated by uniaxial hot compression *** establishing the constitutive equations for simulating the measured flow curves,we successfully constructed deformation activation energy(Q)maps and processing maps for identifying the region of flow *** concluded the following consequences of Nb-V alloying for MMS.(i)The critical strain increases and the increment diminishes with the increasing deformation temperature,suggesting that NbC precipitates more efficiently retard dynamic recrystallization(DRX)in MMS compared with solute Nb.(ii)The deformation activation energy of MMS is significantly increased and even higher than that of some reported high Mn steels,suggesting that its ability to retard DRX is greater than that of the high Mn content.(iii)The hot workability of MMS is improved by narrowing the hot processing window for the unstable flow stress,in which fine recrystallized and coarse unrecrystallized grains are present.

关键词： medium manganese steel niobium-vanadium microalloying flow behavior dynamic recrystallization hot workability

A Novel Semi-rigid Nephroscope Percutaneous Nephrolithotomy： The Best Therapy for Renal Staghorn Calculi

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Chinese Medical Journal 2015年第22期128卷 3109-3111页

作者： Bo Xiao Song Chen xin Zhang Wei-guo hu Yu-Bao Liu Yu-Zhe Tang Jian-xing Li Department of Urology Beijing Tsinghua Changgung Hospital Medical Center Tsinghua University Beijing 102218 China

Percutaneous nephrolithotomy （PCNL） has been the first-line treatment for renal staghorn calculi for many years. Several techniques have been described for percutaneous access and stone removal, but a multi-access approach is the mainstay of treatment. The main concern about PCNL is the resultant morbidity： Complications such as bleeding, parenchymal damage, and organ injury hindered the adoption of PCNL in primary hospitals in China.

关键词： Kidney Percutaneous Nephrolithotomy Semi-rigid Staghorn

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蕨类植物分类系统的一个新构想

安徽师范大学学报（自然科学版） 2010年第1期33卷 52-56页

作者：郭新弧安徽师范大学生命科学学院安徽芜湖241000

简要回顾了蕨类植物分类系统研究的历史,在秦仁昌教授1978年的分类系统的基础上,提出了一个新的蕨类植物分类系统的构想.即将蕨类植物门分为:松叶蕨亚门、石松亚门、楔叶亚门、真蕨亚门、水韭亚门、卷柏亚门、苹亚门等七个亚门,并对此... 详细信息

简要回顾了蕨类植物分类系统研究的历史,在秦仁昌教授1978年的分类系统的基础上,提出了一个新的蕨类植物分类系统的构想.即将蕨类植物门分为:松叶蕨亚门、石松亚门、楔叶亚门、真蕨亚门、水韭亚门、卷柏亚门、苹亚门等七个亚门,并对此进行了论述.

关键词：蕨类植物分类系统植物分类