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Competition of Composition Fluctuation Modes in Weakly Segregated Salt-doped Symmetric Diblock Copolymers

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Chinese Journal of Polymer Science 2024年第9期42卷 1375-1385,I0008页

作者： Yuan-xin zhou Xian Kong South China Advanced Institute for Soft Matter Science and Technology School of Emergent Soft MatterSouth China University of TechnologyGuangzhou510640China Guangdong Provincial Key Laboratory of Functional and Intelligent Hybrid Materials and Devices South China University of TechnologyGuangzhou510640China Yuan-Xin Zhou&Xian Kong

Salt-doped block copolymers have widespread applications in batteries,fuel cells,semiconductors,and various industries,where their properties crucially depend on phase separation ***,investigations into salt-doped diblock copolymers have predominantly focused on microphase separation,overlooking the segregation between ionic and polymeric *** study employs weak segregation theory to explore the interplay between phase separation dominated by the polymer-modulated mode and the salt-out-modulated mode,corresponding to microscopic and macroscopic phase separations,*** comparing diblock copolymers doped with salts to those doped with neutral solvents,we elucidate the significant role of charged species in modulating phase *** phase separation mode exhibits a transition between the polymer-modulated and salt-out-modulated modes at different *** systems doped with neutral solvents,this transition is stepwise,while in salt-ion-doped systems,it is *** a sufficiently large Flory-Huggins parameter between ions and polymers,the salt-out-modulated mode becomes dominant,promoting macrophase *** to the solvation effect of salt ions,salt-doped systems are more inclined to undergo microphase ***,we explore factors influencing the critical wavenumber of phase separation,including doping level and the Flory-Huggins parameters between two blocks and between ions and polymeric *** findings reveal that in a neutral solvent environment,these factors alter only the boundary between micro-and macro-phase separations,leaving the critical wavenumber unchanged in microphase separation ***,in a salt-doped environment,the critical wavenumber of microphase separation varies with these *** provides valuable insights into the pivotal role of electrostatics in the phase separation of salt-doped block copolymers.

关键词： Block copolymer Phase separation Field theory Salt-doped

Activation of leukotriene B_(4)receptor 1 is a prerequisite for complement receptor 3-mediated antifungal responses of neutrophils

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Cellular & Molecular Immunology 2024年第3期21卷 245-259页

作者： Yan xin Sihan Xiong Linghong zhou xin Lin Institute for Immunology and School of Medicine Tsinghua University100084BeijingChina Tsinghua University-Peking University Center for Life Sciences 100084BeijingChina Department of Infectious Diseases Shanghai Key Laboratory of Infectious Diseases and Biosafety Emergency ResponseNational Medical Center for Infectious DiseasesHuashan HospitalFudan UniversityShanghai200040China

Invasive fungal infections are life-threatening,and neutrophils are vital cells of the innate immune system that defend against *** role of LTA4H-LTB_(4)-BLT1 axis in regulation of neutrophil responses to fungal infection remains poorly ***,we demonstrated that the LTA4H-LTB_(4)-BLT1 axis protects the host against Candida albicans and Aspergillus fumigatus,but not Cryptococcus neoformans infection,by regulating the antifungal activity of *** results show that deleting Lta4h or Blt1 substantially impairs the fungal-specific phagocytic capacity of ***,defective activation of the spleen tyrosine kinase(Syk)and extracellular signal-related kinase(ERK1/2)pathways in neutrophils accompanies this ***,BLT1 regulates CR3-mediated,β-1,3-glucan-induced neutrophil phagocytosis,while a physical interaction with CR3 with slight influence on its dynamics is *** findings thus demonstrate that the LTA4H-LTB_(4)-BLT1 axis is essential for the phagocytic function of neutrophils in host antifungal immune response against Candida albicans and Aspergillus fumigatus.

关键词： LTA4H BLT1 Phagocytosis Complement receptor 3 Fungi

Hybrid model for BOF oxygen blowing time prediction based on oxygen balance mechanism and deep neural network

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International Journal of Minerals,Metallurgy and Materials 2024年第1期31卷 106-117页

作者： xin Shao Qing Liu Zicheng xin Jiangshan Zhang Tao zhou Shaoshuai Li State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China Engineering Research Center of MES Technology for Iron&Steel Production Ministry of EducationBeijing 100083China Laiwu Iron and Steel Group Yinshan Section Steel Co. Ltd.Jinan 271104China

The amount of oxygen blown into the converter is one of the key parameters for the control of the converter blowing process,which directly affects the tap-to-tap time of converter. In this study, a hybrid model based on oxygen balance mechanism (OBM) and deep neural network (DNN) was established for predicting oxygen blowing time in converter. A three-step method was utilized in the hybrid model. First, the oxygen consumption volume was predicted by the OBM model and DNN model, respectively. Second, a more accurate oxygen consumption volume was obtained by integrating the OBM model and DNN model. Finally, the converter oxygen blowing time was calculated according to the oxygen consumption volume and the oxygen supply intensity of each heat. The proposed hybrid model was verified using the actual data collected from an integrated steel plant in China, and compared with multiple linear regression model, OBM model, and neural network model including extreme learning machine, back propagation neural network, and DNN. The test results indicate that the hybrid model with a network structure of 3 hidden layer layers, 32-16-8 neurons per hidden layer, and 0.1 learning rate has the best prediction accuracy and stronger generalization ability compared with other models. The predicted hit ratio of oxygen consumption volume within the error±300 m^(3)is 96.67%;determination coefficient (R^(2)) and root mean square error (RMSE) are0.6984 and 150.03 m^(3), respectively. The oxygen blow time prediction hit ratio within the error±0.6 min is 89.50%;R2and RMSE are0.9486 and 0.3592 min, respectively. As a result, the proposed model can effectively predict the oxygen consumption volume and oxygen blowing time in the converter.

关键词： basic oxygen furnace oxygen consumption oxygen blowing time oxygen balance mechanism deep neural network hybrid model

A Proposed Systemic Modeling Software for Jujube Fruit Cracking

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American Journal of Plant Sciences 2015年第5期6卷 565-573页

作者： Yanbin Hua Yuqin Song Jie Li Caifang Tian xin-gen zhou Liulin Li College of Horticulture Shanxi Agricultural University Taigu Shanxi China College of Forestry Shanxi Agricultural University Taigu Shanxi China AgriLife Research and Extension Center Texas A&M University System Beaumont TX USA

Jujube fruit cracking has become a major concern in jujube production. It can affect fruit quality and yield and crop productivity, resulting in significant economic loss. Recent advances in jujube fruit cracking research provide opportunities to improve our understanding of the impacts of environmental factors and plant physiological metabolism on jujube fruit cracking. In this article, we have developed a novel systemic modeling software for jujube fruit cracking. The potential function and value of this modeling software are presented. Current issues and future research directions in the modeling of jujube fruit cracking system are also discussed. To our knowledge, this is the first functional and/or integrated modeling software developed for the management of jujube fruit cracking.

关键词： Modeling Software Jujube Fruit Cracking System Circadian Clock Metabolic Pathway Modeling

Epigenetic regulators as the foundation for molecular classification of colorectal cancer

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Cancer Biology & Medicine 2024年第7期21卷 547-552页

作者： Zhenyu Liu xin zhou Fuchou Tang School of Life Sciences Biomedical Pioneering Innovation CenterDepartment of General SurgeryThird HospitalPeking UniversityBejing 100871China Bejing Advanced Innovation Center for genomics(ICG) Ministry of Education Key Laboratory of Cell Proliferation and DifferentiationBeijing 100871China Peking University Third Hospital Cancer Center Bejing 100191China Academy for Advanced Interdisciplinary Studies Peking UniversityBeijing 100871China

Colorectal cancer (CRC) accounts for approximately 10% of newly diagnosed cancer cases and cancer-related deaths worldwide~1. The identification of molecular subtypes of CRCs has significantly advanced treatment strat... 详细信息

关键词： cancer colorectal cases

An Adaptive Program Recommendation System for Multi-User Sharing Environment

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China Communications 2024年第6期21卷 112-128页

作者： Sun Shiyun Hu Zhengying Wei xin zhou Liang School of Communications and Information Engineering Nanjing University of Posts and TelecommunicationsNanjing 210003China

More and more accounts or devices are shared by multiple users in video applications,which makes it difficult to provide recommendation *** recommendation schemes overlook multiuser sharing scenarios,and they cannot make effective use of the mixed information generated by multi-user when exploring users’potential *** solve these problems,this paper proposes an adaptive program recommendation system for multi-user sharing ***,we first design an offline periodic identification module by building multi-user features and periodically predicting target user in future sessions,which can separate the profile of target user from mixed log ***,an online recommendation module with adaptive timevarying exploration strategy is constructed by jointly using personal information and multi-user social information provided by identification *** one hand,to learn the dynamic changes in user-interest,a time-varying linear upper confidence bound(LinUCB)based on personal information is *** the other hand,to reduce the risk of exploration,a timeinvariant LinUCB based on separated multi-user social information from one account/device is proposed to compute the quality scores of programs for each user,which is integrated into the time-varying LinUCB by cross-weighting ***,experimental results validate the efficiency of the proposed scheme.

关键词： adaptive exploitation LinUCB multiuser recommendation system

SmartEagleEye:A Cloud-Oriented Webshell Detection System Based on Dynamic Gray-Box and Deep Learning

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Tsinghua Science and Technology 2024年第3期29卷 766-783页

作者： xin Liu Yingli Zhang Qingchen Yu Jiajun Min Jun Shen Rui zhou Qingguo zhou School of Information Science and Engineering Lanzhou UniversityLanzhou 730000China College of Computer Science and Technology Zhejiang UniversityHangzhou 310058China School of Computing and Information Technology University of WollongongWollongong 2500Australia

Compared with traditional environments,the cloud environment exposes online services to additional vulnerabilities and threats of cyber attacks,and the cyber security of cloud platforms is becoming increasingly prominent.A piece of code,known as a Webshell,is usually uploaded to the target servers to achieve multiple *** Webshell attacks has become a hot spot in current ***,the traditional Webshell detectors are not built for the cloud,making it highly difficult to play a defensive role in the cloud ***,a Webshell detection system based on deep learning that is successfully applied in various scenarios,is proposed in this *** system contains two important components:gray-box and neural network *** gray-box analyzer defines a series of rules and algorithms for extracting static and dynamic behaviors from the code to make the decision *** neural network analyzer transforms suspicious code into Operation Code(OPCODE)sequences,turning the detection task into a classification *** experiment results show that SmartEagleEye achieves an encouraging high detection rate and an acceptable false-positive rate,which indicate its capability to provide good protection for the cloud environment.

关键词： Webshell detection cloud web security deep learning

A reweighted damped singular spectrum analysis method for robust seismic noise suppression

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Petroleum Science 2024年第3期21卷 1671-1682页

作者： Wei-Lin Huang Yan-xin zhou Yang zhou Wei-Jie Liu Ji-Dong Li State Key Laboratory of Petroleum Resources and Engineering China University of Petroleum(Beijing)Beijing2249China SINOPEC Petroleum Exploration and Production Research Institute Beijing102206China SINOPEC Geophysical Research Institute Nanjing211103jiangsuChina

(Multichannel)Singular spectrum analysis is considered as one of the most effective methods for seismic incoherent noise *** utilizes the low-rank feature of seismic signal and regards the noise suppression as a low-rank reconstruction ***,in some cases the seismic geophones receive some erratic disturbances and the amplitudes are dramatically larger than other *** presence of this kind of noise,called erratic noise,makes singular spectrum analysis(SSA)reconstruction unstable and has undesirable effects on the final *** robustify the low-rank reconstruction of seismic data by a reweighted damped SSA(RD-SSA)*** incorporates the damped SSA,an improved version of SSA,into a reweighted *** damping operator is used to weaken the artificial disturbance introduced by the low-rank projection of both erratic and random *** central idea of the RD-SSA method is to iteratively approximate the observed data with the quadratic norm for the first iteration and the Tukeys bisquare norm for the rest *** RD-SSA method can suppress seismic incoherent noise and keep the reconstruction process robust to the erratic *** feasibility of RD-SSA is validated via both synthetic and field data examples.

关键词： Singular spectrum analysis Damping operator Seismic erratic noise Seismic signal processing Robust low-rank reconstruction

Synthesis of photostable near-infrared sulfone-rhodamines for photoacoustic imaging-guided photothermal therapy

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Chinese Chemical Letters 2024年第3期35卷 369-372页

作者： Huiyu Si Dongjuan Wang Xianfa Du xin zhou Department of Chemistry College of Chemistry and Chemical EngineeringQingdao UniversityQingdao 266071China Department of Orthopedics the Affiliated Hospital of Qingdao UniversityQingdao 266071China

Photothermal therapy(PTT)is a cutting-edge cancer treatment that can kill cancer cells in hypoxic environments without relying on *** of the ideal photothermal agents with a high absorption coefficient in the near-infrared region,and a high excellent photothermal conversion efficiency is of great ***-Rhodanmine dye has showed an impressive absorption wavelength over 700 nm,but suffered from a stability *** this study,we synthesized five sulfone rhodamines and investigated the substitution effects on ***_(2)R2 showed high stability and strong absorbance at 714 nm with an excellent photothermal conversion efficiency of 53.06%,making it suitable for accurate photoacoustic imaging-guided photothermal therapy in vivo.

关键词： Photothermal therapy Sulfone rhodamine Near-Infrared Photoacoustic Imaging