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Measurements of the ^(107)Ag neutron capture cross sections with pulse height weighting technique at the CSNS Back-n facility

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Chinese Physics B 2022年第3期31卷 109-116页

作者： xin-xiang li Long-xiang liu Wei Jiang Jie Ren Hong-Wei Wang Gong-Tao Fan Jian-Jun He Xi-Guang Cao Long-Long Song Yue Zhang xin-Rong Hu Zi-Rui Hao Pan Kuang Bing Jiang Xiao-He Wang Ji-Feng Hu Jin-Cheng Wang De-xin Wang Su-Yalatu Zhang Ying-Du liu Xu Ma Chun-Wang Ma Yu-Ting Wang Zhen-Dong An Jun Su li-Yong Zhang Yu-Xuan Yang Wen-Bo liu Wan-Qing Su Sheng Jin Kai-Jie Chen Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China University of Chinese Academy of Sciences Beiing 100049China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201210China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China China Spallation Neutron Source Dongguan 523803China China Institute of Atomic Energy Beijing 102413China Key Laboratory of Beam Technology and Material Modification of Ministry of Education College of Nuclear Science and TechnologyBeijing Normal UniversityBeijing 100875China Beijing Radiation Center Bejing 100875China College of Mathematics and Physics Inner Mongolia Minzu UniversityTongliao 0280000 China xiangtan University Xiangtan 411105China Henan Normal University Xinxiang 453007China Sun Yat-sen University Zhuhai 510275China ShanghaiTech University Shanghai 200120China

Silver indium cadmium(Ag–In–Cd) control rod is widely used in pressurized water reactor nuclear power plants,and it is continuously consumed in a high neutron flux environment. The mass ratio of ^(107)Ag in the Ag–In–Cd control rod is 41.44%. To accurately calculate the consumption value of the control rod, a reliable neutron reaction cross section of the ^(107)Ag is required. Meanwhile,^(107)Ag is also an important weak r nucleus. Thus, the cross sections for neutron induced interactions with ^(107)Ag are very important both in nuclear energy and nuclear astrophysics. The(n, γ) cross section of ^(107)Ag has been measured in the energy range of 1–60 eV using a back streaming white neutron beam line at China spallation neutron source. The resonance parameters are extracted by an R-matrix code. All the cross section of ^(107)Ag and resonance parameters are given in this paper as datasets. The datasets are openly available at http://***/10.11922/sciencedb.j00113.00010.

关键词： neutron capture cross section pulse height weighting technique(PHWT) ^(107)Ag(n γ)^(108)Ag the China spallation neutron source(CSNS)Back-n facility

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Measurement of Br(n,γ)cross sections up to stellar s-process temperatures at the CSNS Back‑n

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Nuclear Science and Techniques 2023年第11期34卷 226-241页

作者： Gao‑Le Yang Zhen‑Dong An Wei Jiang Xian‑Kai li Wei‑Wei Qiu Zheng‑Fa liao Zi‑Yue Zhuang Xiao‑Ping Zhang Sheng‑li Chen Chen‑Chen Guo Er‑Xi Xiao Xiao Fang xin‑xiang li xin‑Rong Hu Bing Jiang Jin‑Cheng Wang Jie Ren Wen Luo Zhi‑Chao Zhu Hao‑Yang Lan Zong‑Wei Cao Xu Ma Ying‑Du liu Pu‑Sen Wang Yi Yang Ping Su Xian‑Gai Deng Wan‑Bing He Chun‑Wang Ma Yu‑Ting Wang Zhi‑Tao Dai Peng‑Qin He Ren‑Guang Tang Tao Zhou Jing Wang Han Yi Yue Zhang Yong‑Hao Chen Rui‑Rui Fan Ke‑Qing Gao Qiang li Kang Sun Zhi‑xin Tan Min‑Hao Gu Han‑Tao Jing Jing‑Yu Tang School of Physics and Astronomy Sun Yat-sen UniversityZhuhai 519082China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China State Key Laboratory of Lunar and Planetary Sciences Macao University of Science and TechnologyMacao 999078China CNSA Macao Center for Space Exploration and Science Macao 999078China Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of South ChinaHengyang 421001China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China School of Materials Science and Engineering Xiangtan UniversityXiangtan 411100China Key Laboratory of Nuclear Physics and Ion‑beam Application(MOE) Institute of Modern PhysicsDepartment of Nuclear Science and TechnologyFudan UniversityShanghai 200433China Institute of Particle and Nuclear Physics Henan Normal UniversityXinxiang 453007China School of Physics Henan Normal UniversityXinxiang 453007China Shenzhen Center Cancer hospitalChinese Academy of Medical SciencesShenzhen 518100China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China

The neutron capture cross sections(n,γ)of bromine were obtained using the time-of-flight technique at the Back-n facility of the China Spallation Neutron ***γ-rays originating from neutron-induced capture events were detected using four C_(6)D_(6) *** pulse-height weighting technique and double-bunch unfolding method based on Bayesian theory were used in the data *** deductions,normalization,and corrections were carefully considered to obtain reliable measurement *** multilevel R-matrix Bayesian code SAMMY was used to extract the resonance parameters in the resolved resonance region(RRR).The average cross sections in the unresolved resonance region(URR)were obtained from 10 to 400 *** experimental results were compared with data from several evaluated libraries and previous experi-ments in the RRR and *** TALYS code was used to describe the average cross sections in the *** astrophysical Maxwell average cross sections(MACSs)of ^(79,81)Br from kT=5 to 100 keV were calculated over a sufficiently wide range of neutron *** a thermal energy of kT=30 keV,the MACS value for ^(79)Br 682±68 mb was in good agreement with the KADoNiS v1.0 recommended *** contrast,the value of 293±29 mb for ^(81)Br was substantially higher than that of the evaluated database and the KADoNiS v1.0 recommended value.

关键词： Time-of-flight technique Neutron capture cross sections Maxwell average cross sections

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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan Zhao Yidan Zhang xin liu Jian Zhang Ya Gao Shuyue li Cui Chang xiang liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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Effect of notoginsenoside R1 on hepatic microcirculation disturbance induced by gut ischemia and reperfusion

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World Journal of Gastroenterology 2008年第1期14卷 29-37页

作者： Wei-xing Chen Fang Wang, Yu-Ying liu, Qing-Jiang Zeng, Kai Sun, xin Xue, xiang li, Ji-Ying Yang, li-Hua An,Bai-He Hu, Jin-Hui Yang, Chuan-She Wang, Zhi-xin li, lian-Yi liu, Yan li, Jun Zheng, Fu-Long liao, Dong Han,Jing-Yu Fan, Jing-Yan Han Fang Wang Yu-Ying liu Qing-Jiang Zeng Kai Sun xin Xue xiang li Ji-Ying Yang li-Hua An Bai-He Hu Jin-Hui Yang Chuan-She Wang Zhi-xin li lian-Yi liu Yan li Jun Zheng Fu-Long liao Dong Han Jing-Yu Fan Jing-Yan Han Tasly Microcirculation Research Center Peking University Health Science Center Beijing 100083 China Department of Pharmacology Tianjin University of Traditional Chinese Medicine Tianjin 300193 China Department of Integrated Chinese and Western Medicine School of Basic Medical Sciences Peking University Beijing 100083 China

AIM： To assess the effect of notoginsenoside R1 on hepatic microcirculatory disturbance induced by gut ischemia/reperfusion （I/R） in mice. METHODS： The superior mesenteric artery （SMA） of C57/BL mice was ligated for 15 min to induce gut ischemia followed by 30-rain reperfusion. In another set of experiments, R1 was continuously infused （10 mg/kg per hour） from 10 min before I/R until the end of the investigation to study the influence of R1 on hepatic microcirculatory disturbance induced by gut I/R. Hepatic microcirculation was observed by inverted microscopy, and the vascular diameter, red blood cell （RBC） velocity and sinusoid perfusion were estimated. Leukocyte rolling and adhesion were observed under a laser confocal microscope. Thirty and 60 min after reperfusion, lactate dehydrogenase （LDH）, alanine aminotransferase （ALl＇） and aspartate transaminase （AST） in peripheral blood were determined. The expression of adhesion molecules CD11b/CD18 in neutrophils and tumor necrosis factor- alpha （TNF-α）, interleukin-6 （IL-6） and monocyte chemotactic protein-1 （MCP-1） in plasma were evaluated by flow Oltometry. E-selectin and intercellular adhesion molecule-1 （ICAM-1） in hepatic tissue were examined by ***： After gut I/R, the diameters of terminal portal venules and central veins, RBC velocity and the number of perfused sinusoids were decreased, while the leukocyte rolling and adhesion, the expression of E-selectin in hepatic vessels and CD18 in neutrophils, IL-6, MCP-1, LDH, ALT and AST were increased. R1 treatment attenuated these alterations except for IL-6 and MCP-1. CONCLUSION： R1 prevents I/R-induced hepatic microcirculation disturbance and hepatocyte injury, The effect of R1 is related to its inhibition of leukocyte rolling and adhesion by inhibiting the expression of E-selectin in endothelium and CD18 in neutrophils.

关键词： Ischemia/reperfusion Notoginsenoside R1 Leukoytes adhesion E-selectin Hepatic injury

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基于按需和贪婪转发的移动自组网路由协议

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工程科学学报 2017年第5期39卷 778-785页

作者：黄金科樊晓光向新李帅空军工程大学航空航天工程学院西安710038

移动自组网的动态拓扑特性给路由协议的设计带来了一定的挑战,尤其是在高动态的网络环境中.本文针对该问题,提出了一种新的基于按需和贪婪转发的路由协议,该协议是在RGR模式的基础上提出以下三点改进,即:(1)通过受限的洪泛机制降低网络... 详细信息

移动自组网的动态拓扑特性给路由协议的设计带来了一定的挑战,尤其是在高动态的网络环境中.本文针对该问题,提出了一种新的基于按需和贪婪转发的路由协议,该协议是在RGR模式的基础上提出以下三点改进,即:(1)通过受限的洪泛机制降低网络在路由发现阶段的控制开销;(2)通过移动预测机制,在被动寻路阶段监视被动路径的状态和在GGF阶段帮助节点选取适当的邻居作为下一跳节点;(3)通过路径请求延迟机制以减少不必要的资源浪费.仿真结果表明:改进的RGR协议与现有的RGR、AODV、Modified-RGR和Optimized-RGR相比,不仅具有较高的数据包接收成功率,而且平均路由开销和端到端时延也相对较低.

关键词：移动自组织网路由协议受限洪泛移动预测路由请求延迟性能分析

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Kangfuxin solution alleviates esophageal stenosis after endoscopic submucosal dissection:A natural ingredient strategy

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World Journal of Gastroenterology 2025年第1期31卷 110-125页

作者： xin Zhou Dan Ma Yi-xiang He Jing Jin Hong-lian Wang Yun-Feng Wang Fan Yang Jian-Qin liu Jie Chen Zhi li Department of Spleen and Stomach Diseases the Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina The Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Digestive System Diseases of Luzhou City The Affiliated Traditional Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina Department of Gastroenterology Changhai HospitalNaval Medical UniversityShanghai 20082China Research Center of Integrated Chinese and Western Medicine The Affiliated Traditional Chinese Medicine HospitalSouthwest Medical UniversityLuzhou 646000Sichuan ProvinceChina School of Integrated Traditional Chinese and Western Clinical Medicine North Sichuan Medical CollegeNanchong637100Sichuan ProvinceChina

BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after *** To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus *** Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential *** examinations occurred on days 7 and 21 *** vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was *** signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after *** treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal ***,the expression of fibrotic effector molecules was notably ***,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/*** vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen *** 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated *** KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.

关键词： Kangfuxin solution Natural component Endoscopic submucosal dissection Esophagus stricture Fibrosis

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Multi-Stage-Based Siamese Neural Network for Seal Image Recognition

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 405-423页

作者： Jianfeng Lu xiangye Huang Caijin li Renlin xin Shanqing Zhang Mahmoud Emam School of Computer Science and Technology Hangzhou Dianzi UniversityHangzhou310018China Shangyu Institute of Science and Engineering Hangzhou Dianzi UniversityShaoxing312300China Faculty of Artificial Intelligence Menoufia UniversityShebin El-Koom32511Egypt

Seal authentication is an important task for verifying the authenticity of stamped seals used in various domains to protect legal documents from tampering and *** seal inspection is commonly audited manually to ensure document ***,manual assessment of seal images is tedious and laborintensive due to human errors,inconsistent placement,and completeness of the *** image recognition systems are inadequate enough to identify seal types accurately,necessitating a neural network-based method for seal image ***,neural network-based classification algorithms,such as Residual Networks(ResNet)andVisualGeometryGroup with 16 layers(VGG16)yield suboptimal recognition rates on stamp ***,the fixed training data categories make handling new categories to be a challenging *** paper proposes amulti-stage seal recognition algorithmbased on Siamese network to overcome these ***,the seal image is pre-processed by applying an image rotation correction module based on Histogram of Oriented Gradients(HOG).Secondly,the similarity between input seal image pairs is measured by utilizing a similarity comparison module based on the Siamese ***,we compare the results with the pre-stored standard seal template images in the database to obtain the seal *** evaluate the performance of the proposed method,we further create a new seal image dataset that contains two subsets with 210,000 valid labeled pairs in *** proposed work has a practical significance in industries where automatic seal authentication is essential as in legal,financial,and governmental sectors,where automatic seal recognition can enhance document security and streamline validation ***,the experimental results show that the proposed multi-stage method for seal image recognition outperforms state-of-the-art methods on the two established datasets.

关键词： Seal recognition seal authentication document tampering siamese network spatial transformer network similarity comparison network

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Current status of drug therapy for chronic hepatitis B

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World Journal of Gastroenterology 2025年第2期31卷 1-12页

作者： Chuang Jiang Zhi-Hong Zhang Jia-xin li Division of liver Surgery Department of General Surgery and Laboratory of Liver Surgeryand State Key Laboratory of Biotherapy and Collaborative Innovation Center of BiotherapyWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of General Surgery Dafang County People's HospitalBijie 551600Guizhou ProvinceChina

In this editorial,we comment on the article by Meng et *** hepatitis B(CHB)is a significant global health problem,particularly in developing *** B virus(HBV)infection is one of the most important risk factors for cirrhosis and hepatocellular *** and treatment of HBV are key measures to reduce *** present,drug therapy can effectively control virus replication and slow disease progression,but completely eliminating the virus remains a ***-HBV treatment is a long-term process,and there are many kinds of antiviral drugs with different mechanisms of action,it is essential to evaluate the safety and efficacy of these drugs to reduce side effects and improve patients’*** will summarize the current status of CHB drug treatment,hoping to provide a reference for the selection of clinical antiviral drugs.

关键词： Chronic hepatitis B Hepatitis B virus Anti virus Drug treatment Therapy

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O2O商业模式中闭环的形成机制研究——基于信任迁移的视角

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经济管理 2017年第10期43卷 62-81页

作者：张新香胡立君中南财经政法大学信息与安全工程学院湖北武汉430073 中南财经政法大学现代产业经济研究中心湖北武汉430073

闭环构建是O2O商业模式成功的关键论题,信任在闭环构建中承担重要角色。O2O模式中,消费者信任分布在线上平台和线下商家,线上线下信任交互影响,串行传递。本文注意到O2O模式中的信任迁移与闭环构建之间的内在联系,设计研究模型,以农村旅... 详细信息

闭环构建是O2O商业模式成功的关键论题,信任在闭环构建中承担重要角色。O2O模式中,消费者信任分布在线上平台和线下商家,线上线下信任交互影响,串行传递。本文注意到O2O模式中的信任迁移与闭环构建之间的内在联系,设计研究模型,以农村旅游O2O为研究对象,采用问卷调查收集256份消费者样本,实证检验结果表明,特别保证感知、平台质量感知正向影响线上初始信任。在线评价有效性和在线信息有效性作为中介变量,驱动线上初始信任向线下初始信任迁移,线下初始信任激发线下体验动机。线下体验后,质量形象、服务形象等形象变量帮助建立线下持续信任,线下持续信任形成中的体验感知和对O2O平台的初始感知共同影响消费者对线上平台的持续信任,线上持续信任赢取消费者的态度忠诚和行为忠诚。"线上—线下—线上"的信任迁移路径很好地诠释了O2O闭环的形成机理,信任迁移的实现策略同时回答了O2O闭环的构建机制。基于研究结论,本文为O2O环路的构建和稳固提出了有效可行的管理建议。

关键词： O2O模式闭环线上信任线下信任信任迁移

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野生余甘子中超氧化物歧化酶SOD的提取工艺研究

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食品科技 2010年第12期35卷 198-200,205页

作者：宋欣李翔成都中医药大学药学院成都611137

通过考察抽提野生余甘子的缓冲液pH、抽提体积和抽提温度进行优化,探讨余甘子SOD的最佳提取工艺.结果表明:抽提缓冲液的pH7.8,抽提体积为2倍,抽提温度为4℃时,得到余甘子SOD的提取的粗酶活性为198.47 U/mL(。NH4)2SO4饱和度为80%时,余甘... 详细信息

通过考察抽提野生余甘子的缓冲液pH、抽提体积和抽提温度进行优化,探讨余甘子SOD的最佳提取工艺.结果表明:抽提缓冲液的pH7.8,抽提体积为2倍,抽提温度为4℃时,得到余甘子SOD的提取的粗酶活性为198.47 U/mL(。NH4)2SO4饱和度为80%时,余甘子SOD能够达到相对最大酶活性。

关键词：野生余甘子超氧化物歧化酶提取

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