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Full Power Hydraulic Brake System Based on Double Pipelines for Heavy Vehicles

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Chinese Journal of Mechanical Engineering 2011年第5期24卷 790-797页

作者： gong Mingde wei Hailong College of Mechanical Science and Engineering Jilin University Changchun 130025 China

The hydraulic caliper disc brake system with air-over-oil is widely adopted at present for heavy vehicles,which makes use of air pressure system propelling the hydraulic pressure system acting on friction plates divided and combined for *** are some disadvantages such as pneumatic components failure,dust polluted and produce lots of heat in hydraulic caliper disc brake ***,considering the demands of the high speed,heavy weight,heavy load and fast brake of heavy vehicles,the full power hydraulic brake system based on double pipelines for heavy vehicles is designed and analyzed in this *** scheme of the full power hydraulic brake system,in which the triloculare cylinder is controlled by dual brake valve,is adopted in the brake *** full power hydraulic brake system can accomplish steering brake,parking brake and emergent brake for heavy ***,electronic control system that is responsible for coordinating the work of hydraulic decelerator and hydraulic brake system is developed for different speed *** on the analysis of the influence of composed unit and connecting pipeline on braking performance,the nonlinear mathematic model is established for the full power hydraulic brake *** braking completion time and braking pressure in braking performance of the double-pipeline steering brake and parking brake are discussed by means of simulation experiments based on Matlab/Simulink,and the simulation results prove that the braking performance of steering brake and parking brake meets the designing requirement of the full power hydraulic brake ***,the test-bed experiments of the brake system for heavy vehicles are carried *** experimental data prove that the braking performance achieves the goal of the design,and that the full power hydraulic brake system based on double pipelines can effectively enhance braking performance,ensure braking reliability and security for heavy vehicles.

关键词： heavy vehicle full power hydraulic brake system double-pipeline brake triloculare cylinder braking performance

Solid-state batteries: from fundamental interface characterization to realize sustainable promise

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Rare Metals 2020年第7期39卷 743-744页

作者： Yu-xin gong Jia-Jun Wang MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage School of Chemistry and Chemical EngineeringHarbin Institute of TechnologyHarbin 150001China

The highly conductive solid-state electrolytes (SSEs) have led to great progress in the development of all-solid-state batteries (ASSBs);however, there are obstacles to their application such as poor interfacial stability, scalability challenges, production safety and sustainability of ASSBs which still demand prompt solution. In Nature Nanotechnology, Tan and colleagues summarize solutions to overcome some major fundamental obstacles faced by the ASSB community。

关键词： state fundamental prompt

Mapping Human Pluripotent Stem Cell-derived Erythroid Differentiation by Single-cell Transcriptome Analysis

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Genomics, Proteomics & Bioinformatics 2021年第3期19卷 358-376页

作者： Zijuan xin wei Zhang Shangjin gong Junwei Zhu Yanming Li Zhaojun Zhang Xiangdong Fang CAS Key Laboralory of Genome Science and Information Beijing Institute of GenomicsChinese Academy of Sciences/China National Center of BioinformationBeijing 100101China College of Life Sciences University of Chinese Academy of SciencesBejing 100049China Sino-Danish College University of Chinese Academy of SciencesBejing 100190.China Institute for Stem Cell and Regeneration Chinese Academy of SciencesBeijing 100101China Bejig Key Laboratory of Genome and Precision Medicine Technologies Beijing 100101China

There is an imbalance between the supply and demand of functional red blood cells(RBCs)in clinical *** imbalance can be addressed by regenerating RBCs using several in vitro *** pluripotent stem cells(iPSCs)can handle the low supply of cord blood and the ethical issues in embryonic stem cell research,and provide a promising strategy to eliminate immune ***,no complete single-cell level differentiation pathway exists for the iPSC-derived erythroid differentiation *** this study,we used iPSC line BC1 to establish a RBC regeneration *** 10X Genomics single-cell transcriptome platform was used to map the cell lineage and differentiation trajectory on day 14 of the regeneration *** observed that iPSC differentiation was not synchronized during embryoid body(EB)*** cells(on day 14)mainly consisted of mesodermal and various blood cells,similar to the yolk sac *** identified six cell classifications and characterized the regulatory transcription factor(TF)networks and cell-cell contacts underlying the *** undergo two transformations during the differentiation trajectory,accompanied by the dynamic expression of cell adhesion molecules and estrogen-responsive *** identified erythroid cells at different stages,such as burst-forming unit erythroid(BFU-E)and orthochromatic erythroblast(ortho-E)cells,and found that the regulation of TFs(e.g.,TFDP1 and FOXO3)is erythroid-stage *** erythroid cells were identified in our *** study provides systematic theoretical guidance for optimizing the iPSC-derived erythroid differentiation system,and this system is a useful model for simulating in vivo hematopoietic development and differentiation.

关键词： scRNA-seq iPSC Hematopoiesis Erythropoiesis Differentiation trajectory

Effects and mechanism of Chinese medicine Jiawei Yupingfeng in a mouse model of allergic rhinitis

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Journal of Integrative Medicine 2021年第4期19卷 354-361页

作者： Hui Chen wei Feng Ye Lu Yi Yang Zhong-hai xin Man Li Li xin Ying-di gong Department of Otolaryngology Wangjing HospitalChina Academy of Chinese Medical SciencesBeijing 100102China

Objective: Chinese medicine has the potential to modulate allergic rhinitis(AR). There have been studies investigating the treatment efficacy of Yupingfeng San, alone or in combination with other ingredients, in AR, though few have studied the potential mechanisms of these drugs. In the present study, we measured the effects of Jiawei Yupingfeng(JWYPF), a traditional Chinese medicine formula, on mice with ovalbumin-induced AR and explored its underlying mechanism of ***: Forty BALB/c mice were randomly divided into normal control, allergy control and two treatment groups of ten mice each. In the normal control group, mice were sensitized and challenged with saline. The mice in the allergy control and treatment groups were sensitized and challenged with ovalbumin and aluminum hydroxide gel. The treatments of JWYPF and Nasonex were administered intranasally in the AR mice for one week. Several signs of allergic inflammation, such as nasal eosinophils and inflammatory cytokines, were measured to determine the underlying ***: Mice in the JWYPF and Nasonex groups had significantly lower AR symptom scores than those in the allergy control group(the mean differences between JWYPF and the allergy control, and Nasonex and the allergy control were -2.00 ± 0.35 and -2.40 ± 0.32). After treatment with JWYPF and Nasonex, the levels of ovalbumin-specific Ig E and histamine were significantly reduced, as were the levels of interlukin-4 and transforming growth factor-b, while interferon-c levels were increased(all P < 0.0001,vs. allergy control). These two treatments also significantly inhibited eosinophil and mast cell infiltration into the nasal cavity but were not statistically different from ***: JWYPF has a potential therapeutic effect on AR via adjusting the rebalance of T helper 1 and T helper 2.

关键词： Chinese medicine Jiawei Yupingfeng Allergic rhinitis Mouse Inflammatory cytokines

NMDAR-dependent somatic potentiation of synaptic inputs is correlated withβamyloid-mediated neuronal hyperactivity

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Translational Neurodegeneration 2021年第3期10卷 432-446页

作者： Yifei Bao xin Yang Yi Fu Zhengyan Li Ru gong wei Lu MOE Key Laboratory of Developmental Genes and Human Disease School of Life Science and TechnologySoutheast UniversityNanjing 210096China Department of Neurology Huashan HospitalInstitute for Translational Brain ResearchState Key Laboratory of Medical NeurobiologyMOE Frontier Center for Brain ScienceFudan UniversityShanghai 200032China Co-Innovation Center of Neuroregeneration Nantong UniversityNantong 226001China

Background:βAmyloid(Aβ)-mediated neuronal hyperactivity,a key feature of the early stage of Alzheimer’s disease(AD),is recently proposed to be initiated by the suppression of glutamate ***,the underlying mechanism by which the impaired glutamate reuptake causes neuronal hyperactivity remains *** suppression of the glutamate reuptake causes accumulation of ambient glutamate that could difuse from synaptic sites at the dendrites to the soma to elevate the tonic activation of somatic N-methyl-D-aspartate receptors(NMDARs).However,less attention has been paid to the potential role of tonic activity change in extrasynaptic glutamate receptors(GluRs)located at the neuronal soma on generation of neuronal ***:Whole-cell patch-clamp recordings were performed on CA1 pyramidal neurons in acute hippocampal slices exposed to TFB-threo-β-benzyloxyaspartic acid(TBOA)or human Aβ_(1-42) peptide oligomer.A series of dendritic patch-clamp recordings were made at diferent distances from the soma to identify the location of the changes in synaptic ***,single-channel recording in the cell-attached mode was performed to investigate the activity changes of single NMDARs at the ***:Blocking glutamate uptake with either TBOA or the human Aβ_(1-42) peptide oligomer elicited potentiation of synaptic inputs in CA1 hippocampal ***,this potentiation specifcally occurred at the soma,depending on the activation of somatic GluN2B-containing NMDARs(GluN2B-NMDARs)and accompanied by a substantial and persistent increment in the open probability of somatic *** the activity of GluN2B-NMDARs at the soma completely reversed both the TBOA-induced or the Aβ_(1-42)-induced somatic potentiation and neuronal ***:The somatic potentiation of synaptic inputs may represent a novel amplifcation mechanism that elevates cell excitability and thus contributes to neuronal hyperactivity initiated by impai

关键词： NMDA receptor Hyperactivity Somatic modifcation Alzheimer’s disease

Precise and efficient Chinese license plate recognition in the real monitoring scene of intelligent transportation system

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The Journal of China Universities of Posts and Telecommunications 2022年第3期29卷 1-14页

作者： Jia wei gong Chao School of Computer Science and Information Engineering Hefei University of TechnologyHefei 230009China

In this paper, the performance of you only look once(YOLO) series detectors on Chinese license plate recognition(LPR) in the real intelligent transportation system(ITS) monitoring scene is investigated. Specially, a precise and efficient automatic license plate recognition(ALPR) system based on the YOLOv4 detector is proposed. The proposed ALPR system contains three stages including vehicle detection, license plate detection(LPD) and LPR. In vehicle detection stage, YOLOv4 detector is directly applied. In LPD stage, YOLOv4-tiny detector is exploited. In the last stage, the YOLOv4-tiny detector with attention mechanism for LPR is proposed to use. In addition, a large Chinese license plate dataset containing 10 500 images collected from all 31 provinces in the Chinese mainland is created. This Chinese license plate dataset is named Hefei University of Technology license plate version 1(HFUT-LP v1). Particularly, HFUT-LP v1 dataset is collected in the real ITS monitoring scene. In order to compare the performance of different object detection algorithms for ALPR, a variety of object detection algorithms are used to make a comprehensive performance evaluation. Experimental results show that the proposed ALPR system achieves very high accuracy and has very fast processing speed, which is suitable for real-time LPR.

关键词： license plate detection(LPD) license plate recognition(LPR) YOLOv4-tiny detector attention mechanism intelligent transportation

The low-latitude sodium layer:comparative data from lidar observations at Hainan,China and São Paulo,Brazil

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Earth and Planetary Physics 2025年第1期9卷 39-53页

作者： Fang Wu Jing Jiao GuoTao Yang LiFang Du ZhengKuan Liu HaoRan Zheng Jixin Guo ShaoHua gong YaJun Zhu State Key Laboratory of Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China Hainan National Field Science Observation and Research Observatory for Space Weather National Space Science CenterChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China China-Brazil Joint Laboratory for Space Weather NSSC/INPESão Josédos Campos 12227-010Brazil School of Physics and Electronics Engineering Hainan Normal UniversityHaikou 571158China

Physical and chemical processes observed in the mesosphere and thermosphere above the Earth’s low latitudes are complex and highly interrelated to activity in the low-latitude *** sodium detected by lidar can yield clues to dynamic and chemical processes in these spatial layers above the Earth’s *** paper is based on sodium layer data collected at two low-latitude stations,one in the northern hemisphere and one in the *** low-latitude sodium layer exhibits conspicuous seasonal variations in shape,density,and altitude;these variations are similar between Earth’s hemispheres:sodium layer density at both stations reaches its seasonal maximum in autumn and minimum in ***,maximal Na density over Brazil is greater than that over *** variations of Na density above the two low-latitude stations are also similar;at both,maxima are observed before *** variations of the Na layer over Brazil that differ from those observed in the northern hemisphere may be related to the South Atlantic Magnetic Anomaly(SAMA)or fountain *** suggest that low-latitude Na layer data may provide useful additional evidence that could significantly improve the low-latitude part of the WACCM-Na model.

关键词： metallic sodium layer seasonal variation nocturnal variation lidar

Deep neural network for remote-sensing image interpretation: status and perspectives

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National Science Review 2019年第6期6卷 1082-1086页

作者： Jiayi Li xin Huang Jianya gong School of Remote Sensing and Information Engineering Wuhan University State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan University

Deep neural networks(DNNs) refer to end-to-end mappings(i.e. from data to information) by stacking a large number of filters learned from massive samples. By courtesy of the comprehensive Earth observation platforms and convenient data access, remote-sensing practitioners are dealing with very large and ever-growing data volumes, which call for fast and transferrable machine-learning

关键词： status and perspectives image Deep neural network for remote-sensing image interpretation

Relationship between ecological stoichiometry and plant community diversity in the upper reaches of Tarim River,northwestern China

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Journal of Arid Land 2020年第2期12卷 227-238页

作者： ZHAO Jingjing gong Lu CHEN xin College of Resources and Environment Science Xinjiang UniversityUrumqi 830046China Key Laboratory of Oasis Ecology Xinjiang UniversityUrumqi 830046China

Changes in ecological stoichiometry reflect nitrogen(N),phosphorus(P)and both N and P limitations in a plant community,which in turn affect plant diversity of the ***,the relationship between plant community diversity and ecological stoichiometry has not yet been fully researched in arid and semi-arid *** stoichiometry and plant community diversity indices of eighteen communities in the upper reaches of Tarim River,northwestern China,were analyzed by multivariate analysis of variance in *** correlation between ecological stoichiometry and plant community diversity was assessed by redundancy analysis(RDA).Results indicated that the Margalef index was significantly correlated with carbon(C)and P concentrations,the Simpson index and Shannon-Weaner index were significantly correlated with plant C concentration,and the Pielou index was significantly correlated with plant C and N ***,C:N and C:P ratios had significant impacts on plant community *** results highlight the importance of ecological stoichiometry in driving plant community diversity in the upper reaches of Tarim River,northwestern China.

关键词： Margalef index Simpson index Shannon-Weaner index redundancy analysis Tarim River