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Classical Chinese Herbal Formulas in the Treatment of Coronary Heart Disease: A Narrative Review

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Chinese Journal of Integrative Medicine 2021年第1期27卷 70-79页

作者： lu xin-hui LI Jun Southern Branch of Guang'anmen Hospital China Academyof Chinese Medical SciencesBeijing(102618)China Department of Cardiology Guang'anmen HospitalChinaAcademy of Chinese Medical SciencesBeijing(100053)China

Objective:To summarize the current evidence for 8 frequently prescribed Chinese herbal formulas(CHF)as treatments for angina pectoris in patients with coronary heart disease(CHD)and the associated adverse ***:Seven electronic databases were screened from their inception through July 2018 for all evidence related to classical CHF for the treatment of patients with ***:CHF improves CHD outcomes in terms of angina pectoris,electrocardiogram results,Chinese medicine syndromes and biomarkers *** combination of CHF and Western medicine(WM)is more effective on CHD than WM *** use of CHF to treat CHD shows the same or better clinical effects as the use of WM *** 8 investigated CHF do not induce hepatic and renal toxicity or other serious adverse ***:The safety and efficacy of 8 frequently prescribed herbal formulas for treating CHD have been confirmed in many *** findings of these studies are positive but should be interpreted cautiously due to the poor methodological quality of the randomized controlled trials(RCTs)and *** high-quality,multi-center,large-sample RCTs should be performed to confirm these results.

关键词： Chinese herbal formulas coronary heart disease complementary and alternative medicine review

Environmental changes in Jiaozhou Bay of northern China during the past 90 years using metals and biogenic elements in sediments

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Journal of Environmental Sciences 2017年第3期29卷 301-312页

作者： Zhao-hui Wang xin Guo Ke Zhang xin-xin lu College of Life Science and Technology Key Laboratory of Eutrophication and Red Tide Prevention of Guangdong Higher Education InstitutesJinan UniversityGuangzhou 510632China

Metals and biogenic elements were analyzed from surface sediments and a 100 cm core collected from Jiaozhou Bay in July 2009, to determine how the environment has changed over the past 90 years due to increasing anthropogenic influences in this region. High concentrations of biogenic silica （BSi） represented the dominance of diatoms in the bay. Most metals were lower than the marine sediment quality guidelines; however, Hg, Zn, and Mn were at polluted levels. The vertical profiles of biogenic elements and metals in the sediment core suggest that the most significant environmental changes occurred since the 1990s, and three stages could be defined：（1） before 1950, characterized by low concentrations of biogenic elements and metals; （2） between 1950 and 1990, displaying an obvious increase of rig and a slow increase ofbiogenic elements; （3） after 1990, reflected by a significant increase of total organic carbon （TOG）, total nitrogen （TN）, total phosphate （TP）, and most metals, but a decrease of BSi. Correlation and principal component analyses indicated that most metals originated from lithogenic sources, industrial and domestic discharges as well as maricultural activities.

关键词： MetalsBiogenic elementsSedimentsEnvironmental changesJiaozhou BayYellow Sea

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-lu Yu Li-Yun Zhou Xiao Huang xin-Yue Li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

Based on non-targeted metabolomics for differential components screening of Rosae Chinensis Flos and Rosae Rugosae Flos and their quality evaluation

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Traditional Medicine Research 2025年第2期10卷 1-15页

作者： Xu Liang Ni-hui Zhang Zhi-Lai Zhan Guang-lu Chang Yan Gao Xia Li Wen-Yuan Gao School of Pharmaceutical Science and Technology Faculty of MedicineTianjin UniversityTianjin 300193China State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs China Academy of Chinese Medical SciencesBeijing 100700China Key Laboratory of Modern Chinese Medicine Resources Research Enterprises Tianjin 300402China

Background:Rosa chinensis *** Rosa rugosa *** not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional *** two plants have some differences in efficacy,but the flower buds are easily confused for similar *** addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal ***,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography ***,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large *** compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and ***:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the *** principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four *** least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavon

关键词： Rosa chinensis Jacq. Rosa rugosa Thunb. metabolomics chemometrics multiple component quantification quality evaluation

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-Yu Zhao Juan-Han Yu Yi-Hua Wang Yi-xin Liu lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Microstructure and properties of joint for stirring brazing of dissimilar Al/Mg alloy during heating processes

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Rare Metals 2015年第4期34卷 245-250页

作者： hui-Bin Xu hui-Bin Sun hui Yang lu-xin Chi Jun Chen School of Materials Science and Engineering Chongqing University of Technology

In this paper, 2024 Al alloy and AZ31B Mg alloy were brazed with aid of stirring without flux in air. The effects of the brazing temperature on microstructure and shear strength of the joint were investigated. The diffusion zone is found at joint interface near Al base metal, which consists of Al-Zn-Sn solid solution. At the same time, continuous intermetallic compounds （IMCs） phase and broken ones are found at joint interface near Mg base metal, which mainly consists of the Mg2Sn phase. With the increase of the brazing temperature, the shear strength at the joint interface near A1 base metal rises gradually. On the contrary, that of the joint interface near Mg base metal obviously decreases.

关键词： Stirring brazing 2024 Al alloy AZ31B Mg alloy Temperature

Role of neuronal nitric oxide synthase and inducible nitric oxide synthase in intestinal injury in neonatal rats

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World Journal of Gastroenterology 2006年第27期12卷 4364-4368页

作者： hui lu Bing Zhu xin-Dong Xue Department of Pediatrics the Second Affiliated Hospital of China Medical University Shenyang 110004 Liaoning Province China Department of Cardiac Surgery the Second Affiliated Hospital of China Medical University Shenyang 110004 Liaoning Province China

AIM： TO investigate the dynamic change and role of neuronal nitric oxide synthase （nNOS） and inducible nitric oxide synthase （iNOS） in neonatal rat with intestinal injury and to define whether necrotizing enterocolitis （NEC） is associated with the levels of nitric oxide synthase （NOS） in the mucosa of the affected intestine tissue. METHODS： Wistar rats less than 24 h in age received an intraperitoneal injection with 5 mg/kg lipopolysaccharide （LPS）. Ileum tissues were collected at 1, 3, 6, 12 and 24 h following LPS challenge for histological evaluation of NEC and for measurements of nNOS and iNOS. The correlation between the degree of intestinal injury and levels of NOS was determined. RESULTS： The LPS-injected increase in injury scores pups showed a significant versus the control. The expression of nNOS protein and mRNA was diminished after LPS injection. There was a negative significant correlation between the nNOS protein and the grade of median intestinal injury within 24 h. The expression of iNOS protein and mRNA was significantly increased in the peak of intestinal injury. CONCluSION： nNOS and iNOS play different roles in LPS-induced intestinal injury. Caution should be exerted concerning potential therapeutic uses of NOS inhibitors in NEC.

关键词： Neuronal nitric oxide synthase Inducible nitric oxide synthase Necrotizing enterocolitis Rat Newborn

Integration of coal pyrolysis process with iron ore reduction： Reduction behaviors of iron ore with benzene-containing coal pyrolysis gas as a reducing agent

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Chinese Journal of Chemical Engineering 2016年第6期24卷 811-817页

作者： xin Li Helong hui Songgeng Li lu He Lijie Cui State Key Laboratory of Multiphase Complex Systems Institute of Process Engineering Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China

An integrated coal pyrolysis process with iron ore reduction is proposed in this article. As the first step, iron oxide reduction is studied in a fixed bed reactor using simulated coal pyrolysis gas with benzene as a model tar compound. Variables such as reduction temperature, reduction time and benzene concentration are studied. The carbon deposition of benzene results in the retarded iron reduction at low temperatures. At high temperatures over800 °C, the presence of benzene in the gas can promote iron reduction. The metallization can reach up to 99% in20 min at 900 °C in the presence of benzene. Significant increases of hydrogen and CO/CO2 ratio are observed in the gas. It is indicated that iron reduction is accompanied by the reforming and decomposition of benzene. The degree of metallization and reduction increases with the increasing benzene concentration. Iron oxide can nearly completely be converted into cementite with benzene present in the gas under the experimental conditions. No sintering is found in the reduced sample with benzene in the gas.

关键词： Coal pyrolysisIron reductionIntegrationTar effect

Advances in ethnopharmacology,phytochemistry and pharmacology of Erigerontis Herba and its Chinese medicine prescriptions

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Traditional Medicine Research 2025年第1期10卷 44-61页

作者： Yang Zhou Yuan-Yan Huang Ding-Yue Shang Ying Chen Meng Tian Cheng-Yu Jin xin lu Bing-Chun Yan Han-Qing Pang Institute of Translational Medicine School of MedicineYangzhou UniversityYangzhou 225009China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases Yangzhou UniversityYangzhou 225009China School of Medicine Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources Guangxi Normal UniversityGuiling 541004China.

Erigerontis Herba(EH),the dried whole plant of Erigeron breviscapus,is well-known for circulating blood,activating meridians to alleviate pain,expelling wind,and clearing away *** has been extensively utilized in southern China for the treatment of stroke hemiplegia,chest stuffiness and pains,rheumatic arthralgia,headache,and *** review focuses on the botany,ethnopharmacology,phytochemistry,pharmacology and toxicity of EH and its related prescriptions to offer new insights for prospective research of *** information about EH was retrieved from ancient records and books,PubMed,China National Knowledge Infrastructure,Chinese Pharmacopoeia,Web of Science,Doctoral and Master’s Theses,and various electronic *** is a member of Compositae family and is mainly grown in southern *** Chinese medicine records that EH has the effects of circulating blood and removing blood stasis,expelling wind,and removing cold,as well as relieving rigidity of muscle and relieving *** now,nearly 200 ingredients have been characterized from EH,including flavonoids,caffeoyls,aromatic acids,coumarins,pentacyclic terpenoids,volatile oil and other *** extracts,EH related prescriptions(Dengzhan Xixin injection,Dengzhan Shengmai capsules,etc.)or compounds(scutellarin,scutellarein,etc.)possessed obvious therapeutic effects of ischemic stroke,cerebral hemorrhage,myocardial infarction,Alzheimer’s disease,diabetes and its complications,gastric cancer,bone,and joint degenerative ***,the major active compound of EH,has been used as a quality *** no obvious toxicity of EH has been *** to its traditional applications,ethnopharmacology,phytochemistry,pharmacology,and toxicity,EH was applied as a valuable herb for clinical application in food and medicine *** several compounds have been shown to possess diverse biological activities,the underlying mechanisms of their actions remain *** fully exploi

关键词： Erigeron breviscapus traditional applications ethnopharmacology phytochemistry pharmacology