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TIME RESOLVED SPECTRA OF Eu(MBA)_3 PHEN COMPLEXES

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Chinese Chemical Letters 1993年第2期4卷 183-186页

作者： Lin Pei JIN Ming Zhao WANG Rui Fen WANG Department of Chemistry,Beijing Normal University,Beijing,100875Jian xin CHEN guang Zhi xu Institute of Chemistry,Academia Sinica,Beijing,100080

Time-resolved fluorescence spectra of europium methylbenzoates (MBA)with 1,10-phenanthroline(phen)have been measured at room *** each of the europium chelates,where the ligand triple states lie above the ~5D_1 level of Eu^(3-),the spectra providc evidence that the Eu^(3-) ~5D_0 state is populated by nonradiative energy transfer from the higher-lying ~5D_1,*** relaxation time for energy decay from ~5D_1 state is measured in the microcrystals to bc of the order of a few *** is suggested that the ligand C=0 and C=C stretching vibrations and Eu-O vibrations,chclate ring and benzene ring vibrations make important contributions to the relaxation *** ~5D\-1—~5D\-0 relaxation time of Eu- (p-MBA)_3phen is shorter than those of Eu(m-MBA)_3phen and Eu(o-MBA)_3phen since nonradiative degradation to ~5D_0 from ~5D_1 appears to be more strongly influenced by the E_u^(3+)sites in the former.

关键词： MBA TIME RESOLVED SPECTRA OF Eu PHEN COMPLEXES

Complete response of gallbladder cancer treated with gemcitabine and cisplatin chemotherapy combined with durvalumab:A case report and review of literature

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 226-232页

作者： Kai Chen xu Feng Yuan Shi xin-Lin Li Zheng-Rong Shi Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Gallbladder cancer(GBC)is the most common and aggressive subtype of biliary tract cancer(BTC)and has a poor prognosis.A newly developed regimen of gemcitabine,cisplatin,and durvalumab shows promise for the treatment of advanced ***,the efficacy of this treatment for GBC remains *** SUMMARY In this report,we present a case in which the triple-drug regimen exhibited marked effectiveness in treating locally advanced GBC,thus leading to a long-term survival benefit.A 68-year-old man was diagnosed with locally advanced GBC,which rendered him ineligible for curative *** three cycles of therapy,a partial response was *** one year of combined therapy,a clinical complete response was successfully *** maintenance therapy with durvalumab monotherapy resulted in a disease-free survival of 9 months for the *** patient experienced tolerable toxicities of reversible grade 2 nausea and *** adverse events were observed in the patient throughout the entirety of the *** The combination of gemcitabine and cisplatin chemotherapy with durvalumab was proven to be an effective treatment approach for advanced GBC,with manageable adverse *** research is warranted to substantiate the effectiveness of the combined regimen in the context of GBC.

关键词： Gallbladder cancer Chemotherapy Immunotherapy Durvalumab Complete response Case report

Homozygous phytosterolemia and a literature review:A case report

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World Journal of Clinical Cases 2025年第10期13卷 46-52页

作者： Chun-xin Jiang guang Yang Lian-Ping Shi Peng-Yu Su Department of Cardiovascular North China University of Science and Technology Affiliated HospitalTangshan 063000Hebei ProvinceChina

BACKGROUND Phytosterolemia,also known as sitosterolemia,is a rare autosomal recessive disease characterized by elevated plasma plant sterol levels and xanthomata,which is easily misdiagnosed as familial *** with homozygous phytosterolemia often have severe clinical manifestations,with xanthomata in childhood and premature *** patient had a milder clinical *** SUMMARY This report describes a patient with homozygous phytosterolemia who presented with only elevated cholesterol and low-density lipoprotein cholesterol(LDL-C)without xanthomata,arteriosclerosis,or hematological *** mutation of ABCG5 which encodes an ATP-binding cassette transporter,was detected by whole exome sequencing and diagnosed as *** of the patient’s plasma plant sterol levels detected significant elevations in stigmasterol,rapeseed oil-derived plant sterol,andβ-glutaminol *** was started and a low plant sterol diet was *** patient’s blood lipid profile was reexamined one month later and showed significant decreases in total cholesterol and LDL-C *** has similar clinical features as familial hypercholesterolemia,is highly susceptible to misdiagnosis,and has a very low incidence,and therefore clinicians need to consider a genetic diagnosis of a definitively hyperlipidemic disorder when statin drugs fail to lower lipid *** Phytosterolemia is easily misdiagnosed as familial hypercholesterolaemia and can be treated by dietary modification and cholesterol absorption inhibitors to lower blood lipids.

关键词： Hypercholesterolemia Cholesterol Low-density lipoprotein Phytosterolemia Liquid chromatography ABCG5/ABCG8 Sitosterolemia

Predicting colorectal adenomatous polyps in patients with chronic liver disease: A novel nomogram

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World Journal of Gastroenterology 2025年第2期31卷 71-84页

作者： Yu-Qin Li Wen-Tao Kuai Lin Chen Ming-Hui Zeng xue-Mei Tao Jia-xin Han Yue-Kui Wang Lian-xin xu Li-Ying Ge Yong-Gang Liu Shuang Li Liang xu Yu-Qiang Mi Clinical School of the Second People’s Hospital Tianjin Medical UniversityTianjin 300192China Department of Hepatology Tianjin Second People’s HospitalTianjin 300192China Department of Pathology Clinical School of the Second People’s HospitalTianjin 300110China Endoscopy Center Tianjin Second People’s HospitalTianjin 300192China

BACKGROUND Colorectal polyps are commonly observed in patients with chronic liver disease(CLD)and pose a significant clinical concern because of their potential for *** To explore the clinical characteristics of colorectal polyps in patients with CLD,a nomogram was established to predict the presence of adenomatous polyps(AP).METHODS Patients with CLD who underwent colonoscopy at Tianjin Second People’s Hospital from January 2020 to May 2023 were *** data including laboratory results,colonoscopy findings,and pathology reports were *** variables for the nomogram were identified through least absolute shrinkage and selection operator regression,followed by multivariate logistic *** performance of the model was evaluated using the area under the receiver area under curve,as well as calibration curves and decision curve *** The study enrolled 870 participants who underwent colonoscopy,and the detection rate of AP in patients with CLD was 28.6%.Compared to individuals without polyps,six risk factors were identified as predictors for AP occurrence:Age,male sex,body mass index,alcohol consumption,overlapping metabolic dysfunction-associated steatotic liver disease,and serum ferritin *** novel nomogram(AP model)demonstrated an area under curve of 0.801(95%confidence interval:0.756-0.845)and 0.785(95%confidence interval:0.712-0.858)in the training and validation *** curves indicated good agreement among predicted and actual probabilities(training:χ^(2)=11.860,P=0.157;validation:χ^(2)=7.055,P=0.530).The decision curve analysis underscored the clinical utility of the nomogram for predicting the risk of *** The AP model showed reasonable accuracy and provided a clinical foundation for predicting the occurrence of AP in patients with CLD,which has a certain predictive value.

关键词： Metabolic dysfunction associated steatotic liver disease Fatty liver Chronic liver disease Colorectal adenomas Hepatitis Risk factors

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钢筋混凝土双曲线冷却塔施工工艺改进

施工技术 2002年第9期31卷 32-33页

作者：曹志新盛绪光山东省电力建设第一工程公司山东济南250100

菏泽电厂二期扩建工程 2座 5 5 0 0m2 钢筋混凝土双曲线冷却塔施工时采用旧钢模 ,为了保证公司提出的创精品目标 ,采用了多种新工艺 ,在未加大成本的前提下 ,提高了工艺质量 ,取得了理想效果。本文重在介绍采取的工艺改进。

关键词：钢筋混凝土双曲线冷却塔施工工艺

Resting-state brain network remodeling after different nerve reconstruction surgeries:a functional magnetic resonance imaging study in brachial plexus injury rats

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Neural Regeneration Research 2025年第5期20卷 1495-1504页

作者： Yunting Xiang Xiangxin xing xuyun Hua Yuwen Zhang xin xue Jiajia Wu Mouxiong Zheng He Wang Jianguang xu School of Rehabilitation Science Shanghai University of Traditional Chinese MedicineShanghaiChina Engineering Research Center of Traditional Chinese Medicine Intelligent Rehabilitation Ministry of EducationShanghaiChina Department of Rehabilitation Medicine Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Department of Traumatology and Orthopedics Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence(Fudan University) Ministry of EducationShanghaiChina Human Phenome Institute Fudan UniversityShanghaiChina

Distinct brain remodeling has been found after different nerve reconstruction strategies,including motor representation of the affected ***,differences among reconstruction strategies at the brain network level have not been *** study aimed to explore intranetwork changes related to altered peripheral neural pathways after different nerve reconstruction surgeries,including nerve repair,endto-end nerve transfer,and end-to-side nerve ***–Dawley rats underwent complete left brachial plexus transection and were divided into four equal groups of eight:no nerve repair,grafted nerve repair,phrenic nerve end-to-end transfer,and end-to-side transfer with a graft sutured to the anterior upper ***-state brain functional magnetic resonance imaging was obtained 7 months after *** independent component analysis algorithm was utilized to identify group-level network components of interest and extract resting-state functional connectivity values of each voxel within the *** in intra-network resting-state functional connectivity were compared among the *** muscle reinnervation was assessed by behavioral observation(elbow flexion)and *** results showed that alterations in the sensorimotor and interoception networks were mostly related to changes in the peripheral neural *** repair was related to enhanced connectivity within the sensorimotor network,while end-to-side nerve transfer might be more beneficial for restoring control over the affected limb by the original motor *** thalamic-cortical pathway was enhanced within the interoception network after nerve repair and end-to-end nerve *** areas related to cognition and emotion were enhanced after end-to-side nerve *** study revealed important brain networks related to different nerve *** networks may be potential targets for enhancing motor recovery.

关键词： brain functional networks end-to-end nerve transfer end-to-side nerve transfer independent component analysis nerve repair peripheral plexus injury resting-state functional connectivity

AP1000主设备大型锻件不符合项分析与预防

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压力容器 2016年第10期33卷 66-73页

作者：马蒙金鑫袁旭光梅雪强湖南桃花江核电有限公司湖南益阳413000

AP1000主设备锻件是反应堆压力容器、蒸汽发生器等主设备制造过程中难度最大的部分,其对设备的质量和进度影响重大,并且在制造过程中极易产生不符合项。通过对主设备锻件制造过程中常见的不符合项进行分析,得出产生不符合项的主要原因,... 详细信息

AP1000主设备锻件是反应堆压力容器、蒸汽发生器等主设备制造过程中难度最大的部分,其对设备的质量和进度影响重大,并且在制造过程中极易产生不符合项。通过对主设备锻件制造过程中常见的不符合项进行分析,得出产生不符合项的主要原因,提出了大锻件常见不符合项的处理措施及预防方案。为有效避免和减少主设备锻件制造过程中的不符合项,提高锻件质量,保证锻件制造进度提供了参考,也为主设备采购方在设备监造工作中控制锻件不符合项提供了指导。

关键词： AP1000主设备锻件不符合项分析与处理

Z-pinch一维时空分辨x射线辐射功率测量系统

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物理学报 2003年第5期52卷 1203-1206页

作者：徐荣昆李正宏郭存杨建伦李林波宋凤军宁佳敏夏广新许泽平中国工程物理研究院核物理与化学研究所绵阳621900

采用狭逢、红光闪烁体、光纤阵列、条纹相机、像增强器等元件组成x射线辐射功率时空分辨测量系统 ,该系统具有对x射线能量响应平坦 ,可有效屏蔽本底光干扰的优点 ,在喷气Z pinch实验中成功获得内爆等离子体x射线辐射的轴向分布图像 .文... 详细信息

采用狭逢、红光闪烁体、光纤阵列、条纹相机、像增强器等元件组成x射线辐射功率时空分辨测量系统 ,该系统具有对x射线能量响应平坦 ,可有效屏蔽本底光干扰的优点 ,在喷气Z pinch实验中成功获得内爆等离子体x射线辐射的轴向分布图像 .文中对系统结构、参数和使用情况进行了介绍。

关键词： Z-箍缩等离子体物理一维时空分辨X射线辐射功率测量系统内爆轴向分布图像

A Middle Triassic stem-neopterygian fish from China sheds new light on the peltopleuriform phylogeny and internal fertilization

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Science Bulletin 2016年第22期61卷 1766-1774页

作者： guang-Hui xu xin-Ying Ma Key Laboratory of Vertebrate Evolution and Human Origins of Chinese Academy of Sciences Institute of Vertebrate Paleontology and Paleoanthropology Chinese Academy of Sciences

Internal fertilization and viviparity are easily observed and well studied in living neopterygian fishes(14teleostean families), but they are difficult to identify in extinct taxa due to the limitation of the fossil record. The Peltopleuriformes from the Middle to Late Triassic of Europe and South China are a stem group of Neopterygii that may have first evolved internal fertilization and viviparity in this clade because they show a highly modified anal fin in presumed males resembling the intromittent organ in living viviparous teleosts. Until recently, Peltopleurus lissocephalus and P. rugosus from the Ladinian/Anisian boundary(*242 Ma) of Monte San Giorgio area in Switzerland and Italy represent the oldest record of Peltopleuriformes, and the phylogenetic interrelationships of this group remain controversial. Here, we report the discovery of a new peltopleuriform, Peltopleurus nitidus sp. nov., based on eleven well-preserved specimens from the early Middle Triassic(Pelsonian, Anisian, *244 Ma)of Luoping, eastern Yunnan, China. The discovery documents the oldest convincing peltopleuriform, extending the geological range of this clade by proximately two million years. Results of the phylogenetic analysis recover *** at the base of Peltopleuridae, and provide robust support for the sister-group relationships of Peltopleuridae with Thoracopteridae within the Peltopleuriformes. The male anal fin of P. nitidus shows a primitive condition unknown in other peltopleuriforms. Comparative studies of the male anal fin in P. nitidus and other peltopleuriforms shed new light on the internal fertilization in this group.

关键词： Sexual dimorphism Viviparity Peltopleuridae Thoracopteridae Triassic